Cysteamine: a human health dietary additive with potential to improve livestock growth rate and efficiency

2016 ◽  
Vol 56 (8) ◽  
pp. 1330 ◽  
Author(s):  
M. C. Barnett ◽  
R. S. Hegarty
Keyword(s):  
Growth Rate ◽  
Growth Responses ◽  
Feed Conversion ◽  
Nutrition And Health ◽  
Short Term ◽  
Nutrient Utilisation ◽  
Use Efficiency ◽  
Potential Use ◽  
Stimulation Of ◽  
Somatotrophic Axis

Cysteamine is a biological compound produced in the gastrointestinal tract and hypothalamus of all animals that acts on the somatotrophic axis. Cysteamine is finding increasing application in human medicine and also as a natural, in-feed growth promotant for monogastric and ruminant livestock that increases feed conversion efficiency, growth rate and leanness. It improves nutrient digestion and absorption by increasing portal-drained viscera blood flow and net portal absorption, while also reducing gastroenteropancreatic, plasma and hypothalamus concentrations of the inhibitory hormone, somatostatin (SRIF). Dietary inclusion rates required to achieve growth responses are typically about 10 times higher in ruminants than those required for pigs, but it is unclear whether ruminal breakdown of cysteamine is contributing to this difference. While short-term stimulation of growth, milk production and improved feed use efficiency are apparent, studies over longer periods are required, especially in breeding animals, due to the process of SRIF depletion being reversible. This review provides an overview of cysteamine’s mode of action in improving nutrient utilisation and its application in human nutrition and health, as well as its potential use as a growth promotant in the livestock industries.

scholarly journals Stimulation of Short-term Plant Growth by Glycerol Applied as Foliar Sprays and Drenches under Greenhouse Conditions

HortScience ◽  
2011 ◽  
Vol 46 (12) ◽  
pp. 1650-1654 ◽  
Author(s):  
Brent Tisserat ◽  
Amy Stuff
Keyword(s):  
Zea Mays ◽  
Foliar Spray ◽  
Shoot Length ◽  
Growth Responses ◽  
Short Term ◽  
Mentha Spicata ◽  
Foliar Sprays ◽  
Diverse Plant Species ◽  
Diverse Plant ◽  
Stimulation Of

The effects of aqueous solutions applied as foliar spray and drench applications of glycerol were tested on the ‘Chantenay’ carrot (Daucus carota L.) family Apiaceae, corn (Zea mays L.) family Poaceae, and spearmint (Mentha spicata L.) family Lamiaceae under greenhouse conditions. Foliar sprays and drenches were administered to carrots at concentrations of 0, 1, 3, 5, 10, 25, or 50 ml·L−1. Fresh weights, dry weights, and taproot diameter from carrot seedlings sprayed with a solution containing 5 mL·L−1 (50 mm) glycerol increased 105.6%, 158.4%, and 53.8%, respectively, when compared with untreated carrots. Foliar sprays were administered to corn at concentrations of 0, 0.1, 0.3, 0.5, and 1 ml·L−1 and spearmint at concentrations of 0, 1, 5, and 10 mL·L−1. Growth responses increased in corn and spearmint by using certain glycerol concentrations. Fresh weights, dry weights, and shoot length from corn seedlings sprayed with a solution containing 0.5 mL·L−1 (5 mm) glycerol increased 83.5%, 154.6%, and 90.9%, respectively, when compared with untreated corn. Fresh weights, dry weights, and shoot length from mint plants sprayed with a solution containing 5 mL·L−1 (50 mm) glycerol increased 46.6%, 68.7%, and 102.5%, respectively, when compared with untreated plants. Glycerol applications can stimulate growth responses in diverse plant species.

scholarly journals The effect of frequency of feeding on the utilization of free lysine by growing pigs

1974 ◽  
Vol 31 (2) ◽  
pp. 237-242 ◽  
Author(s):  
E. S. Batterham
Keyword(s):  
Growth Rate ◽  
Significant Interaction ◽  
Control Diet ◽  
Live Weight ◽  
Growing Pigs ◽  
Growth Responses ◽  
Feed Conversion ◽  
Once Daily ◽  
Frequent Feeding ◽  
Feeding Regimen

1. Pigs from 20 to 47 kg live weight were given a wheat–safflower diet supplemented with either 0, 2 or 4 g L-lysine/kg either once daily or in six equal portions at intervals of 3 h.2. The addition of lysine at both levels significantly (P < 0.001) increased growth rate, feed conversion and lean content of the ham.3. Frequency of feeding had no effect on the response of pigs given the control diet.4. A significant interaction (P < 0.05) between frequency of feeding and lysine supplementation occurred for growth rate. Growth responses to the supplements of 2 and 4 g L-lysine/ kg with once-daily feeding were only 43 and 69% of those achieved under the frequent-feeding regimen.

