Improved Extraction Yield of Citral from Lemon Myrtle Using a Cellulose-Dissolving Ionic Liquid

2017 ◽  
Vol 70 (6) ◽  
pp. 699 ◽  
Author(s):  
Koki Munakata ◽  
Masahiro Yoshizawa-Fujita ◽  
Masahiro Rikukawa ◽  
Toyonobu Usuki
Keyword(s):  
Ionic Liquid ◽  
Natural Products ◽  
Ionic Liquids ◽  
Ammonium Chloride ◽  
Present Method ◽  
Extraction Yield ◽  
Natural Source

Lemon myrtle is the richest natural source of citral, which has potential medicinal applications. In this study, citral was extracted from lemon myrtle using cellulose-dissolving ionic liquids (ILs), 1-ethyl-3-methylimidazolium methylphosphonate ([C2mim][(MeO)(H)PO2]), N,N-diethyl-N-methyl-N-(2-methoxyethyl)ammonium chloride ([DEME]Cl), and N,N-diethyl-N-methyl-N-(2-methoxyethyl)ammonium 2-methoxyacetate ([DEME][MOAc]). The extraction yield of citral obtained using ILs was up to 2.1 times higher than that obtained using ethanol. The ILs could be recycled and reused nine times for the extraction of citral. The present method provides a greener process when compared with conventional approaches and may be applicable for the extraction of other natural products.

scholarly journals Effect of Ionic Liquid Surfactants on Coal Oxidation and Structure

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Weiqing Zhang ◽  
Shuguang Jiang ◽  
Tong Qin ◽  
Jianfeng Sun ◽  
Chaowei Dong ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Critical Micelle Concentration ◽  
Ammonium Chloride ◽  
Coal Oxidation ◽  
Thermal Stabilities ◽  
Oxidation Activity ◽  
Temperature Programmed Oxidation ◽  
Surface Activities ◽  
Temperature Programmed

The effects of six ionic liquids with surfactant property (1-hydroxyethyl-3-methyl imidazolium bis(trifluoromethylsulfonyl)imide ([HOEtMIm][NTf2]), 1-hydroxyethyl-3-methyl imidazolium tetrafluoroborate ([HOEtMIm][BF4]), 1-dodecyl-3- methyl imidazolium bromide ([C12MIm]Br), 1-tetradecyl-3- methyl imidazolium bromide ([C14MIm]Br), trioctyl methyl ammonium chloride ([N8,8,8,1])Cl, and tetraethyl ammonium chloride ([N2,2,2,2]Cl)) on the oxidation characteristics and functional groups of coal were studied by means of critical micelle concentration, surface tension, thermogravimetric analysis, temperature-programmed oxidation, and Fourier transform infrared spectroscopy (FTIR) measurements. The lower critical micelle concentration for the ionic liquids except the [N2,2,2,2]Cl suggests the favorable surface activity of these ionic liquids. The surface activities of [N8,8,8,1]Cl, [C14MIm]Br, [C12MIm]Br, and [HOEtMIm][NTf2] were high, while that of [N2,2,2,2]Cl was relatively lower. The thermal stabilities of [HOEtMIm][NTf2] and [HOEtMIm][BF4] were high, while those of [N8,8,8,1]Cl and [N2,2,2,2]Cl were lower. The oxidation activities of ionic liquid-mixed coals were weakened to different degrees except [N8,8,8,1]Cl-mixed coal, because of the poor thermal stability and decomposition of [N8,8,8,1]Cl accelerating the coal oxidation. The other five ionic liquids were suitable for inhibiting coal oxidation, particularly the [HOEtMIm][BF4] and [HOEtMIm][NTf2] with higher inhibition rate, longer inhibition time, and also better thermal stabilities. The activation energy results further confirmed such inhibition effect. The functional group results showed that treatment of ionic liquids on coal can change the contents of hydrogen bonds, aliphatic groups, and aromatic groups in coal. It was inferred that the [HOEtMIm][BF4], [HOEtMIm][NTf2], and [C14MIm]Br were more effectively to affect coal structure and decrease coal oxidation activity.

