scholarly journals A New Predictive Equation for Estimating Body Weight in Cirrhotic Patients With Refractory Ascites

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 868-868
Author(s):  
Bruna Alves ◽  
Moiséli da Cruz ◽  
Antonio Lopes ◽  
Camila Saueressig ◽  
Valesca Dall'Alba
Keyword(s):  
High Reliability ◽  
Intraclass Correlation ◽  
Dry Weight ◽  
Joint Effect ◽  
Prediction Equation ◽  
Cross Sectional Study ◽  
Refractory Ascites ◽  
Decompensated Cirrhosis ◽  
Cross Sectional ◽  
The Mean

Abstract Objectives This study aims to develop a new prediction equation to estimate the dry weight (DW) of patients with refractory cirrhotic ascites since there is a lack of evidence to substantiate the current values used to adjust the wet weight in these patients. Methods Cross-sectional study, that included patients with decompensated cirrhosis undergoing large-volume paracentesis. Height (H) was measured and weight, immediately before and after paracentesis. For the prediction of DW, a linear regression model was performed using as predictor variables: gender, H, and pre-paracentesis weight (preW), as response variable: post-paracentesis weight (postW). Three-way interaction was used to test the joint effect of these predictors. The capacity of this model to predict the postW was evaluated by comparing it with the currently used predictions through the intraclass correlation coefficient (ICC) and the mean square error (MSE). Results Twenty patients were included, 16 were male. Moderate ascites was the most prevalent grade (n = 18). The mean (range) of ascitic fluid drained was 6.6 (0.45 – 16.0) L, and the difference of Wpre and Wpost was −6.8 (−0.7 – −15.7) kg. The prediction equation developed for estimating DW in male is: DW = −11.4 + 1.2 * Wpre + 0.125 * H −0.002 * Wpre * H, and in female: DW = −40.6 + 1.2 * Wpre + 0.331 * H −0.030 * Wpre * H. ICC values showed that all predictions measures were strongly correlated (r > 0.95). In comparison with current predictions, our model showed the highest ICC (r = 0.97) and the lowest MSE ( = 7.70), comparing with the current predictions (MSE = 18.63, when the preW is adjusted from absolute values and MSE = 12.75 when adjusted from percentage values), indicating more accurate prediction. Conclusions This new prediction equation showed high reliability as a weight adjustment tool for patients with refractory cirrhotic ascites. Further research is required to validate this prediction equation. Funding Sources Fundo de Incentivo à Pesquisa e Eventos (FIPE) from Hospital de Clínicas de Porto Alegre and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) from Ministry of Education of Brazil.

scholarly journals A Quantitative Comparison of Multispectral Refraction Topography and Autorefractometer in Young Adults

2021 ◽  
Vol 8 ◽  
Author(s):  
Yunru Liao ◽  
Zhenlan Yang ◽  
Zijing Li ◽  
Rui Zeng ◽  
Jing Wang ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Pearson Correlation ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
High Agreement ◽  
Intraclass Correlation Coefficients ◽  
Repeatability And Reproducibility ◽  
The Mean

Purpose: Purpose of this study is to evaluate the measuring consistency of central refraction between multispectral refraction topography (MRT) and autorefractometry.Methods: This was a descriptive cross-sectional study including subjects in Sun Yat-sen Memorial Hospital from September 1, 2020, to December 31, 2020, ages 20 to 35 years with a best corrected visual acuity of 20/20 or better. All patients underwent cycloplegia, and the refractive status was estimated with autorefractometer, experienced optometrist and MRT. We analyzed the central refraction of the autorefractometer and MRT. The repeatability and reproducibility of values measured using both devices were evaluated using intraclass correlation coefficients (ICCs).Results: A total of 145 subjects ages 20 to 35 (290 eyes) were enrolled. The mean central refraction of the autorefractometer was −4.69 ± 2.64 diopters (D) (range −9.50 to +4.75 D), while the mean central refraction of MRT was −4.49 ± 2.61 diopters (D) (range −8.79 to +5.02 D). Pearson correlation analysis revealed a high correlation between the two devices. The intraclass correlation coefficient (ICC) also showed high agreement. The intrarater and interrater ICC values of central refraction were more than 0.90 in both devices and conditions. At the same time, the mean central refraction of experienced optometrist was −4.74 ± 2.66 diopters (D) (range −9.50 to +4.75D). The intra-class correlation coefficient of central refraction measured by MRT and subjective refraction was 0.939.Conclusions: Results revealed that autorefractometry, experienced optometrist and MRT show high agreement in measuring central refraction. MRT could provide a potential objective method to assess peripheral refraction.

