Plantar Hyperhidrosis: The Efficacy of Iontophoresis with Tap water, Glycopyrronium Bromide and Indomethacin

2021 ◽  
Vol 11 (5) ◽  
Author(s):  
Senthilnathan Prof.Dr.C.V. ◽  
Vaishnavi G. ◽  
Keerthana G. ◽  
NandhaKumar S. ◽  
Kotteeswaran Prof.Dr.
Keyword(s):  
Tap Water ◽  
Psychological Trauma ◽  
Mean Value ◽  
The Body ◽  
Negative Ion ◽  
Unknown Etiology ◽  
Mean Values ◽  
Glycopyrronium Bromide ◽  
Group A ◽  
Group B

Hyperhidrosis is an excessive production of sweat more than the physiological amount necessary to maintain thermal homeostasis. Primary focal hyperhidrosis is a disorder of unknown etiology, causing excessive, bilateral, symmetrical sweating on the soles of the foot is called plantar hyperhidrosis. The condition results not only in physical impairment, but also interferes with professional and social life. Although not life-threatening, it is very uncomfortable and cause embarrassment and psychological trauma. Iontophoresis is a helpful method, which includes the presentation of particles into the body tissue through the skin. The essential principle is to place the ion particles under an electrode with the same charge, i.e. negative ion placed under cathode and positive ion placed under anode. This complete process is also known as “technique of ion transfer” into the body tissues by using electrical current as a driving force. It is a comparative study with pre and post intervention. 30 subjects with plantar hyperhidrosis were selected based on the inclusion criteria. The study duration was for about 4 weeks30 subjects of age group between 15 – 25 years with idiopathic plantar hyperhidrosis of both male and female subjects were included in this study. Subjects with cardiac and respiratory disorders, pregnant or lactating, any cuts, abrasions, eczema or infections on plantar aspect, metal implants like pacemakers, Hypersensitivity to the active substance were excluded. The subjects were divided into 3 group Group A treated with iontophoresis using tap water alone. Group B were treated with iontophoresis using tap water along with 3%-5% of anticholinergic drug, glycopyrronium bromide solution. Group C were treated with iontophoresis using tap water along with 1% of indomethacin (NSAID). The result of this study shows that there were significant changes in outcome measures. On comparing Mean values of Group A, Group B & Group C on Minor test (Starch - Iodine Test) tap Water along with Glycopyrronium Bromide (Group B) shows 1.60 which has the Lower Mean value is effective than Group A and Group C .On comparing Mean values of Group A, Group B & Group C on Visual Analog Scale score tap Water along with Glycopyrronium Bromide (Group B) shows 3.80 which has the Lower Mean value is effective than Group A and Group C. On comparing Mean values of Group A, Group B & Group C on Hyperhidrosis Disease Severity Scale tap Water along with Glycopyrronium Bromide (Group B) shows 1.40 which has the Lower Mean value is effective than Group A and Group C. On comparing all the three groups, Group B shows better result than Group C and Group A in outcome measure. This study concluded that Tap water along with glycopyrronium bromide reduces the excessive sweating and decrease the sweating symptoms in subjects with plantar hyperhidrosis.

scholarly journals Effects of Swiss ball exercise and Pilates exercise on core muscle strengthening in college cricketers

Biomedicine ◽  
2020 ◽  
Vol 40 (3) ◽  
pp. 377-380
Author(s):  
K. Kamatchi ◽  
B. Arun ◽  
G. Tharani ◽  
G. Yuvarani ◽  
G. Vaishnavi ◽  
...  
Keyword(s):  
Mean Value ◽  
Terminal Segment ◽  
Core Stability ◽  
Lower Limbs ◽  
Age Group ◽  
Mean Values ◽  
Muscle Strengthening ◽  
Group A ◽  
Group B ◽  
Swiss Ball

