Sexual function and dysfunction in older HIV-positive individuals

Sexual Health ◽  
2011 ◽  
Vol 8 (4) ◽  
pp. 502 ◽  
Author(s):  
Darren B. Russell
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Functioning ◽  
Hiv Transmission ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Organ Systems ◽  
The World ◽  
Risk Of Disease ◽  
Living With Hiv ◽  
Hiv Negative

With many parts of the world seeing an aging cohort of people living with HIV (PLHIV), it is becoming clear that some organ systems in these individuals are at a greater risk of disease. There are effects on sexual functioning in aging PLHIV, with many studies finding higher levels of sexual dysfunction in HIV-positive individuals compared with those who are HIV-negative. HIV itself, along with antiretroviral agents, may cause dysfunction. Treatment involves making an assessment of the dysfunction and using the usual methods available, although treatment may be complicated by hormonal deficiencies in HIV-positive individuals, along with the effects of antiretroviral therapy, and drug interactions involving such medications. Furthermore, the issue of HIV transmission needs to be addressed in those seeking treatment for sexual dysfunction.

The Bio/Necropolitics of ACTG 076: Lessons from Pregnant Women of Colour Living with HIV for Treatment for Prevention in the Twenty-first Century

Somatechnics ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 233-253
Author(s):  
Eli Manning
Keyword(s):  
Hiv Transmission ◽  
Ethical Dilemmas ◽  
Hiv Treatment ◽  
First Century ◽  
Hiv Positive ◽  
Treatment As Prevention ◽  
People Living With Hiv ◽  
Hiv Positive Women ◽  
Aids Clinical Trials ◽  
Living With Hiv

Since the pharmaceutical turn, using HIV treatment to prevent transmission is increasingly common. Treatment as Prevention®, or TasP, has relied on HIV treatment to prevent HIV transmission, targeting people living with HIV. However, TasP is predicated on troublesome heterosexist, classist, and racist medical practices borrowed from various times and spaces that enact biopolitical and necropolitical relations. This paper discusses the debate surrounding the first clinical trial that used HIV treatment to prevent transmission from woman-to-foetus. The 1994 landmark AIDS Clinical Trials Group 076 study laid the groundwork for using HIV treatment to prevent HIV transmission, the essential precursor to TasP. By examining the concerns of HIV positive women of colour and other AIDS activists, we are able to understand the ethical dilemmas and practical consequences that still haunt today's game-changing uses of HIV treatment for prevention and to see how biopolitics and necropolitics persist in TasP.

scholarly journals Exploring the Factors Considered by People Living with HIV and Their Partners during Preconception

2016 ◽  
Vol 16 (3) ◽  
pp. 239-246 ◽  
Author(s):  
V. Logan Kennedy ◽  
Micaela Collins ◽  
Mark H. Yudin ◽  
Lena Serghides ◽  
Sharon Walmsley ◽  
...  
Keyword(s):  
Logit Model ◽  
Hiv Transmission ◽  
Horizontal Transmission ◽  
People Living With Hiv ◽  
Relative Importance ◽  
Hiv Status ◽  
Ordered Logit Model ◽  
Living With Hiv ◽  
Shed Light ◽  
Hiv Negative

Data are lacking on factors that may impact conception-related decision-making among individuals living with HIV. This study’s aim was to shed light on these considerations. Participants were invited to complete a survey on preconception considerations. A rank-ordered logit model was fit to estimate the relative importance of listed consideration factors; the interaction of HIV status and the factors was assessed. Fifty-nine participants living with HIV and 18 partners (11 HIV-negative participants and 7 living with HIV) were included. Risk of vertical and horizontal HIV transmission and the effect of antiretroviral therapy on the fetus were the top considerations. However, individuals living with HIV prioritized vertical transmission, whereas HIV-negative participants prioritized horizontal transmission. Other factors of importance were probability of conception, stress of trying to conceive, cost associated with fertility clinics, and stigma associated with certain conception methods. This study builds our understanding of the preconception considerations for people living with HIV.

scholarly journals Loco-Regional Treatments for Hepatocellular Carcinoma in People Living with HIV

2022 ◽  
Vol 14 (1) ◽  
pp. 43-55
Author(s):  
Cristina Micali ◽  
Ylenia Russotto ◽  
Grazia Caci ◽  
Manuela Ceccarelli ◽  
Andrea Marino ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Overall Survival ◽  
Cancer Staging ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Liver Cancers ◽  
Significant Difference ◽  
Cancer Specific Mortality ◽  
Living With Hiv ◽  
Hiv Negative

