Reference intervals for calcium, phosphate, and alkaline phosphatase as derived on the basis of multichannel-analyzer profiles.

1986 ◽  
Vol 32 (1) ◽  
pp. 76-79 ◽  
Author(s):  
T J Sinton ◽  
D M Cowley ◽  
S J Bryant
Keyword(s):  
Alkaline Phosphatase ◽  
Calcium Phosphate ◽  
Older Patients ◽  
Reference Intervals ◽  
Plasma Calcium ◽  
Test Results ◽  
Abrupt Increase ◽  
Multichannel Analyzer ◽  
The Mean ◽  
The One

Abstract In an attempt to demonstrate a rapid and economical approach to deriving reference intervals, we analyzed data on plasma calcium and phosphate from a multichannel analyzer for more than 20 000 subjects and data on alkaline phosphatase from more than 10 000 subjects. Subjects were selected by the criterion, that their results for constituents other than the one of interest were within current reference intervals. Thus we have been able to include older patients who have diseases that accompany old age, but that do not affect test results. The mean concentrations of calcium and phosphate decreased with increasing age in both sexes, except for an abrupt increase for women about the time of reaching menopause. Similarly, the mean alkaline phosphatase activity increased with age in both sexes, reflecting a skewed frequency distribution. Here also, there was an abrupt increase in the modal value for women near menopause.

scholarly journals Research on Intelligent Compaction Technology of Subgrade Based on Regression Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Ziyi Hou ◽  
Xiao Dang ◽  
Yezhen Yuan ◽  
Bo Tian ◽  
Sili Li
Keyword(s):  
Resilient Modulus ◽  
Single Point ◽  
Mean Value ◽  
Test Results ◽  
Intelligent Compaction ◽  
One Dimensional ◽  
Remote Monitoring System ◽  
The Mean ◽  
The One ◽  
Compaction Degree

A remote monitoring system with the intelligent compaction index CMV as the core is designed and developed to address the shortcomings of traditional subgrade compaction quality evaluation methods. Based on the actual project, the correlation between the CMV and conventional compaction indexes of compaction degree K and dynamic resilient modulus E is investigated by applying the one-dimensional linear regression equation for three types of subgrade fillers, clayey gravel, pulverized gravel, and soil-rock mixed fill, and the scheme of fitting CMV to the mean value of conventional indexes is adopted, which is compared with the scheme of fitting CMV to the single point of conventional indexes in the existing specification. The test results show that the correlation between the CMV and conventional indexes of clayey gravel and pulverized gravel is much stronger than that of soil-rock mixed subgrades, and the correlation coefficient can be significantly improved by fitting CMV to the mean of conventional indexes compared with single-point fitting, which can be considered as a new method for intelligent rolling correlation verification.

scholarly journals Biological sources of variations of tartrate-resistant acid phosphatase 5b in a healthy Japanese population

2021 ◽  
pp. 000456322110039
Author(s):  
Wataru Kikuchi ◽  
Kiyoshi Ichihara ◽  
Kazuo Mori ◽  
Yoshihisa Shimizu
Keyword(s):  
Alkaline Phosphatase ◽  
Inorganic Phosphate ◽  
Bone Markers ◽  
Bone Alkaline Phosphatase ◽  
Reference Intervals ◽  
Tartrate Resistant Acid Phosphatase ◽  
Test Results ◽  
Age Related ◽  
Sources Of Variation ◽  
Biological Sources

Background Tartrate-resistant acid phosphatase 5b (TRACP5b) is a bone resorption marker that is mainly used in clinical management of osteoporosis. For proper interpretations of test results for serum TRACP5b, we explored their biological sources of variation, esp. age-related changes, and associations with other bone-related markers in healthy Japanese adults. Methods During the 2009 East-Southeast Asian multicentre study for determination of reference intervals, 72 major laboratory tests were measured by centralized assays in 3541 well-defined healthy volunteers. The current study included 1980 test results in Japanese subjects for five bone-related markers: TRACP5b, bone alkaline phosphatase, intact parathyroid hormone, calcium and inorganic phosphate. Information on sources of variation, including body mass index, smoking habits and ABO-blood group, were obtained from a health status questionnaire. Results Gender-specific profiles of age-related changes were observed for each parameter. Increased values starting from 40 years of age in females were most prominent for TRACP5b, followed by bone alkaline phosphatase and inorganic phosphate. TRACP5b in males decreased with body mass index, bone alkaline phosphatase and TRACP5b were higher in blood type-O subjects, especially in males. TRACPT5b was closely correlated with bone alkaline phosphatase, and moderately correlated with adjusted calcium and inorganic phosphate, especially in females aged ≥45 years. Reference intervals for each analyte were determined parametrically based on gender and age. Conclusions This study elucidated sources of variation of TRACP5b and related bone markers in healthy Japanese subjects and demonstrated a specific age profile for each marker. These results are of relevance for better clinical usage and interpretations of serum levels of bone markers.

