PS01.152: BODY TEMPERATURE IN THORACOSCOPIC ESOPHAGECTOMY AND AIR CONDITIONING SYSTEM OF OPERATION ROOM

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 92-93
Author(s):  
Hisashi Usuki ◽  
Takayoshi Kishino ◽  
Masao Fujiwara ◽  
Keiichi Okano ◽  
Yasuyuki Suzuki
Keyword(s):  
Body Temperature ◽  
Air Conditioning ◽  
Conflicts Of Interest ◽  
The Body ◽  
Thoracoscopic Esophagectomy ◽  
Air Conditioning System ◽  
Operation Room ◽  
Starting Point ◽  
Group A ◽  
Group B

Abstract Background It is well known that the perioperative hypothermia often cause the perioperative complications. In this study the hypothermia during the thoracoscopic esophagectomy and the relationship between the hypothermia and the air conditioning system of operation room were evaluated. Methods The subject of this study was 58 patients with esophageal cancer. Fifty of them were male and the others were female and the age was 65.2 + -8.4 years old. Forty three of 58 patients underwent the surgery in the old operation rooms (Group A) and 15 of them underwent it in the operation rooms with new air condirioning system (Group B). The 18 measuring points were picked up for each patient, which were from 10 to 180 minutes after start. The body temperatures were measured every 10 minutes after starting anesthesia. The temperature difference comparing with the starting point of surgery and the frequency of hypothermic state were evaluated. ‘Hypothermic state’ was defined that the temperature reduce more than 0.3 centigrade in comparison with the temperature at the starting point of surgery in this study. Results < 1 > The body temperature reduced early 60 minutes and then rose slowly. It reduce 0.22 + -0.35 centigrade at 60 minutes after starting surgery in comparison with the starting point of surgery. < 2–1 > The temperature of the patients in Group A reduced 0.24 + -0.03 centigrade and 0.32 + -0.09 centigrade at 30 and 60 minutes after starting surgery. But, the temperature of the patients in Group B reduced only 0.05 + -0.01 centigrade at 30 minutes after starting surgery and the temperature recovered at 60 minutes. These differences were statistically significant. < 2–2 > The total measuring points were 774 points in Group A and 270 points in Group B. The hypothermic state was observed 353 measuring points (45.6%) in Group A, and only 8 points (3.0%) in Group B. This difference was statistically significant. Conclusion The new operation rooms, in which the temperature of the air flow for the patients and that for surgeons can be set separately, is useful for keeping the body temperature of the patients adequately. Disclosure All authors have declared no conflicts of interest.

Effects of Diet and Mating on Sickle Cell Disease Murine

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 4914-4914
Author(s):  
Huy Tran ◽  
Yessenia Valverde Guevara ◽  
Ritu Jha ◽  
Thu Duong ◽  
Deniz Ercan-Fang ◽  
...  
Keyword(s):  
Stress Reduction ◽  
Grip Force ◽  
Conflicts Of Interest ◽  
Thermal Hyperalgesia ◽  
Nerve Fibers ◽  
The Body ◽  
Deep Tissue ◽  
Cell Counts ◽  
Group A ◽  
Group B

