The Association between Parental Attachment and Youth Suicidal Ideation: A Three-Level Meta-analysis

2021 ◽  
pp. 1-26
Author(s):  
Huan Yang ◽  
Guangming Ran ◽  
Qi Zhang ◽  
Xiang Niu
Keyword(s):  
Suicidal Ideation ◽  
Parental Attachment ◽  
Meta Analysis

scholarly journals Efficacy of dialectical behavior therapy for adolescent self-harm and suicidal ideation: a systematic review and meta-analysis

2021 ◽  
pp. 1-11
Author(s):  
Oswald D. Kothgassner ◽  
Andreas Goreis ◽  
Kealagh Robinson ◽  
Mercedes M. Huscsava ◽  
Christian Schmahl ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Suicidal Ideation ◽  
Dialectical Behavior Therapy ◽  
Meta Analysis ◽  
Adolescent Psychopathology ◽  
Cochrane Library ◽  
Behaviour Therapy ◽  
Clinical Consequences ◽  
Self Harm

Abstract Background Given the widespread nature and clinical consequences of self-harm and suicidal ideation among adolescents, establishing the efficacy of developmentally appropriate treatments that reduce both self-harm and suicidal ideation in the context of broader adolescent psychopathology is critical. Methods We conducted a systematic review and meta-analysis of the Dialectical Behaviour Therapy for Adolescents (DBT-A) literature on treating self-injury in adolescents (12–19 years). We searched for eligible trials and treatment evaluations published prior to July 2020 in MEDLINE/PubMed, Scopus, Google Scholar, EMBASE, and the Cochrane Library databases for clinical trials. Twenty-one studies were identified [five randomized-controlled trials (RCTs), three controlled clinical trials (CCTs), and 13 pre-post evaluations]. We extracted data for predefined primary (self-harm, suicidal ideation) and secondary outcomes (borderline personality symptoms; BPD) and calculated treatment effects for RCTs/CCTs and pre-post evaluations. This meta-analysis was pre-registered with OSF: osf.io/v83e7. Results Overall, the studies comprised 1673 adolescents. Compared to control groups, DBT-A showed small to moderate effects for reducing self-harm (g = −0.44; 95% CI −0.81 to −0.07) and suicidal ideation (g = −0.31, 95% CI −0.52 to −0.09). Pre-post evaluations suggested large effects for all outcomes (self-harm: g = −0.98, 95% CI −1.15 to −0.81; suicidal ideation: g = −1.16, 95% CI −1.51 to −0.80; BPD symptoms: g = −0.97, 95% CI −1.31 to −0.63). Conclusions DBT-A appears to be a valuable treatment in reducing both adolescent self-harm and suicidal ideation. However, evidence that DBT-A reduces BPD symptoms was only found in pre-post evaluations.

scholarly journals Rates and risk factors for suicidal ideation, suicide attempts and suicide deaths in persons with HIV: a systematic review and meta-analysis

2021 ◽  
Vol 34 (2) ◽  
pp. e100247
Author(s):  
Matt Pelton ◽  
Matt Ciarletta ◽  
Holly Wisnousky ◽  
Nicholas Lazzara ◽  
Monica Manglani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Suicidal Ideation ◽  
General Population ◽  
Suicide Attempts ◽  
Advanced Disease ◽  
Meta Analysis ◽  
People Living With Hiv ◽  
Meta Regression ◽  
Living With Hiv