scholarly journals Development and evaluation of a diet quality screener to assess adherence to the Dutch food-based dietary guidelines

2021 ◽  
pp. 1-28
Author(s):  
Mariëlle G de Rijk ◽  
Anne I Slotegraaf ◽  
Elske M Brouwer-Brolsma ◽  
Corine WM Perenboom ◽  
Edith JM Feskens ◽  
...  
Keyword(s):  
Diet Quality ◽  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Dietary Guidelines ◽  
Full Length ◽  
Cross Sectional ◽  
Maximum Score ◽  
The Mean ◽  
Excellent Reproducibility

Abstract The Eetscore FFQ was developed to score the Dutch Healthy Diet index 2015 (DHD2015-index) representing the Dutch food-based dietary guidelines of 2015. This paper describes the development of the Eetscore FFQ, a short screener assessing diet quality, examines associations between diet quality and participants’ characteristics, and evaluates the relative validity and reproducibility of the Eetscore FFQ in a cross-sectional study with Dutch adults. The study sample consisted of 751 participants, aged 19-91 y, recruited from the EetMeetWeet research panel. The mean DHD2015-index score based on the Eetscore FFQ of the total sample was 111 (SD 17.5) out of a maximum score of 160 points and was significantly higher in women than in men, positively associated with age and education level, and inversely associated with BMI. The Kendall’s tau-b coefficient of the DHD2015- index between the Eetscore FFQ and the full-length FFQ (on average 1.7-month interval, n=565) was 0.51 (95% CI 0.47, 0.55), indicating an acceptable ranking ability. The intraclass correlation coefficient (ICC) between DHD2015-index scores derived from two repeated Eetscore FFQs (on average 3.8-month interval, n=343) was 0.91 (95% CI: 0.89, 0.93) suggesting a very good reproducibility. In conclusion, the Eetscore FFQ was considered acceptable in ranking participants according to their diet quality compared with the full-length FFQ and showed good to excellent reproducibility.

scholarly journals Designing and psychometric evaluation of Stretching Exercise Influencing Scale (SEIS)

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e026565
Author(s):  
Mohammad Hossien Delshad ◽  
Sedigheh Sadat Tavafian ◽  
Anoshirvan Kazemnejad
Keyword(s):  
Psychometric Properties ◽  
Intraclass Correlation ◽  
Psychometric Evaluation ◽  
Cross Sectional Study ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Valid Instrument ◽  
Good Internal Consistency ◽  
The Mean ◽  
Office Employees

ObjectiveThe lack of reliable and valid tools for assessing the factors that influence stretching exercises (SEs) among Iranian office employees is obvious. This study aimed to design and evaluate psychometric properties of this instrument.DesignCross-sectional study of psychometric properties.SettingData were gathered from May to September 2017.ParticipantsParticipants were 420 office employees who were working in 10 health centres affiliated to the Shahid Beheshti University of Medical Sciences in Tehran, Iran.Primary outcome measuresThe instrument was designed on the basis of the constructs of the health promotion model (HPM) and extant literature. Exploratory factor analysis (EFA), Cronbach’s α and intraclass correlation coefficient (ICC) were employed to check the scale’s psychometric properties.ResultsIn total, 420 questionnaires were completed. The mean age of the office employees was 37.1±8.03 years. Among the 86 items, 77 items had significant item-to-total correlations (p<0.05). The results showed good internal consistency and reliability for the whole questionnaire and each domain. EFA results confirmed 53.32% of the total variance of the items yielded in 11 subscales. The ICC was acceptable (0.78, 95% CI 0.70 to 0.88).ConclusionsThe Stretching Exercise Influencing Scale (SEIS) can be a reliable and valid instrument for measuring the factors that influence SEs among office employees.Trial registrationIRCT20160824295512N1

scholarly journals P0160HOW TO MANAGE INTRADIALYTIC HYPERTENSION?

