Rectosigmoid vaginoplasty in patients with vaginal agenesis: sexual and psychosocial outcomes

Sexual Health ◽  
2011 ◽  
Vol 8 (3) ◽  
pp. 427 ◽  
Author(s):  
Ljiljana D. Labus ◽  
Miroslav L. Djordjevic ◽  
Dusan S. Stanojevic ◽  
Marta R. Bizic ◽  
Borko Z. Stojanovic ◽  
...  
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Function ◽  
Psychosocial Adjustment ◽  
Severe Depression ◽  
Vaginal Agenesis ◽  
Symptoms Of Depression ◽  
High Satisfaction ◽  
Number Of Patients ◽  
The Right

Background The main goal in women with Mayer–Rokitansky–Küster–Hauser syndrome (vaginal agenesis) is creation of a neovagina that will satisfy the patient’s desire. We evaluated sexual and psychosocial adjustment in patients who underwent rectosigmoid vaginoplasty because of vaginal agenesis. Methods: A total of 36 women, aged 21 to 38 years (mean = 26) who underwent rectosigmoid vaginoplasty from 1997 to 2006 were evaluated. Sexual and psychosocial appraisal included the Female Sexual Function Index (FSFI), Beck’s Depression Inventory (BDI), and standardised questionnaires about postoperative satisfaction, social and sexual adjustment. Results: Mean FSFI score was 28.9 (range = 11.5–35.7) with a cut-off score of 26.55 for sexual dysfunction. Out of the 36 women, 10 (27, 8%) had sexual dysfunction. Mean BDI score was 7.55 (cut-off score = 0–9 for non-depression). Twenty-eight women (77.8%) were without symptoms of depression, six women (BDI range = 10–29) had moderate and two women had severe depression (BDI = 42). There were a significant number of patients (P < 0.01) with a high satisfaction score in FSFI and low BDI results. Thirty-two (88.9%) of the patients believed that surgery was done at the right time and the main postoperative support came from their family. Thirty-four (94.4%) of the patients reported satisfactory femininity, with a heterosexual orientation. Thirty patients (83. 3%) were very satisfied with the surgery, while 34 considered surgery as the best treatment. Conclusions: The sexual function and psychosocial status of these patients should be followed long-term to estimate their quality of life.

scholarly journals FRI0650-HPR SEXUAL DYSFUNCTION IN WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 929.2-929
Author(s):  
G. V. Espasa ◽  
L. Gonzalez Lucero ◽  
Y. Soria Curi ◽  
A. L. Barbaglia ◽  
S. M. Mazza ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Lupus Erythematosus ◽  
Severe Depression ◽  
Systemic Lupus ◽  
Depression Anxiety Stress Scale ◽  
Cross Sectional ◽  
Healthy Group ◽  
Healthy Women

Background:Sexual dysfunction is the alteration in one or several phases of sexual activity (desire, excitement, plateau, orgasm and resolution), which can culminate in frustration, pain and a decrease in the frequency of sexual intercourse. There are few studies that associate sexual dysfunction with Systemic Lupus Erythematosus (SLE) due to the difficulty in assessing it and its multifactorial cause.Objectives:Determine the frequency of sexual dysfunction and analyze associated factors in patients with SLE.Methods:A descriptive cross-sectional study was conducted. We included patients who attended the Rheumatology unit between May and July 2019; over 18 years of age, with a diagnosis of SLE according to the ACR 1997 and / or SLICC 2012 criteria, and healthy patients matched by age as control. Demographic and disease-related variables were studied. The DASS-21 (Depression Anxiety Stress Scale) scale that evaluates depression, anxiety and stress, and the Female Sexual Function Index (FSFI) that assesses 6 domains (desire, excitement, lubrication, orgasms, satisfaction and pain) were applied with a cut-off point ≤ 26.5 to define sexual dysfunction. Women over 50 years old, with secondary Sjogren’s syndrome, menopause, severe depression and illiterate patients were excluded.Results:One hundred and twenty three women were included (60 with SLE and 63 controls), with a mean age of 34.3 ± 8.3 and 31.7 ± 4.4 years respectively. The prevalence of sexual dysfunction in the SLE group was 71.7%; 95% CI = [58.5 – 82.5], and 23.8%, 95% CI = [13.9 – 36.2] in healthy patients. There were significant differences in all domains of sexual function between women with SLE and healthy group. In the desire, excitement and pain domains the differences were notable. The total FSFI score in patients with SLE was 18.2 ± 11.2 and in healthy women 28.3 ± 6.9 (p=0.001). Stress, anxiety and depression were observed in 58.4%, 58.3% and 50% of women with SLE and 19%, 20.6% and 28.5% of healthy women respectively (p=0.001). No association was found between sexual dysfunction and age, age at diagnosis, disease activity or treatment (pNS). No association was found in patients with SLE when analyzing the effect of sexual dysfunction in stress, depression and anxiety variables, in opposition to the healthy group (p<0.05).Conclusion:The prevalence of sexual dysfunction in patients with SLE was high (71.7%). Depression, Anxiety, and Stress were not decisive variables in Sexual Dysfunction.Disclosure of Interests:None declared

