Mathematical applications associated with the deliberate release of infectious agents

Author(s):  
Gerardo Chowell ◽  
Ariel Cintrón-Arias ◽  
Sara Del Valle ◽  
Fabio Sánchez ◽  
Baojun Song ◽  
...  
Author(s):  
Stephen Palmer

Since 9/11 2001, international attention has once again focused on the risks to human and animal health from the deliberate release of infectious or toxic chemical agents. In theory any agent could be used by terrorists and disaffected people, but the most serious risk for infectious agents are mainly zoonotic (Franz et al. 1997). Three modes of exposure may be anticipated, inhalation of powder or spray or dust from explosives, direct contact or inoculation from an explosion, and ingestion. Centers for Disease Control (CDC) list 19 bioterrorism agents or groups of agents of which 14 are zoonotic. In Category A are 6 agents which can be easily disseminated or transmitted from person to person, that result in high mortality rates and have the potential for major public health impact, which might cause public panic and social disruption and which require special action from public health preparedness. Of these 6, four are zoonoses — Anthrax, Plague, Tularaemia and Viral Haemorrhagic Fevers. In Category B, are 12 groups of agents, which are moderately easy to disseminate and cause moderate morbidity. Of these 12 groups, 8 contain zoonoses: Brucellosis, Food Safety threats (e.g. Salmonella, E.coli 0157, Campylobacter), Meliodiosis, Psittacoccosis, Q Fever, Typhus, Viral encephalitis, Water safety threats (e.g. Cryptosporidium).


Author(s):  
A. W. Fetter ◽  
C. C. Capen

Atrophic rhinitis in swine is a disease of uncertain etiology in which infectious agents, hereditary predisposition, and metabolic disturbances have been reported to be of primary etiologic importance. It shares many similarities, both clinically and pathologically, with ozena in man. The disease is characterized by deformity and reduction in volume of the nasal turbinates. The fundamental cause for the localized lesion of bone in the nasal turbinates has not been established. Reduced osteogenesis, increased resorption related to inflammation of the nasal mucous membrane, and excessive resorption due to osteocytic osteolysis stimulated by hyperparathyroidism have been suggested as possible pathogenetic mechanisms.The objectives of this investigation were to evaluate ultrastructurally bone cells in the nasal turbinates of pigs with experimentally induced atrophic rhinitis, and to compare these findings to those in control pigs of the same age and pigs with the naturally occurring disease, in order to define the fundamental lesion responsible for the progressive reduction in volume of the osseous core.


2020 ◽  
Vol 142 ◽  
pp. 105-118
Author(s):  
CC Sauvé ◽  
A Hernández-Ortiz ◽  
E Jenkins ◽  
F Mavrot ◽  
A Schneider ◽  
...  

The population of grey seals Halichoerus grypus in Canadian waters is currently used as a commercial source of meat for human consumption. As with domestic livestock, it is important to understand the occurrence in these seals of infectious agents that may be of public health significance and thus ensure appropriate measures are in place to avoid zoonotic transmission. This study examined the prevalence of antibodies against Brucella spp., Erysipelothrix rhusiopathiae, 6 serovars of Leptospira interrogans, and Toxoplasma gondii in 59 grey seals and determined by polymerase chain reaction (PCR) the presence of these potentially zoonotic agents in specific organs and tissues of seropositive animals. The presence of encysted Trichinella spp. larvae was also investigated by digestion of tongue, diaphragm and other muscle samples, but none were detected. Seroprevalence against Brucella spp. and E. rhusiopathiae was low (5 and 3%, respectively). All 59 seals tested had antibodies against L. interrogans, but no carrier of this bacterium was detected by PCR. Seroprevalence against T. gondii was 53%, and DNA of this protozoan was detected by PCR in 11/30 (37%) seropositive animals. Standard sanitary measures mandatory for commercialization of meat products for human consumption should greatly reduce the potential for exposure to these infectious agents. However, special consideration should be given to freezing seal meat for at least 3 d to ensure destruction of tissue cysts of T. gondii.


2019 ◽  
Vol 81 (6) ◽  
pp. 45-57
Author(s):  
L.A. Dankevych ◽  
◽  
F.V. Muchnyk ◽  
V.P. Patyka ◽  
◽  
...  

