scholarly journals The need to connect: on the cell biology of synapses, behaviors, and networks in science

2016 ◽  
Vol 27 (21) ◽  
pp. 3203-3207
Author(s):  
Daniel A. Colón-Ramos

My laboratory is interested in the cell biology of the synapse. Synapses, which are points of cellular communication between neurons, were first described by Santiago Ramón y Cajal as “protoplasmic kisses that appear to constitute the final ecstasy of an epic love story.” Who would not want to work on that?! My lab examines the biological mechanisms neurons use to find and connect to each other. How are synapses formed during development, maintained during growth, and modified during learning? In this essay, I reflect about my scientific journey to the synapse, the cell biological one, but also a metaphorical synapse—my role as a point of contact between the production of knowledge and its dissemination. In particular, I discuss how the architecture of scientific networks propels knowledge production but can also exclude certain groups in science.

2002 ◽  
Vol 19 (4) ◽  
pp. 1-22 ◽  
Author(s):  
Jasmin Zine

This paper examines the politics of knowledge production as it relates to Muslim women in western literary traditions and con­temporary feminist writing, with a view to understanding the political, ideological, and economic mediations that have histor­ically framed these representations. The meta-narrative of the Muslim woman has shifted from the bold queens of medieval lit­erature to colonial images of the seraglio's veiled, secluded, and oppressed women. Contemporary feminist writing and popular culture have reproduced the colonial motifs of Muslim women, and these have regained currency in the aftermath of9/1 l. Drawing upon the work of Mohja Kahf, this paper begins by mapping the evolution of the Muslim woman archetype in western literary traditions. The paper then examines how some contemporary feminist literature has reproduced in new ways the discursive tropes that have had historical currency in Muslim women's textual representation. The analysis is atten­tive to the ways in which the cultural production of knowledge about Muslim women has been implicated historically by the relations of power between the Muslim world and the West ...


2021 ◽  
pp. 1-45
Author(s):  
Susan Elizabeth Gagliardi ◽  
Constantine Petridis

Abstract Mapping Senufo: Art, Evidence, and the Production of Knowledge – an in-progress, collaborative, born-digital publication – will offer a model for joining theories about the construction of identities and the politics of knowledge production with research and publication practice. In this article, we examine how computational methods have led us to reframe research questions, reevaluate sources, and reimagine the form of a digital monograph. We also demonstrate how our use of digital technologies, attention to iteration, and collaborative mode of working have generated fresh insights into a corpus of arts identified as Senufo, the nature of evidence for art-historical research, and digital publication. We posit that the form of a digital publication itself can bring processes of knowledge construction to the fore and unsettle expectations of a tidy, authoritative narrative.


Minerva ◽  
2022 ◽  
Author(s):  
Aitor Anduaga

AbstractThe why and the how of knowledge production are examined in the case of the transnational cooperation between the directors of observatories in the Far East who drew up unified typhoon-warning codes in the period 1900–1939. The why is prompted by the socioeconomic interests of the local chambers of commerce and international telegraphic companies, although this urge has the favourable wind of Far Eastern meteorologists’ ideology of voluntarist internationalism. The how entails the persistent pursuit of consensus (on ends rather than means) in international meetings where non-binding resolutions on codes and procedures are adopted. The outcome is the co-production of standardised knowledge, that is, the development of a series of processes and practices that co-produce both knowledge and ideas about the social order in a force field characterised by negotiations and power struggles.


