scholarly journals Reducing iron deficiency anaemia due to heavy menstrual blood loss in Nigerian rural adolescents

1998 ◽  
Vol 1 (4) ◽  
pp. 249-257 ◽  
Author(s):  
Fiona Barr ◽  
Loretta Brabin ◽  
Shola Agbaje ◽  
Fiekumo Buseri ◽  
John Ikimalo ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Transferrin Saturation ◽  
Menstrual Blood ◽  
Menstrual Disorders ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Deficiency Anaemia

AbstractObjective:Menstrual disorders are common in young women, and heavy menstrual blood losses (MBL) are an important cause of anaemia. Menstrual morbidity normally goes untreated in developing countries where cultural barriers also serve to mask the problems. We investigated the prevalence of menstrual morbidity, and measured MBL and its relationship to iron deficiency in a rural adolescent population. The rationale was to assess whether or not reducing heavy MBL could be part of a strategy to reduce iron deficiency anaemia.Setting:Rural village in south-east Nigeria.Design:Cross-sectional survey.Subjects:The study included all non-pregnant, unmarried nulliparous girls (< 20 years) who had menstruated, and who lived in K'Dere village.Methods:A field worker allocated to each girl completed a questionnaire, and supervised recovery and collection of soiled pads and ensured blood sampling. MBL was measured using the standard alkaline haematin method. Haemoglobin (Hb), serum iron, transferrin saturation and protoporphyrin levels (ZPP) were also measured.Results:307 girls completed MBL measurements; 11.9% refused to participate. 12.1% had menorrhagia (> 80 ml); median MBL was 33.1 ml. Menorrhagia was more frequent in girls who had menstruated for > 2 years (P = 0.048), and had longer duration of menses (P < 0.001). Iron status as measured by haematocrit, serum iron, transferrin saturation and ZPP values was inversely related to MBL. Neither height nor body mass index for age was associated with current iron status.Conclusions:The level of menorrhagia detected (12%) may be an ‘expected’ level for a condition which often has no underlying pathology. Heavy MBL is one of the most important factors contributing to iron deficiency anaemia. Measures are needed to alleviate menstrual disorders, and improve iron status. Oral contraceptives can be part of a strategy to reduce anaemia, particularly for adolescents at high risk of unwanted pregnancies.

scholarly journals Reducing iron deficiency anaemia due to heavy menstural blood loss in Nigerian rural adolescents. Reprinted from Public Health Nutrition Volume 1 (4), 249–257, 1998

2005 ◽  
Vol 8 (5) ◽  
pp. 451-460
Author(s):  
Fiona Barr ◽  
Loretta Brabin ◽  
Shola Agbaje ◽  
Feikumo Buseri ◽  
John Ikimalo ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Transferrin Saturation ◽  
Cultural Barriers ◽  
Menstrual Disorders ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Deficiency Anaemia

AbstractObjectiveMenstrual disorders are common in young women, and heavy menstrual blood losses (MBL) are an important cause of anaemia. Menstrual morbidity normally goes untreated in developing countries where cultural barriers also serve to make the problems. We investigated the prevelance of menstrual morbidity, and measured MBL and its relationship to iron deficiency in a rural adolescent population. The rationale was to assess whether or not reducing heavy MBL could be part of a strategy to reduce iron deficiency anaemia.SettingRural village in south-east Nigeria.DesignCross-sectional survey.SubjectsThe studdy included all non-pregnant, unmarried nulliparous girls (< 20 years) who had menstruated, and who lived in K'Dere village.MethodsA field worker allocated to each girl completed a questionnaire, and supervised recovery and collection of soiled pads and ensured blood sampling. MBL was measured using the standard alkaline haematin method. Haemoglobin (HB), serum iron, transferin saturation and protoporphyrin levels (ZPP) were also measured.Results307 girls completed MBL measurements; 11.9% refused to participate. 12.1% had menorrhagia (> 80 ml);. median MBL was 33.1 ml. Menorrhagia was more frequent in girls who had menstruated for > 2 years (p = 0.048), and had longer duration of meneses (p < 0.001). Iron status as measured by haematocrit, serum iron, transferrin saturation and ZPP values was inversely related to MBL. Neither height nor body mass index for age was associated with current iron status.ConclusionsThe level of menorrhagia detected (12%) may be an ‘expected’ level for a condition which often has no underlying pathology. Heavy MBL is one of the most important factors contributing to iron deficiency anaemia. Measures are needed to alleviate menstrual disorders and improve iron status. Oral contraceptives can be part of a strategy to reduce anaemia, particularly for adolescents at high risk of unwanted pregnancies.