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Ramia BENHAMOU ◽  
Hajar ELASSAS ◽  
Meriem Chettati ◽  
Wafaa Fadili ◽  
Inass Laouad
Keyword(s):  
Dry Weight ◽  
Cross Sectional Study ◽  
Antihypertensive Medications ◽  
Cross Sectional ◽  
Female Predominance ◽  
High Calcium ◽  
Great Solution ◽  
The Mean ◽  
Group 1

Abstract Background and Aims Hypertension in subjects on long term dialysis is frequent. Intradialytic hypertension affects up to 20% of hemodialysis patients and occurs more frequently in patients who are older, have lower dry weights, are prescribed more antihypertensive medications. Elevated BP detected by home or ambulatory BP monitoring is clearly associated with shorter survival. Method We realized a cross sectional study in two hemodialysis center patients during october 2019. We compared two groups of patients: group 1 with HTA (HTA+) and the second without (HTA-). Prevalence of hypertension intra dialysis (increase in systolic BP &gt; 15mmHg during dialysis) was determined by blood pressure recordings every thirty minutes during hemodialysis. We collect information about prescription patients (bolus dose of IV nicardipine or administration of captopril orally) after HTA inicident. We collected and analyzed datas of 1476 hemodialysis sessions for 123 patients. Results The mean age of your patients was 46 ± 26,3 years with a female predominance. The mean duration of hemodialysis was 9,8 years. The initial nephropathy was hypertensive in 14,6%. 44,7% (n=55) patients used at least one antihypertensive treatment (HTA+ group), in 72,7% calcic inhibitor. Hypertension crisis in HTA+ group was higher than HTA- group, respectively 37,9% and 4,7% (p=0,0002). Concerning HTA+ group, in 9,35% of cases patients receveid IV bolus of nicardipine, 7,9% captopril and 17,9% of cases have not receveid any antihypertensive medication. In HTA- group they receveid IV nicardipine on only 2,5% cases and no drugs in half of all cases. Patients who were older and receive erythropoietin-stimulating agents were more likely to exhibit an increase in SPB despite similar amounts of ultrafiltration in each groups. It appears HTA- group had better control of hypertension crisis in 77,5% versus 65,5% in HTA+ group, at 20minutes of crisis (p= 0,004). Administration of captopril in the both group allowed better control of hypertension 90% (HTA+ group) and 84,2%(HTA- group). Hypertension crisis was more controlled in group with high ultrafiltration rate with administration of captopril . Conclusion Use of ACE inhibitors during dialysis to manage hypertension crisis appears a great solution and confirm hypothesis of activation of the renin–angiotensin–aldosterone system. Treatment of intradialytic hypertension may include careful attention to dry weight, avoidance of dialyzable antihypertensive medications, limiting the use of high calcium dialysate, achieving adequate sodium solute removal during hemodialysis, and using medications which inhibit the rennin-angiotensin-aldosterone system or which lower endothelin 1.

scholarly journals Comparing School-Aged Refraction Measurements Using the 2WIN-S Portable Refractor in Relation to Cycloplegic Retinoscopy: A Cross-Sectional Study

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Ziming Liu ◽  
Emmanuel Eric Pazo ◽  
Hong Ye ◽  
Cui Yu ◽  
Ling Xu ◽  
...  
Keyword(s):  
Gold Standard ◽  
Intraclass Correlation ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Spherical Equivalent ◽  
Sectional Study ◽  
Altman Analysis ◽  
Cross Sectional ◽  
Bland Altman Analysis ◽  
The Mean

