scholarly journals Disulfiram Ethanol Reaction with Alcohol-Based Hand Sanitizer: An Exploratory Study

2020 ◽  
Vol 56 (1) ◽  
pp. 42-46
Author(s):  
Abhishek Ghosh ◽  
Tathagata Mahintamani ◽  
Y P S Balhara ◽  
Fazl E Roub ◽  
Debashish Basu ◽  
...  

Abstract Aims We conducted a cross-sectional survey to estimate the prevalence and clinical manifestation of disulfiram ethanol reaction (DER) and isopropanol toxicity (IT) in patients with alcohol use disorders, on disulfiram. Alcohol-based hand rub contains either ethanol or isopropanol or both. COVID-19 pandemic has led to wide scale usage of sanitizers. Patients with alcohol use disorders, on disulfiram, might experience disulfiram ethanol like reactions with alcohol-based sanitizers. Methods We telephonically contacted 339 patients, prescribed disulfiram between January 2014 and March 2020. The assessment pertained to the last 3 months (i.e. third week of March to third week of June 2020). Result The sample consisted of middle-aged men with a mean 16 years of alcohol dependence. Among the 82 (24%) patients adherent to disulfiram, 42 (12.3%) were using alcohol-based hand rubs. Out of these, a total of eight patients (19%; 95% CI 9–33) had features suggestive of DER; four of whom also had features indicative of IT. Five patients (62.5%) had mild and self-limiting symptoms. Severe systemic reactions were experienced by three (37.5%). Severe reactions were observed with exposure to sanitizers in greater amounts, on moist skin or through inhalation. Conclusion Patients on disulfiram should be advised to use alternate methods of hand hygiene.

2015 ◽  
Vol 4 (2) ◽  
pp. 151-158
Author(s):  
Keqin Jia ◽  
Judy Fleiter ◽  
Mark King ◽  
Mary Sheehan ◽  
Wenjun Ma ◽  
...  

Jia, K., Fleiter, J., King, M., Sheehan, M., Ma, W., & Zhang, J. (2015). Knowledge and behaviors of drunk-driving offenders in Guangzhou, China. The International Journal Of Alcohol And Drug Research, 4(2), 151-158. doi:http://dx.doi.org/10.7895/ijadr.v4i2.203Aims: To better understand the knowledge and behaviors of drunk-driving offenders relating to alcohol use and driving in thecontext of recently amended Chinese legislation, and to investigate the involvement of alcohol-use disorders.Design: The study was a cross-sectional survey conducted in 2012.Setting and participants: Data were collected at a local jail and 101 participants were recruited while in detention.Measures: Questionnaire items examined demographic characteristics as well as practices and knowledge relating to alcohol useand driving. The Alcohol Use Disorders Identification Test (AUDIT) was used to assess hazardous drinking levels.Findings: Knowledge about the two legal limits for “drink driving” and for “drunk driving” was low, at 28.3% and 41.4%,respectively. AUDIT scores indicated that a substantial proportion of the offenders had high levels of alcohol-use disorders.Higher AUDIT scores were found among the least experienced drivers, those who lacked knowledge about the legal limits, andrecidivist drunk drivers.Conclusions: Limited awareness of legal alcohol limits might contribute to offending; high AUDIT scores suggest thathazardous drinking levels may also contribute. This study provides important information to assist in refining communityeducation and prevention efforts.


2015 ◽  
Vol 4 (2) ◽  
pp. 151-158 ◽  
Author(s):  
Keqin Jia ◽  
Judy Fleiter ◽  
Mark King ◽  
Mary Sheehan ◽  
Wenjun Ma ◽  
...  

Jia, K., Fleiter, J., King, M., Sheehan, M., Ma, W., & Zhang, J. (2015). Knowledge and behaviors of drunk-driving offenders in Guangzhou, China. The International Journal Of Alcohol And Drug Research, 4(2), 151-158. doi:http://dx.doi.org/10.7895/ijadr.v4i2.203Aims: To better understand the knowledge and behaviors of drunk-driving offenders relating to alcohol use and driving in thecontext of recently amended Chinese legislation, and to investigate the involvement of alcohol-use disorders.Design: The study was a cross-sectional survey conducted in 2012.Setting and participants: Data were collected at a local jail and 101 participants were recruited while in detention.Measures: Questionnaire items examined demographic characteristics as well as practices and knowledge relating to alcohol useand driving. The Alcohol Use Disorders Identification Test (AUDIT) was used to assess hazardous drinking levels.Findings: Knowledge about the two legal limits for “drink driving” and for “drunk driving” was low, at 28.3% and 41.4%,respectively. AUDIT scores indicated that a substantial proportion of the offenders had high levels of alcohol-use disorders.Higher AUDIT scores were found among the least experienced drivers, those who lacked knowledge about the legal limits, andrecidivist drunk drivers.Conclusions: Limited awareness of legal alcohol limits might contribute to offending; high AUDIT scores suggest thathazardous drinking levels may also contribute. This study provides important information to assist in refining communityeducation and prevention efforts.


2019 ◽  
Vol 15 (4) ◽  
pp. 306-319
Author(s):  
Deivi Gaitan ◽  
Valerie Daw Tin Shwe ◽  
Predrag Bajcevic ◽  
Anita Gagnon

Purpose The purpose of this paper is to determine the prevalence of Alcohol Use Disorders (AUDs) among Myanmar male migrant workers (> 15 years) living in Mae Sot, Thailand, and their patterns of drinking. Design/methodology/approach A cross-sectional survey was administered to 512 participants to measure AUDs and drinking patterns. ANOVA and χ2 analyses were performed to assess demographic differences between abstainers, harmful and hazardous drinkers (HHDs) (those showing signs of AUDs) and non-harmful drinkers. Findings Results showed that 12.3 percent of male Myanmar migrants were HHDs, a rate only slightly higher than in Thai men (9.1 percent), but much higher than in men still living in Myanmar (2.7 percent) (WHO, 2014). Also, 19 percent of alcohol-consuming Myanmar male migrant workers reported patterns of heavy episodic drinking, which is markedly higher than in alcohol-consuming Thai (4.7 percent) and Myanmar men (1.5 percent) (WHO, 2014). Originality/value Given the health risks associated with AUDs and heavy episodic drinking, the findings of this study suggest a need for appropriate alcohol-related health education and intervention for Myanmar male migrant workers.


