Nitric oxide signaling mechanisms in the forearm vasculature of pregnant women

2001 ◽  
Vol 185 (2) ◽  
pp. 420 ◽  
Author(s):  
Dilly O.C. Anumba ◽  
Gary A. Ford ◽  
Stephen C. Robson
Keyword(s):  
Nitric Oxide ◽  
Pregnant Women ◽  
Nitric Oxide Signaling ◽  
Signaling Mechanisms

scholarly journals Statin-Induced Nitric Oxide Signaling: Mechanisms and Therapeutic Implications

2019 ◽  
Vol 8 (12) ◽  
pp. 2051 ◽  
Author(s):  
Armita Mahdavi Gorabi ◽  
Nasim Kiaie ◽  
Saeideh Hajighasemi ◽  
Maciej Banach ◽  
Peter E. Penson ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Blood Pressure ◽  
Atherosclerotic Plaques ◽  
Therapeutic Effects ◽  
Therapeutic Implications ◽  
Nitric Oxide Signaling ◽  
Beneficial Effects ◽  
Signaling Mechanisms ◽  
Neurological Injuries

In addition to their cholesterol-lowering effects, statins are associated with pleiotropic effects including improvements in heart failure (HF), reduced blood pressure, prevention of the rupture of atherosclerotic plaques and improved angiogenesis. In addition to these cardiovascular benefits, statins have been implicated in the treatment of neurological injuries, cancer, sepsis, and cirrhosis. These cholesterol-independent beneficial effects of statins are predominantly mediated through signaling pathways leading to increased production and bioavailability of nitric oxide (NO). In this review, the mechanistic pathways and therapeutic effects of statin-mediated elevations of NO are described and discussed.

scholarly journals Nitric Oxide Signaling in Plants

Plants ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1550
Author(s):  
John T. Hancock
Keyword(s):  
Nitric Oxide ◽  
Cell Signaling ◽  
Developmental Stages ◽  
Physiological Responses ◽  
Post Translational Modifications ◽  
Nitric Oxide Signaling ◽  
Signaling Mechanisms ◽  
Oxide Synthase ◽  
Signaling Components ◽  
Aperture Closure

Nitric oxide (NO) is an integral part of cell signaling mechanisms in animals and plants. In plants, its enzymatic generation is still controversial. Evidence points to nitrate reductase being important, but the presence of a nitric oxide synthase-like enzyme is still contested. Regardless, NO has been shown to mediate many developmental stages in plants, and to be involved in a range of physiological responses, from stress management to stomatal aperture closure. Downstream from its generation are alterations of the actions of many cell signaling components, with post-translational modifications of proteins often being key. Here, a collection of papers embraces the differing aspects of NO metabolism in plants.

scholarly journals Role of β-Adrenergic Receptors and Nitric Oxide Signaling in Exercise-Mediated Cardioprotection

Physiology ◽  
2013 ◽  
Vol 28 (4) ◽  
pp. 216-224 ◽  
Author(s):  
John W. Calvert ◽  
David J. Lefer
Keyword(s):  
Nitric Oxide ◽  
Risk Factors ◽  
Adrenergic Receptors ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Nitric Oxide Signaling ◽  
Factors Associated ◽  
Cardioprotective Effects ◽  
Β Adrenergic Receptors

Exercise promotes cardioprotection in both humans and animals not only by reducing risk factors associated with cardiovascular disease but by reducing myocardial infarction and improving survival following ischemia. This article will define the role that nitric oxide and β-adrenergic receptors play in mediating the cardioprotective effects of exercise in the setting of ischemia-reperfusion injury.

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