scholarly journals Risk factors for iron-deficiency anaemia among pregnant women living in rural Vietnam

2006 ◽  
Vol 9 (4) ◽  
pp. 443-448 ◽  
Author(s):  
Ritsuko Aikawa ◽  
Ngyen C Khan ◽  
Satoshi Sasaki ◽  
Colin W Binns
Keyword(s):  
Risk Factors ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Western Medicine ◽  
Iron Deficiency Anaemia ◽  
Severe Anaemia ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Deficiency Anaemia ◽  
Hb Concentration

AbstractObjectiveTo assess the prevalence of anaemia in rural Vietnam and to determine its risk factors.DesignA cross-sectional survey.SettingVietnam, Nghe An Province.Study populationThe total number of participants was 439. Of these participants, one was excluded from the study due to a mental disorder. Forty-seven did not participate in the test for parasites and 68 did not complete at least one of the questions.ResultsThe prevalence of anaemia (haemoglobin (Hb) < 11.0 g dl−1) was 43.2% and of severe anaemia (Hb < 8.0 g dl−1) was 0.5%. Taking iron tablets, the consumption of eggs and the preference for Western medicine significantly and positively correlated with Hb concentration in the pregnant women in a multiple regression analysis. Pregnancy duration and hookworm infestation significantly and negatively correlated with Hb concentration in the pregnant women.ConclusionThe prevalence of anaemia in rural Vietnam has remained as high as that found in the national anaemia survey in 2000. The results of the present study could aid in the development of an iron-deficiency anaemia programme among pregnant women in rural Vietnam that emphasises iron supplementation, parasite control and improved diet, including the consumption of eggs. The programme's focus should be on women who prefer traditional medicine to Western medicine.

scholarly journals Burden of Helicobacter pylori Infections and Associated Risk Factors among Cases of Iron Deficiency Anaemia in Egypt

2020 ◽  
pp. 80-91
Author(s):  
Hadir M. El- Kady ◽  
Waiel Al- Kahiry ◽  
Hadeel Said Tawfik Abdelsalam
Keyword(s):  
Helicobacter Pylori ◽  
Iron Deficiency ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Binding Capacity ◽  
Public Health Problem ◽  
Occult Blood ◽  
Cross Sectional ◽  
Deficiency Anaemia ◽  
H Pylori

Introduction: Iron deficiency anaemia (IDA) is a worldwide nutritional problem; it accounts for about half of the world’s anaemia burden. Globally, Helicobacter pylori (H. pylori) is becoming an increasingly troublesome economic and public health problem. The colonization of the organism in gastric mucosa may impair iron uptake and increase iron loss, potentially leading to iron deficiency anaemia. The mechanisms by which H. pylori is postulated to cause IDA are H. pylori -associated chronic gastritis resulting in hypo/or achlorhydria, reduced ascorbic acid secretion and reduced intestinal iron absorption, occult blood loss due to chronic erosive gastritis, and sequestration and utilization of iron by Helicobacter pylori. Aims: To detect H. pylori–related IDA prevalence among asymptomatic cases of anaemia and to address the possibility that such infection may play a detrimental role in their blood picture, serum iron and ferritin levels and total iron binding capacity (TIBC) Study Design & Methods: Facility based cross-sectional study was conducted in the period from December 2018 to May 2019. Screening was done for asymptomatic attendants of a   number of private laboratories in Beheira, Alexandria and Gharbiya governorates. Three hundreds of whom were proved to be cases of IDA and were further tested for H. pylori antigen in stool. Results: Helicobacter pylori Ag test in stool was positive in 180 out of 300 cases of iron deficiency anaemia. The infection significantly affected the haemoglobin level, MCV, MCH and RDW in studied cases (p<0.05). Infection with H. pylori also significantly affected the serum iron, serum ferritin and TIBC in the studied cases of IDA (p<0.05). Conclusion: A significant association between H. pylori infection and IDA. Screening for H. pylori among unexplained cases of IDA is recommended.

scholarly journals Study on association of iron status in children with simple febrile seizure and without seizures

2018 ◽  
Vol 5 (4) ◽  
pp. 1300 ◽  
Author(s):  
Anantha Narayana Gowda B. L. ◽  
Praveen C. Samuel
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Complete Blood Count ◽  
Iron Status ◽  
Demographic Data ◽  
Venous Blood ◽  
Febrile Seizures ◽  
Laboratory Assessment ◽  
Cross Sectional ◽  
Deficiency Anaemia