scholarly journals O Papel da Testosterona na Melhoria do Desejo Sexual da Mulher Pós-Menopáusica: Uma Revisão Baseada na Evidência

2018 ◽  
Vol 31 (11) ◽  
pp. 680
Author(s):  
Maria Gouveia ◽  
Raquel Sanches ◽  
Sara Andrade ◽  
Sara Carmona ◽  
Carolina Ferreira
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Function ◽  
Randomized Controlled Trials ◽  
Postmenopausal Women ◽  
Sexual Desire ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

Introduction: Female sexual dysfunction is a common problem, affecting more than 1/3 of women during their lives. The aim of this review is to review the evidence for the effectiveness of testosterone in sexual dysfunction in postmenopausal women, particularly in the improvement of sexual desire.Material and Methods: The authors searched in international databases National Guidelines Clearinghouse, Guidelines Finder, Cochrane Library and MEDLINE/PubMed, for guidelines, systematic reviews, meta-analysis and randomized controlled trials, published between January 2005 and February 2017, using the MeSH terms ‘testosterone’, ‘androgens’, ‘libido’, ‘sexual dysfunctions’ and ‘menopause’.Results: From a pool of 506 articles, 11 were selected: three guidelines, one systematic review with meta-analysis and seven randomized controlled trials. The selected articles showed testosterone‘s efficacy on global sexual function and improvement of sexual desire in postmenopausal women, when both are used in monotherapy or in association with other hormones. No study showed changes in hepatic enzymes or serious adverse effects.Discussion: The small sample size and short follow-up used in the included studies limits the ability to assess testosterone’s long-term benefits and effects.Conclusion: At short-term, testosterone seems to improve sexual function in postmenopausal women, particularly sexual desire. Nevertheless, more studies with larger sample size and longer follow-up are needed to understand its long-term safety and effectiveness.

scholarly journals Validating a Phenomenological Mathematical Model for Public Health and Safety Interventions Influencing the Evolutionary Stages of Recent Outbreak for Long-Term and Short-Term Domains in Pakistan

Complexity ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Ahsan Nawaz ◽  
Xing Su ◽  
Shahid Iqbal ◽  
Hafiz Zahoor ◽  
Ali Asad ◽  
...  
Keyword(s):  
Public Health ◽  
Health And Safety ◽  
Short Term ◽  
Number Of Patients ◽  
The World ◽  
Recent Outbreak ◽  
Safety Interventions ◽  
Containment Measures ◽  
The Right

During the outbreak of an epidemic, it becomes significantly essential to monitor the effects of containment measures and forecast the outbreak, including the epidemic peak. Many countries have either implemented strict lockdown to counter the spread of coronavirus disease or taken necessary preventive measures across the world to reduce the outbreak of this epidemic war. Several epidemic models have been presented across the world to examine the effects of public health-related strategies on mitigating the spread of current infectious disease, yet no reputable model has been presented for Pakistan as well as other South-Asian developing countries as per the authors’ knowledge. In this research, an actual coronavirus prediction in Pakistan is presented, which may guide the decision-makers as to how this pandemic has spread across the country and how it can be controlled. Furthermore, in the absence of targeted medicines, the analysis helps to develop a precise plan for the eradication of the outbreak by adopting the calculated steps at the right time. The mathematical phenomenological models have been adopted in this study to predict, project, and simulate the overall affected cases reflected due to the recent outbreak in Pakistan. These models predict the expected growth, and the estimated results are almost well matched with the real cases. Through the calibration of parameters and analyzing the current situation, forecast for the appearance of new cases in Pakistan is reported till the end of this year. The constant level of number of patients and time to reach specific levels are also reported through the simulations. The drastic conditions are also discussed which may occur if all the preventive restraints are removed. This research quantitatively describes the significant characteristics of the spread of corona cases. It acknowledges and provides an understanding of a short-term and long-term transmission of coronavirus outbreak in the country as three evolutionary phases. Therefore, this research provides a pathway to cope with the emerging threat of a severe outbreak in developing and nondeveloping countries.

