scholarly journals Extraterrestrial ribose and other sugars in primitive meteorites

2019 ◽  
Vol 116 (49) ◽  
pp. 24440-24445 ◽  
Author(s):  
Yoshihiro Furukawa ◽  
Yoshito Chikaraishi ◽  
Naohiko Ohkouchi ◽  
Nanako O. Ogawa ◽  
Daniel P. Glavin ◽  
...  
Keyword(s):  
Stable Carbon Isotope ◽  
Building Blocks ◽  
Laboratory Simulation ◽  
Early Earth ◽  
Before And After ◽  
Show Evidence ◽  
Extraterrestrial Origin ◽  
Catalyzed Reactions ◽  
Stored Information ◽  
Life On Earth

Sugars are essential molecules for all terrestrial biota working in many biological processes. Ribose is particularly essential as a building block of RNA, which could have both stored information and catalyzed reactions in primitive life on Earth. Meteorites contain a number of organic compounds including key building blocks of life, i.e., amino acids, nucleobases, and phosphate. An amino acid has also been identified in a cometary sample. However, the presence of extraterrestrial bioimportant sugars remains unclear. We analyzed sugars in 3 carbonaceous chondrites and show evidence of extraterrestrial ribose and other bioessential sugars in primitive meteorites. The 13C-enriched stable carbon isotope compositions (δ13C vs.VPDB) of the detected sugars show that the sugars are of extraterrestrial origin. We also conducted a laboratory simulation experiment of a potential sugar formation reaction in space. The compositions of pentoses in meteorites and the composition of the products of the laboratory simulation suggest that meteoritic sugars were formed by formose-like processes. The mineral compositions of these meteorites further suggest the formation of these sugars both before and after the accretion of their parent asteroids. Meteorites were carriers of prebiotic organic molecules to the early Earth; thus, the detection of extraterrestrial sugars in meteorites establishes the existence of natural geological routes to make and preserve them as well as raising the possibility that extraterrestrial sugars contributed to forming functional biopolymers like RNA on the early Earth or other primitive worlds.

scholarly journals Computer Modeling of Barrel-Vaulted Sanctuary Exhibiting Flutter Echo with Comparison to Measurements

Acoustics ◽  
2020 ◽  
Vol 2 (1) ◽  
pp. 87-109
Author(s):  
Heather Lai ◽  
Brian Hamilton
Keyword(s):  
Computer Modeling ◽  
Architectural Design ◽  
Impulse Responses ◽  
Time Frequency ◽  
Geometrical Acoustics ◽  
Decay Times ◽  
Before And After ◽  
Show Evidence ◽  
Architectural Planning ◽  
The Cost

Computer modeling in acoustics allows for the prediction of acoustical defects and the evaluation of potential remediations. In this article, computer modeling is applied to the case of a barrel-vaulted sanctuary whose architectural design and construction led to severe flutter echoes along the main aisle, which was later mitigated through acoustical remediations. State-of-the-art geometrical acoustics and wave-based simulations are carried out to analyze the acoustics of this space, with a particular focus on the flutter echoes along the main aisle, before and after remediations. Multi-resolution wavelet and spectrogram analyses are carried out to isolate and characterize flutter echoes within measurements and computer-simulated room impulse responses. Comparisons of simulated responses to measurements are also made in terms of decay times and curves. Simulated room impulse responses from both geometrical acoustics and wave-based methods show evidence of flutter echoes matching measurements, to varying degrees. Time-frequency analyses isolating flutter echoes demonstrate better matches to measurements from wave-based simulated responses, at the cost of longer simulation times than geometrical acoustics simulations. This case study highlights the importance of computer modeling of acoustics in early design phases of architectural planning of worship spaces.

scholarly journals The formation of the building blocks of peptides on interstellar dust grains