Is money the creation of the state or the market? (On the “modern monetary theory” as described in the textbook by W. Mitchell, L. R. Wray and M. Watts “Macroeconomics”)

2020 ◽  
pp. 121-134
Author(s):  
S. A. Andryushin
Keyword(s):  
Public Debt ◽  
Scientific Community ◽  
Full Employment ◽  
Term Effect ◽  
Scientific Concept ◽  
Monetary Theory ◽  
Left Wing ◽  
Medium Term ◽  
Short Term ◽  
Stimulation Of

In 2019, a textbook “Macroeconomics” was published in London, on the pages of which the authors presented a new monetary doctrine — Modern Monetary Theory, MMT, — an unorthodox concept based on the postulates of Post-Keynesianism, New Institutionalism, and the theory of Marxism. The attitude to this scientific concept in the scientific community is ambiguous. A smaller part of scientists actively support this doctrine, which is directly related to state monetary and fiscal stimulation of full employment, public debt servicing and economic growth. Others, the majority of economists, on the contrary, strongly criticize MMT, arguing that the new theory hides simple left-wing populism, designed for a temporary and short-term effect. This article considers the origins and the main provisions of MMT, its discussions with the mainstream, criticism of the basic tenets of MMT, and also assesses possible prospects for the development of MMT in the medium term.

EFFECT OF ACTINOMYCIN D ON TSH-INDUCED STIMULATION OF THYROIDAL PROTEIN SYNTHESIS IN THE RAT

1974 ◽  
Vol 77 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Gustav Wägar
Keyword(s):  
Protein Synthesis ◽  
Actinomycin D ◽  
The Other ◽  
Leucine Incorporation ◽  
Short Term ◽  
Other Hand ◽  
Thyroid Glands ◽  
Translational Level ◽  
Stimulation Of

ABSTRACT Whether the short-term regulation of thyroidal protein synthesis by TSH occurs at the transcriptional or the translational level was tested by measuring the effect of actinomycin D (act D) on the TSH-induced stimulation of L-14C-leucine incorporation into the thyroidal proteins of rats. TSH was injected 6 h before the rats were killed. The thyroid glands were then removed and incubated in vitro in the presence of L-14C-leucine for 2 h. The pronounced stimulation of leucine incorporation in the TSH-treated animals was depressed as compared with controls but still significant even when the animals had been pre-treated with 100 μg act D 24 and 7 h before sacrifice. On the other hand, act D strongly decreased incorporation of 3H-uridine into RNA. Short-term regulation of thyroidal protein synthesis by TSH appears to be partly but not wholly dependent on neosynthesis of RNA. Hence regulation may partly occur at the translation level of protein synthesis.

SUBSTITUSI FERMENTASI BUNGKIL KELAPA SAWIT DALAM PAKAN BUATAN TERHADAP PERTUMBUHAN DAN KELANGSUNGAN HIDUP BENIH IKAN GURAMI (OSPHRONEMUS GOURAMY)

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Farida . ◽  
Eka Indah Raharjo ◽  
Arnis Maylinda Sari
Keyword(s):  
Growth Rate ◽  
Palm Oil ◽  
Palm Kernel ◽  
Specific Weight ◽  
Feed Conversion ◽  
Daily Growth Rate ◽  
Daily Growth ◽  
Average Growth ◽  
Fermentation Residue ◽  
Average Average

ABSTRAKPenelitian bertujuan untuk mengetahui penggunaan fermentasi bungkil kelapa sawit dalam pakan buatan.Penelitian menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan 3 ulangan.Susunan perlakuan adalah Perlakuan A : bungkil kelapa sawit 12%, Perlakuan B : fermentasi bungkil kelapa sawit 15%, Perlakuan C : fermentasi bungkil kelapa sawit 18%, Perlakuan D : fermentasi bungkil kelapa sawit 21%. Penelitian ini dilakukan selama 60 hari untuk mengetahui laju pertumbuhan spesifikberat, laju pertumbuhan harianpanjang, konversi pakan, kelangsungan hidup dan kualitas air sebagai penunjang.Hasil penelitian menunjukkan pemberian pakan buatan dengan fermentasi bungkil kelapa sawit menghasilkan respon yang baik terhadap pertumbuhan ikan gurami. Pemberian pakan buatan dengan fermentasi bungkil kelapa sawit 18% (perlakuan C), memberikan hasil terbaik dengan laju pertumbuhan dengan rata – rata laju pertumbuhan spesifik berat 1.502%, laju pertumbuhan harian panjang 4.06%, nilai konversi pakan rata – rata 3.48 dan kelangsungan hidup rata – rata 90%.Kata Kunci : Fermentasi Bungkil Kelapa Sawit, Ikan Gurami, Laju PertumbuhanThe study aims to determine the use of fermentation residue oil palm in artificial feed .Research using a completely randomized design ( CRD ), which consists of 4 treatment three replications.The composition of the treatment is the treatment  A : 12 % of palm oil cake , Treatment B : fermented palm oil cake 15 % , Treatment C : fermented palm oil cake 18 % , Treatment D : fermentation residue palm oil 21 %.This research was conducted for 60 days to determine the specific growth rate of heavy , long daily growth rate , feed conversion , survival and quality of water as a supporter.The results showed the artificial feeding with fermented palm cake to produce a good response to the growth of carp.Feeding artificially by fermentation cake palm oil 18 % ( treatment C ) , gives the best results with a growth rate with the average - average growth rate of the specific weight of 1.502 % daily growth rate long- 4:06 % , the value of feed conversion average - average 3:48 and median survival - average of 90 % .Keywords : Fermentation Palm Kernel Oil, Fish carp, Growth Rate