scholarly journals The Impact of Depression on Patient Outcomes in Hip Arthroscopic Surgery

2018 ◽  
Vol 6 (11) ◽  
pp. 232596711880649 ◽  
Author(s):  
RobRoy L. Martin ◽  
John J. Christoforetti ◽  
Ryan McGovern ◽  
Benjamin R. Kivlan ◽  
Andrew B. Wolff ◽  
...  
Keyword(s):  
Rating Scale ◽  
Arthroscopic Surgery ◽  
Severe Depression ◽  
Outcome Data ◽  
Labral Repair ◽  
Initial Assessment ◽  
Symptoms Of Depression ◽  
Number Of Patients ◽  
The Impact

Background: Mental health impairments have been shown to negatively affect preoperative self-reported function in patients with various musculoskeletal disorders, including those with femoroacetabular impingement. Hypothesis: Those with symptoms of depression will have lower self-reported function, more pain, and less satisfaction on initial assessment and at 2-year follow-up than those without symptoms of depression. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who were enrolled in a multicenter hip arthroscopic surgery registry and had 2-year outcome data available were included in the study. Patients completed the 12-item International Hip Outcome Tool (iHOT-12), visual analog scale (VAS) for pain, and 12-item Short-Form Health Survey (SF-12) when consenting for surgery. At 2-year follow-up, patients were emailed the iHOT, the VAS, and a rating scale of surgical satisfaction. Initial SF-12 mental component summary (MCS) scores <46.5 and ≤36 were used to qualify symptoms of depression and severe depression, respectively, as previously described and validated. Repeated-measures analysis of variance was performed to compare preoperative and 2-year postoperative iHOT-12, VAS, and satisfaction scores between those with and without symptoms of depression. Results: A total of 781 patients achieved the approximate 2-year milestone (mean follow-up, 735 ± 68 days), with 651 (83%) having 2-year outcome data available. There were 434 (67%) female and 217 (33%) male patients, with a mean age of 35.8 ± 13.0 years and a mean body mass index of 25.4 ± 8.8 kg/m2. The most common procedures were femoroplasty (83%), followed by synovectomy (80%), labral repair (76%), acetabuloplasty (58%), acetabular chondroplasty (56%), femoral chondroplasty (23%), and labral reconstruction (19%). The mean initial SF-12 MCS score was 51.5 ± 10.3, with cutoff scores indicating symptoms of depression and severe depression in 181 (28%) and 71 (11%) patients, respectively. Patients with symptoms of depression scored significantly ( P < .05) lower on the initial iHOT-12 and VAS and 2-year follow-up iHOT-12, VAS, and rating scale of surgical satisfaction. Conclusion: A large number of patients who underwent hip arthroscopic surgery presented with symptoms of depression, which negatively affected self-reported function, pain levels, and satisfaction on initial assessment and at 2-year follow-up. Surgeons who perform hip arthroscopic surgery may need to identify the symptoms of depression and be aware of the impact that depression can have on surgical outcomes.

