The relationship between mother and infant plasma trace element and heavy metal levels and the risk of neural tube defect in infants

Keban Dam Lake is the second largest dam lake in Turkey. In addition, it has the feature of being one of the most important dam lakes in our country in terms of both aquaculture potential and electricity generation. In this study, fish samples belong to Capoeta trutta caught from Örencik region of Keban Dam Lake were used. The concentrations of some heavy metals (copper, iron, zinc, chromium, nickel, cadmium, arsenic and mercury) in muscle of Capoeta trutta and the potential health risk from consumption of this fish species were examined. In addidion, the relationship between the heavy metal levels and some biological aspects of fish (weight, length and sex) were determined. As a result of the study, it was determined that the most and the least accumulated heavy metals in the muscle tissue of Capoeta trutta were zinc and cadmium respectively. The concentration of heavy metals showed differences according to weight, length and sex of fish. The results were found indicated that heavy metal levels in the muscle tissue of Capoeta trutta are below the tolerable values recommended by EPA, WHO and FAO. Therefore, there is not any risk for human consumption of this fish species.

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Evaluation of specific heavy metal levels of pregnant women complicated by neural tube defects

Annals of Medical Research ◽

10.5455/annalsmedres.2019.12.889 ◽

2020 ◽

Vol 27 (1) ◽

pp. 1

Author(s):

Talip Karaçor ◽

Pınar Kırıcı ◽

Mehmet Nacar ◽

Mehmet Bülbül ◽

Muhittin Önderci ◽

...

Keyword(s):

Heavy Metal ◽

Pregnant Women ◽

Neural Tube ◽

Neural Tube Defects ◽

Metal Levels

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An assessment of heavy metal levels in brackish water shrimps: Impact on sexes and the relationship between metal pollution index and Fulton's K condition indices

Human and Ecological Risk Assessment An International Journal ◽

10.1080/10807039.2018.1478717 ◽

2018 ◽

Vol 25 (8) ◽

pp. 1968-1979 ◽

Cited By ~ 3

Author(s):

Jalaldeen Mohamed Harris ◽

Periyathamby Vinobaba ◽

Ranil Kavindra Asela Kularatne ◽

Champika Ellawala Kankanamge

Keyword(s):

Heavy Metal ◽

Brackish Water ◽

Metal Pollution ◽

Pollution Index ◽

Metal Pollution Index ◽

Metal Levels ◽

Condition Indices ◽

The Relationship

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WHAT IS THE EFFECTS OF PARACETAMOL APPLIED AT DIFFERENT DOSES TO HEAVY METAL LEVELS IN RAT FETUS?

EurasianUnionScientists ◽

10.31618/esu.2413-9335.2020.2.78.1008 ◽

2020 ◽

Vol 2 (9(78)) ◽

pp. 9-16

Author(s):

Y. Seher Y. ◽

A. Vugar A. ◽

T. Adem T. ◽

A. Şükrü ◽

U. İlyas ◽

...

Keyword(s):

Heavy Metal ◽

Trace Element ◽

Kidney Tissue ◽

Control Group ◽

Pregnant Rats ◽

Rat Fetus ◽

Toxic Concentration ◽

Significant Difference ◽

Metal Levels ◽

Different Doses

Paracetamol is the first preferred pharmacological agent as a pain reliever and antipyretic in all periods of pregnancy. In this study, we aimed to analyze trace element and heavy metal levels in the placenta, intestinal and kidney tissues of rats in the early development period of paracetamol. Sixteen pregnant rats were randomly divided into four groups; the control group, the 50 mg/kg paracetamol group, the 250 mg/kg paracetamol group, the 500 mg/kg paracetamol group. There was a statistically significant decrease in the placental weight of the experimental groups compared to the control group. However, a statistically significant difference was found in terms of cobalt (Co) and lead (Pb) levels compared to the control group and the groups that received various doses of paracetamol. There were also statistically significant differences in intestinal chromium (Cr), selenium (Se) and cadmium (Cd) levels in the studied groups. In addition, significant differences were detected in all trace elements and heavy metal levels except Cd in the groups studied in kidney tissue (p <0.01 for all). As a result, it was determined that the use of paracetamol during pregnancy disrupted the current balance due to the increase in dose. In addition, it was observed that the weight of the placenta decreased due to the paracetamol dose, and the placenta Pb and Co levels increased. In other tissues, there was no toxic concentration at heavy metal and trace element levels, but the highest levels were determined in the control group.

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