scholarly journals Diet Quality Indices and Risk of Type 2 Diabetes Mellitus

2018 ◽  
Vol 187 (12) ◽  
pp. 2651-2661 ◽  
Author(s):  
Guo-Chong Chen ◽  
Woon-Puay Koh ◽  
Nithya Neelakantan ◽  
Jian-Min Yuan ◽  
Li-Qiang Qin ◽  
...  

Abstract We aimed to test whether predefined dietary patterns that are inversely related to risk of type 2 diabetes (T2D) in Western populations were similarly associated with lower T2D risk in an Asian population. We included 45,411 middle-aged and older participants (ages 45–74 years) in the Singapore Chinese Health Study who were free of diabetes, cancer, and cardiovascular disease at baseline (1993–1998). Participants were followed up for T2D diagnosis through 2010. Dietary information was collected using a validated food frequency questionnaire. Dietary pattern scores were calculated for the alternate Mediterranean diet (aMED), Alternate Healthy Eating Index 2010 (AHEI-2010), the Dietary Approaches to Stop Hypertension (DASH) diet, an overall plant-based diet index, and a healthful plant-based diet index. During a median of 11.1 years of follow-up, 5,207 incident cases of T2D occurred. After adjustment for multiple potential confounders, the 5 dietary pattern scores were significantly associated with 16% (for aMED) to 29% (for DASH) lower risks of T2D when comparing the highest score quintiles with the lowest (all P-for-trend values < 0.001). These associations did not vary substantially by baseline age, sex, body mass index, or hypertension status but were limited to nonsmokers (aMED: P for interaction < 0.001; AHEI-2010: P for interaction = 0.03). Adherence to a high-quality diet, as reflected by several predefined diet quality indices derived in Western populations, was significantly associated with lower T2D risk in an Asian population.

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Roxaneh Sadat Ziaee ◽  
Parisa Keshani ◽  
Moosa Salehi ◽  
Haleh Ghaem

Background. The study aimed to determine the correlation between different diet quality indices and glycemic status and lipid profile in patients with diabetes. Methods. This study was carried out on 235 patients with type 2 diabetes referred to Martyr Motahari Diabetes Clinic of Shiraz city so as to investigate the relationship between glycemic status and lipid profile and the diet quality using Healthy Eating Index (HEI-2010), phytochemical index (PI), and Diet Quality Index-International (DQI_I). Results. A positive correlation was indicated between the serum levels of LDL-C and HEI-2010 scores p = 0.026 . Furthermore, there was a positive correlation between the patients’ age and scores of PI p = 0.006 and between PI and DQI_I p < 0.001 . There was no significant relationship between the scores for all three indicators and biochemical parameters. Conclusion. The results of this study indicated that there was a significant correlation between the serum LDL-C levels and the HEI-2010 scores. Moreover, the age of the patients had a direct correlation with the PI scores.


2017 ◽  
Vol 118 (4) ◽  
pp. 312-320 ◽  
Author(s):  
Simone Jacobs ◽  
Carol J. Boushey ◽  
Adrian A. Franke ◽  
Yurii B. Shvetsov ◽  
Kristine R. Monroe ◽  
...  

AbstractDietary indices have been related to risk for type 2 diabetes (T2D) predominantly in white populations. The present study evaluated this association in the ethnically diverse Multiethnic Cohort and examined four diet quality indices in relation to T2D risk, homoeostatic model assessment-estimated insulin resistance (HOMA-IR) and biomarkers of dyslipidaemia, inflammation and adipokines. The T2D analysis included 166 550 white, African American, Native Hawaiian, Japanese American and Latino participants (9200 incident T2D cases). Dietary intake was assessed at baseline using a quantitative FFQ and T2D status was based on three self-reports and confirmed by administrative data. Biomarkers were assessed about 10 years later in a biomarker subcohort (n 10 060). Sex- and ethnicity-specific hazard ratios were calculated for the Healthy Eating Index-2010 (HEI-2010), the alternative HEI-2010 (AHEI-2010), the alternate Mediterranean diet score (aMED) and the Dietary Approaches to Stop Hypertension (DASH). Multivariable-adjusted means of biomarkers were compared across dietary index tertiles in the biomarker subcohort. The AHEI-2010, aMED (in men only) and DASH scores were related to a 10–20 % lower T2D risk, with the strongest associations in whites and the direction of the relationships mostly consistent across ethnic groups. Higher scores on the four indices were related to lower HOMA-IR, TAG and C-reactive protein concentrations, not related to leptin, and the DASH score was directly associated with adiponectin. The AHEI-2010 and DASH were directly related to HDL-cholesterol in women. Potential underlying biological mechanisms linking diet quality and T2D risk are an improved lipid profile and reduced systemic inflammation and, with regards to DASH alone, an improved adiponectin profile.