2019 ◽  
Vol 15 (S350) ◽  
pp. 216-219
Author(s):  
N. F. W. Ligterink ◽  
J. Terwisscha van Scheltinga ◽  
V. Kofman ◽  
V. Taquet ◽  
S. Cazaux ◽  
...  
Keyword(s):  
Interstellar Dust ◽  
Reaction Network ◽  
Building Blocks ◽  
Dust Grains ◽  
Reaction Products ◽  
Experimental Conditions ◽  
Interstellar Dust Grains ◽  
Temperature Programmed ◽  
Life On Earth ◽  
Emergence Of Life

AbstractThe emergence of life on Earth may have its origin in organic molecules formed in the interstellar medium. Molecules with amide and isocyanate groups resemble structures found in peptides and nucleobases and are necessary for their formation. Their formation is expected to take place in the solid state, on icy dust grains, and is studied here by far-UV irradiating a CH4:HNCO mixture at 20 K in the laboratory. Reaction products are detected by means of infrared spectroscopy and temperature programmed desorption - mass spectrometry. Various simple amides and isocyanates are formed, showing the importance of ice chemistry for their interstellar formation. Constrained by experimental conditions, a reaction network is derived, showing possible formation pathways of these species under interstellar conditions.

scholarly journals High expression of VRT2 during wheat spikelet initiation increases the number of rudimentary basal spikelets

2021 ◽  
Author(s):  
Anna E Backhaus ◽  
Ashleigh Lister ◽  
Melissa Tomkins ◽  
Nikolai M. Adamski ◽  
James Simmonds ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Profiles ◽  
Computational Modelling ◽  
Gene Expression Profiles ◽  
Building Blocks ◽  
Field Trials ◽  
Developmental Genetics ◽  
Spatially Resolved ◽  
Before And After ◽  
Single Spike

Spikelets are the fundamental building blocks of Poaceae inflorescences and their development and branching patterns determine the various inflorescence architectures and grain yield of grasses. In wheat, the central spikelets produce the most and largest grains, while spikelet size gradually decreases acro- and basipetally, giving rise to the characteristic lanceolate shape of wheat spikes. The acropetal gradient correlates with the developmental age of spikelets, however the basal spikelets are developed first and the cause of their small size and rudimentary development is unclear. Here, we adapted G&T-seq, a low-input transcriptomics approach, to characterise gene expression profiles within spatial sections of individual spikes before and after the establishment of the lanceolate shape. We observed larger differences in gene expression profiles between the apical, central and basal sections of a single spike than between any section belonging to consecutive developmental timepoints. We found that SVP MADS-box transcription factors, including VRT-A2, are expressed highest in the basal section of the wheat spike and display the opposite expression gradient to flowering E-class SEP1 genes. Based on multi-year field trials and transgenic lines we show that higher expression of VRT-A2 in the basal sections of the spike is associated with increased numbers of rudimentary basal spikelets. Our results, supported by computational modelling, suggest that the delayed transition of basal spikelets from vegetative to floral developmental programmes results in the lanceolate shape of wheat spikes. This study highlights the value of spatially resolved transcriptomics to gain new insights into developmental genetics pathways of grass inflorescences.

scholarly journals Teaching biological evolution - internal and external evaluation of learning outcomes

2012 ◽  
Vol 5 (2) ◽  
pp. 171-184
Author(s):  
Clas Olander
Keyword(s):  
Biological Evolution ◽  
National Sample ◽  
External Evaluation ◽  
Process Data ◽  
Theory Of Evolution ◽  
Before And After ◽  
Teaching Learning ◽  
Life On Earth ◽  
Evaluation Of Learning ◽  
Experimental Group

This paper reports from a study where teachers and researchers collaborate on designing and validatingtopic-oriented teaching-learning sequences. In an iterative process, data about learning andteaching biological evolution are generated through continuous cycles of design, teaching, evaluation,and redesign. The study involved 180 Swedish students aged 11 – 16, and the overall learning aim was that the students should be able to use the theory of evolution as a tool when explaining the development of life on earth. The aim of this paper is to validate the students’ learning outcome, estimated as appropriation of scientific ways of reasoning in written answers. The students’ answers of questions are analysed before and after interventions (internal evaluation), and compared with the answers from a national sample (external evaluation). The students in the experimental group did develop their reasoning, and they attained the aim, to a greater extent than a national sample.