Partitioning Behavior of Penicillin G in Aqueous Two Phase System Based on Ionic Liquids

2013 ◽  
Vol 864-867 ◽  
pp. 324-327
Author(s):  
Bin Jiang ◽  
Zhi Biao Feng ◽  
Chun Hong Liu ◽  
Ying Cao Xu ◽  
Dong Mei Li ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Extraction Yield ◽  
Penicillin G ◽  
Phase System ◽  
Two Phase ◽  
Aqueous Two Phase System ◽  
Partitioning Behavior

An aqueous two-phase system (ATPS) was presented with hydrophilic ionic liquid 1-Butyl-3-methylimid-azolium tetrafluoroborate ([BmiBF4) and salts for the extraction of penicillin G in this paper. The phase forming abilities of different salts were investigated to choose a suitable salt.The partitioning behavior of penicillin G in the ATPS was investigated.Concentrations of (NH4)2SO4, penicillin G, and [BmiBF4 were evaluated to determine their effects on the extraction yield of penicillin G. It was found that extraction yield strongly depended on the concentration of [BmiBF4, penicillin and (NH4)2SO4. A high extraction yield around 93% was achieved with the following parameters: (NH4)2SO4 20% (wt%), penicillin 40000 ~ 45000 U/mL, [BmiBF4 20% (wt%).

scholarly journals Surface-active Ionic Liquids for Micellar Extraction of Piperine from Black Pepper

2013 ◽  
Vol 68 (10) ◽  
pp. 1129-1137 ◽  
Author(s):  
Anna K. Ressmann ◽  
Ronald Zirbs ◽  
Martin Pressler ◽  
Peter Gaertner ◽  
Katharina Bica
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Extraction Efficiency ◽  
Black Pepper ◽  
Extraction Yield ◽  
Micellar Solutions ◽  
Micellar Extraction ◽  
Surface Active ◽  
Isolation Media ◽  
Aqueous Micellar Solutions

We present the application of ionic liquid-aqueous micellar solutions as isolation media for the pharmaceutically active ingredient piperine from black pepper. Several surface-active ionic liquids including a biodegradable betaine derivative were used for the extraction of piperine, and a strong correlation between extraction yield and the critical micelle concentration of the respective ionic liquid was found. A scaled strategy for the isolation of piperine was developed that allowed recovery and recycling of the aqueous ionic liquid micellar solution for five runs without any loss in extraction efficiency.

scholarly journals A Design of Experiment Approach for Ionic Liquid-Based Extraction of Toxic Components-Minimized Essential Oil from Myristica fragrans Houtt. Fruits †

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2817 ◽  
Author(s):  
Daniela Lanari ◽  
Maria Marcotullio ◽  
Andrea Neri
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Experimental Design ◽  
Essential Oil ◽  
Extraction Yield ◽  
Methyl Eugenol ◽  
Innovative Methods ◽  
Myristica Fragrans ◽  
Myristica Fragrans Houtt ◽  
Nutmeg Essential Oil

The effect of the addition of ionic liquids (ILs) during the hydrodistillation of Myristica fragrans Houtt. (nutmeg) essential oil was studied. The essential oil of M. fragrans is characterized by the presence of terpenes, terpenoids, and of phenylpropanoids, such as methyl eugenol and safrole, that are regarded as genotoxic and carcinogenic. The aim of the work was to determine the best ionic liquid to improve the yield of the extraction of M. fragrans essential oil and decrease the extraction of toxic phenylpropanoids. Six ILs, namely 1,3-dimethylimidazolium chloride (1), 1,3-dimethylimidazolium dimethylphosphate (2), 1-(2-hydroxyethyl)-3-methylimidazolium chloride (3), 1-(2-hydroxyethyl)-3-methylimidazolium dimethylphosphate (4), 1-butyl-3-methylimidazolium chloride (5), and 1-butyl-3-methylimidazolium dimethylphosphate (6), were prepared by previously reported, innovative methods and then tested. An experimental design was used to optimize the extraction yield and to decrease the phenylpropanoids percentage using the synthesized ILs. The influence of the molarity of ILs was also studied. MODDE 12 software established 0.5 M 1-butyl-3-methylimidazolium chloride as the best co-solvent for the hydrodistillation of M. fragrans essential oil.