2017 ◽  
Vol 20 (16) ◽  
pp. 2909-2919 ◽  
Author(s):  
Grace Kollannoor-Samuel ◽  
Sofia Segura-Pérez ◽  
Fatma M Shebl ◽  
Nicola L Hawley ◽  
Grace Damio ◽  
...  

AbstractObjectiveThe study aims were to (i) identify determinants of Nutrition Facts Panel (NFP) use and (ii) describe the association between NFP use and dietary intake among Latinos with type 2 diabetes.DesignBaseline cross-sectional data from a clinical trial were used to assess the association between NFP use and dietary intake. Diet was measured using two methods: (i) a diet quality score (the Healthy Eating Index-2010) derived from a single 24 h recall and (ii) dietary pattern (exploratory factor analyses) from an FFQ. Multivariable logistic and non-parametric quantile regressions were conducted, as appropriate.SettingsHartford County, Connecticut, USA.SubjectsLatino adults (n 203), ≥21 years of age, with diagnosed type 2 diabetes, glycosylated Hb≥7 %, and without medical conditions limiting physical activity.ResultsParticipants’ education level, diabetes-related knowledge and English speaking were positively associated with NFP use. At the higher percentiles of diet quality score, NFP use was significantly associated with higher diet quality. Similarly, NFP users were more likely to consume a ‘healthy’ dietary pattern (P=0·003) and less likely to consume a ‘fried snack’ pattern (P=0·048) compared with NFP non-users.ConclusionsThe association between reported NFP use and diet quality was positive and significantly stronger among participants who reported consuming a healthier diet. While NFP use was associated with a healthier dietary pattern, not using NFP was associated with a less-healthy, fried snack pattern. Longitudinal studies are needed to understand whether improving NFP use could be an effective intervention to improve diet quality among Latinos with type 2 diabetes.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1401-1401 ◽  
Author(s):  
Teresa Fung ◽  
Sabri Bromage ◽  
Yanping Li ◽  
Shilpa Bhupathiraju ◽  
Carolina Batis ◽  
...  

Abstract Objectives No tool to measure diet quality on the global scale currently exist. At the same time, type 2 diabetes is a global issue for women, including those under age 50. As part of an effort to develop an instrument to assess diet quality, this analysis the ability of a global diet quality score to predict type 2 diabetes in women in a high-income country. Therefore, the objective of this analysis is to examine prospectively the association between the Global Diet Quality Score (GDQS) and risk of type 2 diabetes, and potential differences in association by age, among U.S. women. Methods Health, lifestyle, and diet information was collected from women (n = 88,520) in the Nurses’ Health Study II through repeated questionnaires between 1991 and 2017. The GDQS consisted of 25 food groups and points were awarded for higher intake of healthy groups and lower intake of unhealthy groups (maximum of 49 points). Multivariable hazard ratios (HR) were computed for confirmed type 2 diabetes using Cox proportional hazards models. Results We ascertained 6319 incident type 2 diabetes during follow-up. The multivariable HR comparing top to bottom quintile of GDQS was 0.83 (95% CI = 0.76–0.91, p trend &lt; 0.001). The association for women under age 50 was 0.77 (0.68–0.88, p trend &lt; 0.001) and for age 50+ was 0.69 (0.52–0.93, p trend &lt; 0.001) with no significant interaction. Analysis of the healthy and unhealthy subscores of the GDQS showed an inverse association with lower intake of unhealthy components (HR comparing top to bottom quintile of the unhealthy subscore = 0.69, 95% CI = 0.62–0.77, p trend &lt; 0.001) but not higher intake of healthy components. The inverse association for each 1-SD increase in the GDQS (HR = 0.93, CI = 0.91–0.96) was stronger (P &lt; 0.001) than the Minimum Diet Diversity score for Women (MDDW) (HR = 1.00, CI = 0.94–1.04) but slightly weaker (P = 0.03) than the Alternate Healthy Eating Index-2010 (AHEI-2010) (HR = 0.91, CI = 0.88–0.94). Conclusions A higher GDQS was inversely associated with type 2 diabetes risk in U.S. women, mainly due to lower intake of unhealthy foods. The association did not appear to differ by age. The GDQS performed nearly as well as the AHEI-2010. Funding Sources Funding for this work was provided by Intake - Center for Dietary Assessment at FHI Solutions.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Danielle E Haslam ◽  
Dong Wang ◽  
Liming Liang ◽  
Rachel S Kelly ◽  
Clemens Wittenbecher ◽  
...  