2011 ◽  
Vol 6 (4) ◽  
pp. 1-6
Author(s):  
Cheryl Seals ◽  
◽  
Cheryl Swanier ◽  
Justus N. Nyagwencha ◽  
Ashley L. Cagle ◽  
...  

2019 ◽  
Vol 1 (4) ◽  
pp. 1-10 ◽  
Author(s):  
Shafiu Ibrahim Abdullahi

The significance of the Zakah institution to any Islamic economy, it links to financial viability and economic progress has made it a must to modernize the sector to go in line with modern realities. Poor management of Zakah institutions has been described as detrimental to the efforts of these institutions to collect and disburse Zakah effectively. This paper looks at applications of mathematical and quantitative techniques with the view to achieving optimality and efficiency in business of collection and disbursement of Zakah. The mathematical applications tested are the techniques of contribution maximization, programming, and game theory. The potential applications of this field of mathematics to Zakah operations are vast. It calls for concerted efforts and focuses by researchers, policymakers and Islamic scholars on finding the most efficient way of deploying operation research techniques in the management of Zakah institutions.  


2018 ◽  
Vol 1 (2) ◽  
pp. 166
Author(s):  
Sutriswanto Sutriswanto ◽  
Sugito Sugito

Abstract: Staphylococcus is a cause of infection. Infection can be transmitted from a source by an indirect through fomite. Paper money can act as transmission of infectious agents, money acts as a fomite. Smaller denominations of value have higher contamination. This study aims to analyze differences in contamination bacterial Staphylococcus sp on denomination of paper money Rp.2.000, 5.000, Rp.10,000 and Rp.20.000 that currently shop on Adi Sucipto street town Pontianak. The research method used in this research is in the form of difference and the sample in this research is denomination of paper money curently with sampling technique using cluster sampling. Checkup of Staphylococcus spon denomination of paper money using rinse method. On these result of study, denomination of paper money Rp.2.000 that is contaminated staphylococcus sp is 80%, denomination of paper money Rp.5.000 that is contaminated staphylococcus sp is 70%, denomination of paper money Rp.10.000 and Rp.20.000 that is contaminated staphylococcus sp is 80%. The data from result of study has been obtained were analyzed statistically by using fisher exact test, the result of p (0,477) >α (0,05) which mean as H1 is rejected. So it can be concluded there is no difference of contamination bacteria staphylococcus sp on denominations of paper money rupiah.Abstrak: Staphylococcus merupakan penyebab terjadinya infeksi. Infeksi dapat ditularkan dari suatu sumber dengan mekanisme tidak langsung melalui fomite. Uang kertas dapat bertindak sebagai transmisi agens infeksius ,uang berperan sebagai fomite. Pecahan uang yang lebih kecil nilainya memiliki kontaminasi yang lebih tinggi. Penelitian ini bertujuan untuk menganalisis perbedaan cemaran bakteri Staphylococcus sp pada pecahan uang kertas Rp.2.000, 5.000, Rp.10.000 dan Rp.20.000 yang beredar di warung jalan Adi Sucipto kota Pontianak. Metode penelitian yang digunakan dalam penelitian berbentuk komperatif dan sampel pada penelitian ini adalah pecahan uang kertas rupiah dengan.teknik pengambilan sampel menggunakan purposive sampling. Pemeriksaan Staphylococcus sp pada pecahan uang kertas rupiah menggunakan metode rinse. Pada hasil penelitian pecahan uang kertas Rp.2.000 yang tercemar staphylococcus sp adalah 80%, pecahan uang kertas Rp.5.000 yang tercemar staphylococcus spadalah 70%, pecahan uang kertas Rp.10.000 dan Rp.20.000 yang tercemar staphylococcus spadalah 50%. Berdasarkan data dari hasil penelitian yang telah didapat dianalisis menggunakan uji statistik fisher exact, didapatkan hasil p (0,477) >α (0,05) yang diartikan sebagai H1 ditolak. Sehingga dapat disimpulkan tidak ada perbedaan cemaran bakteri staphylococcus sp pada pecahan uang kertas rupiah.


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