Introduction and Aim: Cricket is one of the most popular game in India played by men and women of all ages. Core stability is defined as the ability to control the position and movement of the trunk over the pelvis to allow optimum production, transfer and control of force and movement to the terminal segment. Major muscles involved are pelvic floor muscles, Transverse abdominis, multifidus, internal and external obliques, and rectus abdominis. Core is used to stabilize the thorax and the pelvis during dynamic movement. The study helps to compare the effectiveness of Swiss ball exercise and Pilates exercise on gaining core muscle strength. The aim of the study is to compare the effect of Swiss ball exercise and Pilates exercise on core muscle strengthening in college cricketers. Materials and Methods: The design of the study is comparative type. The study was carried out in faculty of Physiotherapy, Dr.M.G.R. Educational and Research Institute. The study sample of 30 male college cricketers between the age group of 18 to 25 years are included in the study. Individuals with associated neuromuscular conditions, any injuries to lower limbs and any spinal injuries have been excluded in the study. Swiss ball and Pilates mat are the materials used. Sphygmomanometer is the outcome measure.30 male individuals between the age group of 18 to 25 years were divided into two groups, group A and group B. Individuals in the group A (n=15) received the Swiss ball exercise and group B (n=15) received Pilates exercise for 4 session/ week for 6 weeks. Results: On comparing the mean values of group A and group B on double leg lowering test (DLLT), it shows significant decrease in the post test mean values but (group B- Pilates exercise) shows (30.60) which has the lower mean value is more effective than (group A- Swiss ball exercise) (46.80) at P ? 0.001. Hence, null hypothesis is rejected. Conclusion: The study concluded that both the group was effective but while comparing Pilates exercise showed the potential treatment option than swiss ball exercise. Hence, Pilates exercise was effective on core muscle strengthening in college cricketers. Keywords: Swiss ball; Pilates mat; core muscle; sphygmomanometer.

The Effect of Gongronema Latifolum (Utazi) on Some Haematological Parameters of Rabbit

2020 ◽  
Author(s):  
Obeagu Emmanuel Ifeanyi
Keyword(s):  
Mean Value ◽  
Control Group ◽  
Mean Values ◽  
Platelet Counts ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Differential White Blood Cell ◽  
Group D ◽  
Gongronema Latifolium

The hematological features of Gongronema latifolium, aqueous leaves extract was evaluated using standard methods. After 10 days of consecutive infusions into 9 experimental animals (rabbits). The rabbits were monitored and the following parameters determined; hemoglobin (HB), PCV, Platelet, WBC, Differential White Blood Cell. The Rabbits were grouped into 4, one consisting of control (group A), group B was fed with 0.5 mg/kg, group C with 1.0 mg/kg, and Group D with 1.5mg/kg of the aqueous extract of Gongronemalatifolium. The mean values obtained for hemoglobin estimation for the control group is 5.9 ± 4.1 g/dl, 9.1 ± 2.9 g/dl for group B 10.2 ± 1.8 g/dl for group C and 12.8 ± 0.1 g/dl for group D with no significant increase on the PCV estimation, the mean value for the control (group A) is 17.7 ± 12.3%, 27.3 ± 8.7% for group B, group C (30.6 ± 5.4%) and D (28.4 ± 0.3) show increase that statistically significant (p > 0.01). the platelet counts of group C (600 ± 0 x 109/L) and D(600 ± 0 x 109/L) show significant increase (p > 0.01) when compared with the control (600 ± 00). But the platelet value of group B (550 ± 50 x 109/L) shows no difference. No significant changes were observed in the White Blood Counts of the test groups B (3.5 ± 0.5 x 109/L), C (1.9 + 2.1 x 109/L) and D(3.6 ± 0.4) when compared with the control group (2.9 ± 1.9). The values obtained from the differential White Blood Counts (Neutrophils, Lymphocytes, Eosinophils and Monocytes) were not significant. Therefore, Gongronemalatifolium, when properly taken as a nutritional diet, causes beneficial changes on hemoglobin, packed cell volumes and platelet counts of consumers.

scholarly journals Effect of a plant versus animal based diet on lipid profile of yoga practicing medical students: a pilot study

2018 ◽  
Vol 6 (4) ◽  
pp. 1207
Author(s):  
Sanasam Meetali ◽  
Shashikiran H. C. ◽  
Prashanth Shetty ◽  
Ganesh Prasad ◽  
Chandrakanth K. K.
Keyword(s):  
Lipid Profile ◽  
Serum Triglyceride ◽  
Gastrointestinal Diseases ◽  
Vegetarian Diet ◽  
Mean Value ◽  
Diet Group ◽  
The Body ◽  
Blood Cholesterol ◽  
Group A ◽  
Group B