Introduction: Puerto Rican (PR) adults living on the US mainland are at high risk for developing type 2 diabetes (T2D), and dietary factors may contribute to this increased risk. Network analysis is a data-reduction tool that can identify correlated clusters of co-regulated metabolites that reflect mechanisms underlying diet-T2D associations. Hypothesis: Diet quality will associate with T2D-associated metabolite clusters among PR adults. Methods: We used LC/MS to measure fasting plasma metabolites (>700) among Boston PR Health Study participants, aged 45-75 years, with (n=258) and without (n=421) T2D. We applied an unsupervised correlation network-based method to identify metabolite clusters within a global metabolite network and calculated a score for each cluster using a weighted sum of metabolite concentrations. To estimate diet quality, we calculated a modified version of a previously validated American Heart Association diet score (AHA-DS). Logistic regression was used to assess cross-sectional associations between metabolite clusters and prevalent T2D, and linear regression was used to assess associations between the continuous AHA-DS and T2D-associated metabolite clusters among controls, adjusting for potential confounders and correcting for multiple testing. Results: We identified 7 metabolite clusters that were associated with prevalent T2D ( p <0.05). For every 1-standard deviation (SD) increase in cluster score, the odds ratios for prevalent T2D and 95% confidence intervals were as the follows: acylcholines [0.40 (0.31, 0.50)], aromatic hydrocarbon derivatives [0.33 (0.22, 0.47)], sphingolipids [0.46 (0.33, 0.64)], tricarboxylic acid (TCA) cycle amino acids/peptides [0.39 (0.25, 0.62)], branched-chain amino acid metabolites [4.1 (2.9, 6.0)], acylcarnitines [1.8 (1.3, 2.5)], and TCA cycle/energy metabolites [2.0 (1.4, 3.0)]. The AHA-DS was only significantly associated with the acylcholine metabolites cluster [β (standard error) = 0.01 (0.004) SD increase in cluster score, p=0.02]. Conclusions: In individuals of PR descent, we identified a cluster of acylcholine metabolites where concentrations are higher among those with better diet quality and lower among those with prevalent T2D.


2013 ◽  
Vol 28 (2) ◽  
pp. 145-153 ◽  
Author(s):  
Anne E. Coltman ◽  
Kathryn S. Keim ◽  
Karen M. Chapman-Novakofski ◽  
Christopher A. Taylor

2015 ◽  
Vol 114 (10) ◽  
pp. 1694-1701 ◽  
Author(s):  
Ming Ding ◽  
Adrian A. Franke ◽  
Bernard A. Rosner ◽  
Edward Giovannucci ◽  
Rob M. van Dam ◽  
...  