Statistically Significant Efficiency Testing of HEPA Filters

2004 ◽  
Vol 47 (1) ◽  
pp. 101-106 ◽  
Author(s):  
Wenli Wang ◽  
Philip Winters
Keyword(s):  
High Efficiency ◽  
Test System ◽  
Test Results ◽  
Upper Limits ◽  
Efficiency Performance ◽  
Measured Efficiency ◽  
The Mean ◽  
Particle Counts ◽  
The One ◽  
Time Required

High Efficiency Particulate Air (HEPA) filter manufacturers must ensure the accuracy of efficiency testing for these filters and, at the same time, keep productivity at a reasonable level. This study describes tests conducted to determine the minimum time required to provide statistically significant efficiencies of HEPA filters using a test system currently in use of HEPA filter production. The test results of over 300 HEPA filters were analyzed in this study. The approaches in IEST RP-CC-007.1: Testing ULPA Filters for statistical analysis of particle counts were followed. A Poisson distribution was used to describe the variations and to calculate the lower and upper limits of measured counts at 95% confidence level. This study shows that 90 seconds is sufficient for this test system to determine whether a HEPA filter has an efficiency of 99.990% or higher at 95% confidence. Longer tests will cause the mean measured efficiency to approach the filter's true efficiency and also narrow the confidence interval. However, challenging HEPA filters made of glass fiber media with oil aerosols for up to one hour does not significantly change the filter's true efficiency performance. The preferred approach for a new test system is to use software that calculates the confidence limits of filter efficiency after each sampling cycle and determines whether to continue testing. For an existing system without this type of program (such as the one evaluated in this study), analysis is necessary to make sure the HEPA filters are challenged with enough aerosol particles.

EFFECT OF THYROCALCITONIN ON ALKALINE PHOSPHATASE AND PYROPHOSPHATASE IN RAT TIBIA, KIDNEY AND INTESTINE

1972 ◽  
Vol 70 (4) ◽  
pp. 676-682 ◽  
Author(s):  
Cipora Streifler ◽  
Arie Orenstein ◽  
Arieh Harell
Keyword(s):  
Alkaline Phosphatase ◽  
Kidney Tissue ◽  
Plasma Calcium ◽  
Inorganic Pyrophosphatase ◽  
Rat Tibia ◽  
Rat Bone

ABSTRACT The influence of thyrocalcitonin (TCT) on the enzymes alkaline phosphatase and inorganic pyrophosphatase in rat bone, kidney and intestine was studied. The rats were injected with TCT every hour for 4 hours. They were divided into groups and were sacrificed 1 h after the first, second, third and fourth injection respectively. The plasma calcium was found to be reduced. Enzyme studies showed that: a) in tibia metaphysis homogenates alkaline phosphatase increased in response to TCT, to 198, 175, 154 and 183 per cent of the non-injected rats after 1, 2, 3, and 4 injections, respectively; inorganic pyrophosphatase was elevated to 356, 209, 221, 425 per cent after the same TCT injections. b) In kidney homogenates alkaline phosphatase was reduced to 75, 53, 79, 68 per cent of the non-injected rats after 1, 2, 3 and four doses, respectively; inorganic pyrophosphatase was reduced to 78, 56, 77 and 71 per cent after the same injections of TCT. c) In the jejunum, alkaline phosphatase was found to be 88.5, 71, 91 and 115 per cent of the untreated rats after 1, 2, 3 and 4 injections, respectively; pyrophosphatase in this tissue was found to be 105, 102, 102 and 113 per cent of the normal under the above conditions. The results indicate: 1. TCT causes increases in alkaline phosphatase and inorganic pyrophosphatase activities in bone. The increase of pyrophosphatase is significantly more marked than the increase of alkaline phosphatase; 2. in kidney tissue, the action of TCT on these two enzymes is slower and their activities are equally reduced; 3. in the jejunum no significant effect of TCT on the activity of these two enzymes was observed.

