Serum and Liver Tissue Bio-Element Levels, and Antioxidant Enzyme Activities in Carbon Tetrachloride-Induced Hepatotoxicity: Protective Effects of Royal Jelly

2012 ◽  
Vol 15 (8) ◽  
pp. 747-752 ◽  
Author(s):  
Mustafa Cemek ◽  
Fatma Yılmaz ◽  
Mehmet Emin Büyükokuroğlu ◽  
Ahmet Büyükben ◽  
Fatih Aymelek ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Liver Tissue ◽  
Royal Jelly ◽  
Antioxidant Enzyme Activities ◽  
Protective Effects

Effect of diallyl disulfide on acute gastric mucosal damage induced by alcohol in rats

2014 ◽  
Vol 34 (3) ◽  
pp. 227-239 ◽  
Author(s):  
I-C Lee ◽  
H-S Baek ◽  
S-H Kim ◽  
C Moon ◽  
S-H Park ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Organosulfur Compound ◽  
Mucosal Damage ◽  
Gastric Mucosal Damage ◽  
Antioxidant Enzyme Activities ◽  
Diallyl Disulfide ◽  
Protective Effects ◽  
Tnf Α

This study investigated the gastroprotective effects of diallyl disulfide (DADS), a secondary organosulfur compound derived from garlic ( Allium sativum L.) on experimental model of ethanol (EtOH)-induced gastric ulcer in rats. The antiulcerogenic activity of DADS was evaluated by gross/histopathological inspection, pro-inflammatory cytokines, and lipid peroxidation with antioxidant enzyme activities in the stomach. DADS (100 mg/kg) was administered by oral gavage 2 h prior to EtOH treatment (5 ml/kg). The animals were killed 1 h after receiving EtOH treatment. Pretreatment with DADS attenuated EtOH-induced gastric mucosal injury, as evidenced by decreased severity of hemorrhagic lesions and gastric ulcer index upon visual inspection. DADS also prevented histopathological alterations and gastric apoptotic changes caused by EtOH. An increase in tumor necrosis factor-α (TNF-α) and inducible nitric oxide synthase was observed in the gastric tissues of EtOH-treated rats that coincided with increased serum TNF-α and interleukin 6 levels. In contrast, DADS effectively suppressed production of pro-inflammatory mediators induced by EtOH. Furthermore, DADS prevented the formation of gastric malondialdehyde and the depletion of reduced glutathione content and restored antioxidant enzyme activities, such as catalase, glutathione peroxidase, and glutathione reductase in the gastric tissues of EtOH-treated rats. These results indicate that DADS prevents gastric mucosal damage induced by acute EtOH administration in rats and that the protective effects of DADS may be due to its potent antioxidant and anti-inflammatory activities.

Protective effects of Manuka honey on LPS-treated RAW 264.7 macrophages. Part 2: Control of oxidative stress induced damage, increase of antioxidant enzyme activities and attenuation of inflammation

2018 ◽  
Vol 120 ◽  
pp. 578-587 ◽  
Author(s):  
Massimiliano Gasparrini ◽  
Sadia Afrin ◽  
Tamara Y. Forbes-Hernández ◽  
Danila Cianciosi ◽  
Patricia Reboredo-Rodriguez ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities ◽  
Raw 264.7 ◽  
Protective Effects ◽  
Manuka Honey ◽  
Raw 264.7 Macrophages

scholarly journals Organik ve İnorganik Selenyum Katkılı Yemlerle Beslenen Oreochromis niloticus ’da Antioksidan ve İmmün Sistem Parametrelerinin Araştırılması

2017 ◽  
Vol 5 (12) ◽  
pp. 1454
Author(s):  
Arzu Özlüer Hunt ◽  
Ferbal Özkan-Yılmaz ◽  
Şanser Delioğlan ◽  
Mehmet Berkoz
Keyword(s):  
Antioxidant Enzyme ◽  
Oreochromis Niloticus ◽  
Enzyme Activities ◽  
Liver Tissue ◽  
Antioxidant Enzyme Activities ◽  
System Parameters ◽  
Organic Selenium ◽  
Selenium Accumulation ◽  
Muscle Tissues ◽  
Inorganic Selenium

In this study, antioxidant enzyme activities and immun system parameters of liver tissue of Oreochromis niloticus fed with organic (Sel-Plex®-2000, Alltech, USA) and inorganic selenium (Na2SeO3.5H2O - Sodium selenite pentahydrate-FLUCA) supplemented feed were investigated. The fish with average weights of 12.62 ± 0.11 g were placed in aquariums and fed for 75 days in 5 different application groups (Control; Org1.5; Org3.0; Inorg1.5; Inorg3.0). At the end of the trial period, catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), lysozyme (LYZ) and myeloperoxidase (MPO) activities and MDA level in the liver tissue and selenium accumulation in the muscle was determined. The antioxidant enzyme activities and immune system parameters in liver were increased in all Se groups compared to control. Se levels in muscle tissues significantly increased in all tested selenium groups when compared to control. In fish fed with 3mg/kg of organic selenium, muscle selenium levels were found to be higher than other groups.

Protective effects of unsaponifiable matter from rice bran on oxidative damage by modulating antioxidant enzyme activities in HepG2 cells

LWT ◽  
2015 ◽  
Vol 61 (2) ◽  
pp. 602-608 ◽  
Author(s):  
Hyeonmi Ham ◽  
Sung Won Yoon ◽  
In-Hwan Kim ◽  
Jieun Kwak ◽  
Jeom-Sig Lee ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Antioxidant Enzyme ◽  
Unsaponifiable Matter ◽  
Rice Bran ◽  
Enzyme Activities ◽  
Hepg2 Cells ◽  
Antioxidant Enzyme Activities ◽  
Protective Effects

scholarly journals Antioxidant enzyme activities in liver tissue of chickens fed diets supplemented with various forms and amounts of selenium

2003 ◽  
Vol 12 (1) ◽  
pp. 143-152 ◽  
Author(s):  
K. Holovská Jr. ◽  
K. Holovská ◽  
K. Boldižárová ◽  
S. Čekonová ◽  
V. Lenártová ◽  
...  
Keyword(s):  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Liver Tissue ◽  
Antioxidant Enzyme Activities

Effects of copper oxide nanoparticles on antioxidant enzyme activities in liver tissue of Clarias gariepinus

2017 ◽  
Vol 280 ◽  
pp. S186
Author(s):  
Mustafa Tuncsoy ◽  
Servet Duran ◽  
Ozcan Ay ◽  
Bedii Cicik ◽  
Cahit Erdem
Keyword(s):  
Copper Oxide ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Liver Tissue ◽  
Clarias Gariepinus ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Antioxidant Enzyme Activities
Sign in / Sign up

Export Citation Format

Share Document