Background: Foods play an important role in human health. An excess accumulation of cholesterol in the body is one of the main causes of cardio vascular disease, hypertension, type 2 diabetes mellitus, dyslipidemia and mortality. In the interests of food safety and public health, plants and their compounds are now re-emerging as an alternative approach to treat gastrointestinal diseases. The present study was designed to discuss changes in blood cholesterol levels after the consumption of animal based (non vegetarian) and plant based (vegetarian) food on yoga practising medical students.Methods: Of 81 subjects, a total of 60 subjects within the age group 18 to 22 years were selected for the study and were divided into two groups, non-vegetarian diet group (group A; n=30) and vegetarian diet group (group B; n=30). Subjects in the group A were given a non vegetarian diet and group B a vegetarian diet for a period of 10 days. Assessments were done at baseline and after 10 days.Results: There were no statistically significant changes seen in the lipid profiles of group B and group A after the application of a paired t test. In this study the mean value of total cholesterol, serum triglyceride, serum LDL and serum VLDL were found to be slightly higher in vegetarian group than the non-vegetarian group. Mean value of serum HDL was found to be higher in non-vegetarian group than the vegetarian.Conclusions: The present study concludes that there are more changes in the pre and post lipid profile assessments of the vegetarian group in comparison to the non-vegetarian group.

scholarly journals XYLAZINE-KETAMINE ANAESTHESIA; COMPARATIVE STUDIES IN MALE AND FEMALE CANE RATS (THRYONOMYS SWINDERIANUS)

2016 ◽  
Vol 9 (1) ◽  
pp. 52
Author(s):  
Olatunji-akioye A ◽  
Ojiaka H N ◽  
Samuel E. S
Keyword(s):  
Muscle Relaxation ◽  
Mean Value ◽  
Atropine Sulphate ◽  
Male And Female ◽  
Mean Values ◽  
Ketamine Anaesthesia ◽  
Body Weights ◽  
Group A ◽  
The Mean ◽  
Group B

<p><strong>Objective: </strong>Domestication of the Cane rats is on-going globally and might replace the conventional rodents used in biomedical research in future. However, the paucity of information on adequate anaesthesia vis-a-vis xylazine-ketamine drug combination in the male and female Cane rats warranted this study.</p><p><strong>Methods: </strong>Six adult Cane rats {1.8±0.7 kg body weights (bwt.)} assigned into group A (Female) and group B (Male) of three rats each was used for the study. Each animal was premedicated with atropine sulphate (0.05 mg/kg bwt), and later administered xylazine (10 mg/kg bwt) and ketamine (100 mg/kg bwt) intramuscularly. Meanwhile, anaesthetic characteristics and physiologic indices of anaesthesia were monitored.</p><p><strong>Results: </strong>Results obtained showed that the physiologic indices; open eyelids, smooth induction and recovery, skeletal muscle relaxation and somatic analgesia were observed in all the animals, however, the anaesthetic indices; time to induction, time to standing, duration of analgesia and duration of recumbency showed marked sex variations. The mean values for the duration of analgesia and recumbency were significantly elevated (P&lt;0.05) in group B as compared with group A. Similar trend was seen for time to standing, but, it was non-significant (P&gt;005). However, time to induction mean value for group A was non-significantly increased (P&gt;005) when compared with group B. The heart rate, respiratory rate and rectal temperature mean values decreased in both groups non-significantly (P&gt;0.05).<strong></strong></p><p><strong>Conclusion: </strong>Conclusively, the xylazine-ketamine combination produced anaesthesia in Cane rat and the combination is more tolerated in the male Cane rats than the female Cane rats.</p>

scholarly journals Effects of Probiotics Supplementation on Growth Performance and Certain Haemato-biochemical Parameters in Broiler Chickens

1970 ◽  
Vol 2 (1) ◽  
pp. 39-43 ◽  
Author(s):  
MW Islam ◽  
MM Rahman ◽  
SML Kabir ◽  
SM Kamruzzaman ◽  
MN Islam
Keyword(s):  
Biochemical Parameters ◽  
Broiler Chickens ◽  
Live Weight ◽  
The Body ◽  
Mean Values ◽  
Growth Performances ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Key Words Probiotics

The study was carried out to know the effects of probiotics (Protexin® Boost) supplementation on growth performances and haemato-biochemical parameters of "Shaver Star Bro" broiler chickens during the period from September to October 2003. A total of 20, day-old broiler chickens were randomly assigned into four equal groups (n = 5) as A, B, C and D. Group A was considered as control fed with commercial ration while group B, C and D were fed with commercial ration with the addition of 1 g, 2 g and 3 g probiotics / 10 litres drinking water respectively up to 35 days of age. The results showed that the body weight gains corresponding to the different treatments were differed significantly (p < 0.01) at the 1st, 2nd, 3rd, 4th and 5th weeks of age. The meat yield characteristics corresponding to the different treatments did not differ significantly (p > 0.05) whereas bursa weight differed significantly (p < 0.05) among the different groups. The mean values of Hb, PCV and ESR corresponding to the different treatments were significantly (p < 0.01) differ. Triglycerides, HDL, LDL, SGPT and SGOT values corresponding to the different treatments were also differed significantly (p < 0.01). The findings suggest that supplementation of probiotics has significant effects on live weight gain and haemato-biochemical parameters of broiler chickens. Key words: Probiotics; effects; growth; haemato-biochemical parameters; broiler chickens doi: 10.3329/bjvm.v2i1.1933 Bangl. J. Vet. Med. (2004). 2 (1) : 39-43

scholarly journals Diagnosis & Management of Iron Deficiency Anemia via Parental Iron