BackgroundPeople living with HIV/AIDS (PLWHA) must contend with a significant burden of disease. However, current studies of this demographic have yielded wide variations in the incidence of suicidality (defined as suicidal ideation, suicide attempt and suicide deaths).AimsThis systematic review and meta-analysis aimed to assess the lifetime incidence and prevalence of suicidality in PLWHA.MethodsPublications were identified from PubMed (MEDLINE), SCOPUS, OVID (MEDLINE), Joanna Briggs Institute EBP and Cochrane Library databases (from inception to before 1 February 2020). The search strategy included a combination of Medical Subject Headings associated with suicide and HIV. Researchers independently screened records, extracted outcome measures and assessed study quality. Data were pooled using a random-effects model. Subgroup and meta-regression analyses were conducted to explore the associated risk factors and to identify the sources of heterogeneity. Main outcomes were lifetime incidence of suicide completion and lifetime incidence and prevalence of suicidal ideation and suicide attempt.ResultsA total of 185 199 PLWHA were identified from 40 studies (12 cohorts, 27 cross-sectional and 1 nested case-control). The overall incidence of suicide completion in PLWHA was 10.2/1000 persons (95%CI: 4.5 to 23.1), translating to 100-fold higher suicide deaths than the global general population rate of 0.11/1000 persons. The lifetime prevalence of suicide attempts was 158.3/1000 persons (95%CI: 106.9 to 228.2) and of suicidal ideation was 228.3/1000 persons (95%CI: 150.8 to 330.1). Meta-regression revealed that for every 10-percentage point increase in the proportion of people living with HIV with advanced disease (AIDS), the risk of suicide completion increased by 34 per 1000 persons. The quality of evidence by Grading of Recommendations, Assessment, Development and Evaluations for the suicide deaths was graded as ‘moderate’ quality.ConclusionsThe risk of suicide death is 100-fold higher in people living with HIV than in the general population. Lifetime incidence of suicidal ideation and attempts are substantially high. Suicide risk assessments should be a priority in PLWHA, especially for those with more advanced disease.

scholarly journals Suicidality: Once Again, Don’t Blame the Drug Class

2021 ◽  
pp. 153575972110531
Author(s):  
Faught Edward
Keyword(s):  
Clinical Trials ◽  
Suicidal Ideation ◽  
Risk Ratio ◽  
Randomized Clinical Trials ◽  
Rating Scale ◽  
Meta Analysis ◽  
Adjunctive Treatment ◽  
Current Evidence ◽  
Phase 2 ◽  
Increased Risk

Importance Mostantiseizure medications (ASMs) carry a US Food and Drug Administration–mandated class label warning of increased suicidality risk, based on a meta-analysis comparing suicidality between individuals treated with medications vs placebo in randomized clinical trials done before 2008. ASMs approved since then carry this warning although they were not similarly studied. Objective To review all placebo-controlled phase 2 and 3 studies of 10 ASMs approved since 2008 to evaluate the risk of suicidality of these drugs compared with placebo. Data Sources Primary publications and secondary safety analyses in PubMed of all phase 2 and 3 randomized placebo-controlled epilepsy trials of ASMs approved since 2008, using keywords epilepsy, antiepileptic drugs, seizures, suicidality, suicidal ideation, and the names of individual drugs. Study Selection All phase 2 and 3 randomized clinical trials of adjunctive treatment of drug-resistant epilepsy and their secondary safety analyses. Data Extraction and Synthesis Articles were reviewed for frequency of suicidality (ideation, attempts, and completed suicides). Mode of suicidality ascertainment included treatment-emergent adverse event reports, Standardized Medical Dictionary for Regulatory Activities queries for events in prespecified categories including suicidal ideation and behavior, prospective collection of suicidality data as a prespecified safety outcome using the Columbia-Suicide Severity Rating Scale, and retrospective evaluation by blinded review using the Columbia-Classification Algorithm of Suicide Assessment. A meta-analysis compared risk for drugs vs placebo of each outcome for all drugs overall and by individual drugs and trials. Main Outcomes and Measures Suicidality (total and by ideation), attempts, and completed suicides. Results Excluding studies that did not evaluate suicidality (everolimus and fenfluramine) or did not evaluate it prospectively (lacosamide, ezogabine, and clobazam), 5 drugs were analyzed: eslicarbazepine, perampanel, brivaracetam, cannabidiol, and cenobamate. Suicidality was evaluated in 17 randomized clinical trials of these drugs, involving 5996 patients, of whom 4000 patients were treated with ASMs and 1996 with placebo. There was no evidence of increased risk of suicidal ideation (drugs vs placebo overall risk ratio, .75; 95% CI, .35–1.60) or attempt (risk ratio, .75; 95% CI, .30–1.87) overall or for any individual drug. Suicidal ideation occurred in 12 of 4000 patients treated with ASMs (.30%) vs 7 of 1996 patients treated with placebo (.35%) ( P  =  .74). Three patients treated with ASMs and no patients treated with placebo attempted suicide ( P  =  .22). There were no completed suicides. Conclusions and Relevance There is no current evidence that the 5 ASMs evaluated in this study increase suicidality in epilepsy and merit a suicidality class warning

scholarly journals Prevalence of Suicidal Ideation and Suicide Attempts Among Refugees: A Meta-analysis

