scholarly journals The MetaboLights repository: curation challenges in metabolomics

Database ◽  
2013 ◽  
Vol 2013 ◽  
Author(s):  
Reza M. Salek ◽  
Kenneth Haug ◽  
Pablo Conesa ◽  
Janna Hastings ◽  
Mark Williams ◽  
...  

Abstract MetaboLights is the first general-purpose open-access curated repository for metabolomic studies, their raw experimental data and associated metadata, maintained by one of the major open-access data providers in molecular biology. Increases in the number of depositions, number of samples per study and the file size of data submitted to MetaboLights present a challenge for the objective of ensuring high-quality and standardized data in the context of diverse metabolomic workflows and data representations. Here, we describe the MetaboLights curation pipeline, its challenges and its practical application in quality control of complex data depositions. Database URL: http://www.ebi.ac.uk/metabolights

2010 ◽  
Vol 108-111 ◽  
pp. 1477-1481
Author(s):  
Xiao Hong Shen ◽  
Gao Shan Wang

With the progress of our society, the consumer needs present a trend of individuation. Hence the manufacturing modes of many products change to individual character manufacturing mode, in which the producer should acquire the customer needs exactly and timely and translate them to high quality products. In this process, quality control plays a key role. This paper develops a quality control system, in which a synthetic process quality judging method against individual manufacturing is adopted. The method makes up the blemish of traditional SPC method and can work well even when it lacks enough data. The practical application of the system has proved its effectiveness and practicability.


2019 ◽  
pp. 25-27
Author(s):  
N. V. Antyufeeva, ◽  
A. V. Slavin ◽  
V. A. Bolshakov

Modern multifunctional thermoanalytical complexes equipped with computers are inherently mobile laboratories. They are able to solve a wide variety of problems in materials science and technology, both in applied research and in the quality control of products supplied to manufacturing enterprises. Using the example of experimental data obtained in the study of the curing processes of thermosetting semi-finished products (prepregs) of polymer composite materials (PCM), the methodological possibilities of modern devices for thermal analysis are shown. They allow investigating and predicting changes in the technological properties of prepregs in a wide temperature range.


2009 ◽  
pp. 23-45 ◽  
Author(s):  
A. Radygin

The article deals with key tendencies in the development of Russia’s market of mergers and acquisitions in the first decade of the 21st century. Quantitative parameters are analyzed by using available in the open access data bases for the years 2003-2008 taking into consideration new tendencies relating to 2008 financial crisis. An active role of the state played in the market of corporate control represents an important factor. Special attention is given to issues of development of Russia’s system of legal norms regulating the market of mergers and acquisitions.


Information ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 65
Author(s):  
Yuta Nemoto ◽  
Vitaly Klyuev

While users benefit greatly from the latest communication technology, with popular platforms such as social networking services including Facebook or search engines such as Google, scientists warn of the effects of a filter bubble at this time. A solution to escape from filtered information is urgently needed. We implement an approach based on the mechanism of a metasearch engine to present less-filtered information to users. We develop a practical application named MosaicSearch to select search results from diversified categories of sources collected from multiple search engines. To determine the power of MosaicSearch, we conduct an evaluation to assess retrieval quality. According to the results, MosaicSearch is more intelligent compared to other general-purpose search engines: it generates a smaller number of links while providing users with almost the same amount of objective information. Our approach contributes to transparent information retrieval. This application helps users play a main role in choosing the information they consume.


Author(s):  
Marta Margeta ◽  
Peter Gould ◽  
Lili-Naz Hazrati ◽  
Veronica Hirsch-Reinshagen ◽  
Werner Paulus

Scholarly communication faces increasing economical and ethical challenges, including pricing policies and overbearing behavior of commercial publishing houses. Based on the hypothesis that a diamond open access neuropathology journal of a high scientific and technical quality can be run entirely by neuropathologists, we launched Free Neuropathology (FNP; freeneuropathology.org) in January 2020. Classical publisher activities, such as copyediting, layout, website maintenance, and journal promotion, are undertaken by neuropathologists and neuroscientists using free open access software. The journal is free for both readers and authors, and papers are published under a Creative Commons BY SA licence, where copyright remains with the authors. Based on 26 articles published by August 2020, it takes FNP 11.1 days from submission to first, and 19.9 days to final, decision. High-quality copyediting, layout, and online publishing in the final format is accomplished in only 8 days. Absence of a commercial publisher enables prioritization of democratic and scientifically-driven decisions on editorial structure, website design, journal promotion, paper formatting, special article series, and number of accepted papers. This new model of journal publishing, which returns the control of scholarly communication to scientists, will be of interest to neuropathologists and wider scientific community alike.Learning ObjectivesSummarize the current state and driving forces behind commercial and non-commercial scientific publishing in neuropathology.Describe the advantages and challenges of a non-commercial publishing platform for neuropathology.


