An evaluation of kits for measuring thyrotropin in newborns.

1984 ◽  
Vol 30 (11) ◽  
pp. 1854-1856 ◽  
Author(s):  
E A Pierson ◽  
B L Therrell ◽  
S F Franz ◽  
A J Rudenstein ◽  
P E Dziuk
Keyword(s):  
United States ◽  
Filter Paper ◽  
Whole Blood ◽  
The United States ◽  
Medical Systems ◽  
Becton Dickinson ◽  
Screening Programs ◽  
Coefficients Of Variation ◽  
Blood Specimens

Abstract Several commercial radioimmunoassay kits are now marketed specifically for determination of thyrotropin (TSH) from whole-blood specimens collected on filter paper in neonatal screening programs. We have compared five kits in use in such screening programs in the United States. The reagent kits from Becton Dickinson, Neometrics, and Nuclear Medical Systems gave similar satisfactory results. That from Pharmacia was somewhat more difficult to use and gave greater coefficients of variation. Diagnostic Products' kit appeared to perform satisfactorily, but the analytical values obtained were significantly low, which may suggest erroneous calibrator values within the kit.

Effect of lot-to-lot variability in filter paper on the quantification of thyroxin, thyrotropin, and phenylalanine in dried-blood specimens.

1988 ◽  
Vol 34 (1) ◽  
pp. 53-58 ◽  
Author(s):  
W E Slazyk ◽  
D L Phillips ◽  
B L Therrell ◽  
W H Hannon
Keyword(s):  
Filter Paper ◽  
Whole Blood ◽  
Neonatal Screening ◽  
Intact Cell ◽  
High Concentration ◽  
Mean Values ◽  
Screening Programs ◽  
Blood Specimens

Abstract We prepared whole-blood pools to contain various concentrations of phenylalanine (Phe), thyroxin (T4), and thyrotropin (TSH) and applied them to six different lots of Schleicher & Schuell Grade 903 filter paper, two of which represented extremes for serum-absorbancy. Individual measured T4 values showed minimal overlap among all pools for each individual filter-paper lot and for all lots combined, but Phe values overlapped considerably among the high-concentration pools within and among lots. Individual TSH values also showed considerable overlap among the high-concentration pools for all lots combined, but little overlap within each lot. Maximum differences in mean observed values among lots ranged from 6% to 36% for all analytes. Assay results from hemolyzed blood specimens generally were lower than from intact-cell blood specimens for T4 and TSH, but slightly higher for Phe. Maximum among-lot differences in mean values ranged from 13% to 29% for all analytes when each tested lot was used for assay calibration. Lot-to-lot differences in measured values were not strongly related to serum absorbancy values. We conclude that routinely encountered within- and among-lot filter paper variability, as measured by serum-absorbancy, is not alone sufficient to cause gross quantification errors in neonatal screening programs.

IMPROVEMENT OF THE CAMERAL CHECKS PROCESS IN RUSSIA BASED ON FOREIGN EXPERIENCE

2020 ◽  
Author(s):  
Darya Sergeevna Kareva ◽  
◽  
Sevinj Mahmud kyzy Ismailova ◽  
Elena Evgenievna Dozhdva ◽  
◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Foreign Experience ◽  
Correct Determination

The article substantiates the need to reform cameral tax control in Russia based on the experience of the United States. The necessity of introducing into the procedure of cameral control the mechanism of requesting all documents confirming the correct determination of tax obligations is determined. The aim of improving the process of desk audits of control is that the new procedure for conducting audits will reduce the likelihood of tax violations.

Should Screening Programs Be Perfect?

PEDIATRICS ◽  
1983 ◽  
Vol 71 (2) ◽  
pp. 301-301
Author(s):  
PHILIP R. WYATT
Keyword(s):  
United States ◽  
Health Care ◽  
Early Detection ◽  
New England ◽  
Health Care System ◽  
The United States ◽  
Neonatal Hypothyroidism ◽  
Screening Programs ◽  
Care System

To the Editor.— The report of the New England Regional Screening Program1 on neonatal hypothyroidism is a stunning illustration of the vulnerability of screening programs. It is unfortunate that this experience will probably be used as an argument to minimize the input of screening programs in the health care system in the United States. The report illustrates that, in addition to the 2% of the screened population that eluded the program, 14 infants with hypothyroidism escaped the full benefits of early detection and treatment.

scholarly journals The Theory of Wetting, and the Determination of the Wetting Power of Dipping and Spraying Fluids containing a Soap Basis

1915 ◽  
Vol 7 (2) ◽  
pp. 219-239 ◽  
Author(s):  
W. F. Cooper ◽  
W. H. Nuttall
Keyword(s):  
United States ◽  
South Africa ◽  
Active Substance ◽  
Sodium Arsenite ◽  
The United States ◽  
Active Constituent ◽  
Wetting Power ◽  
The Government

The dipping of sheep and cattle, as a means of eradicating ‘scab,’ lice, ticks, etc., and the diseases which it is now known the latter may transmit, has met with such success, that compulsory dipping is now in vogue in most pastoral countries. Where compulsory dipping obtains, there must of necessity be some system of the standardisation of dips. In Queensland and South Africa, the respective Governments issue official formulae from which the stockbreeder can prepare his own dipping fluid. Only such proprietary dips, as are duly recognised by the Government, may be employed. In the United States, the regulations for the sale of proprietary dips are still more stringent. The quantity of active substance, usually sodium arsenite, nicotine or cresylic acid, is defined within very narrow limits. Further, no proprietary dip is now recognised, unless the manufacturer can furnish a ‘Field Tester,’ by means of which the stockbreeder can himself determine, in a simple and fairly trustworthy manner, the percentage of active constituent in his bath.