Purpose. To assess the repeatability and agreement of refractive measurements using 2WIN-S photoscreening with the gold-standard cycloplegic retinoscope refraction. Design. Single centre, cross-sectional study. Methods. Spherical, cylindrical, axis, and spherical equivalent of 194 bilateral eyes of 97 children were assessed using a retinoscope and 2WIN-S. One week later, another operator repeated the 2WIN-S measurements. The primary outcome measures were to assess the repeatability and agreement between spherical equivalent, J0, and J45 readings of 2WIN-S. The repeatability of measurements was assessed by the within-subject standard deviation (2.77 Sw) and intraclass correlation coefficient (ICC). The agreement between devices was assessed using 95% limits of agreement. The extent of the agreement between cycloplegic retinoscopy and noncycloplegic 2WIN-S measurements was assessed using Bland–Altman analysis. Results. The mean age ± SD was 10.3 ± 2.46 year (range, 4–14 years). The sphere, cylinder, and spherical equivalent measurements were found to be consistent with both apparatus (r value >0.86). ICC for SE, J0, and J45 was 0.900, 0.666, and 0.639, respectively; Sw for SE, J0, and J45 was 0.61D, 0.30D, and 0.31D, respectively; Bland–Altman analysis of retinoscopy with cycloplegia and 2WIN-S for SE was 184/194 (95%) in 95% confidence interval, and the mean value was 0.46. J0 was 184/194 (95%), and the mean value is −0.04. J45 was 181/194 (93%), and the mean value is −0.15. Conclusion. The objective refractive measurement of 2WIN-S had good reliability and high agreement with the gold-standard retinoscopy refraction in children and adolescents. While consistency was observed, it is essential to take into consideration that it is a screening tool.

scholarly journals INTRA- AND INTER-RATER RELIABILITY OF A BIOPHOTOGRAMMETRIC ASSESSMENT PROTOCOL FOR PRETERM INFANTS

2021 ◽  
Vol 39 ◽  
Author(s):  
Juliana Vieira Campos ◽  
Mariana Alves Moreno ◽  
Ricardo de Bastos Silva ◽  
Jessica Neves Quirino da Silva ◽  
Milena Ferreira de Carvalho ◽  
...  
Keyword(s):  
Preterm Infants ◽  
High Reliability ◽  
Intraclass Correlation ◽  
Cross Sectional Study ◽  
Lateral View ◽  
Preterm Neonates ◽  
Cross Sectional ◽  
Rater Reliability ◽  
Assessment Protocol ◽  
Two Stages

ABSTRACT Objective: To measure the intra- and inter-rater reliability of a biophotogrammetric assessment protocol for thoracoabdominal motion in preterm infants. Methods: This is an analytical cross-sectional study. Footage of 40 preterm infants was made in two views (lateral and anterior). The babies were placed in the supine position, with retroverted pelvis and semiflexed knees. Acrylic markers were positioned on surgical tape in eight predetermined anatomical points. We analyzed 4 variables in lateral view and 11 in anterior view (angular and linear) (ImageJ®), divided into two stages: 1. same frames - three blinded evaluators analyzed frames previously selected by the main researcher (inter-rater analysis 1), reviewing these same frames after 15 days (intra-rater analysis 1); 2. different frames - each evaluator selected the frames from the original video and repeated the protocol (inter-rater analysis 2), with a review after 15 days (intra-rater analysis 2). In stage 2, we tested the reliability of the entire process, from image selection to the analysis of variables. Data agreement and reproducibility were obtained by the intraclass correlation coefficient (ICC). Results: Agreement was high, particularly in angular variables (ICC 0.82 to 0.99). Linear variables ranged between very good and excellent in analysis 1 (same frames: ICC 0.64 to 0.99) and analysis 2 (different frames: ICC 0.44 to 0.89). Conclusions: The present study suggests that the proposed protocol for the thoracoabdominal motion analysis of preterm neonates has high reliability.

scholarly journals Morphometric changes correlate with poor psychological outcomes in patients with acromegaly

2016 ◽  
Vol 174 (1) ◽  
pp. 41-50 ◽  
Author(s):  
Syed Ali Imran ◽  
Jitske Tiemensma ◽  
Stephanie M Kaiser ◽  
Michael Vallis ◽  
Steve Doucette ◽  
...  
Keyword(s):  
Intraclass Correlation ◽  
Illness Perception ◽  
Cross Sectional Study ◽  
Psychological Outcomes ◽  
Clinical Tool ◽  
Cross Sectional ◽  
Drawing Test ◽  
Facial Changes ◽  
The Mean ◽  
Physical Changes