Hepatocellular carcinoma (HCC) accounts for approximately 75–90% of primary liver cancers and is the sixth most common cancer and the third leading cause of cancer-related deaths worldwide. In the HIV-positive population, the risk of HCC is approximately four times higher than in the general population, with higher cancer-specific mortality than in HIV-negative patients. In most cases, HCC diagnosis is made in patients younger than the HIV-negative population and in the intermediate-advanced stage, thus limiting the therapeutic possibilities. Treatment choice in HIV-positive patients with HCC is subject to cancer staging, liver function and health status, as for HIV-negative and non-HIV-negative HCC patients. There are relatively few studies on the efficacy and safety in HIV-positive patients to date in loco-regional treatments for HCC. So far, literature shows that curative treatments such as radiofrequency ablation (RFA) have no significant differences in overall survival between HIV-positive and HIV-negative patients, as opposed to palliative treatments such as TACE, where there is a significant difference in overall survival. Although it can be assumed that the most recently discovered loco-regional therapies are applicable to HIV-positive patients with HCC in the same way as HIV-negative patients, further studies are needed to confirm this hypothesis. The purpose of our review is to evaluate these treatments, their efficacy, effectiveness, safety and their applicability to HIV-positive patients.

scholarly journals Law, Criminalisation and HIV in the World: Have countries that criminalise achieved more or less successful AIDS pandemic response?

2021 ◽  
Author(s):  
Matthew M Kavanagh ◽  
Schadrac C Agbla ◽  
Mara Pillinger ◽  
Marissa Joy ◽  
Alaina Case ◽  
...  
Keyword(s):  
Drug Use ◽  
Sex Work ◽  
Viral Suppression ◽  
Hiv Transmission ◽  
People Living With Hiv ◽  
Gender Based Violence ◽  
Same Sex ◽  
The World ◽  
Laws And Policies ◽  
Living With Hiv

How does the use of criminal law affect disease-fighting efforts, particularly in a pandemic? This longstanding question for governments around the world is felt acutely in the context of the COVID-19 and HIV pandemics. Many countries have laws and policies that criminalise behaviours, making same-sex relationships, illicit drug use, and sex work illegal. Meanwhile, some countries have enshrined gender- and rights-protective institutions in law. Under the global AIDS strategy of the last five years, national AIDS response efforts in countries have focused on reaching people living with HIV with testing and antiretroviral treatment to suppress the HIV virus, preventing mortality and HIV transmission. At the end of this 5-year push, this article provides an ecological analysis of whether those countries with criminalising legal environments achieved more or less success. In countries where same-sex relationships were fully criminalised, the portion of people living with HIV who knew their status was 11% lower and viral suppression rates were 8% lower. Under sex-work criminalization, the rate of people living with HIV who knew their status was 10% lower and viral suppression 6% lower. Drug use criminalisation was associated with 14% lower knowledge of status and viral. On the other hand in countries with laws advancing non-discrimination, human rights institutions, and gender-based violence response, HIV services indicators were significantly better. This ecological evidence on the relationships between the legal environment and successful HIV response provides support for a strategy that includes a focus on law reform to achieve goals missed in 2020.

scholarly journals Studi Literatur: Hubungan Pengetahuan dengan Stigma pada Penderita HIV/AIDS (ODHA)

2021 ◽  
Vol 7 (1) ◽  
pp. 21
Author(s):  
Nila Alfiani ◽  
Ahmad Rido'i Yuda Prayogi ◽  
Ayik Mirayanti Mandagi ◽  
Diansanto Prayoga
Keyword(s):  
Systematic Review ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Systematic Review Methods ◽  
Hiv Virus ◽  
The World ◽  
Living With Hiv ◽  
The Relationship ◽  
Prevention Of Hiv ◽  
Hiv Aids

HIV/AIDS is a disease that has become a pandemic and worries people all over the world, because until now there has not been found a vaccine or drug for the prevention of HIV/AIDS. HIV positive cases in Indonesia from year to year have increased. The problems faced by people with HIV/AIDS are very complex. Every day the patient's condition will get weaker if he does not take medication regularly because the HIV virus will attack the patient's immune system. In addition, the stigma and discrimination of the surrounding community are also a burden that must be borne by people with HIV AIDS. The stigma makes HIV sufferers worse, with this stigma, HIV sufferers are ashamed to seek treatment at a health service. This writing is to determine the relationship between knowledge and stigma against people living with HIV/AIDS (PLWHA) through a review of various literature with the same theme. The method used in this paper uses rivew literature. This type of research uses systematic review. The study design used retrospective, prospective and systematic review methods. There is a relationship between knowledge and stigma against PLWHA. People with low knowledge tend to stigmatize people with HIV.

scholarly journals Law, criminalisation and HIV in the world: have countries that criminalise achieved more or less successful pandemic response?