Long-Term Functional, Cosmetic and Sexual Outcomes of Hypospadias Correction Performed in Childhood

2015 ◽  
Vol 95 (2) ◽  
pp. 137-141 ◽  
Author(s):  
S. Thiry ◽  
T. Saussez ◽  
S. Dormeus ◽  
B. Tombal ◽  
F.X. Wese ◽  
...  
Keyword(s):  
Hypospadias Repair ◽  
Single Item ◽  
Mean Values ◽  
Sexual Outcomes ◽  
High Satisfaction ◽  
Number Of Patients ◽  
Overall Evaluation ◽  
Long Term Impact ◽  
Hypospadias Surgery

Objective: Hypospadias surgery, especially when performed early in life, may have a significant impact on the urinary and sexual functions in an adult. Because the literature is still limited, this paper assesses long-term functional, cosmetic and sexual results of hypospadias repair performed in childhood. Patients and Methods: The study includes 275 patients older than 12 years treated for a hypospadias by an Onlay, Mathieu, Duplay, or Duckett's technique between January 1990 and December 2000. Flowmetry results were retrospectively obtained from patients' charts. The Paediatric Penile Perception Score (PPPS), the Hypospadias Objective Scoring Evaluation (HOSE) and the IIEF-5 score (when older than 16 years old) questionnaires were used to assess cosmetic and sexual results. The PPPS is designed to assess both penile self-perception with regard to meatus, glans, skin and general appearance. The HOSE is a five-point scoring system designed to allow an objective appraisal of the outcome of hypospadias repair, based on evaluating meatal location, meatal shape, urinary stream, straightness of erection, and the presence and complexity of any complicating urethral fistula. Results: Qmax were within age-adjusted references, independent of the surgical technique, with median (range) Qmax of 18.8 ml/s (range 3-45, n = 136). Patients expressed a high satisfaction for every single item of the penile perception scale (PPPS), with mean values between 2 (satisfied) and 3 (very satisfied). Eighty-two percent were satisfied or very satisfied of the overall evaluation of penile appearance. Eighty-one percent of patients had a normal erectile function (IIEF-5 >22; n = 35/43). Conclusions: Taking into account the limitation of a small number of patients resulting from a low 21% questionnaire's response rate, the results of this study align with previous reports from the literature and confirms that hypospadias repair using standard techniques results in acceptable functional, cosmetic and sexual outcomes. This study highlights the need of developing a set of standard approved outcomes assessments tools for evaluating the long-term impact of hypospadias repair performed in infancy.

scholarly journals The impact of non-urologic drugs on sexual function in men

2014 ◽  
Vol 86 (1) ◽  
pp. 50 ◽  
Author(s):  
Ferdinando Fusco ◽  
Marco Franco ◽  
Nicola Longo ◽  
Alessandro Palmieri ◽  
Vincenzo Mirone
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Function ◽  
Antihypertensive Drugs ◽  
Long Term Effects ◽  
Physiological Mechanisms ◽  
Single Drug ◽  
Drug Classes ◽  
Short And Long Term ◽  
The Impact

Sexual dysfunctions have commonly been reported as the resulting side effects of many drugs. To understand the impact of a single drug, the mechanism of action of the most commonly prescribed drugs and the physiological mechanisms of sexual function have to be taken into dual consideration. Psychotropic drugs (Antidepressants, Antipsychotics and Antiepileptic) in particular result in both short and long-term effects on sexual function. Antihypertensive drugs have also produced evidence certifying their role in determining sexual dysfunction. Patients affected with sexual dysfunction are often aged and assume several drugs and, while Iatrogenic sexual dysfunction is prevalent in men, urological drugs are not the only drugs to be held accountable. Many different drugs acting on different sites and with several mechanisms of action can induce sexual dysfunction. The drug classes involved are widely diffused and frequently assumed in combination therapies.

scholarly journals Patient-Reported Bladder, Bowel, and Sexual Function After Cauda Equina Syndrome Secondary to a Herniated Lumbar Intervertebral Disc

2020 ◽  
Vol 26 (4) ◽  
pp. 290-303
Author(s):  
Jordan Lam ◽  
Ruth-Mary deSouza ◽  
Jonathan Laycock ◽  
Duranka Perera ◽  
Charlotte Burford ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sexual Dysfunction ◽  
Intervertebral Disc ◽  
Sexual Function ◽  
Cauda Equina Syndrome ◽  
Cauda Equina ◽  
Bladder Function ◽  
Patient Reported

