Risk factors associated with back pain in New Zealand school children

AimsWe set out to identify risk factors for progression in untreated keratoconus patients from 34 centres across Australia, New Zealand, Spain and Italy.MethodsPatients were divided into ‘progressors’ and ‘stable’ patients for each clinical parameter: visual acuity (VA), steepest keratometry (maximum keratometry (Max-K)) and thinnest corneal thickness (TCT). Primary outcomes were the proportion of eyes with sustained progression in VA, Max-K or TCT within 3 years. Secondary outcomes included predictors of progression.ResultsThere were 3994 untreated eyes from 2283 patients. The proportion of eyes with VA, Max-K and TCT progression at 1 year were 3.2%, 6.6% and 3.1% respectively. Factors associated with VA loss were higher baseline VA (HR 1.15 per logMAR line increase in VA; p<0.001) and steeper baseline Max-K (HR 1.07 per 1D increase; p<0.001). Younger baseline age was associated with Max-K steepening (HR 0.96 per year older; p=0.001). Thicker baseline TCT, steeper baseline Max-K and younger baseline age were associated with TCT thinning: (HR 1.08 per 10 µm increase in TCT; p<0.001), (HR 1.03 per 1D increase; p=0.02) and (HR 0.98 per year younger; p=0.01), respectively.ConclusionsSteeper Max-K and younger age were the most clinically useful baseline predictors of progression as they were associated with worsening of two clinical parameters. Every 1D steeper Max-K was associated with a 7% and 3% greater risk of worsening VA and thinning TCT, respectively. Each 1 year younger was associated with a 4% and 2% greater risk of steepening Max-K and thinning TCT, respectively.

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Risk Factors Associated with Work-Related Low Back Pain Among Home-Based Garment Workers

Advances in Intelligent Systems and Computing - Intelligent Human Systems Integration 2020 ◽

10.1007/978-3-030-39512-4_115 ◽

2020 ◽

pp. 753-759

Author(s):

Sunisa Chaiklieng ◽

Pornnapa Suggaravetsiri ◽

Sari Andajani

Keyword(s):

Risk Factors ◽

Low Back Pain ◽

Back Pain ◽

Low Back ◽

Factors Associated ◽

Work Related ◽

Garment Workers ◽

Home Based

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Prevalence and Risk Factors Associated with Upper Limb Disorders and Low Back Pain Among Informal Workers of Hand-Operated Rebar Benders

Human Systems Engineering and Design II - Advances in Intelligent Systems and Computing ◽

10.1007/978-3-030-27928-8_93 ◽

2019 ◽

pp. 611-618

Author(s):

Sunisa Chaiklieng ◽

Pornnapa Suggaravetsiri ◽

Wiwat Sungkhabut ◽

Jenny Stewart

Keyword(s):

Risk Factors ◽

Low Back Pain ◽

Back Pain ◽

Upper Limb ◽

Low Back ◽

Informal Workers ◽

Factors Associated ◽

Upper Limb Disorders

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Risk factors associated with acquiring superficial fungal infections in school children in South Western Nigeria: a comparative study

African Health Sciences ◽

10.4314/ahs.v17i2.6 ◽

2017 ◽

Vol 17 (2) ◽

pp. 330 ◽

Cited By ~ 1

Author(s):

Olaide Oke Olutoyin ◽

Olaniyi Onayemi ◽

Akinlolu Omisore Gabriel

Keyword(s):

Risk Factors ◽

Comparative Study ◽

School Children ◽

Fungal Infections ◽

Factors Associated

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Factors associated with disabling low back pain among nursing personnel at a medical centre in Japan: a comparative cross-sectional survey

BMJ Open ◽

10.1136/bmjopen-2019-032297 ◽

2019 ◽

Vol 9 (9) ◽

pp. e032297 ◽

Cited By ~ 3

Author(s):

Takahiko Yoshimoto ◽

Hiroyuki Oka ◽

Shuhei Ishikawa ◽

Akatsuki Kokaze ◽

Shingo Muranaga ◽

...

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Low Back Pain ◽

Back Pain ◽

Nursing Personnel ◽

Low Back ◽

Cross Sectional ◽

Previous Episode ◽

Factors Associated ◽

Self Administered Questionnaire

ObjectivesLow back pain (LBP) is a common cause of disability among nursing personnel. Although many studies regarding the risk factors for LBP among nursing staff have focused on the physical load at work, multidimensional assessments of risk factors are essential to identify appropriate preventive strategies. We aimed to investigate the association of multidimensional factors (individual, physical, psychological and occupational) with disabling LBP among nursing personnel in Japan.DesignObservational study with comparative cross-sectional design.SettingData were collected using the self-administered questionnaire at a tertiary medical centre.ParticipantsAfter excluding participants with missing variables, 718 nursing personnel were included in the analysis.Outcome measuresA self-administered questionnaire assessed individual characteristics, rotating night shift data, severity of LBP, previous episode of LBP, sleep problem, kinesiophobia (Tampa Scale for Kinesiophobia), depressive condition (K6), physical flexibility and frequency of lifting at work. A logistic regression model was used to evaluate the factors associated with disabling LBP (LBP interfering with work) among nursing personnel.ResultsOf all participants, 110 (15.3%) reported having disabling LBP. The multivariable logistic regression analysis after adjustment for several confounding factors showed that kinesiophobia (highest tertile, adjusted OR (aOR): 6.13, 95% CI : 3.34 to 11.27), previous episode of LBP (aOR: 4.31, 95% CI: 1.50 to 12.41) and insomnia (aOR: 1.66, 95% CI: 1.05 to 2.62) were significantly associated with disabling LBP.ConclusionsThe present study indicated that kinesiophobia, a previous episode of LBP, and sleep problems were associated with disabling LBP among nursing personnel. In the future, workplace interventions considering assessments of these factors may reduce the incidence of disabling LBP in nursing staff, although further prospective studies are needed.