2021 ◽  
Vol 6 (8) ◽  
pp. e006315
Author(s):  
Matthew M Kavanagh ◽  
Schadrac C Agbla ◽  
Marissa Joy ◽  
Kashish Aneja ◽  
Mara Pillinger ◽  
...  
Keyword(s):  
Viral Suppression ◽  
Hiv Transmission ◽  
People Living With Hiv ◽  
Hiv Status ◽  
Gender Based Violence ◽  
Hiv Virus ◽  
The World ◽  
Gender Based ◽  
And Gender ◽  
Living With Hiv

How do choices in criminal law and rights protections affect disease-fighting efforts? This long-standing question facing governments around the world is acute in the context of pandemics like HIV and COVID-19. The Global AIDS Strategy of the last 5 years sought to prevent mortality and HIV transmission in part through ensuring people living with HIV (PLHIV) knew their HIV status and could suppress the HIV virus through antiretroviral treatment. This article presents a cross-national ecological analysis of the relative success of national AIDS responses under this strategy, where laws were characterised by more or less criminalisation and with varying rights protections. In countries where same-sex sexual acts were criminalised, the portion of PLHIV who knew their HIV status was 11% lower and viral suppression levels 8% lower. Sex work criminalisation was associated with 10% lower knowledge of status and 6% lower viral suppression. Drug use criminalisation was associated with 14% lower levels of both. Criminalising all three of these areas was associated with approximately 18%–24% worse outcomes. Meanwhile, national laws on non-discrimination, independent human rights institutions and gender-based violence were associated with significantly higher knowledge of HIV status and higher viral suppression among PLHIV. Since most countries did not achieve 2020 HIV goals, this ecological evidence suggests that law reform may be an important tool in speeding momentum to halt the pandemic.

scholarly journals STIGMAS AND PREJUDICES EXPERIENCED BY PEOPLE LIVING WITH HIV/AIDS

2021 ◽  
Vol 9 (9) ◽  
pp. 616-633
Author(s):  
Kayo Elmano Costa da Ponte Galvão ◽  
Luciano da Silva Façanha ◽  
Roseane Lustosa de Santana Lira ◽  
Rivaldo Lira Filho ◽  
Raylene Frazão Lindoso Lindoso ◽  
...  
Keyword(s):  
Social Life ◽  
Critical Analysis ◽  
Public Health Problem ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Major Barrier ◽  
Physical Problems ◽  
The World ◽  
Living With Hiv ◽  
Hiv Aids

HIV is considered a public health problem in the world, especially in Brazil, where about 194,000 people have been infected with the virus in the last 10 years in the country. In addition to the physical problems that HIV infection imposes on HIV-positive individuals, social and institutional problems end up being a major barrier in the lives of these individuals, such as stigma and prejudice, which segregate and exclude them from social life. Objective: to make a critical analysis of the stigma and prejudice seen by people living with HIV in recent decades. Methodology: integrative literature review, with searches in lilacs, Bdenf and Scielo databases, based on the question "how prejudice interferes in the routine of people living with HIV/AIDS, and the stigmas that are carried by them". Eighteen (18) articles were selected in the respective databases, which followed the theme "HIV and prejudice". Results: Soon after the analysis of the articles, 03 thematic axes were constructed that helped to understand the data. Conclusion: It was noticed that prejudice and stigma are factors that transform, in a negative way, the life of those who have HIV/AIDS infection.

scholarly journals Electrocardiographic and echocardiographic abnormalities in urban African people living with HIV in South Africa

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0244742
Author(s):  
Geert V. T. Roozen ◽  
Ruchika Meel ◽  
Joyce Peper ◽  
William D. F. Venter ◽  
Roos E. Barth ◽  
...  
Keyword(s):  
South Africa ◽  
Viral Load ◽  
Left Ventricular Mass ◽  
Qt Interval ◽  
Left Ventricular ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Living With Hiv ◽  
Negative Controls ◽  
Hiv Negative

Background Studies from high income countries report that HIV-positive people have an impaired systolic and diastolic cardiac function compared to HIV-negative people. It is unclear if results can be translated directly to the Sub-Saharan Africa context. This study assesses electro- and echocardiographic characteristics in an urban African population, comparing HIV-positive people (treated and not yet treated) with HIV-negative controls. Methods We conducted a cross-sectional study in Johannesburg, South Africa. We enrolled HIV-positive participants from three randomized controlled trials that had recruited participants from routine HIV testing programs. HIV-negative controls were recruited from the community. Data were collected on demographics, cardiovascular risk factors, medical history and electrocardiographic and echocardiographic characteristics. Results In total, 394 HIV-positive participants and 153 controls were enrolled. The mean age of HIV-positive participants was 40±9 years (controls: 35±10 years), and 34% were male (controls: 50%). Of HIV-positive participants 36% were overweight or obese (controls: 44%), 23% had hypertension (controls: 28%) and 12% were current smoker (controls: 37%). Median time since HIV diagnosis was 6.0 years (IQR 2.3–10.0) and median treatment duration was 4.0 years (IQR 0.0–8.0), 50% had undetectable viral load. The frequency of anatomical cardiac abnormalities was low and did not differ between people with and without HIV. We observed no relation between HIV or anti-retroviral therapy (ART) and systolic or diastolic heart function. There was an association between ART use and corrected QT interval: +11.8 ms compared to HIV-negative controls (p<0.01) and +18.9 ms compared to ART-naïve participants (p = 0.01). We also observed a higher left ventricular mass index in participants on ART (+7.8 g/m2, p<0.01), but this association disappeared after adjusting for CD4 cell count, viral load and HIV-duration. Conclusion The low number of major cardiac abnormalities in this relatively young, well managed urban African HIV-positive population is reassuring. The increase in corrected QT interval and left ventricular mass may contribute to higher cardiac mortality and morbidity in people living with HIV in the long term.