Background: Cauda equina syndrome (CES) is rare neurosurgical emergency requiring emergent surgical decompression to prevent bladder, bowel, and sexual dysfunction that can have significant impact on quality of life. There is a paucity of data relating to the prevalence of these long-term complications. Objective: The aim of this observational study was to evaluate the long-term prevalence of CES-related bladder, bowel, and sexual dysfunction and impact on quality of life to inform service provision. Methods: Participants were selected through coding of operative records of patients who underwent lumbar decompression for CES secondary to a herniated intervertebral disc at two large UK neurosurgical departments between 2011 and 2015 inclusive. A telephone-based survey including both validated and modified tools was used to collect data pertaining to bladder, bowel, and sexual function and impact on quality of life both before development of CES and at the time of the survey, at least 1 year postoperatively. Results: Of 135 patients contacted, 71 (42 male, 29 female) responded. Post-CES compared to pre-CES, there was higher prevalence and significant intrarespondent deterioration of bowel dysfunction, bladder dysfunction, perception of bladder function, sexual function, effect of back pain on sex life, and activities of daily living/quality of life (p &lt; .0001 for all). Significant differences in individual questions pre-CES versus post-CES were also found. Conclusion: We show high prevalence of long-term bowel, bladder, and sexual dysfunction post-CES, with functional and psychosocial consequences. Our results demonstrate the need for preoperative information and subsequent screening and long-term multidisciplinary support for these complications.

scholarly journals PENGARUH VASEKTOMI TERHADAP FUNGSI SEKSUAL PRIA

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Mir'atul Fitri ◽  
Benny Wantouw ◽  
Lydia Tendean
Keyword(s):  
Sexual Dysfunction ◽  
Elementary Education ◽  
Sexual Function ◽  
Drug Users ◽  
Univariate Analysis ◽  
Target Population ◽  
Cross Sectional ◽  
Male Sexual Function ◽  
Excessive Stress

Abstract: Vasectomy in the community are still poorly understood, such as vasectomy can affect sexual function (sexual dysfunction). The purpose of this study was to determine the effect of vasectomy on male sexual function and the mechanisms of sexual function in men due to vasectomy. This study is a cross sectional analytic survey with a target population of men who have vasectomy totaling 67 people selected by proportional sampling of Manado City BKKBN January to August 2012. Instruments in this study using the questionnaire International Index Erectile Function (IIEF), the analysis of the data in this study using univariate analysis and Mann Whitney Sub Menu 2 Independent simple (SPSS 20 for Windows). The results, the majority of respondents aged > 35 years were 63 people (94.03%), elementary education as many as 48 people (62.34%), earning Rp. 500,000 - Rp. 1.000.000 by 47 people (70.1%), having more than one child as many as 64 people (95.5%), vasectomy contraceptive users with better sexual function by 56 people (83.60%), significant results statistics between vasectomy contraceptive users who have comorbidities, consuming drugs and having stress with sexual function. Contraception has no effect on male sexual function and sexual dysfunction occurs due to men having comorbidities, smoking and excessive alkohol consuming in the long term, drug users, and have excessive stress. Keywords: Vasectomy, Sexual Function, Male.     ABSTRAK: Vasektomi dikalangan masyarakat masih kurang dipahami, seperti vasektomi dapat berdampak terhadap fungsi seksual (disfungsi seksual). Tujuan penelitian ini untuk mengetahui pengaruh vasektomi terhadap fungsi seksual pria dan mekanisme fungsi seksual pada pria akibat vasektomi. Penelitian ini bersifat survei analitik pendekatan cross sectional dengan populasi target pria yang telah divasektomi berjumlah 67 orang dipilih secara proporsional sampling dari data BKKBN Kota Manado Januari-Agustus 2012. Instrumen dalam penelitian ini menggunakan Kuesioner Indeks Fungsi Ereksi Internasional (IIEF), analisa data dalam penelitian ini menggunakan analisa univariat dan analisa Mann Whitney Sub Menu 2 Independent simple (SPSS 20 for Windows). Hasil penelitian didapatkan mayoritas responden usia >35 tahun sebanyak 63 orang (94,03%), berpendidikan SD sebanyak 48  orang (62,34%), berpenghasilan Rp. 500.000 – Rp. 1.000.000 sebanyak 47 orang (70,1%), memiliki anak lebih dari satu orang sebanyak 64 orang (95,5%), pengguna kontrasepsi vasektomi dengan fungsi seksual baik sebanyak 56 orang (83,60%), hasil yang bermakna secara statistik antara pengguna kontrasepsi vasektomi yang memiliki penyakit penyerta, mengkonsumsi narkoba dan mengalami stres dengan fungsi seksual. Kontrasepsi vasektomi tidak berpengaruh pada fungsi seksual pria dan disfungsi seksual terjadi diakibatkan oleh pria memiliki penyakit penyerta, merokok dan mengkonsumsi alhokol dalam jangka waktu panjang dan volume berlebihan, pengguna narkoba, dan memiliki stress berlebihan. Kata kunci: Vasektomi, Fungsi seksual, Pria.