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‘BRCA1’ RESPONSIVENESS TOWARDS BREAST CANCER-A POPULATION-WISE PHARMACOGENOMIC ANALYSIS

International Journal of Pharmacy and Pharmaceutical Sciences ◽

10.22159/ijpps.2016.v8i9.13457 ◽

2016 ◽

Vol 8 (9) ◽

pp. 267 ◽

Cited By ~ 2

Author(s):

Preethi M. Iyer ◽

Sanjay Kumar P. ◽

Karthikeyan S. ◽

P. K Krishnan Namboori

Keyword(s):

Breast Cancer ◽

Risk Factors ◽

New Zealand ◽

Environmental Factors ◽

Chromosome 17 ◽

Base Pairs ◽

Single Nucleotide ◽

Factors Associated ◽

Variation Database ◽

Different Populations

Objective: In the present pharmacogenomic work, the genetic, epigenetic and environmental factors associated with BRCA1 induced breast cancer, cancer proneness and its variants across different populations like Indian, Netherland, Belgium, Denmark, Austrian, New Zealand, Sweden, Malaysian and Norwegian and the ‘mutation and methylation-prone’ region of BRCA1 have been computed.Methods: The global variations associated with the disease have been identified from the ‘Leiden open variation database (LOVD 3.0)’ and ‘Indian genome variation database (IGVDB)’. The variants, ‘single nucleotide polymorphisms (SNPs)’ are then characterized. The epigenetic factors associated with breast cancer have been identified from the clinical reports and further scrutinized using EpiGRAPH tool. The various contributing environmental factors responsible for the variations have been considered.Results: All the variants across different populations such as Indian, Netherland, Belgium, Denmark, Austrian, New Zealand, Sweden, Malaysian and Norwegian are found to be in a specific transcript of BRCA1 that ranges within 41,196,312-41,277,500 (81,189 base pairs) of the chromosome 17. Two ‘single nucleotide variations (SNVs)’ (5266dupC: rs397507246 and 68_69delAG: rs386833395) have been identified as risk factors in hereditary breast and ovarian cancer syndrome in the global population and 39 SNPs have been identified as pathogenic and deleterious. ‘Evolutionary history’ seems to be the most significant attribute in the predictability of methylation of BRCA1. Unhealthy dietary habits, obesity, use of unsafe cosmetics, estrogen exposure, ‘hormone replacement therapy (HRT)’, use of oral contraceptives and smoking are the major environmental risk factors associated with breast cancer incidence.Conclusion: This chromosome location (41,196,312-41,277,500 (81,189 base pairs)) can be considered as the population-specific sensitive region corresponding to BRCA1 mutation. This supports the fact that stabilization within the region can be a promising technique to control the epigenetic variants associated with the global position. The global variation in the proneness of the disease may be due to a cumulative effect of genetic, epigenetic and environmental factors subject to further experimentations with identical variations and populations.

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Trunk Lateral Flexor Endurance and Body Fat: Predictive Risk Factors for Low Back Pain in Child Equestrian Athletes

Children ◽

10.3390/children7100172 ◽

2020 ◽

Vol 7 (10) ◽

pp. 172

Author(s):

Antonio Cejudo ◽

Angélica Ginés-Díaz ◽

Olga Rodríguez-Ferrán ◽

Fernando Santonja-Medina ◽

Pilar Sainz de Baranda

Keyword(s):

Risk Factors ◽

Low Back Pain ◽

Back Pain ◽

Body Fat ◽

Lower Limb ◽

Musculoskeletal Injury ◽

Low Back ◽

Factors Associated ◽

Potential Risk Factors ◽

Predictive Risk

Low back pain (LBP) is the most common overuse musculoskeletal injury suffered by child equestrian athletes (CEA). Despite this, little is known about the risk factors related to LBP in these athletes, and very limited research has been conducted on this topic. This study was designed to investigate predictive risk factors for LBP in CEA. The purposes of this research were to determine whether anthropometric, range of motion (ROM), core endurance and sagittal spinal morphotype measures are risk factors for LBP and to establish a diagnostic cutoff value for those factors associated with LBP. Nineteen CEA between the ages of 12 and 17 years were voluntarily recruited. Potential risk factors evaluated included corporal composition, lower limb ROM, core endurance and sagittal spinal measures. Associations and predictions were calculated between these risk factors and the LBP during the last 12 months. Almost half of the CEA have suffered at least one episode of LBP. Two risk factors and cutoff values were identified as predictors of LBP in CEA: having a high body fat higher than 23% (p = 0.01) and trunk lateral flexor endurance lower to 65 s (p = 0.021), body fat being the strongest predictor.

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