scholarly journals First Report of Anthracnose Caused by Colletotrichum acutatum on Persimmon Fruit in the United States

Plant Disease ◽  
2010 ◽  
Vol 94 (5) ◽  
pp. 634-634 ◽  
Author(s):  
S. M. Williamson ◽  
T. B. Sutton
Keyword(s):  
United States ◽  
Filter Paper ◽  
The United States ◽  
Grocery Store ◽  
Fruit Rot ◽  
Colletotrichum Acutatum ◽  
Diospyros Kaki ◽  
Japanese Persimmon ◽  
First Report ◽  
Persimmon Fruit

Persimmon trees are important for their fruit as well as their colorful fruit and foliage in the fall. Persimmon fruit (Japanese persimmon, Diospyros kaki cv. Fuyu) were collected in November 2008 from a tree in Windsor, NC, located in the Coastal Plain. Fruit were not symptomatic on the tree but developed dark lesions after harvest. Isolations from six fruit yielded seven isolates of Colletotrichum acutatum J. H. Simmonds. After incubation at 25°C under continuous light for 15 days on potato dextrose agar (PDA), all isolates had gray aerial mycelium, but the inverse sides of the plates of six isolates were maroon and one was beige. Masses of salmon-colored conidia were formed first in the center of the colonies, then were observed scattered across the colonies in older cultures. Conidia were hyaline, one-celled, elliptic with one or both ends pointed, and measured 8.1 to 16.3 × 3.1 to 5 μm. Setae and sclerotia were not observed. There were also dark structures measuring 1 to 10 mm that were partially embedded in the agar that contained conidia. Cultural and conidial characteristics of the isolates were similar to those of C. acutatum (3). PCR amplification was performed with the species-specific primer pair CaInt2/ITS4 (2) and genomic DNA from the original isolates and isolates obtained from inoculated fruit. An amplification product of approximately 490 bp, which is specific for C. acutatum, was observed. To fulfill Koch's postulates, persimmon fruit obtained from the grocery store were surface disinfested with 0.5% sodium hypochlorite and sterile filter paper disks dipped in conidial suspensions (1 × 105 conidia/ml) of two C. acutatum isolates (maroon and beige reverse) or sterile, deionized water were placed on the fruit. Three fruit were inoculated per treatment and the disks were placed on four locations on each fruit. Parafilm was wrapped around the diameter of the fruit to keep the filter paper disks moist and in place. Fruit were placed in moist chambers and incubated at 25°C. After 3 days, the Parafilm was removed and the fruit returned to the moist chambers. Small, dark lesions were observed on fruit inoculated with each isolate of C. acutatum when the filter paper disks were removed. Ten days after inoculation, dark lesions and acervuli with salmon-colored masses of conidia were observed on fruit inoculated with both isolates of C. acutatum and the fruit were soft. After 12 days, there were abundant masses of conidia and the inoculated areas were decayed. Control fruit remained firm and did not develop symptoms. Cultures obtained from the fruit and the conidia produced were typical of the isolates used to inoculate the fruit. C. acutatum has been reported to cause fruit rot on persimmon fruit in New Zealand (1). To our knowledge, this is the first report of C. acutatum on persimmon fruit in the United States. References: (1) R. Lardner et al. Mycol. Res. 103:275, 1999. (2) S. Sreenivasaprasad et al. Plant Pathol. 45:650, 1996. (3) B. C. Sutton. Page 523 in: Coelomycetes. Commonwealth Agricultural Bureaux, Great Britain. 1980.

scholarly journals The Future of Turkey - United States Relations

Jurnal ICMES ◽  
2018 ◽  
Vol 2 (2) ◽  
pp. 179-196
Author(s):  
Firmanda Taufiq
Keyword(s):  
United States ◽  
The United States ◽  
Economic Interests ◽  
The Us ◽  
The Future ◽  
Foreign Policies ◽  
The Government ◽  
The Cold War ◽  
Role Of The Government

Throughout 2018, relations between Turkey and the United States seemed to deteriorate. The leaders of the two countries issued sharp diplomatic statements and the US even imposed economic sanctions on Turkey. This article aims to analyze how the future of relations between Turkey and the United States. Cooperation between the two has a long historical side after the Cold War. Relations between the two countries are based on various interests, both economic, political, military and security interests. The theory used in this study is the theory of national interest. The US has great interests in the Middle East and Turkey is the front-line ally in achieving those interests. However, there are many US foreign policies that ignore the Turkish concern and create tensions between the two countries. On the contrary, Turkey also has considerable economic interests, but the role of the government elite (in this case, President Erdogan) has a significant influence in the determination of Turkish foreign policy. The findings of this study, although it will go through complex challenges and processes, the US and Turkey will continue to maintain their relations.

scholarly journals Ideological foundations of modern political and legal institutional architectonics in Western Europe and the USA

2020 ◽  
pp. 107-118
Author(s):  
N.N. Ravochkin ◽  
◽  
Keyword(s):  
United States ◽  
Western Europe ◽  
The United States ◽  
Close Attention ◽  
Institutional Settings ◽  
The Usa ◽  
Management Institutions

The author examines the ideological foundations of political and legal institutional architectonics in Western Europe and the United States and presents its structure. Close attention is paid to the role of social ideas and the development of these issues in modern scientific directions. The author clarifies the principles of synthesis of ideal and institutional and shows three ways of ideological determination of political and legal institutional settings. The mutually conditioned nature of functioning of the system of ideological frameworks and management institutions is substantiated.

Precise Determination of Longitude in the United States

1957 ◽  
Vol 47 (4) ◽  
pp. 555
Author(s):  
Robert W. Knox
Keyword(s):  
United States ◽  
The United States ◽  
Precise Determination
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