scholarly journals A critical review of the treatment options available for obstructive sleep apnoea: an overview of the current literature available on treatment methods for obstructive sleep apnoea and future research directions

2014 ◽  
Vol 7 (0) ◽  
pp. hzu011-hzu011
Author(s):  
A. J. Booth ◽  
Y. Djavadkhani ◽  
N. S. Marshall
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Current Literature ◽  
Critical Review ◽  
Treatment Options ◽  
Sleep Apnoea ◽  
Future Research ◽  
Research Directions ◽  
Treatment Methods ◽  
Obstructive Sleep ◽  
Future Research Directions

scholarly journals Challenges and perspectives in obstructive sleep apnoea

2018 ◽  
Vol 52 (3) ◽  
pp. 1702616 ◽  
Author(s):  
Winfried Randerath ◽  
Claudio L. Bassetti ◽  
Maria R. Bonsignore ◽  
Ramon Farre ◽  
Luigi Ferini-Strambi ◽  
...  
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Sleep Stage ◽  
Treatment Options ◽  
Sleep Apnoea ◽  
Future Research ◽  
Poor Correlation ◽  
Pressure Therapy ◽  
Obstructive Sleep ◽  
Underlying Mechanisms ◽  
The Impact

Obstructive sleep apnoea (OSA) is a major challenge for physicians and healthcare systems throughout the world. The high prevalence and the impact on daily life of OSA oblige clinicians to offer effective and acceptable treatment options. However, recent evidence has raised questions about the benefits of positive airway pressure therapy in ameliorating comorbidities.An international expert group considered the current state of knowledge based on the most relevant publications in the previous 5 years, discussed the current challenges in the field, and proposed topics for future research on epidemiology, phenotyping, underlying mechanisms, prognostic implications and optimal treatment of patients with OSA.The group concluded that a revision to the diagnostic criteria for OSA is required to include factors that reflect different clinical and pathophysiological phenotypes and relevant comorbidities (e.g.nondipping nocturnal blood pressure). Furthermore, current severity thresholds require revision to reflect factors such as the disparity in the apnoea–hypopnoea index (AHI) between polysomnography and sleep studies that do not include sleep stage measurements, in addition to the poor correlation between AHI and daytime symptoms such as sleepiness. Management decisions should be linked to the underlying phenotype and consider outcomes beyond AHI.

Obstructive sleep apnoea and schizophrenia: a primer for psychiatrists

2011 ◽  
Vol 23 (5) ◽  
pp. 201-209 ◽  
Author(s):  
Abdulkader Alam ◽  
Kadiamada Nanaiah Roy Chengappa
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Daytime Sleepiness ◽  
Treatment Options ◽  
Clinical Manifestations ◽  
Sleep Apnoea ◽  
Diagnosis And Treatment ◽  
Adverse Health Outcomes ◽  
Ovid Medline ◽  
Obstructive Sleep ◽  
Osa Treatment

Alam A, Chengappa KNR. Obstructive sleep apnoea and schizophrenia: a primer for psychiatristsObjective:The main objective of this review is to improve psychiatric clinician awareness of obstructive sleep apnoea (OSA) and its potential consequences in patients with schizophrenia. This article will also discuss the diagnosis and treatment options for OSA while considering the significant role psychiatrists can play in facilitating the diagnosis and treatment of OSA.Data sources:Ovid, Medline and PsychInfo databases were searched for articles between 1960 and 2010. Search terms used wereSleep apnoeaorapnoeaandschizophreniaorpsychosis. The number of articles retrieved was 38. Articles were carefully reviewed for any data pertinent to OSA in patients with schizophrenia.Conclusions:OSA is a common disorder that is frequently unrecognised. As a chronic breathing condition, OSA is associated with adverse health outcomes and high mortality. OSA may co-occur with schizophrenia or evolve over time, especially with weight gain. The diagnosis should be considered whenever a patient presents with risk factors or clinical manifestations that are highly suggestive of OSA. Those who report snoring, daytime sleepiness and are obese or have a large neck circumference should be considered for an OSA diagnosis. Appropriate diagnosis and treatment of OSA can reduce daytime sleepiness, improve cardiovascular and other medical conditions, as well as reduce mortality. Psychiatrists can play very important role in suspecting OSA in their patients and making the initial referral. Furthermore, behavioural management, especially promoting weight loss and smoking cessation, are effective components of OSA treatment that psychiatrists are positioned to facilitate with their patients.

scholarly journals Influence of Fe2+-catalysed iron oxide recrystallization on metal cycling