scholarly journals Safety Impacts of Converting Two-Way Left-Turn Lanes to Raised Medians and Associated Design Concerns

2016 ◽  
Author(s):  
Priyanka Alluri ◽  
Albert Gan ◽  
Kirolos Haleem
Keyword(s):  
Data Availability ◽  
Left Turn ◽  
Arterial Streets ◽  
Crash Data ◽  
Potential Safety ◽  
Before And After ◽  
Show Evidence ◽  
Crash Types ◽  
Associated Design ◽  
Urban Arterial

Raised medians and two-way left-turn lanes (TWLTLs) are the two most common types of median treatments on arterial streets. This paper aims to conduct a detailed study on the safety impacts of conversion from TWLTLs to raised medians on state roads in Florida. In addition, the study also investigated several potential safety concerns related to raised medians on state roads, including crashes at median openings, vehicles directly hitting the median curb, and median crossover crashes. Based on data availability, 17.51 miles of urban arterial sections in Florida that were converted from TWLTLs to raised medians were analyzed. Police reports of all the crashes before and after median conversion were reviewed to correct miscoded crash types and obtain additional detailed crash information. Overall, a 28.5% reduction in total crash rate was observed after the 10 study locations were converted from TWLTLs to raised medians. The reductions in the proportions of left-turn and right-turn crashes were statistically significant, while the changes in the proportions of other crash types were not statistically significant. Furthermore, the crash data did not show evidence that raised medians are an additional hazard compared with TWLTLs.

Laboratory simulation of UV irradiation from the Sun on amino acids. I: irradiation of tyrosine

2007 ◽  
Vol 6 (2) ◽  
pp. 123-129 ◽  
Author(s):  
F. Scappini ◽  
F. Casadei ◽  
R. Zamboni ◽  
S. Monti ◽  
P. Giorgianni ◽  
...  
Keyword(s):  
Amino Acids ◽  
Uv Irradiation ◽  
Degradation Products ◽  
Building Blocks ◽  
Laboratory Simulation ◽  
The Sun ◽  
Primitive Earth ◽  
Laboratory Results ◽  
Building Capability ◽  
Primordial Life

AbstractThe effects of ultraviolet (UV) irradiation on water solutions of tyrosine (HO—C6H4—CH2—CHNH2—COOH) have been investigated using a Xe lamp in the region 200–800 nm. This is a step in laboratory simulation towards reproducing the action of the Solar radiation on the building blocks of life, specifically α-amino acids, in the primitive Earth anoxic conditions. Results are presented showing the photostability of tyrosine against different UV doses. Degradation products partly maintain life building capability and partly do not. A tendency towards structure complexification was observed. The analysis of the irradiated tyrosine solutions was conducted using various spectroscopic and analytic techniques. The laboratory results are discussed in the light of a primordial life-emerging scenario.

Chemical evolution toward the origin of life

2007 ◽  
Vol 79 (12) ◽  
pp. 2101-2117 ◽  
Author(s):  
Daniel Fitz ◽  
Hannes Reiner ◽  
Bernd Michael Rode
Keyword(s):  
Chemical Evolution ◽  
Rna World ◽  
Early Stage ◽  
Building Blocks ◽  
Point Of View ◽  
Peptide Formation ◽  
The Origin Of Life ◽  
Life On Earth ◽  
Primordial Earth ◽  
Rna And Dna

Numerous hypotheses about how life on earth could have started can be found in the literature. In this article, we give an overview about the most widespread ones and try to point out which of them might have occurred on the primordial earth with highest probability from a chemical point of view. The idea that a very early stage of life was the "RNA world" encounters crucial problems concerning the formation of its building blocks and their stability in a prebiotic environment. Instead, it seems much more likely that a "peptide world" originated first and that RNA and DNA took up their part at a much later stage. It is shown that amino acids and peptides can be easily formed in a realistic primordial scenario and that these biomolecules can start chemical evolution without the help of RNA. The origin of biohomochirality seems strongly related to the most probable formation of the first peptides via the salt-induced peptide formation (SIPF) reaction.