Objective:Acromegaly is frequently associated with altered facial appearance at the time of diagnosis. Furthermore, acromegaly is also associated with adverse psychological outcomes. We conducted a single-centre, cross-sectional study comparing patients with growth hormone vs non-functioning pituitary adenomas (NFA) to assess the association between morphometric changes and psychological outcomes and illness perception of patients with acromegaly.Methods:A seven-step scale was developed to grade morphometric changes based on facial photographs. In addition, all patients were asked to draw an image of their own body and an image of what they considered to be an average healthy body and complete seven psychological questionnaires. We recruited 55 consecutive patients in each of the two groups who had undergone surgery with or without radiation therapy (RT).Results:Our data showed that the clinician-rated morphometric scale was highly reliable in assessing facial changes, with 93/99 (Intraclass correlation coefficient (ICC)=0.95 (0.93–0.97)) graded as similar by independent raters. The mean (s.d.) grading for Acro and NFA patients on the clinician-rated morphometric scale were 3.5 (1.3) and 0.41 (0.35) respectively (P<0.0001). A higher clinician-rated morphometric score was also predictive of a poorer score on the drawing test.Conclusions:Our study demonstrates a correlation between physical changes associated with acromegaly and poor psychological outcomes, whereas no such correlation existed with modes of therapy, disease control status, RT, malignancy, initial or recent GH/IGF1 or secondary hormonal deficiency. Our data support the utility of the morphometric scale as a clinical tool for grading facial changes.

scholarly journals Inter-Rater Reliability of Ergonomic Risk Assessment Methods

2019 ◽  
Author(s):  
Atefeh Siahi Ahangar ◽  
Sahebeh Ghanbari ◽  
Majid Hajibabaei ◽  
Mahnaz Saremi ◽  
Narges Azadi ◽  
...  
Keyword(s):  
High Reliability ◽  
Intraclass Correlation ◽  
Video Camera ◽  
Cross Sectional Study ◽  
Risk Level ◽  
Complete Agreement ◽  
Cross Sectional ◽  
Rater Reliability ◽  
Risk Levels ◽  
Kappa Agreement

Background: Musculoskeletal disorders are one of the most common occupational diseases, and in recent years, several methods have been developed to evaluate risk factors for these types of disorders. Methods: In this cross-sectional study, 40 tasks in small industries including carpentry, turning, welding, loading and unloading, and sewing were recorded with a video camera and in the second stage, the postures were reviewed and evaluated by six raters. In total, forty of the worst and most frequent postures were analyzed by self-raters and then, the same risk levels were determined for the six methods and analyzed with correlation and Kappa agreement coefficient tests using SPSS (version 19), and then they were compared with each other using the Intraclass correlation coefficient (ICC). Results: The results revealed the importance of Kappa Coefficient in which it shows the risk level of different method and specified pair method: OCRA/SI =0.25, OCRA/HAL=0.2, SI/HAL= 0.32, SI/ RULA= 0.33, REBA/OCRA = 0.4, QEC/SI= 0.27, QEC/ RULA= 0.23Inter-rater Reliability of the methods was found as follow:ICCOCRA=0.3, ICCSI= 0.67, ICCHAL= 0.8, ICCRULA= 0.85, ICCREBA=0.8, ICCQEC=0.972.Conclusions: The results showed that there was no complete agreement among the methods. This agreement among methods is evaluated from poor to good (0.2-0.4). The ICC showed high reliability in the methods except in the OCRA method.

scholarly journals The Dietary Intake of Patients With Decompensated Cirrhosis Is Less Than the Prescribed Half: It Is Not Enough to Prescribe, It Is Necessary to Monitor

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 50-50
Author(s):  
Camila Saueressig ◽  
Pâmela Kremer Ferreira ◽  
Joana Hoch Glasenapp ◽  
Valesca Dall'Alba
Keyword(s):  
Food Intake ◽  
Dietary Intake ◽  
Protein Intake ◽  
Cross Sectional Study ◽  
Carbohydrate Intake ◽  
Decompensated Cirrhosis ◽  
Rank Test ◽  
Food Record ◽  
Cross Sectional ◽  
The Mean