Abstract Patients experiencing chronic and/or recurrent pain show a correlative decline in health and lifespan. In turn, declining health and sensory effects may contribute to persistent pain and poor response to analgesia. We therefore hypothesized that dietary alterations to improve health and stress reduction by mating may reduce chronic pain in male sickle mice. Methods. We used male HbSS-BERK (sickle) mice, which show hyperalgesia as compared to and HbAA-BERK (control) mice (Kohli et al., Blood 2010). Breeders and pups up to 12 wks of age were fed Sickle Mouse Diet (59M3, TestDiet) and 18% Protein Rodent Diet (2018, Harlan), thereafter, called ‘sickle’ and ‘rodent’ diet. Sickle diet contained 26.4% Protein, 11.1% fat and 27.5% and 26% kcal/g of each, respectively. Rodent diet contained 18.6% protein and 6.2% fat, and 24% and 18% kcal/g of each, respectively. Vitamins were about 2-fold higher in sickle as compared to rodent diet. Sickle mice showing hyperalgesia were recruited and treated as follows: [A] Rodent diet without mating (RD/M-); [B] Sickle diet with mating (SD/M+); [C] Rodent diet with mating (RD/M+); [D] Sickle diet without mating (SD/M-) and [E] mice on SD and mating for 4 weeks, were deprived of SD and mating and fed RD. Control mice which do not show hyperalgesia were fed RD without mating. Sensory testing was performed at baseline (BL) at recruitment and weekly, to evaluate mechanical hyperalgesia with von Frey filaments, thermal hyperalgesia in response to heat/cold and grip force for musculoskeletal/deep tissue hyperalgesia. Following the treatments, release of cytokines from skin biopsies was analyzed by cytokine arrays as described by us earlier (Vincent et al., Blood 2013), and spinal cords were analyzed for nociceptive signaling. Results. We did not observe difference in the body weight of mice between different groups at any time. White blood cell counts and spleen weight were significantly increased in group E following the withdrawal of SD and mating as compared to group C on SD/M+ (p<0.05), but the liver and kidney did not show any difference amongst groups. Groups B and C involving mating with SD/M+ or RD/M+, respectively, showed maximum decrease in mechanical, and thermal hyperalgesia following 3 weeks of treatment as compared to baseline (p<0.05 and 0.0001 for mechanical, p<0.001 and 0.0001 for thermal, respectively for B and C), suggesting that mating decreases sensitivity to noxious stimuli including touch and temperature. In group E (mice were in mating and with SD for 4 wks), withdrawal of sickle diet and mating for 4 weeks, led to a significant increase in thermal hyperalgesia as compared to the start of the withdrawal (p<0.05 for mechanical and heat). Group D (SD/M-) showed a significant decline thermal hyperalgesia one week after starting the sickle diet as compared to BL (p<0.0001 for cold and <0.005 for heat). Thus sickle diet in the absence of mating reduced hyperalgesia, but the reduction with sickle diet only (SD/M-) was significantly less than the reduction caused by mating (RD/M+) or by sickle diet with mating (SD/M+), suggesting that mating is more effective than diet in ameliorating pain. None of the groups demonstrated a decrease in grip force, suggesting that deep tissue pain was not influenced or that the strength of mice was not influenced and the influence is perhaps restricted to the periphery (skin). Cytokine profile of the skin showed a significant decrease in IL6, MIP-1a, RANTES, MCP-1 and GM-CSF in group B, (SD/M+) as compared to group A, (RD/M-), indicating that the diet and mating decrease inflammation in the periphery, thus reducing the activation of peripheral nerve fibers, resulting in reduced hyperalgesia. Consistent with reduced inflammation, spinal cords of group B (SD/M+) showed a significant decrease in nociceptive signaling of phosphorylation of Stat3 pathway as compared to group A (RD/M-). Since, Stat3 is associated with transcription of inflammatory cytokines, it likely reduces the inflammatory response in the spinal cord and inflammatory pain. These data suggest that high protein/high fat diet and mating reduce inflammation and hyperalgesia in sickle mice. Stress appears to be a critical factor in the perception of pain, because mating attenuated hyperalgesia. Thus, improving general health and happiness and stress reduction may reduce pain in SCD. Disclosures No relevant conflicts of interest to declare.

Effect of Sample Storage Conditions on Body Burden Analysis of Organic Contaminants in Unionid Mussels

1992 ◽  
Vol 27 (4) ◽  
pp. 833-844 ◽  
Author(s):  
Micheline Hanna
Keyword(s):  
Organic Contaminants ◽  
Body Burden ◽  
Storage Conditions ◽  
The Body ◽  
Sample Storage ◽  
Pcb Congeners ◽  
Unionid Mussels ◽  
Group A ◽  
The Difference ◽  
Group B

Abstract In order to quantitatively assess the effect of sample storage conditions on the body burden analysis of organic contaminants, a comparative analysis was carried out on the unionid mussel Elliptic complanata. The mussels were divided into two groups, each with distinct storage conditions, while Group A was kept in the freezer at −20°C, Group B was kept in the refrigerator for five days at 5°C. All the compounds present in the control were also present in Group B samples. Analysis of the organic contaminants in each of these two groups showed that for total PCB concentrations, the two treatments were not significantly different; however when compared individually 6 of the 13 PCB congeners showed significant differences. The observed differences were relatively small for individual PCB congeners (7.1 to 15.3%), higher for chlorobenzenes (10.5 to 36.4%), and yet higher for HCE (44.1%); the difference for HCE, although large is nevertheless not significant, even if only marginally so.

scholarly journals Comparative study between fascia lata and temporalis fascia in myringoplasty