2012 ◽  
Vol 2 (3) ◽  
pp. 88-90
Author(s):  
MS Iqbal ◽  
MS Ahmed ◽  
TT Ogras ◽  
S Ullah ◽  
JH Asif ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Mean Value ◽  
The Body ◽  
Iron Therapy ◽  
Deficiency Anemia ◽  
Living Things ◽  
Group A ◽  
Group B ◽  
Average Rise

All living things contain liquid inside their bodies which serves many functions like blood act as important connective tissue in transport of oxygen to all the cells similarly to excrete all the waste material from the cell to outside the body. Blood cells contain a red colored pigment which is called hemoglobin and its central portion is iron, when the level of haemoglobin falls in the body this condition is called anemia. To find the actual type of anemia different types of blood tests are conducted a person suffers. Most of the pregnant women suffer with the deficiency of iron. A study of such patients was conducted in Khyber Teaching Hospital Peshawar, and after collection of blood sample their test report indicate that most of the women were suffered with iron deficiency anemia. Total of seventy were taken into 2 groups A (n=40) and B (n=30). For iron deficiency anemia intravenous and intra muscular iron therapy was compared based on Hemoglobin (Hb) level Group A received intra venous iron (2 ampoules/alternate day), while Group B received intra muscular iron (1 ampoules/day). The data was recorded for group A (Hb=8.0±1.1 g/dl) at 15 days interval whereas for group B (Hb=8.8±0.9 g/dl) once prior to delivery. Group A showed an average rise of hemoglobin 2.5 g/dl with mean value of 10.8 g/dl. On the other hand Group B indicated an increase of hemoglobin 1.4 g/dl with mean of 10.2 g/dl target hemoglobin level (11 g/dl) was achieved 87% in group A and only 25% by group B. It was concluded that Intravenous therapy was safe, convenient and more effective than intramuscular iron therapy, in treating iron deficiency anemia. International Journal of Natural Sciences (2012), 2(3):88-90 DOI: http://dx.doi.org/10.3329/ijns.v2i3.12138 

scholarly journals Comparative Evaluation of Efficacy Between Topical Calcipotriol Used Along With Topical Clobetasol And Topical Clobetasol Monotherapy In Treatment Of Alopecia Areata: A Randomised Clinical Trial

2021 ◽  
Author(s):  
MohanLal Gupta ◽  
Shivangna Singh ◽  
Bushra Hasan Khan
Keyword(s):  
Vitamin D ◽  
Alopecia Areata ◽  
The Body ◽  
Mean Values ◽  
Affected Area ◽  
Vitamin D Receptors ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Vitamin D Analogue

Introduction: Alopecia Areata (AA) is a hair disorder characterised by non-scarring, patchy loss of hair from scalp and other parts of the body. For the treatment of AA, topical steroid is one of the first line therapeutic options. Topical vitamin D analogue Calcipotriol has immunomodulatory action. Vitamin D receptors (VDR) are present in the hair follicles,therefore for treatment of AA topical vitamin D analogue Calcipotriol can be considered. Aim: To comparatively evaluate the role in terms of efficacy of topical vitamin D analogue Calcipotriol when used along with topical Clobetasol in comparison to topical Clobetasol used alone for AA treatment. Materials and Methods: In this randomised, open label, clinical study, sixty patients (age 20-32 years) diagnosed with AA were randomly assigned into two groups, thirty patients in each from Sept 2019 to Feb 2020. Topical Clobetasol (0.05%) was applied on the affected area twice a day for 24 weeks by Group A patients. While both topical Clobetasol (0.05%) and topical Calcipotriol (0.005%) was applied on the affected area twice daily for 24 weeks by Group B patients. Parametery like Age, Serum Hydroxy Vitamin D (25(OH)D) and SALT Score were mesured at baseline. At regular intervals of time (i.e baseline, 6,12,24 weeks), SALT (Severity Of Alopecia Tool) score was evaluated. Mean values of the data were evaluated using student's t-test and chi-square test based on whether the data was quantitative or qualitative in nature respectively. p<0.05 was considered statistically significant. Results: With respect to age and gender distribution both the groups were comparable (p>0.05). For patients of group A and group B the mean values of SALT score at baseline were 10.45±5.25 and 9.85±4.95, respectively (p=0.65). In patients of Group A and Group B towards the end of 24 weeks the mean values of SALT score decreased to 5.98±4.32 (p=0.0007) and 3.66±3.53 (p=0.0001), with a greater decrease in SALT score seen in Group B (p=0.05) i.e., the group in which patients were treated with topical calcipotriol 0.005% along with topical Clobetasol 0.05%. Conclusion: Topical calcipotriol 0.005% lotion used along with topical Clobetasol 0.05% lotion had higher efficacy than topical Clobetasol 0.05% lotion used alone, in the treatment of AA.