2021 ◽  
Author(s):  
Elisa Haase ◽  
Antje Schönfelder ◽  
Yuriy Nesterko ◽  
Heide Glaesmer
Keyword(s):  
Suicidal Ideation ◽  
Stressful Life Events ◽  
Suicide Attempts ◽  
Mental Health Problems ◽  
Economic Status ◽  
Meta Analysis ◽  
High Risk Group ◽  
Prevalence Rates ◽  
Psychological Burden ◽  
Period Prevalence

Abstract Background: Suicidal ideation and attempts are one of the most serious mental health problems affecting refugees. Risk factors such as mental disorders, low socio-economic status, and stressful life events all contribute to making refugees a high-risk group. For this reason, this meta-analysis aims to investigate the prevalence of suicidal ideation and attempts among refugees in non-clinical populations.Method: All studies published in English up through August 2020 were considered for the analysis. We searched four databases for articles reporting (period) prevalence rates of suicidal ideation and attempts. Results: Of 294 hits, 11 publications met the inclusion criteria. Overall prevalence rates were calculated using Rstudio. The overall period prevalence of suicidal ideation was 20.5% (CI: 0.11-0.32, I²=98%, n=8), 22.3% (CI: 0.10-0.38, I²=97%, n=5) for women, and 23.3% for men (CI: 0.13-0.35, I²=87%, n=3). Suicide attempts had an overall prevalence of 0.57% (CI: 0.00-0.02, I²=81%, n=4). Conclusion: There is a great lack of epidemiological studies on suicidal ideation and attempts among refugees. The high prevalence of suicidal ideation indicates the existence of heavy psychological burden among this population. The prevalence of suicide attempts is similar to that in non-refugee populations. In addition, the results underline the need for systematic and standardized assessment and treatment of suicidal ideation and attempts.

scholarly journals Prevalence of suicidal behavior in young university students: A systematic review with meta-analysis

2021 ◽  
Vol 29 ◽  
Author(s):  
Marília de Oliveira Crispim ◽  
Cândida Maria Rodrigues dos Santos ◽  
Iracema da Silva Frazão ◽  
Cecília Maria Farias de Queiroz Frazão ◽  
Rossana Carla Rameh de Albuquerque ◽  
...  
Keyword(s):  
Systematic Review ◽  
Suicidal Ideation ◽  
University Students ◽  
Suicidal Behavior ◽  
Attempted Suicide ◽  
Data Extraction ◽  
Meta Analysis ◽  
Cross Sectional ◽  
High Prevalence ◽  
Theses And Dissertations

Objective: to identify the prevalence of suicidal behavior in young university students. Method: a systematic review with meta-analysis of cross-sectional studies based on the Joanna Briggs Institute proposal, and carried out in the PubMed, Web of Science, Scopus, PsycINFO and LILACS databases and in the Brazilian Digital Library of Theses and Dissertations, with no language or year restrictions. A total of 2,942 publications were identified. Selection, data extraction and methodological evaluation of the studies were performed by two independent researchers. The meta-analysis was performed considering the random effects model. Results: eleven articles were included in this review. The prevalence variation for suicidal ideation was from 9.7% to 58.3% and, for attempted suicide, it was from 0.7% to 14.7%. The meta-analysis showed a 27.1% prevalence for suicidal ideation in life, 14.1% for ideation in the last year, and 3.1% for attempted suicide in life. Conclusion: the high prevalence of suicidal behavior, even with the considerable heterogeneity of the studies, raises the need to implement interventions aimed at preventing suicide and promoting mental health, especially in the academic environment.

