scholarly journals Myocardial infarction risk in relation to zinc concentration in toenails

2003 ◽  
Vol 89 (5) ◽  
pp. 673-678 ◽  
Author(s):  
J. M. Martin-Moreno ◽  
L. Gorgojo ◽  
R. A. Riemersma ◽  
J. Gomez-Aracen ◽  
J. D. Kark ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Case Control Study ◽  
Epidemiological Studies ◽  
Case Control ◽  
Study Centre ◽  
First Myocardial Infarction ◽  
Control Study

Zn is an essential mineral. The role of Zn in atherosclerosis is not clear. Epidemiological studies, which have reported contradictory results, are limited by the use of serum Zn levels as a marker of intake. We assessed the association of toenail Zn, which integrates dietary Zn intake over 3 to 12 months, with the risk of a first myocardial infarction. Toenail Zn concentrations were determined by neutron activation analysis in the European multi-centre case–control study on antioxidants, myocardial infarction and breast cancer. This multi-centre case–control study included 684 cases and 724 controls from eight European countries and Israel. Toenail Zn levels of controls (adjusted for age and study centre) were positively associated with age, α-tocopherol and Se, but not with additional dietary variables or with classical risk factors for CHD. Average toenail Zn was 106·0 mg/kg in cases (95 % CI 103·1, 108·9) and 107·5 mg/kg in controls (95 % CI 104·5, 110·7). After controlling for cardiovascular risk factors and for centre, the adjusted odds ratios of myocardial infarction for quintiles 2–5 of toenail Zn with respect to the first quintile were 0·97 (95 % CI 0·59, 1·58), 1·15 (95 % CI 0·72, 1·85), 0·91 (95 % CI 0·56, 1·50), and 0·85 (95 % CI 0·52, 1·39). ThePfor trend was 0·45. In conclusion toenail Zn levels (reflecting long-term dietary intake) were not significantly associated with acute myocardial infarction.

scholarly journals Among the risk factors of myocardial infarction, anthropometry has no association: A case control study in the central region of Sri Lanka

2013 ◽  
Vol 03 (04) ◽  
pp. 1-5
Author(s):  
Pallegoda Vithanage Ranhith Kumarasiri ◽  
Senanayake Abesinghe Mudiyanselage Kularatne ◽  
Rohini Tennakoon ◽  
Nirmali Gunawardana ◽  
Usha Perera ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Sri Lanka ◽  
Central Region ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals 1434. Risk Factors for Community-Acquired Urinary Tract Infections Caused by Extended-Spectrum β-Lactamase (ESBL) Producing Escherichia coli in Children: A Case–Control Study

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S523-S524
Author(s):  
Frank Zhu ◽  
Rodado Maria ◽  
Basim Asmar ◽  
Hossein Salimnia ◽  
Ronald Thomas ◽  
...  
Keyword(s):  
Risk Factors ◽  
Escherichia Coli ◽  
Case Control Study ◽  
Case Control ◽  
Antibiotic Usage ◽  
Ethnic Background ◽  
E Coli ◽  
Tract Infections ◽  
Control Study

Abstract Background In recent years, there has been an increasing incidence of community-acquired urinary tract infections (UTI) caused by extended-spectrum β-lactamase (ESBL) producing Escherichia coli. However, the risk factors of ESBL-producing bacteria in community-acquired (CA)-UTI in children in the USA remain unclear. Methods A retrospective case–control study of UTI due to CA-ESBL-producing E. coli during a 5-year period (2011–2016) was performed. Control cases of non-ESBL-producing E. coli UTI were matched by age, gender, and year of infection. Medical records were manually reviewed to collect data for potential risk factors for ESBL-positive infection. Results A total of 111 patients with ESBL-producing E coli UTI and 103 control patients were included. The proportion of ESBL-producing E coli UTI ranged from 7% to 15% per year. The median age was 4 years with female predominance (84%). The ESBL group was predominantly African American (32%) followed by patients of Middle Eastern (ME) ethnic background (31%). Risk factors by univariate analysis were vesicoureteral reflux (VUR): (20.9 ESBL group vs. 6% controls; P = 0.002), prior antibiotic usage in the previous 3 months (including β-lactams), prior UTI (last 3 months), recent hospitalization (last 3 months) and ME ethnic background. However, multivariate analysis showed that only prior antibiotic usage (P = 0.001) and ME ethnic background (P < 0.001) remained statistically significant. 18% (11/60) of patients exposed to prior antibiotic use in the ESBL group were on long-term antibiotic prophylaxis for VUR. Conclusion Risk factors for CA-ESBL-producing E coli UTI in children were: (1) antibiotic usage within the previous 3 months and (2) ME background. Prior antibiotic usage as a risk factor reinforces the need for judicious use of antibiotics. The high percentage of patients in this group (18%) receiving long-term antibiotic prophylaxis for VUR warrants further study as this practice may increase the prevalence of ESBL-producing infections in a population at high risk for UTI. The increased risk among children of ME ethnic background warrants further study to evaluate possible additional associated risk factors such as recent international travel or contact with international travelers. Disclosures All authors: No reported disclosures.

Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors - a multicentre case-control study

2000 ◽  
Vol 111 (2) ◽  
pp. 534-539 ◽  
Author(s):  
Christine Heller ◽  
Rosemarie Schobess ◽  
Karin Kurnik ◽  
Ralf Junker ◽  
Gudrun Gunther ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thrombosis ◽  
Case Control Study ◽  
Case Control ◽  
Prothrombotic Risk Factors ◽  
Neonates And Infants ◽  
Control Study
Sign in / Sign up

Export Citation Format

Share Document