EVALUASI ANR PADA TRANSMISI DATA NETWORK TERHADAP WP-REST API DALAM APLIKASI ANDROID

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Agung Riyadi
Keyword(s):  
Large Data ◽  
Data Retrieval ◽  
Test Results ◽  
Android Application ◽  
Retrieval Process ◽  
Request Queue ◽  
Plant Data ◽  
Android Development ◽  
Rest Api ◽  
The One

The One of many way to connect to the database through the android application is using volleyball and RESTAPI. By using RestAPI, the android application does not directly connect to the database but there is an intermediary in the form of an API. In android development, Android-volley has the disadvantage of making requests from large and large data, so an evaluation is needed to test the capabilities of the Android volley. This research was conducted to test android-volley to retrieve data through RESTAPI presented in the form of an application to retrieve medicinal plant data. From the test results can be used by volley an error occurs when the back button is pressed, in this case another process is carried out if the previous volley has not been loaded. This error occurred on several android versions such as lollipops and marshmallows also on some brands of devices. So that in using android-volley developer need to check the request queue process that is carried out by the user, if the data retrieval process by volley has not been completed, it is necessary to stop the process to download data using volley so that there is no Android Not Responding (ANR) error.Keywords: Android, Volley, WP REST API, ANR Error

Evaluation of Road Utilisation as Space For Holding Social Ceremonies in Indigenous Residential Area of Ogbomoso, Nigeria

2018 ◽  
Vol 1 (March 2018) ◽  
Author(s):  
S.A Okanlawon ◽  
O.O Odunjo ◽  
S.A Olaniyan
Keyword(s):  
Transport Infrastructure ◽  
Noisy Environment ◽  
Policy Makers ◽  
The Core ◽  
Local Roads ◽  
Strict Enforcement ◽  
The Mean ◽  
The One ◽  
The City ◽  
The Town

This study examined Residents’ evaluation of turning transport infrastructure (road) to spaces for holding social ceremonies in the indigenous residential zone of Ogbomoso, Oyo State, Nigeria. Upon stratifying the city into the three identifiable zones, the core, otherwise known as the indigenous residential zone was isolated for study. Of the twenty (20) political wards in the two local government areas of the town, fifteen (15) wards that were located in the indigenous zone constituted the study area. Respondents were selected along one out of every three (33.3%) of the Trunk — C (local) roads being the one mostly used for the purpose in the study area. The respondents were the residents, commercial motorists, commercial motorcyclists, and celebrants. Six hundred and forty-two (642) copies of questionnaire were administered and harvested on the spot. The Mean Analysis generated from the respondents’ rating of twelve perceived hazards listed in the questionnaire were then used to determine respondents’ most highly rated perceived consequences of the practice. These were noisy environment, Blockage of drainage by waste, and Endangering the life of the sick on the way to hospital; the most highly rated reasons why the practice came into being; and level of acceptability of the practice which was found to be very unacceptable in the study area. Policy makers should therefore focus their attention on strict enforcement of the law prohibiting the practice in order to ensure more cordial relationship among the citizenry, seeing citizens’ unacceptability of the practice in the study area.

Tele-ophthalmology for screening for eye diseases in older patients with cognitive complaints

2020 ◽  
pp. 1357633X1989388
Author(s):  
Anne-Sophie Boureau ◽  
Helene Masse ◽  
Guillaume Chapelet ◽  
Laure de Decker ◽  
Pascal Chevalet ◽  
...  
Keyword(s):  
Cognitive Assessment ◽  
Older Patients ◽  
Screening Method ◽  
Poor Quality ◽  
Eye Diseases ◽  
Ophthalmological Examination ◽  
Cognitive Complaints ◽  
The Mean ◽  
To Come ◽  
Retinal Photographs

Introduction Population-based studies show a significant increase in the prevalence of visual impairment in older patients. However, older patients and patients with lower Mini-Mental State Examination (MMSE) scores have few ophthalmological assessments. The main objective of our study was to evaluate the feasibility of tele-ophthalmological screening for ophthalmological diseases in older patients referred for cognitive assessment. Methods This monocentric prospective study included patients referred to a memory clinic for cognitive assessment. All patients underwent a geriatric assessment comprising a cognitive assessment associated with tele-ophthalmological screening undertaken by an orthoptist, including undilated retinal photography. The retinal photographs were subsequently sent to an ophthalmologist. We identified patients who were not eligible for ophthalmological assessment, for patients that had to come back due to poor-quality retinal photographs and finally for detected eye diseases. The association between the geriatric variable and newly detected eye diseases was analysed in univariable and multivariable analyses. Results The mean age of the 298 patients included was 83.5 years  ± 5.65; 29.5% were male. The mean MMSE score was 20.8 ± 5.2; 66.3% of patients had a diagnosis of dementia. Eighteen patients (6.0%) were not eligible for ophthalmological examination and 13 patients (4.6%) were asked to come back owing to poor-quality retinal photographs. Forty-one patients (13.7%) had a newly detected eye disease. In multivariable analysis, patients with a lower MMSE had significantly more newly identified eye diseases. Discussion The tele-ophthalmological screening method identified unknown ophthalmological diseases requiring specialised management in this older population with cognitive complaints.

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