Background: Considering the age prevalence of iron deficiency anaemia and febrile convulsion which are the same, the role of iron in the metabolism of neurotransmitters (such as GABA and serotonin) and some enzymes (such as monoaminoxidase and aldehideoxidase), the function of hemoglobin in conveying oxygen to the brain and since fever can exacerbate symptoms that result from anaemia, a relationship between iron deficiency anaemia and febrile convulsions is probable. Thus, the present study was conducted to determine the iron profile in children with simple febrile seizures and febrile children without seizures and also to find out the association between iron levels and simple febrile seizures.Methods: A cross sectional comparative study was conducted among the infants and children aged between 6 months to 6 years with complaints of fever with/ without seizures attending Pediatrics OPD, Sri Siddartha Medical College, Tumkur during the period between 2016 to 2018. Purposive sampling of equal number of children in two study groups were made. Demographic data, seizure details, nature of febrile illness, family history of epilepsy /febrile seizures, temperature at admission and nutritional status were recorded. For laboratory assessment, 2 ml venous blood was drawn and sent for estimation of complete blood count with peripheral smear. Statistical analysis was done using SPSS version 16.Results: Among 112 study participants, 60.7% were anaemic. The indicators of iron deficiency anaemia like Hb%, MCH, TIBC and S. ferritin were associated with febrile seizures and were statistically significant.Conclusions: Anaemia prevalence in infants and young children is high and was significantly associated with febrile seizures.

scholarly journals THE POTENTIAL OF RETICULOCYTE HAEMOGLOBIN EQUIVALENT (RET-HE) IN IRON DEFICIENCY ANAEMIA SCREENING AT BETHESDA HOSPITAL, YOGYAKARTA

2020 ◽  
Vol 5 (2) ◽  
pp. 60
Author(s):  
Fenty Fenty Fenty
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Cross Sectional Study ◽  
Future Research ◽  
Sectional Study ◽  
Cross Sectional ◽  
Deficiency Anaemia ◽  
High Risk Populations ◽  
Laboratory Record

Background: Traditionally, iron deficiency anaemia (IDA) is diagnosed with iron and ferritin status. Ret-He measurement is a promising parameter to detect iron depletion in earlier stages. Previous studies recommended Ret-He examination as IDA screening. Objective: Compare the Ret-He level and iron status of patients with and without IDA at Bethesda Hospital, Yogyakarta. Method: This is a cross-sectional study using laboratory record of haematological examination at Bethesda Hospital from march to August 2019. Erythrocyte indices, iron status and Ret-He measurement was further examined between IDA and non-IDA group by ANOVA, t-test or non-parametric tests. Results: There were 105 samples, where 22 (20.95%) had complete result of Ret-He and iron status, and 10 (45.45%) diagnosed with IDA. The Ret-He level in IDA group is significantly lower than non-IDA group (17.53 ± 2.43 vs 31.50 ± 4.03, p < 0.001). Conclusion: Ret-He level is lower in IDA group, consistent with other biochemical parameters (Serum iron, Serum ferritin, TIBC, and TSAT). This finding might lead to future research on the potential of Ret-He for early detection of IDA in high-risk populations.

scholarly journals The potential effect of iron defortification on iron-deficiency anaemia in the US population

2007 ◽  
Vol 10 (11) ◽  
pp. 1266-1273 ◽  
Author(s):  
Min Tao ◽  
David L Pelletier ◽  
Dennis D Miller
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Potential Effect ◽  
Reproductive Age ◽  
Iron Nutrition ◽  
Deficiency Anaemia ◽  
Adult Men ◽  
The Us ◽  
The Usa

AbstractObjectiveTo quantify the potential effect of iron defortification in the USA on iron-deficiency anaemia (IDA).MethodsMonte Carlo models were built to simulate iron nutrition in the US population. A hypothetical cohort of 15 000 persons from the general population was used in 15-year simulations to compare the prevalence of IDA with and without fortification.ResultsWith iron fortification, the prevalence of IDA was 2.4% for children aged 3–5 years, 5.4% for women aged 20–49 years, and 0.14% for men aged 20–49 years. The corresponding IDA estimates under iron defortification were 4.5%, 8.2% and 0.46%, respectively. Defortification had little effect on the distribution of iron indicators at or above the 50th percentile within each of these three groups and little effect on the distributions of iron indicators among adult men.ConclusionIron defortification is likely to increase IDA among children and women of reproductive age, but is not likely to have meaningful effects on the iron status of men or the majority of women and children.