AbstractTo examine the association between urinary excretion of isoflavonoids and risk of type 2 diabetes (T2D), we conducted a nested case–control study among 1111 T2D pairs identified during 1995–2008 in the Nurses’ Health Study (NHS) and NHSII, who were free of diabetes, CVD and cancer at urine sample collection. Urinary excretion of daidzein and genistein, as well as their metabolites O-desmethylangolensin (O-DMA), dihydrogenistein (DHGE) and dihydrodaidzein (DHDE) was assayed using liquid chromatography MS. Self-reported T2D incident cases were confirmed using a validated questionnaire. Higher urinary excretion of daidzein and genistein was associated with a lower risk of T2D in the combined cohorts. Comparing extreme tertiles of the urinary markers, the OR of T2D were 0·71 (95 % CI 0·55, 0·93) for daidzein and 0·74 (95 % CI 0·56, 0·97) for genistein, although the test for linear trend was not significant for genistein (Ptrend=0·03 and 0·15, respectively). DMA, DHDE and DHGE were non-significantly associated with a lower T2D risk. The inverse association of daidzein with T2D risk was stronger among post-menopausal women who did not use hormone replacement therapy (Pinteraction=0·001): the OR was 0·58 (95 % CI 0·34, 0·97) comparing extreme tertiles among these women. In conclusion, urinary excretion of isoflavones was associated with a lower T2D risk in US women, especially among post-menopausal women who did not use hormone. Further research is warranted to replicate these observations among western populations with similarly low overall isoflavone intake.


Gut ◽  
2020 ◽  
pp. gutjnl-2020-322557 ◽  
Author(s):  
Jinqiu Yuan ◽  
Qiangsheng He ◽  
Long H Nguyen ◽  
Martin C S Wong ◽  
Junjie Huang ◽  
...  

ObjectiveThe association between the regular use of proton pump inhibitors (PPIs) and the risk of type 2 diabetes remains unclear, although a recent randomised controlled trial showed a trend towards increased risk. This study was undertaken to evaluate the regular use of PPIs and risk of type 2 diabetes.MethodThis is a prospective analysis of 204 689 participants free of diabetes in the Nurses' Health Study (NHS), NHS II and Health Professionals Follow-up Study (HPFS). Type 2 diabetes was confirmed using American Diabetes Association (ADA) diagnostic criteria. We evaluated hazard ratios (HRs) adjusting for demographic factors, lifestyle habits, the presence of comorbidities, use of other medications and clinical indications.ResultsWe documented 10 105 incident cases of diabetes over 2 127 471 person-years of follow-up. Regular PPI users had a 24% higher risk of diabetes than non-users (HR 1.24, 95% CI 1.17 to 1.31). The risk of diabetes increased with duration of PPI use. Fully adjusted HRs were 1.05 (95% CI 0.93 to 1.19) for participants who used PPIs for >0–2 years and 1.26 (95% CI 1.18 to 1.35) for participants who used PPIs for >2 years compared with non-users.ConclusionsRegular use of PPIs was associated with a higher risk of type 2 diabetes and the risk increased with longer duration of use. Physicians should therefore exercise caution when prescribing PPIs, particularly for long-term use.


Nutrients ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 8 ◽  
Author(s):  
Sihan Song ◽  
Jung Lee

We aimed to examine whether dietary patterns that explain the variation of triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) ratio were associated with the incidence of type 2 diabetes in Korean adults. We included a total of 5097 adults without diabetes at baseline with a mean follow-up of 11.54 years. Usual diet was assessed by a validated food frequency questionnaire, and serum levels of TG and HDL-C were measured at baseline. We derived dietary pattern scores using 41 food groups as predictors and the TG/HDL-C ratio as a response variable in a stepwise linear regression. We calculated the odds ratio (OR) with the 95% confidence interval (CI) of type 2 diabetes according to pattern scores using multivariate logistic regression. A total of 1069 incident cases of type 2 diabetes were identified. A list of foods characterizing the dietary pattern differed by sex. Higher dietary pattern scores were associated with an increased risk of type 2 diabetes; ORs (95% CIs) comparing extreme quintiles were 1.53 (1.12–2.09; p for trend = 0.008) for men and 1.33 (0.95–1.86; p for trend = 0.011) for women. Our study suggests the evidence that dietary patterns associated with low levels of TG/HDL-C ratio may have the potential to reduce the burden of type 2 diabetes.


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