Temperature-responsive ionic liquids to set up a method for the simultaneous extraction and in situ preconcentration of hydrophilic and lipophilic compounds from medicinal plant matrices

2019 ◽  
Vol 21 (15) ◽  
pp. 4133-4142 ◽  
Author(s):  
Tong Wang ◽  
Qing Wang ◽  
Ping Li ◽  
Hua Yang
Keyword(s):  
Ionic Liquid ◽  
Natural Products ◽  
Ionic Liquids ◽  
Medicinal Plant ◽  
Lipophilic Compounds ◽  
Simultaneous Extraction ◽  
Temperature Responsive ◽  
Set Up ◽  
In Situ Preconcentration

An integrated switchable temperature-responsive ionic liquid based method which could simultaneously extract and in situ separate lipophilic and hydrophilic natural products was developed.

Mapping the “Extra Solvent Power, ESP” of Ionic Liquids for Monomers, Polymers and Globular Nanoparticles

2017 ◽  
Author(s):  
Jose A. Pomposo
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Linear Polymers ◽  
Green Solvents ◽  
Ionic Polymers ◽  
First Time ◽  
Solvent Power

Understanding the miscibility behavior of ionic liquid (IL) / monomer, IL / polymer and IL / nanoparticle mixtures is critical for the use of ILs as green solvents in polymerization processes, and to rationalize recent observations concerning the superior solubility of some proteins in ILs when compared to standard solvents. In this work, the most relevant results obtained in terms of a three-component Flory-Huggins theory concerning the “Extra Solvent Power, ESP” of ILs when compared to traditional non-ionic solvents for monomeric solutes (case I), linear polymers (case II) and globular nanoparticles (case III) are presented. Moreover, useful ESP maps are drawn for the first time for IL mixtures corresponding to case I, II and III. Finally, a potential pathway to improve the miscibility of non-ionic polymers in ILs is also proposed.

Dynamics of Ion Locking in Doubly Polymerized Ionic Liquids

2020 ◽  
Author(s):  
Swati Arora ◽  
Julisa Rozon ◽  
Jennifer Laaser
Keyword(s):  
Dielectric Constant ◽  
Ionic Liquid ◽  
Ionic Liquids ◽  
Ion Pairs ◽  
Polymer Chains ◽  
Ion Motion ◽  
Charged Species ◽  
Broadband Dielectric Spectroscopy ◽  
Covalently Linked ◽  
Insight Into

<div>In this work, we investigate the dynamics of ion motion in “doubly-polymerized” ionic liquids (DPILs) in which both charged species of an ionic liquid are covalently linked to the same polymer chains. Broadband dielectric spectroscopy is used to characterize these materials over a broad frequency and temperature range, and their behavior is compared to that of conventional “singly-polymerized” ionic liquids (SPILs) in which only one of the charged species is attached to the polymer chains. Polymerization of the DPIL decreases the bulk ionic conductivity by four orders of magnitude relative to both SPILs. The timescales for local ionic rearrangement are similarly found to be approximately four orders of magnitude slower in the DPILs than in the SPILs, and the DPILs also have a lower static dielectric constant. These results suggest that copolymerization of the ionic monomers affects ion motion on both the bulk and the local scales, with ion pairs serving to form strong physical crosslinks between the polymer chains. This study provides quantitative insight into the energetics and timescales of ion motion that drive the phenomenon of “ion locking” currently under investigation for new classes of organic electronics.</div>

Microwave Pretreatment of Vegetable Materials to Increase the Extraction Yield of Natural Products

2018 ◽  
Vol 69 (8) ◽  
pp. 1976-1979
Author(s):  
Ioana Asofiei ◽  
Ioan Calinescu ◽  
Adina Ionuta Gavrila ◽  
Daniel Ighigeanu ◽  
Diana Martin
Keyword(s):  
Natural Products ◽  
Chemical Composition ◽  
Phenolic Compounds ◽  
Total Phenolic Content ◽  
Phenolic Content ◽  
Extraction Yield ◽  
Total Phenolic ◽  
Microwave Pretreatment ◽  
Pretreatment Time ◽  
Conventional Extraction

It was designed and built a laboratory experimental installation (LEI) for the microwave pretreatment of vegetable materials. To study the influence of microwave pretreatment on the total phenolic content (TPC), a conventional extraction of polyphenols from treated and untreated fresh sea buckthorn leaves was performed. For short extraction times, the amount of phenolic compounds was higher for the extracts obtained from treated leaves, but a long pretreatment time (28 s) led to a decrease in TPC. The qualitative analysis showed that the chemical composition is not affected by the microwave pretreatment.