scholarly journals Swansong biospheres II: the final signs of life on terrestrial planets near the end of their habitable lifetimes

2014 ◽  
Vol 13 (3) ◽  
pp. 229-243 ◽  
Author(s):  
Jack T. O'Malley-James ◽  
Charles S. Cockell ◽  
Jane S. Greaves ◽  
John A. Raven
Keyword(s):  
Environmental Conditions ◽  
Late Stage ◽  
Cloud Cover ◽  
Main Sequence ◽  
Interaction Model ◽  
Early Earth ◽  
Sequence Evolution ◽  
The Sun ◽  
Upper Limit ◽  
Life On Earth

AbstractThe biosignatures of life on Earth do not remain static, but change considerably over the planet's habitable lifetime. Earth's future biosphere, much like that of the early Earth, will consist of predominantly unicellular microorganisms due to the increased hostility of environmental conditions caused by the Sun as it enters the late stage of its main sequence evolution. Building on previous work, the productivity of the biosphere is evaluated during different stages of biosphere decline between 1 and 2.8 Gyr from present. A simple atmosphere–biosphere interaction model is used to estimate the atmospheric biomarker gas abundances at each stage and to assess the likelihood of remotely detecting the presence of life in low-productivity, microbial biospheres, putting an upper limit on the lifetime of Earth's remotely detectable biosignatures. Other potential biosignatures such as leaf reflectance and cloud cover are discussed.

scholarly journals Circular polarization signals of cloudy (exo)planets

2018 ◽  
Vol 616 ◽  
pp. A117 ◽  
Author(s):  
L. Rossi ◽  
D. M. Stam
Keyword(s):  
Circular Polarization ◽  
Polarized Light ◽  
Building Blocks ◽  
Cloud Particle ◽  
Circularly Polarized Light ◽  
Particle Properties ◽  
Spatially Resolved ◽  
Life On Earth ◽  
Polarization Of Light ◽  
Phase Angles

Context. The circular polarization of light that planets reflect is often neglected because it is very small compared to the linear polarization. It could, however, provide information on a planet’s atmosphere and surface, and on the presence of life, because homochiral molecules that are the building blocks of life on Earth are known to reflect circularly polarized light. Aims. We compute Pc, the degree of circular polarization, of light that is reflected by rocky (exo)planets to provide insight into the viability of circular spectropolarimetry for characterizing (exo)planetary atmospheres. Methods. We compute the Pc of light that is reflected by rocky (exo)planets with liquid water or sulfuric acid solution clouds, both spatially resolved across the planetary disk and, for planets with patchy clouds, integrated across the planetary disk, for various planetary phase angles α. Results. The optical thickness and vertical distribution of the atmospheric gas and clouds, the size parameter and refractive index of the cloud particles, and α all influence Pc. Spatially resolved, Pc varies between ± 0.20% (the sign indicates the polarization direction). Only for small gas optical thicknesses above the clouds do significant sign changes (related to cloud particle properties) across the planets’ hemispheres occur. For patchy clouds, the disk-integrated Pc is typically smaller than ± 0.025%, with maximum for α between 40° and 70°, and 120° to 140°. As expected, the disk-integrated Pc is virtually zero at α = 0° and 180°. The disk-integrated Pc is also very small at α ≈ 100°. Conclusions. Measuring circular polarization signals appears to be challenging with current technology. The small atmospheric circular polarization signal could, however, allow the detection of circular polarization due to homochiral molecules such as those associated with life on Earth. Confirmation of the detectability of such signals requires better knowledge of the strength of circular polarization signals of biological sources and in particular of the angular distribution of their scattering.

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