Roteiro ◽  
2016 ◽  
Vol 41 (3) ◽  
pp. 649
Author(s):  
Alexandre Vanzuita ◽  
Tânia Regina Raitz

<p><strong>Resumo</strong>:<strong> </strong>Neste estudo analisamos como as experiências no contexto de formação e inserção profissional em Educação Física constroem identidade(s) profissional(is). Trata-se de um ensaio teórico-reflexivo por meio da produção do conhecimento (2009 a 2015) das variáveis relacionadas à identidade e inserção profissional em Educação Física. Identificamos na literatura cinzenta problemática reduzida, portanto, há necessidade de intensificar os estudos em razão das transformações no mundo do trabalho e das dificuldades de inserção desses profissionais. Concluímos que as experiências no contexto da formação e inserção profissional não estão articuladas integralmente aos processos de pesquisa e construção de métodos e metodologias.<strong></strong></p><p><strong>Palavras-chave</strong>: Produção de conhecimento. Identidade profissional. Inserção profissional.</p><p align="center">CONSTRUCTION OF PROFESSIONAL IDENTITY IN PHYSICAL EDUCATION: A LITERATURE REVIEW </p><p><strong>Abstract</strong>:<strong> </strong>In this study we examines how experiences in the context of training and employability in Physical Education build professional(ies) identity(ies). It is a reflective theoretical essay through the production of knowledge (2009-2015) related to identity and employability in Physical Education. We identified in reduced problematic gray literature, therefore, there is need to intensify their studies due to changes in the workplace and integration difficulties of these professionals. We concluded that the experiences in the training and professional integration are not fully articulated to the research processes and construction methods and methodologies.</p><p><strong>Keywords</strong>: Knowledge production. Professional identity. Employability.</p><p align="center"><strong><br /></strong></p><p align="center">CONSTRUCCIÓN DE LA IDENTIDAD PROFESIONAL EN LA EDUCACIÓN FÍSICA: UNA REVISIÓN DE LA LITERATURA</p><p align="center"><strong> </strong></p><p><strong>Resumen: </strong>Este estudio examina cómo las experiencias en el contexto de la formación y la empleabilidad en Educación Física construyen la identidad(s) profesional(s). Se trata de un ensayo teórico reflexivo de la producción de conocimiento (2009 a 2015) relacionadas con la identidad y la empleabilidad en Educación Física. Fue identificado reducida literatura, por lo que existe la necesidad de intensificar sus estudios debido a cambios en mundo del trabajo e dificultades de integración de estos profesionales. Se concluye que las experiencias en la formación e inserción profesional no se articulan totalmente los procesos de investigación y construcción de métodos y metodologías.</p><p><strong>Palabras-clave</strong>: Producción de conocimiento. Identidad profesional. Empleabilidad.</p>


2008 ◽  
Vol 30 (4) ◽  
pp. 26-32 ◽  
Author(s):  
Gideon J. Davies ◽  
Michael L. Sinnott

Carbohydrates offer a structural and chemical diversity unrivalled in Nature: two glucose residues can be joined together in 30 different ways, and, with six different sugars, the number of possible isomers exceeds 1012 [1]. This huge diversity is reflected in the diverse roles for carbohydrates in Nature. Mono, di, oligo and polysaccharides and glycoconjugates play myriad roles in biology, in addition to wellknown ones such as energy storage (starch, glycogen) and maintenance of structure (cellulose, chitin, alginate). The diversity of what is sometimes called the ‘glycome’ also provides for a subtle means of cellular communication in higher organisms: carbohydrates are the language of the cell. Sugarmediated interactions not only are important for the communication of healthy cells, but also play crucial roles in disease, viral invasion and bacterial attack and malignancy. Sharon [2] has termed the challenge of carbohydrates as “the last frontier of molecular and cell biology”. There is thus considerable interest in the enzymes whose job it is to modify and cleave carbohydrates [GHs (glycoside hydrolases) and lyases] and those involved in their biosynthesis, GTs (glycosyltransferases). Typically, these enzymes make up approx. 1–2% of the genome of any organism [3]. Thus, at the time of writing, there are around 70000 ORFs (open reading frames) known which potentially encode GHs or GTs. A major goal for the scientific community is to extract useful informa tion on the enzymes encoded by these ORFs from sequence alone. This is an enormous challenge, one complicated by the modular nature of the enzymes themselves [4].