Ionic Liquid Assisted Synthesis of Some 2-Aminobenzenethiols

2019 ◽  
Vol 16 (7) ◽  
pp. 550-555
Author(s):  
Dinesh K. Jangid ◽  
Keshav L. Ameta ◽  
Surbhi Dhadda ◽  
Anjali Guleria ◽  
Prakash G. Goswami ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Comparative Study ◽  
Maximum Yield ◽  
Efficient Synthesis ◽  
Target Molecules ◽  
Presence And Absence

Ionic Liquid assisted efficient synthesis of some 2-aminobenzenethiols has been reported using three different Ionic Liquids (ILs) namely methylimidazolium tetrafluoroborate [MIM]+[BF4]−, methylimidazolium chloride [MIM]+[Cl]− and methylimidazolium nitrate [MIM]+[NO3]−. A comparative study has been carried out for the synthesis of target molecules in the presence and absence of IL, leading to conclusion that maximum yield has been observed with [MIM]+[BF4]−.

Dispersive Liquid-Liquid Microextraction Based on Ionic Liquid and Spectrophotometric Determination of Bilirubin in Biological Samples

2020 ◽  
Vol 16 (5) ◽  
pp. 652-659
Author(s):  
Asiye A. Avan ◽  
Hayati Filik
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Biological Samples ◽  
Urine Samples ◽  
Spectrophotometric Detection ◽  
Full Color ◽  
Dispersive Liquid Liquid Microextraction ◽  
Urine And Serum ◽  
Liquid Microextraction

Background: An Ionic Liquid-based based Dispersive Liquid-Liquid Microextraction (IL-DLLME) method was not applied to preconcentration and determination of bilirubin. Ionic Liquids (ILs) are new chemical compounds. In recent years, Ionic Liquids (ILs) have been employed as alternative solvents to toxic organic solvents. Due to these perfect properties, ILs have already been applied in many analytical extraction processes, presenting high extraction yield and selectivity for analytes. Methods: In this study, IL-DLLME was applied to biological samples (urine and serum) for the spectrophotometric detection of bilirubin. For bilirubin analysis, the full-color development was based on the reaction with periodate in the presence of hydrochloric acid. The high affinity of bilirubin for the ionic liquid phase gave extraction percentages above 98% in 0.3 M HCl solution. Results: Several IL-extraction parameters were optimized and room temperature ionic liquid 1-butyl- 1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide and ethanol were used as extraction and disperser solution. The linear range was found in the range of 0.5-6.0 μM (0.3-3.5 μg mL-1) and the limits of detection of the proposed method was 0.5 μM (0.3 μg mL-1). The proposed method was applied for the preconcentration and separation of trace bilirubin in real urine samples. Also, the recoveries for bilirubin in spiked biological samples (urine and serum) were found to be acceptable, between 95-102%. Conclusion: The proposed IL-DLLMEapproach was employed for the enrichment and determination of trace levels of bilirubin in urine samples using NaIO4 as an oxidizing agent and Uv-vis spectrophotometric detection. The periodate oxidation of bilirubin is rapid, effective, selective, and simple to perform. The method contains only HCl, NaOI4, and an anionic surfactant. The method may be useful for economizing in the consumption of reagents in bilirubin determining. The IL-DLLMEmethod ensures a high yield and has a low toxicity no skin sensitization, no mutagenicity and no ecotoxicity in an aquatic environment since only very low quantities of an IL is required. For full-color formation, no any extra auxiliary reagents are required. Besides, the IL-DLLME technique uses a low-cost instrument such as Uv-vis which is present in most of the medical laboratories.

Sign in / Sign up

Export Citation Format

Share Document