DEFICIENCY OF THE SIXTH COMPONENT OF COMPLEMENT IN RABBITS WITH AN INHERITED COMPLEMENT DEFECT
1966 ◽
Vol 124
(4)
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pp. 773-785
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Keyword(s):
System A
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A strain of rabbits with an inherited complement deficiency was shown to lack the sixth component of the hemolytic complement system. A method was elaborated for the partial purification of this component from normal rabbit serum. Upon injection of partially purified rabbit C'6 into C'6-deficient animals, an antibody was obtained which specifically inhibited the hemolytic activity of C'6. The data suggest that C'6-deficient serum either lacks the C'6 molecule or contains it in a chemically modified and inactive form.
Keyword(s):
1980 ◽
Vol 29
(3)
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pp. 1040-1049
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Keyword(s):
1976 ◽
Vol 12
(3)
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pp. 371-374
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1943 ◽
Vol 77
(2)
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pp. 173-183
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Keyword(s):
1961 ◽
Vol 114
(6)
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pp. 875-940
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Keyword(s):
1986 ◽
Vol 250
(5)
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pp. R803-R806
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1991 ◽
Vol 260
(4)
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pp. G564-G570
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Keyword(s):