2020 ◽  
Vol 10 (03) ◽  
pp. 114-126
Author(s):  
Kingsley Mayowa Okonoda ◽  
Bawo Onesirosan James ◽  
Christopher Goson Piwuna ◽  
Esther Awazzi Envuladu

Author(s):  
Hashim A. Mahdi ◽  
Hamza M. Assaggaf ◽  
Mohammad Alfelali ◽  
Omar B. Ahmed ◽  
Radi Alsafi ◽  
...  

This study aimed to assess hand hygiene knowledge, perception, and practices of visitors to the Prophet’s Mosque in Al Madinah City, Saudi Arabia. Using a self-administered electronic questionnaire, a cross-sectional survey was conducted among domestic residents, who visited the mosque between 31 July and 3 August 2020. Participants’ demographic data, hand hygiene knowledge, perception, and practices were collected. Four hundred participants aged 18–65 (median 36) years completed the survey, of which 215 (53.8%) were female. The visitors’ mean knowledge score about hand hygiene was 6.4 (± standard deviation (SD) 1.35) of total 12. Most participants (392, 98%) were aware of the role of hand hygiene in preventing Coronavirus Disease 2019 (COVID-19); nevertheless, 384 (96%) said hand hygiene lowers body immunity and 316 (79%) thought <60% alcohol is sufficient for hand disinfection. Males had a higher knowledge score than females (6.46 (±1.41) vs. 6.14 (±1.27), p = 0.02) and, visitors who had no formal education scored higher than those with post-graduate education (6.88 (±1.45) vs 5.73 (±1.12), p = 0.01). Washing hands with soap and water was the predominant method practiced after a meal (365, 91.7%), after toilet visit (354, 88.5%), after touching a surface (262, 65.7%), after waste disposal (332, 83.2%), and when hands were visibly dirty (357, 89.5%). Al Madinah visitors had moderate knowledge about hand hygiene, but demonstrated some knowledge gaps and negligence in practice that are crucial to curb the spread of COVID-19.


Author(s):  
Demeke Demilew ◽  
Berhanu Boru ◽  
Getachew Tesfaw ◽  
Habtamu Kerebih ◽  
Endalamaw Salelew

Abstract Background Alcohol use disorder increase the risk of physical harm, mental or social consequences for patients and others in the community. Studies on alcohol use disorder and associated factors among medical and surgical outpatients in Ethiopia are limited. Therefore, this study is meant to provide essential data on alcohol use disorder and associated factors among alcohol user medical and surgical outpatients to intervene in the future. Methods An institution-based cross-sectional study was conducted by using the systematic random sampling technique. Alcohol use disorders were assessed using the World Health Organization’s 10-item Alcohol Use Disorder Identification Test (AUDIT) questionnaire. Bivariate and multivariate logistic regression analyses were performed, a P-value less than 0.05 were considered statistically significant in the multivariate analysis and the strength of association was measured at a 95% confidence interval. Results The prevalence of alcohol use disorder was 34.5% with a 95% CI (29.20, 39.80) among study participants. In the multivariate logistic regression analysis, male sex (AOR = 3.33, 95%CI: 1.40, 7.93), history of mental illness (AOR = 2.68, 95%CI: 1.12, 6.38), drinking for relaxation (AOR = 1.88, 95%CI: 1.02, 3.48) and history of lifetime tobacco use (AOR = 5.64, 95%CI: 1.95, 16.29) were factors significantly associated with alcohol use disorder. Conclusion The prevalence of alcohol use disorders among medical and surgical outpatients was found to be high. Male sex, history of mental illness, alcohol use for relaxation and lifetime cigarette smoking need more attention during the assessment of patients in the medical and surgical outpatient departments.


2015 ◽  
Vol 11 (2) ◽  
pp. 152-157
Author(s):  
A Risal ◽  
H Tharoor

Background Alcohol Dependence exists in different spectrums at different settings and associated with various medical morbidities, disability and health care utilization costs. Objectives To study the drinking patterns, alcohol use disorders and alcohol related medical morbidities in patients diagnosed with Alcohol Dependence Syndrome (ADS) and attending out / in-patient psychiatry services at secondary and tertiary care centre. Methods A cross-sectional comparative study was done among the patients diagnosed with ADS attending psychiatry services at District hospital, Udupi and Kasturba Hospital, Manipal. Serial sampling was done. Patients having any other psychiatric illnesses were excluded. The two groups were compared in relation to socio-demographic variables, drinking related variables, patterns of drinking and alcohol related medical morbidities identified. Results Significant differences in some socio-demographic parameters among the patients from the two different treatment centers were found with secondary level hospital (N=50) having more illiterate, laborers and below the poverty line population in comparison to the tertiary level hospital (N=75). Maximum frequency of gastro-intestinal morbidities was seen in both the hospital population, irrespective of the patterns of drinking. Conclusion Alcohol use disorders and alcohol related medical morbidities show some variations in their presentations in the different treatment centers. DOI: http://dx.doi.org/10.3126/kumj.v11i2.12492 Kathmandu University Medical Journal Vol.11(2) 2013: 152-157


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