scholarly journals A study to assess the effectiveness of honey dates amla mix on biochemical markers among adolescent girls with Iron deficiency anaemia

2020 ◽  
Vol 11 (2) ◽  
pp. 2288-2293
Author(s):  
Bhuvaneswari G.
Keyword(s):  
Iron Deficiency ◽  
Adolescent Girls ◽  
Biochemical Markers ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Control Group ◽  
Deficiency Anaemia ◽  
Post Test ◽  
And Control ◽  
Experimental Group

WHO Global Database on Anaemia for 1993-2005, covering almost half of the world’s population, estimated the prevalence of anaemia worldwide at 25 per cent.The aim of the study is to determine the effectiveness of honey dates amla mix on biochemical markers among adolescent girls with Iron deficiency anaemia. Quantitative experimental and control group pre and post-test design was used in this study. The study was conducted among adolescent girls in two different residential homes. Total study population is 170 adolescent girls were selected by simple random sampling technique. 85 adolescents girls were assigned to the experimental group and 85 participants in control group. For experimental group honey dates amla mix was given for 3 months whereas in  the control group iron and folic acid supplementation were provided. The study results shows that pre and post-test intervention scores of control and experimental group were compared by Wilcoxon scores rank test. Comparison of pre-test and post-test scores of severity of anemia, clinical variables, and level of fatigue and level of satisfaction, bio chemical parameters (reticulocytes, MCV, haematocrite, serum iron, serum ferritin, TIBC) were assessed in both experimental and control group. Between the experimental and control group (unpaired‘t’ test) reticulocytes, mcv, heamatocrite, serum iron serum ferritin showed significant changes in the pre test and post-test but there is no changes in TIBC. The study concluded that alternative nutritional therapy was effective for enhancing the blood heamoglobin & biochemical paramteres level, decreased the clinical variables and fatigue level among the adolescent girls with iron deficiency anemia.

scholarly journals Impact of Iron Status on Thyroid Function: A Community Based Cross-Sectional Study in Eastern Nepal

2019 ◽  
Vol 15 (1) ◽  
pp. 18-21 ◽  
Author(s):  
Saroj Thapa ◽  
Madhab Lamsal ◽  
Sanjay Kumar Sah ◽  
Rajendra Kumar Chaudhari ◽  
Basanta Gelal ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Status ◽  
Transferrin Saturation ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Hormone Profile ◽  
Iron Deficient ◽  
The Mean

Background: Iron deficiency is the most common nutritional deficiency in the world. The relation between thyroid hormones and iron status is bidirectional. The aim of this study was to assess iron nutrition status and evaluate its relationship with thyroid hormone profile among children of Eastern Nepal. Methods: A  community based cross-sectional study was conducted in eastern Nepal. A total of 200 school children aged 6-12 years were recruited after taking informed consent from their guardians. Blood samples were collected and assayed for free thyroid hormones (fT3 and fT4), thyroid stimulating hormone (TSH), serum iron, total iron binding capacity (TIBC) concentration and percentage transferrin saturation was calculated. Results: The mean serum iron and TIBC was 74.04 µg/dl and 389.38 µg/dl respectively. The median transferring saturation was 19.21%. The overall prevalence of iron deficiency (Transferrin saturation < 16%) was 34% (n=68). The mean concentration of fT3 and fT4 was 2.87 pg/ml and 1.21 ng/dl respectively, while the median TSH concentration was 3.03 mIU/L. Median TSH concentration in iron deficient group (3.11 µg/dl) and iron sufficient group (2.91 µg/dl) was not significantly different. Among iron deficient children 5.9% had   subclinical hypothyroidism (n=4). Iron status indicators were not significantly correlated with thyroid profile parameters in the study population. Conclusions: The prevalence of iron deficiency is high and iron   deficiency does not significantly alter the thyroid hormone profile in the study region.

MENSTRUAL BLOOD-LOSS IN IRON-DEFICIENCY ANÆMIA

The Lancet ◽  
1965 ◽  
Vol 286 (7409) ◽  
pp. 407-409 ◽  
Author(s):  
A. Jacobs ◽  
E.Blanche Butler
Keyword(s):  
Iron Deficiency ◽  
Blood Loss ◽  
Iron Deficiency Anaemia ◽  
Menstrual Blood ◽  
Menstrual Blood Loss ◽  
Deficiency Anaemia
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