scholarly journals The Impact of Migration on HIV Infection Situation (Analytical Review)

2019 ◽  
Vol 74 (2) ◽  
pp. 88-97
Author(s):  
Anastasia V. Pokrovskaya ◽  
Valeriy V. Yumaguzin ◽  
Dmitry E. Kireev ◽  
Maria V. Vinnik ◽  
Vadim V. Pokrovskiy
Keyword(s):  
Hiv Infection ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Negative Effects ◽  
State Budget ◽  
Global Epidemic ◽  
Legal Norms ◽  
The World ◽  
Living With Hiv ◽  
The Impact

Today, the unstable political and economic situation in the world has led to an intensified migration and changes in their directions. The legal norms regarding the status of migrants, including people living with HIV, are also changing. Over the past 10 years laws restricting the entry and residence of HIV-infected foreign citizens have been repealed in many countries, but in Russia the deportation and prohibition of long-term stay of HIV positive international migrants are still in effect. This review presents the main aspects of the impact of migration on the spread of HIV in the world and Russia, as well as the possible positive and negative effects of decriminalization of migrants living with HIV in terms of epidemic situation, socio-demographic and economic processes. The argument for retaining the deportation is due to the potential risk of the spread of the disease by foreigners and the unresolved organization of medical care and treatment of HIV infection for foreign migrants, which are provided for Russian citizens from the state budget. On the other hand, the deportation law touches upon ethical aspects, violating freedom of movement, the right to privacy and freedom from discrimination. Despite the presence or absence of restrictive measures against HIV-positive migrants, HIV has spread throughout all countries and led to a global epidemic. Prevention of HIV infection among general population of the country, regardless of their migration status, is a priority on the way to stop the spread of infection. 

scholarly journals Understanding stigma and coping strategies among HIV-negative Muslim wives in serodiscordant relationships in a Javanese community, Indonesia

2021 ◽  
Author(s):  
Yeni Lufiana Novita Agnes ◽  
Praneed Songwathana
Keyword(s):  
Coping Strategies ◽  
Peer Group ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Research Technology ◽  
Related Stigma ◽  
And Coping ◽  
Living With Hiv ◽  
Hiv Negative ◽  
Hiv Aids

Background: Although advanced treatment and accessibility of HIV/AIDS prevention and care have been increased, HIV-related stigma persists in the Indonesian community, especially among HIV-negative Muslim wives in a serodiscordant relationship. Therefore, understanding their coping strategies of the stigma is a necessity. Objective: The study aimed to explore HIV-related stigma and coping strategies of HIV-negative Muslim wives in a serodiscordant relationship. Methods: A qualitative study was conducted among seven HIV-negative Muslim wives in a serodiscordant relationship who experienced stigma.  Data were collected by in-depth interview, and content analysis was used for data analysis. Findings: Three themes emerged from the data. The first theme was the meaning of HIV/AIDS to Muslim wives, including perceiving HIV as a wanita nakal (immoral women) disease, perceiving HIV causes death, assuming herself as a carrier, and presuming HIV is less harmful than Diabetes Mellitus. The second theme was HIV-related stigma experiences, including being shunned by people, rejected by a midwife, and humiliated by a health worker. Finally, the third theme was coping strategies with the stigma, consisting of hiding the husband's HIV-positive status from the neighbors, disclosing HIV-positive status to a selective person, seeking support from the peer group, and strengthening the relationship among family members. Conclusion: HIV/AIDS-related stigma affected people living with HIV/AIDS and their families, and it becomes a barrier to HIV/AIDS reduction programs in the marriage relationship. These findings will be beneficial to nurses and other health professionals to develop stigma reduction interventions related to HIV/AIDS.   Funding: This research was funded by the Graduate School at Prince of Songkla University, Thailand; Kadiri University, Indonesia; and the Ministry of Research, Technology and Higher Education of Indonesia Scholarship.

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