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Ayman Ali Abdel Fattah ◽  
Abdel Hay Rashad Elasy ◽  
Ahmed Helmy Hoseini ◽  
Tarek Abdel Rahman Abdel Hafez
Keyword(s):  
Tympanic Membrane ◽  
Good Alternative ◽  
Fascia Lata ◽  
The Body ◽  
Temporalis Fascia ◽  
Fascia Graft ◽  
Fascia Lata Graft ◽  
Group A ◽  
The Mean ◽  
Group B

Abstract Background Repair of a perforated tympanic membrane (myringoplasty) can facilitate normal middle ear function, resist infection, and help re-establish normal hearing. Autogenous graft materials are the most popular graft materials used in myringoplasty because of their easy acceptability by the body. This study is conducted to compare between temporalis fascia graft and fascia lata graft in myringoplasty for patients with tubo-tympanic dry perforation. Results A total of 60 patients with persistent dry tympanic membrane perforation were included in our study during the period from January 2018 to May 2020. Patients underwent myringoplasty with temporalis fascia (30 patients as group A) or fascia lata (30 patients as group B). Patients were scheduled for follow-up visits concerning graft status, ear discharge, and audiograms. The mean postoperative air-bone gap in group A was 17.5 ± 4 after 1 month and 8.6 ± 6.9 after 3 months, while in group B, the mean postoperative air-bone gap was 17.6 ± 4.9 after 1 month and 9.4 ± 7.5 after 3 months. There was 90% success in graft uptake in group A, while there was 80% success in group B. Conclusion Using temporalis fascia is still the best and most trustworthy technique of myringoplasty compared to fascia lata graft. However, fascia lata can be a good alternative to temporalis fascia especially in cases of revision myringoplasty, ears having large perforation, or near-total perforation where the chances of residual perforation are high because of the limited margin of remnant tympanic membrane overlapping the graft.

scholarly journals Effect of Virechana Karma along with Guggulu Kalpanas in the management of Medoroga - A Double Arm Study

2020 ◽  
Vol 5 (05) ◽  
pp. 89-95
Author(s):  
Pooja Abhrange ◽  
S. G. Chavan ◽  
Prashanth A.S.
Keyword(s):  
Metabolic Disease ◽  
Prime Factor ◽  
Natural Process ◽  
The Body ◽  
Inclusion Criteria ◽  
Contributing Factors ◽  
Root Cause ◽  
Individual Person ◽  
Group A ◽  
Group B

Metabolism is the natural process of the body, which is necessary to maintenance of the homeostasis of an individual person. Everybody constitutions are always in the process of metabolism, which is a combination of Anabolism (Construction) and Catabolism (Deterioration). As Agni is prime factor for all the Chayapachayakriya. Medoroga, is one of the Metabolic disease, in which contributing factors are Agni, Ama along with Kaphapradhana Tridosha, Medodhathu. Due to various types of etiological factors, the Agni in the body gets vitiated and Jatharagnimandya occurs. By this Jatharagnimandya, Dhathuparinama will not occur properly. This will lead to Medoroga and further many other Upadravas. To correct these conditions, Ayurveda has many modes of therapies like Samshodhana, Samshamana. By these we can correct the metabolism from the root cause. Here 40 Subjects diagnosed with Medoroga w.s.r. to Hyperlipidemia fulfilling the Inclusion criteria were selected for study and randomly categorized into two groups as Group A and Group B each consisting of 20 subjects. For both groups Amapachana with Chitrakadi Vati, Sadhyosnehapana with Murchita Sarshapa Taila, Sarvanga Abhyanga with Murchita Tila Taila followed by Swedana. And Virechana was administered with Virechana Gulika. Than each group received two different Shamanoushadhi. So, the objective of the study is to establish the efficacy of Virechana along with Dashanga Guggulu and Virechana along with Shadushana Guggulu in the management of Medoroga.

scholarly journals Analisis Postur Kerja Operator dengan Metode Rula di Area Gas Cutting

2017 ◽  
Vol 3 (2) ◽  
pp. 73
Author(s):  
Irwan Pegiardi ◽  
Firdanis Setyaning Handika ◽  
Supriyadi Supriyadi
Keyword(s):  
Upper Limb ◽  
Research Method ◽  
The Body ◽  
Sitting Position ◽  
Upper Limbs ◽  
Work Posture ◽  
Long Time ◽  
Group A ◽  
Group B

The gas cutting area has several jobs that are risky to the operator, such as activities with squatting, bending positions. This study aims to determine the risk of work in the gas cutting area as a basis for improving work posture. The method used is RULA (Rapid Upper Limb Assessment) is a research method for investigating disorders of the upper limbs. By measuring the group A score and group B score. Based on the results of the RULA value in the process of operating the machine with a sitting position with a score 3. clearing the cutting plate with a bent position with a score of 5, and the highest score 6 in the grinding plate cutting. To reduce pain in the neck, torso, and arms, operators should not do work postures that cause pain in the body for a long time.