2012 ◽  
Vol 40 (6) ◽  
pp. 1191-1197 ◽  
Author(s):  
Drew E. Latta ◽  
Christopher A. Gorski ◽  
Michelle M. Scherer
Keyword(s):  
Iron Oxide ◽  
Experimental Evidence ◽  
Recent Work ◽  
Iron Oxides ◽  
Current Literature ◽  
Future Research ◽  
Research Directions ◽  
Metal Cycling ◽  
Future Research Directions ◽  
Metal Incorporation

Recent work has indicated that iron (oxyhydr-)oxides are capable of structurally incorporating and releasing metals and nutrients as a result of Fe2+-induced iron oxide recrystallization. In the present paper, we briefly review the current literature examining the mechanisms by which iron oxides recrystallize and summarize how recrystallization affects metal incorporation and release. We also provide new experimental evidence for the Fe2+-induced release of structural manganese from manganese-doped goethite. Currently, the exact mechanism(s) for Fe2+-induced recrystallization remain elusive, although they are likely to be both oxide-and metal-dependent. We conclude by discussing some future research directions for Fe2+-catalysed iron oxide recrystallization.

Parental Warmth and Hostility as Related to Sex Differences in Children's Achievement Orientation

1977 ◽  
Vol 1 (3) ◽  
pp. 229-246 ◽  
Author(s):  
Rebecca Oxford Manley
Keyword(s):  
Sex Differences ◽  
Critical Review ◽  
Future Research ◽  
Parental Warmth ◽  
Achievement Orientation ◽  
Research Directions ◽  
Children's Achievement ◽  
Future Research Directions ◽  
Relationship Of ◽  
The Relationship

This article is a critical review of studies concerning the relationship of parental warmth and hostility to sex-related differences in children's achievement orientation. Parental warmth seemed to operate differently upon girls' and boys' achievement orientation in most of the studies cited. Moderate but not high maternal warmth and even slight hostility were related to strong achievement∗ orientation in girls, while high maternal nurturance and affection were associated with strong achievement orientation in boys. However, the article warns against assuming a simple causal relationship between parental warmth and sex-related differences in children's achievement orientation. Achievement theories, two main parental dimensions, and future research directions are also discussed.

Obstructive sleep apnoea

2021 ◽  
pp. 335-344
Author(s):  
Terry Robinson ◽  
Jane Scullion
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Nursing Care ◽  
Treatment Options ◽  
Signs And Symptoms ◽  
Diagnostic Procedures ◽  
Sleep Apnoea ◽  
Differential Diagnoses ◽  
Treatment Prevalence ◽  
Obstructive Sleep ◽  
Psychosocial History

This chapter covers the causes, signs, and symptoms of obstructive sleep apnoea (OSA). It explains the process of diagnosis, from a history, medications, family, and psychosocial history, occupation, and diagnostic procedures. Differential diagnoses that should be excluded are listed. The prevalence of OSA is estimated to be around 4% of the population. It is quite a common disorder, although this figure may be an underestimate as many people may not seek treatment. Prevalence figures also vary according to the chosen threshold for defining a significant sleep abnormality and symptoms. Treatment options are also outlined, and the specific aspects of nursing care are listed.

scholarly journals Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment

2017 ◽  
Vol 26 (146) ◽  
pp. 170069 ◽  
Author(s):  
Maria R. Bonsignore ◽  
Monique C. Suarez Giron ◽  
Oreste Marrone ◽  
Alessandra Castrogiovanni ◽  
Josep M. Montserrat
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Treatment Options ◽  
Personalised Medicine ◽  
Upper Airway ◽  
Sleep Apnoea ◽  
Lifestyle Changes ◽  
Mandibular Advancement ◽  
Considerable Proportion ◽  
Special Focus ◽  
Obstructive Sleep

In all fields of medicine, major efforts are currently dedicated to improve the clinical, physiological and therapeutic understanding of disease, and obstructive sleep apnoea (OSA) is no exception. The personalised medicine approach is relevant for OSA, given its complex pathophysiology and variable clinical presentation, the interactions with comorbid conditions and its possible contribution to poor outcomes. Treatment with continuous positive airway pressure (CPAP) is effective, but CPAP is poorly tolerated or not accepted in a considerable proportion of OSA patients. This review summarises the available studies on the physiological phenotypes of upper airway response to obstruction during sleep, and the clinical presentations of OSA (phenotypes and clusters) with a special focus on our changing attitudes towards approaches to treatment. Such major efforts are likely to change and expand treatment options for OSA beyond the most common current choices (i.e. CPAP, mandibular advancement devices, positional treatment, lifestyle changes or upper airway surgery). More importantly, treatment for OSA may become more effective, being tailored to each patient's need.

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