2021 ◽  
pp. 155-179
Author(s):  
Andrea Bianchi

How knowledge of international law is produced, by what forces and processes it is shaped, how one can determine what issues are deemed relevant to the field, what questions can be competently raised by the members of the profession and the discipline, and who has the authority to provide them with an answer, are all issues that lie at the heart of this chapter. Particular attention will be paid to the concepts of both epistemic communities and discursive policies. In light of the interaction of the different forces and actors at play in the production of knowledge, an attempt will be made to sketch out the main trends of the contemporary episteme of international law. The final part of the chapter tackles the issue of how to bring to light and make visible the invisible frames of knowledge production in international law, by using critical theory and the power of legal imagination.


2018 ◽  
Vol 25 (1) ◽  
pp. 508 ◽  
Author(s):  
Elizabeth Reddy

AbstractA single technoscientific knowledge project can entail many different kinds of knowledge production. Here, I show how a Mexican technoscientific knowledge project about seismicity requires diverse sensory practices and the production of knowledge about many kinds of environmental and social conditions. I argue that Mexican territorial politics frame this knowledge. Further, I demonstrate that these politics become evident in the very ways that knowledge about Mexico is configured spatially, that is, in topological and topographic ways that technicians and engineers come to understand and relate to Mexican territory. After situating this argument within contemporary critical attention to the production of geographic knowledge, I address it ethnographically. First, I describe how Mexican seismic monitoring is undertaken from the headquarters of the Centro de Instrumentación y Registro Sísmico (CIRES). Then, I deal with the arrangements of power that structure seismic monitoring and social conditions in what CIRES engineers and technicians call "the field." As I relate the sensory work and knowledge production that field teams do when they leave CIRES headquarters, I show how the things that field teams can know are shaped by territorial politics, and consequently reflect them.Key Words: Mexico, environmental monitoring, sense, knowledge, earthquakes


2012 ◽  
Vol 55 (2-3) ◽  
pp. 603-636 ◽  
Author(s):  
Filipa Lowndes Vicente

Abstract By analyzing the history of a photograph taken in a Bombay photo studio in 1885, this article explores notions of the production of knowledge on India and cultural dialogues, encounters, appropriations, and conflicts in colonial British India in the late nineteenth century. The photograph was taken after a Hindu religious ceremony in honour of the Italian Sanskritist Angelo de Gubernatis. Dressed as a Hindu Brahman, he is the only European photographed next to three Indian scholars, but what the image suggests of encounter and hybridity was challenged by the many written texts that reveal the conflicting dialogues that took place before and after the portrait was taken. Several factors were examined in order to decide who should and who should not be in the photograph: religion, cast, and even gender were successively discussed, before the category of “knowledge” became the bond that unified the four men who studied, taught, and wrote on India.


2017 ◽  
Vol 18 (1) ◽  
pp. 106-128 ◽  
Author(s):  
Čarna Brković

This article's concern is epistemological in that it seeks understanding of the nature of ethnographic knowledge production. Its background assumption is that decolonization of anthropology requires decolonization of anthropological epistemology. The article argues that anthropology is not so much a study of the ‘Other’, but an effort to acquire knowledge by translating across some sort of socio-historically established difference. Anthropologists do not acquire knowledge necessarily by translating between modern, Western European, and non-modern, ‘Other’ conceptual arrangements. Instead, the anthropological production of knowledge requires an effort to figure out the relevant differences and similarities between an anthropologist, their interlocutors, and their audiences, as well as a translation across these differences and similarities. In order to demonstrate this point, the article focuses on 19th- and 20th-century ethnographic discussions of rural joint families called zadruga in the Balkans. Through a critical reading of two works on zadruga, it demonstrates that anthropologists in the Balkans were epistemologically eclectic, in that they could make use of strategies of both ‘anthropology abroad’ and ‘auto-anthropology’, or combine and reverse them. While this instance of epistemological eclecticism is the result of widespread uncertainties concerning the status of the ‘modern’ and the ‘non-modern’ as organizational categories in the Balkans, it has direct implications for the production of anthropological knowledge generally.


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