Plantar Hyperhidrosis: The Efficacy of Iontophoresis with Tap water, Glycopyrronium Bromide and Indomethacin

2021 ◽  
Vol 11 (5) ◽  
Author(s):  
Senthilnathan Prof.Dr.C.V. ◽  
Vaishnavi G. ◽  
Keerthana G. ◽  
NandhaKumar S. ◽  
Kotteeswaran Prof.Dr.
Keyword(s):  
Tap Water ◽  
Psychological Trauma ◽  
Mean Value ◽  
The Body ◽  
Negative Ion ◽  
Unknown Etiology ◽  
Mean Values ◽  
Glycopyrronium Bromide ◽  
Group A ◽  
Group B

Hyperhidrosis is an excessive production of sweat more than the physiological amount necessary to maintain thermal homeostasis. Primary focal hyperhidrosis is a disorder of unknown etiology, causing excessive, bilateral, symmetrical sweating on the soles of the foot is called plantar hyperhidrosis. The condition results not only in physical impairment, but also interferes with professional and social life. Although not life-threatening, it is very uncomfortable and cause embarrassment and psychological trauma. Iontophoresis is a helpful method, which includes the presentation of particles into the body tissue through the skin. The essential principle is to place the ion particles under an electrode with the same charge, i.e. negative ion placed under cathode and positive ion placed under anode. This complete process is also known as “technique of ion transfer” into the body tissues by using electrical current as a driving force. It is a comparative study with pre and post intervention. 30 subjects with plantar hyperhidrosis were selected based on the inclusion criteria. The study duration was for about 4 weeks30 subjects of age group between 15 – 25 years with idiopathic plantar hyperhidrosis of both male and female subjects were included in this study. Subjects with cardiac and respiratory disorders, pregnant or lactating, any cuts, abrasions, eczema or infections on plantar aspect, metal implants like pacemakers, Hypersensitivity to the active substance were excluded. The subjects were divided into 3 group Group A treated with iontophoresis using tap water alone. Group B were treated with iontophoresis using tap water along with 3%-5% of anticholinergic drug, glycopyrronium bromide solution. Group C were treated with iontophoresis using tap water along with 1% of indomethacin (NSAID). The result of this study shows that there were significant changes in outcome measures. On comparing Mean values of Group A, Group B & Group C on Minor test (Starch - Iodine Test) tap Water along with Glycopyrronium Bromide (Group B) shows 1.60 which has the Lower Mean value is effective than Group A and Group C .On comparing Mean values of Group A, Group B & Group C on Visual Analog Scale score tap Water along with Glycopyrronium Bromide (Group B) shows 3.80 which has the Lower Mean value is effective than Group A and Group C. On comparing Mean values of Group A, Group B & Group C on Hyperhidrosis Disease Severity Scale tap Water along with Glycopyrronium Bromide (Group B) shows 1.40 which has the Lower Mean value is effective than Group A and Group C. On comparing all the three groups, Group B shows better result than Group C and Group A in outcome measure. This study concluded that Tap water along with glycopyrronium bromide reduces the excessive sweating and decrease the sweating symptoms in subjects with plantar hyperhidrosis.

Evaluation of effect of efficacy of Koshtha Shuddhi in the Management of Gridrasi (Sciatica)

The Healer ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 48-51
Author(s):  
Sandeepanie Maragalawaththa ◽  
E.R.H.S.S. Ediriweera
Keyword(s):  
Medical Condition ◽  
The Body ◽  
Root Cause ◽  
Lower Back ◽  
Effect Of Therapy ◽  
Chief Complaints ◽  
Group A ◽  
Group B ◽  
Gastro Intestinal Tract ◽  
Inflammatory Effect