2020 ◽  
Vol 4 (1) ◽  
pp. 29-38
Author(s):  
Heather Brodie Perry

AbstractAccess to information encourages innovation and leads to participation in society of individuals. The emergence of Open Access supports the inclusion of all, including the voices of the traditionally marginalized, yet access alone is insufficient to enable consumers to effectively use information. Power structures can influence the information available and silence opposing viewpoints. Industry disinformation can influence viewpoints and shape policy in ways that can be detrimental to individuals and the community. Information consumers may not possess the competence required to navigate the complex information ecosystem to find the accurate, high-quality, resources required to meet their need. Libraries have a role in assisting consumers develop the critical evaluation capabilities essential to the exercise of informed skepticism when evaluating truth claims. Access is essential; however, without the knowledge to determine the quality and validity of information, a consumer can be misled in ways that can cause harm to themselves and society.


2021 ◽  
Author(s):  
Florian Betz ◽  
Magdalena Lauermann ◽  
Bernd Cyffka

<p>In fluvial geomorphology as well as in freshwater ecology, rivers are commonly seen as nested hierarchical systems functioning over a range of spatial and temporal scales. Thus, for a comprehensive assessment, information on various scales is required. Over the past decade, remote sensing based approaches have become increasingly popular in river science to increase the spatial scale of analysis. However, data-scarce areas have been mostly ignored so far despite the fact that most remaining free flowing – and thus ecologically valuable – rivers worldwide are located in regions characterized by a lack of data sources like LiDAR or even aerial imagery. High resolution satellite data would be able to fill this data gap, but tends to be too costly for large scale applications what limits the ability for comprehensive studies on river systems in such remote areas. This in turn is a limitation for management and conservation of these rivers.</p><p>In this contribution, we suggest an approach for river corridor mapping based on open access data only in order to foster large scale geomorphological mapping of river corridors in data-scarce areas. For this aim, we combine advanced terrain analysis with multispectral remote sensing using the SRTM-1 DEM along with Landsat OLI imagery. We take the Naryn River in Kyrgyzstan as an example to demonstrate the potential of these open access data sets to derive a comprehensive set of parameters for characterizing this river corridor. The methods are adapted to the specific characteristics of medium resolution open access data sets and include an innovative, fuzzy logic based approach for riparian zone delineation, longitudinal profile smoothing based on constrained quantile regression and a delineation of the active channel width as needed for specific stream power computation. In addition, an indicator for river dynamics based on Landsat time series is developed. For each derived river corridor parameter, a rigor validation is performed. The results demonstrate, that our open access approach for geomorphological mapping of river corridors is capable to provide results sufficiently accurate to derive reach averaged information. Thus, it is well suited for large scale river characterization in data-scarce regions where otherwise the river corridors would remain largely unexplored from an up-to-date riverscape perspective. Such a characterization might be an entry point for further, more detailed research in selected study reaches and can deliver the required comprehensive background information for a range of topics in river science.</p>


2015 ◽  
Vol 821-823 ◽  
pp. 528-532 ◽  
Author(s):  
Dirk Lewke ◽  
Karl Otto Dohnke ◽  
Hans Ulrich Zühlke ◽  
Mercedes Cerezuela Barret ◽  
Martin Schellenberger ◽  
...  

One challenge for volume manufacturing of 4H-SiC devices is the state-of-the-art wafer dicing technology – the mechanical blade dicing which suffers from high tool wear and low feed rates. In this paper we discuss Thermal Laser Separation (TLS) as a novel dicing technology for large scale production of SiC devices. We compare the latest TLS experimental data resulting from fully processed 4H-SiC wafers with results obtained by mechanical dicing technology. Especially typical product relevant features like process control monitoring (PCM) structures and backside metallization, quality of diced SiC-devices as well as productivity are considered. It could be shown that with feed rates up to two orders of magnitude higher than state-of-the-art, no tool wear and high quality of diced chips, TLS has a very promising potential to fulfill the demands of volume manufacturing of 4H-SiC devices.


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