Electrical stimulation of referred sensation area alleviates phantom limb pain

2021 ◽  
pp. 1-10
Author(s):  
Michihiro Osumi ◽  
Daisuke Shimizu ◽  
Yuki Nishi ◽  
Shu Morioka
Keyword(s):  
Electrical Stimulation ◽  
Single Case ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Long Term Effects ◽  
Limb Pain ◽  
Short Term ◽  
Analgesic Effects ◽  
Stimulation Of

Background: Patients with brachial plexus avulsion (BPA) usually experience phantom sensations and phantom limb pain (PLP) in the deafferented limb. It has been suggested that evoking the sensation of touch in the deafferented limb by stimulating referred sensation areas (RSAs) on the cheek or shoulder might alleviate PLP. However, feasible rehabilitation techniques using this approach have not been reported. Objective: The present study sought to examine the analgesic effects of simple electrical stimulation of RSAs in BPA patients with PLP. Methods: Study 1: Electrical stimulation of RSAs for 60 minutes was conducted for six BPA patients suffering from PLP to examine short-term analgesic effects. Study 2: A single case design experiment was conducted with two BPA patients to investigate whether electrical stimulation of RSAs was more effective for alleviating PLP than control electrical stimulation (electrical stimulation of sites on side opposite to the RSAs), and to elucidate the long-term effects of electrical stimulation of RSAs. Results: Study 1: Electrical stimulation of RSAs evoked phantom touch sensations in the deafferented limb, and significantly alleviated PLP (p <  0.05). Study 2: PLP was alleviated more after electrical stimulation on RSAs compared with control electrical stimulation (p <  0.05). However, the analgesic effects of electrical stimulation on RSAs were observed only in the short term, not in the long term (p >  0.05). Conclusions: Electrical stimulation of RSAs not only evoked phantom touch sensation but also alleviated PLP in the short term. The results indicate that electrical stimulation of RSAs may provide a useful practical rehabilitation technique for PLP. Future studies will be required to clarify the mechanisms underlying immediate PLP alleviation via electrical stimulation of RSAs.

scholarly journals Gross Ammonification and Nitrification Rates in Soil Amended with Natural and NH4-Enriched Chabazite Zeolite and Nitrification Inhibitor DMPP

2021 ◽  
Vol 11 (6) ◽  
pp. 2605
Author(s):  
Giacomo Ferretti ◽  
Giulio Galamini ◽  
Evi Deltedesco ◽  
Markus Gorfer ◽  
Jennifer Fritz ◽  
...  
Keyword(s):  
Nitrification Inhibitor ◽  
Natural State ◽  
Silty Clay ◽  
Short Term ◽  
N Losses ◽  
15N Pool Dilution ◽  
Use Efficiency ◽  
Silty Clay Soil ◽  
N Use ◽  
15N Pool Dilution Technique

Using zeolite-rich tuffs for improving soil properties and crop N-use efficiency is becoming popular. However, the mechanistic understanding of their influence on soil N-processes is still poor. This paper aims to shed new light on how natural and NH4+-enriched chabazite zeolites alter short-term N-ammonification and nitrification rates with and without the use of nitrification inhibitor (DMPP). We employed the 15N pool dilution technique to determine short-term gross rates of ammonification and nitrification in a silty-clay soil amended with two typologies of chabazite-rich tuff: (1) at natural state and (2) enriched with NH4+-N from an animal slurry. Archaeal and bacterial amoA, nirS and nosZ genes, N2O-N and CO2-C emissions were also evaluated. The results showed modest short-term effects of chabazite at natural state only on nitrate production rates, which was slightly delayed compared to the unamended soil. On the other hand, the addition of NH4+-enriched chabazite stimulated NH4+-N production, N2O-N emissions, but reduced NO3−-N production and abundance of nirS-nosZ genes. DMPP efficiency in reducing nitrification rates was dependent on N addition but not affected by the two typologies of zeolites tested. The outcomes of this study indicated the good compatibility of both natural and NH4+-enriched chabazite zeolite with DMPP. In particular, the application of NH4+-enriched zeolites with DMPP is recommended to mitigate short-term N losses.

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