Introduction: Sciatica is a medical condition of pain going down the leg through back, outside, or front of the leg from the lower back. It can be co-related with Grdrasi caused by both the aggravated Vata and Kapha two elements out of three basic elements of the body. Diagnostic method of disease is different and management also based on root cause of the disease. Sepalika  (Nyctanthes arbor-tristis.Linn.)(Oleacea) leaves are having anti inflammatory effect and analgesic effect. Aim and Objectives: To Evaluate the efficacy of Koshtha (GIT) (Gastro Intestinal tract) Shuddhi (Purification) in the management of Gridrasi w.s.r. to Sciatica. Material and methods: For this study, 20 patients were resisted and divided into two groups. Registered patients of group A and Group B were given Koshtha Shuddhi with Sepalika leaves decoction along with Sashapadi oil Abhyanga and Sand Potali fomentation and Sepalika leaves decoction along with Sashapadi oil Abhyanga and Sand Potali fomentation respectively for 2 weeks before meal. Patients of group A were given 120ml of Vasagudushi decoction with 5ml Eranada oil twice a day for purpose of Koshtha Shuddhi for 3 days. The effect of therapy was evaluated on the basis of changes of chief complaints and SLR test was taken for assessment parameter. Discussion: The statistically significant relief was showed on the chief complaints of Gridrasi (Sciatica) in the both the groups except Ruk (Pain) in group B. SLR of all the patient of present study were in between 30o- 70o in R/side LL (Lower Limb). SLR was changed of both the groups up to 70o-90o and 100% showed relief except 4 patients in the group B. Conclusion: It can be concluded that the Koshtha Shuddhi is showed comparatively better effect than management of Gridrasi (Sciatica) without carried out Koshtha Shuddhi.

Energy-Based Devices Affect the Aesthetic Outcome of Cervical Thyroidectomy and Parathyroidectomy. A Retrospective Study

2021 ◽  
Vol 39 ◽  
Author(s):  
Antonella Pino ◽  
◽  
Lorenzo Gasco ◽  
Daqi Zhang ◽  
Paolo Carcoforo ◽  
...  
Keyword(s):  
Body Dysmorphic Disorder ◽  
The Body ◽  
University Hospital ◽  
Aesthetic Outcome ◽  
Aesthetic Result ◽  
Scar Assessment ◽  
Number Of Patients ◽  
Group A ◽  
Group B ◽  
The Impact

Introduction: Thyroid and parathyroid diseases are very common. Most of these cases are in women and may be amenable to surgery. The patient’s perception that these are not life-threatening diseases leads them to expect an excellent aesthetic result, since the surgical incision area is clearly visible. Objective: To evaluate different scarring outcomes using three different energy-based devices (Harmonic Focus®, Johnson & Johnson, New Brunswick, NJ; Thunderbeat Open Fine Jaw®, Olympus Medical, Tokyo, Japan; LigaSure Small Jaw®, Medtronic, Dublin, Ireland) and to determine the impact of post-thyroidectomy/parathyroidectomy scars on the patient’s quality of life. Methods: One hundred female patients who underwent thyroidectomy or parathyroidectomy between September 2017 and September 2019 at the Endocrine and Minimally Invasive Surgery Department of Messina University Hospital were recruited. A retrospective analysis assessed the thickness of the cervical scar via ultrasound imaging, and the patient’s degree of satisfaction through the Patient and Observer Scar Assessment Scale (POSAS) and the Body Dysmorphic Disorder Questionnaire (BDDQ). Results: The patients were divided into three groups according to the energy-device used: group A (LigaSure SJ (n=38), group B (Harmonic F, n=32) and group C (Thunderbeat OFJ, n=30). The three groups were homogeneous with respect to number of patients, age and surgical procedures. The best aesthetic result, which correlated with the lowest scar thickness, was observed in group A; these patients were more satisfied than those in the other two groups. Moreover, correlations between scar thickness and quantitative variables (such as age or BMI) were not found in any of the groups. Conclusions: Based on the data collected and our experience, the LigaSure Small Jaw® (Medtronic) seems to offer the best aesthetic outcome in patients who undergo transverse cervicotomy for thyroid and parathyroid diseases. However, further prospective studies involving a greater number of cases are needed.