scholarly journals Sexual Function and Depressive Symptoms in Middle-Aged Women with LongLasting Type 1 Diabetes – A Cross-Sectional Study

2021 ◽  
Vol 6 (2) ◽  
Keyword(s):  
Quality Of Life ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Clinical Care ◽  
Estrogen Therapy ◽  
Severe Depression ◽  
Middle Aged ◽  
Cross Sectional

Background & aim: Women and men with diabetes, type 1 (T1D) and type 2 (T2D) develop complications in small and large blood vessels as well as in nerve pathways over time. In men, erectile dysfunction is a well-documented complication. However, sexual dysfunction in women with different types of diabetes is less studied. Sexual dysfunction is associated with lowered health-related quality of life and depression. The aim of the study was to investigate self-reported sexual function and signs of depression in middle-aged women with long-lasting T1D. Methods: A cross-sectional questionnaire study including the Female Sexual Function Index (FSFI) and the Patient Health Questionnaire (PHQ-9) together with background questions was designed. The sample was women aged 45-66 with T1D for at least 15 years, identified from clinical medical records at four hospitals in southern Sweden. Descriptive statistical analysis of background factors, depression, and self-reported sexual dysfunction, as well as correlation and regression analysis, are presented. Results: A total of 212 women completed the questionnaire, mean age 54.1 (SD: 5.83), mean years with T1D 36.2 (SD: 11.42). Almost half of the women had sexual dysfunction (45.2%; FSFI < 26.55, max 36) and the mean full score was 23.73 (SD: 10.57). The FSFI domains are desire, arousal, lubrication, orgasm, satisfaction and pain. Symptoms of depression measured by PHQ-9 were reported by 39.8%. A low FSFI was significantly associated with severe depression (p<0.001). Conclusions: Problems with sexual dysfunction and depression in middle-aged women with long-lasting T1D are common and may be unreported unless addressed in clinical care. Nurses could start asking women about problems with lubrication and vaginal pain in relation to sexual activity. Lubricants or local estrogen therapy could prevent those problems. Routinely assessing depressive status is equally important in improving quality of life for women with T1D.

scholarly journals VAGINAL PLATELET-RICH PLASMA ADMINISTRATION TO IMPROVE FEMALE SEXUAL SATISFACTION

2021 ◽  
Vol 9 (07) ◽  
pp. 258-266
Author(s):  
Mostafa Abdulla Elsayed Mahmoud
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Function ◽  
Female Sexuality ◽  
Platelet Rich Plasma ◽  
Vaginal Wall ◽  
Anterior Vaginal Wall ◽  
Autologous Plasma ◽  
The Third ◽  
High Satisfaction ◽  
Orgasmic Disorder

Objective:To investigate the effect of platelet-rich plasma (PRP) injection to the lower one-third of the anterior vaginal wall on sexual function, orgasm, in women with sexual dysfunction by scoring with FSFI. Materials and Methods:Three sessions of PRP (platelet rich human autologous plasma) were administered to the anterior vaginal wall of fiftyfemale patients with sexual dysfunctiondiagnosed by FSFI scoring card obtained in JAM clinic in Benha city Egypt and orgasmic disorder. Female Sexual Function Index (FSFI) total score ≤26 orgasmic subdomain score ≤3.75 were considered having sexual dysfunction and recruited in the study. Results:Following the application of the PRP, the total FSFI score was observed as 27.7±4.5 and the total score was 26 and above in patients having sexual dysfunction (p<0.001). Orgasm subdomain scores were found as 2.2±1.2 before the PRP treatment and 4.4±1.06 at the third dose after (p<0.001). Conclusion:PRP administration to the distal anterior vaginal wall improved female sexuality with high satisfaction by using multiple sessions (three month).

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