Abstract Objectives The objective of this study was to compare the prescribed nutrition with dietary intake in hospitalized patients with decompensated cirrhosis. Methods This is a cross-sectional study performed with hospitalized decompensated cirrhotic patients. The individual nutritional requirements were determined through the registered dietitian and the patient's nutrition prescription was checked from the electronic medical records. A one-day food record was applied to all participants, who received prior guidance on how to properly report their meals. Data are expressed as mean ± SD or median [interquartile range]. The student's t-test was used to compare variables with a parametric distribution and the Wilcoxon signed-rank test was used for those with a non-parametric distribution. P &lt; 0.05 was considered statistically significant. Results This study included 94 patients with a mean age of 60.3 ± 9.3 years and 64.8% were men. The main etiology of cirrhosis was hepatitis C (27.6%). Ascites was the most common complication, with a prevalence of 73.4%. The mean energy prescribed and the actual mean dietary intake were 2191.25 ± 295.77 kcal/d (31.25 ± 7.7 kcal/kg/d) and 1289.40 ± 509.71 kcal/d (18.61 ± 7.93 kcal/kg/d), respectively. The actual mean dietary intake was 902.68 ± 475.08 kcal/d less than the energy prescribed, p &lt; 0.001. The median protein prescribed and the actual median protein intake were 94 g/d [88.9–110] (1.4 g/kg/d [1.2–1.7]) and 51.44 g/d [34.79–64.84] (0.7 g/ptn/d [0.5–0.9]), respectively. The actual median protein intake was 48.69 g/d [34.07–64.70] less than the protein prescribed, P &lt; 0.001. The mean carbohydrate prescribed and the actual mean carbohydrate intake were 304.77 ± 80.74 g/d and 179.65 ± 73.62 g/d, respectively. The actual mean carbohydrate intake was 124.57 ± 96.82 less than the carbohydrate prescribed, P &lt; 0.001. Conclusions The results of this study demonstrate that patients with decompensated cirrhosis have inadequate food intake. Encourage eating and monitoring of the daily food intake should be part of the management of these patients and occur throughout hospitalization. Funding Sources This study was supported by a CAPES and FIPE/HCPA scholarship. The sources of funding were not involved in study design; in the collection, analysis, and interpretation of the data.

Reproducibility and validity of an FFQ in the Henan Rural Cohort Study

2019 ◽  
Vol 23 (1) ◽  
pp. 34-40 ◽  
Author(s):  
Yuan Xue ◽  
Kaili Yang ◽  
Bingya Wang ◽  
Chang Liu ◽  
Zhenxing Mao ◽  
...  
Keyword(s):  
Rural Population ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Validity Study ◽  
Food Groups ◽  
Cross Sectional ◽  
Reproducibility Study ◽  
The Mean ◽  
Spearman’S Correlation

AbstractObjective:The present study aimed to evaluate the validity and reproducibility of a thirteen-item FFQ regarding identification of dietary conditions in a rural population in China.Design:A reproducibility study repeated the first FFQ (FFQ1) approximately 4 weeks later (FFQ2). A validity study evaluated the mean of three consecutive 24 h diet recalls as the reference measure.Setting:Cross-sectional study.Participants:Residents of a rural area in Henan Province, which is located in the central region of China.Results:A total of 295 individuals participated in the reproducibility study. In addition, 123 people agreed to participate in the validity study. Spearman’s correlation coefficients between the two FFQ ranged from 0·06 (vegetables) to 0·58 (eggs). Spearman’s correlation coefficients between the two methods of collection ranged from 0·01 for cereal to 0·49 for staple foods. The mean of the intraclass correlation coefficients of the two FFQ (FFQ1 v. FFQ2) was 0·19. Bland–Altman analysis indicated good agreement for most food groups across the range of intake for the two studies.Conclusions:The study demonstrated that our FFQ design could be used as a representative tool to conduct a dietary evaluation of a rural population.

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