Prevalence of Suicidal Ideation in Patients with Covid-19 in the World: Systematic Review and Meta-Analysis Protocol (Preprint)

2021 ◽  
Author(s):  
Alireza Razzaghi ◽  
Fatemeh Sadat Asgarian ◽  
Hossein Akbari
Keyword(s):  
Suicidal Ideation ◽  
Critical Appraisal ◽  
Suicide Ideation ◽  
Meta Analysis ◽  
Prevalence Data ◽  
Related Data ◽  
The World ◽  
Review Study ◽  
Meta Analyses ◽  
Analysis Protocol

BACKGROUND The pandemic of Covid-19 started in China in late 2019 and has spread rapidly around the world. Psychological problems such as suicide ideation of Covid-19 is one of the main consequences of this pandemic, which needs more attention OBJECTIVE This study aims to determine a comprehensive estimate of the prevalence of suicidal ideation in patients with Covid-19 in the world. METHODS The review study will be based on the following databases: databases of Web of Sciences, Mediline/Pubmed, Proquest, Scopus, Science Direct. This study is limited to original studies published in peer-reviewed journals in English. RESULTS The quality assessment of studies will be done using the Joanna Briggs Institute’s (JBI) critical appraisal checklist for reporting the prevalence data. The overall synthetized measurement will be presented as Prevalence with 95% confidence intervals. CONCLUSIONS This review and meta-analyses will be the first study that explores the prevalence of suicide ideation related to Covid-19. Summarizing the related data can create an image of the dimensions of the problem across the world and provide plans to prevent that.

Prevalence of suicidal ideation in pregnancy and the postpartum: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Meili Xiao ◽  
Ying Hu ◽  
Sasa Huang ◽  
Guangpeng Wang ◽  
Jinxin Zhao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Suicidal Ideation ◽  
Meta Analysis ◽  
In Pregnancy

Meta-analysis of risk factors associated with suicidal ideation after stroke:  A focus on Asian populations

2020 ◽  
Author(s):  
Shuang Mei zhang ◽  
Zhao yang Qiu ◽  
Wei feng Zhu ◽  
An rong Wang ◽  
zhaoxu zhang
Keyword(s):  
Risk Factors ◽  
Suicidal Ideation ◽  
Sleep Disorders ◽  
Household Income ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Stroke Survivors ◽  
Asian Populations ◽  
One Year ◽  
Underlying Risk

Abstract Background Over the past decade, increasing attention has been paid on post-stroke suicide (PSS), which is one of complications of stroke. The rates of stroke and suicide are relatively high, especially in Asian populations. Thus, a deeper understanding of the prevalence and epidemiological impact of suicide after stroke is urgently needed. Clinical diagnosis and prevention of PSS are at the incipient stage, but the risk factors responsible for the occurrence of PSS in different regions and stages of the disease remain largely unknown. The present meta-analysis aimed to determine the incidence of PSS at different stages and time courses, and to identify the underlying risk factors for PSS. Methods We systematically searched the Cochrane library, Embase, PubMed,CNKI and Web of Science databases from their inception until April 2019. The research articles reporting on the risk factor for PSS were screened and included in the meta-analysis. The data from the included studies were extracted according to the predefined criteria. Results A total of 12 studies (n = 2693036) were included for meta-analyses. Of these studies, 7 reported suicide prevalence were meta-analyzed. The pooled estimate of suicidal ideation rates after stroke was 12%, which could be influenced by multiple risk factors, including men, smoking, depression, sleep disorders, previous stroke and low household income. Studies conducted in Asia demonstrated higher suicide prevalence (approximately 15%) compared to other regions. Smoking, alcohol consumption, low family income, depression, heart disease and sleep disorders were the important risk factors for the pathogenesis of suicide after stroke. When compared to PSS more than one year, the incidence of suicide within one year after stroke was more likely to be statistically significant. It was found that 4 out of every 1,000 stroke survivors tended to commit suicide. The results of this meta-analysis showed that depression (OR = 2.32; p < 0.01) was significantly associated with suicidal ideation, regardless of stroke duration. Conclusion Despite some limitations, we successfully identified the prevalence of PSS in Asian populations and the underlying risk factors. Based on the results of this meta-analysis, 4 out of every 1,000 stroke survivors committed suicide and the individuals with suicidal ideation tended to suicide within one year after stroke. Notably, depression was significantly associated with suicidal ideation, regardless of stroke duration. In addition, stroke survivors with low household income had nearly double the risk of suicidal ideation, especially in Asian populations. Hence, targeting the identified risk factors may be helpful to improve stroke patient care and prevent suicidal ideation after stroke.(Registration No. CRD42019128813).

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