A Foxtail-Shaped Vermilion Flap to Reconstruct the Medial Tubercle in Asymmetric Bilateral Cleft Lip With Contralateral Lesser Form Defect

2019 ◽  
Vol 56 (8) ◽  
pp. 1052-1057
Author(s):  
Yuta Nakajima ◽  
Shunsuke Yuzuriha ◽  
Fumio Nagai ◽  
Kenya Fujita ◽  
Masahiko Noguchi
Keyword(s):  
Cleft Lip ◽  
Primary Repair ◽  
Tertiary Care ◽  
Senior Author ◽  
The Body ◽  
University Hospital ◽  
Bilateral Cleft Lip ◽  
Group A ◽  
Cleft Lip Repair ◽  
Group B

Objective: There have been few reports addressing asymmetric bilateral cleft lip repair with contralateral lesser form defects. Two studies have described the thin medial tubercle as the most common remaining labial deformity. In this study, we aimed to evaluate the use of a foxtail-shaped vermilion flap to reconstruct the median tubercle in primary repair. Design: A blinded retrospective study of photography and chart review. Setting: Shinshu University Hospital, tertiary care. Private practice. Patients: Forty-nine patients with asymmetric bilateral cleft lip with lesser form defects treated using a primary “unilateral” repair by the senior author (S.Y.) between 2007 and 2017. Interventions: The foxtail-shaped vermilion flap was applied at the time of the primary nasolabial repair. This flap is similar to Noordhoff laterally based triangular vermilion flap but with modifications to the shape and length. The body of the flap is wider than the pedicle to add tissue to the center of the vermilion, and the length is sufficiently elongated to reach the lesser side. Main Outcome Measure: Lip shape was graded on a 4-point scale when patients were 1 year old. Results: Twenty-two patients were treated with the foxtail-shaped vermilion flap (group A) and 27 patients with Noordhoff triangular vermilion flap (group B). Group A had a better lip shape than group B ( P = .006). Conclusions: The foxtail-shaped vermilion flap is useful to reconstruct the median tubercle in asymmetric bilateral cleft lip repair with contralateral lesser form defects.

PS01.063: THE EFFECT OF DISEASE DURATION ON SURGICAL OUTCOMES FOR PATIENTS WITH EROSIVE GERD TREATED BY LAPAROSCOPIC SURGERY

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 67-67
Author(s):  
Kazuto Tsuboi ◽  
Nobuo Omura ◽  
Fumiaki Yano ◽  
Masato Hoshino ◽  
Se-Ryung Yamamoto ◽  
...  
Keyword(s):  
Los Angeles ◽  
Surgical Outcomes ◽  
Disease Duration ◽  
Conflicts Of Interest ◽  
Operation Time ◽  
Acid Reflux ◽  
Los Angeles Classification ◽  
Patients Satisfaction ◽  
Group A ◽  
Group B

Abstract Background Erosive gastro-esophageal reflux disease (e-GERD) is associated with various symptoms caused by reflux of acid and gastric contents from the stomach to the esophagus. In general, it seems that as the duration of the disease is longer, surgical outcomes are inferior because of disease progression. The aim of this study is to evaluate the relationship between the disease duration and surgical outcomes of laparoscopic fundoplication (LF). Methods Two hundred and fifty-one (mean age was 53.4 years, male in 166) patients with e-GERD who underwent LF as an initial operation at our institution were extracted from the database. E-GERD was defined as equal to or more than grade A esophagitis by Los Angeles classification. These patients were divided into three groups by the length of disease duration: less than two years in Group A (n = 104), two to 5 years in Group B (n = 68) and equal to or more than 5 years in Group C (n = 79). We analyzed patients’ background, pre-operative symptoms, surgical outcomes, patients’ satisfaction and post-operative course. Before surgery, a standardized questionnaire was used to assess the degree of frequency and severity of symptoms (heartburn, regurgitation, dysphagia, vomiting and chest pain). Moreover, satisfaction with the operation was evaluated using the standardized questionnaire. Results Age and degree of acid reflux by pH-metry were significantly different among the three groups (P = 0.0054 and 0.0345, respectively). As to the pre-operative symptom score, the severity score of heartburn and the frequency score of regurgitation were significantly lower in Group A (P = 0.0225 and 0.031, respectively). Although operation time was significantly difference among the three groups (P = 0.0423), there were no differences in intraoperative blood loss, occurrence of peri-operative complications, post-operative course and patients’ satisfaction. Conclusion Although the patients who suffered equal to or over two years had more severe heartburn and regurgitation because of prolonged acid reflux, the duration of the disease does not seem to affect the surgical outcomes. Disclosure All authors have declared no conflicts of interest.

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