scholarly journals A prospective study of insulin resistance among infertile women with polycystic ovarian syndrome

2018 ◽  
Vol 7 (9) ◽  
pp. 3786
Author(s):  
M. Smitha ◽  
S. Jyothi ◽  
Anand Acharya
Keyword(s):  
Insulin Resistance ◽  
Mean Value ◽  
The Body ◽  
P Value ◽  
Infertile Women ◽  
Androgen Synthesis ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Infertile Patients

Background: Insulin plays a key role in producing hyperandronism and suppression of insulin secretion in women with PCOS is associated with decreased cytochrome P450c17α. cytochrome P450c17α is a bifunctional enzyme present in ovary is a key enzyme for androgen synthesis. Various studies have been conducted regarding association of insulin resistance with PCOS in infertile patients but there is no study is available about this in our area. So we have designed this study to evaluate insulin resistance in infertile patients with PCOS in rural Andhra Pradesh.Methods: The study population include 180 untreated patients who attended the infertility clinic in outpatient department of obstetrics with infertility due to different cause that include polycystic ovarian disorder also. They have been selected for this study randomly based on inclusion and exclusion criteria.Results: The mean value of glucose insulin ratio was 5.146+2.611 in group A and 8.62 + 5.55 in group B the P value was 0.004909. The mean of LH/FSH ratio was 1.78+0.423 in group A and 1.02 +0.042 in group B. The P value was <0.00001. The mean of HOMA IR was 8.375+ 2.68 in group A and 3.03+ 1.09 in group B, with P value <0.00001. The mean value of QUICKI was 0.2815+ 0.0002875 in group A and 0.347+0.10 in group B with P value <0.00001. Mean serum DHEAS level was 275.59 + 53.48 in infertile patient with PCOS and 208.48 + 36.11 in infertile patients without PCOS. The p value was 0.00012.Conclusions: Based on present study we would like to conclude that the body mass index was high among infertile women with PCOS and a greater number of women presented with acanthosis. There was decrease insulin sensitivity and increase insulin resistance among infertile women with poly cystic ovarian disease, in rural area of Andhra Pradesh and that is not different from the study of other part of world.

scholarly journals Study of the Morphological Characteristics of the Human Gallbladder in Relation to Age and Sex of Bangladeshi People

2014 ◽  
Vol 11 (2) ◽  
pp. 81-85
Author(s):  
Khalilur Rahman ◽  
Afruza Bulbul Akhter ◽  
Selina Anwar ◽  
Anjum Ara Begum ◽  
Sultan Ahmed ◽  
...  
Keyword(s):  
Age Groups ◽  
Morphological Characteristics ◽  
Anatomical Variations ◽  
Mean Value ◽  
Human Gallbladder ◽  
Male And Female ◽  
Mean Values ◽  
Group A ◽  
Group B ◽  
Age And Sex

Context: Variations in the morphology of the gallbladder have long been debated by the abdominal surgeons. So it is important for the surgeons to appreciate the possible anatomical variations that can be encountered during surgery to prevent post operative complications during cholecystectomy. This study was aimed at to find out any variations in the morphology of the postmortem gallbladder in adult Bangladeshi male and female to find out any difference in the gallbladder morphology in relation to age and sex. Material & methods: This study was done on sixty (60) human postmortem gallbladder from Bangladeshi male and females of two age groups- group A age between 20-40 years and group B age between 41-65 years. Among the morphological parameters length, breadth, thickness and volume of the gallbladders were measured. Result: Result of the present study showed that the mean values of gross morphological features of the gall bladder (length, breadth, thickness, volume & weight), were higher in group B than group A except the thickness in female which show somewhat higher mean value in group A than group B. The result showed significantly high value for length and volume in case of male only (p<.05) in group B than group A. When comparison were made between these values in regard of sex, it was found that males of group B showed higher mean value for all parameters than females of group B and result showed a significantly higher value for the length of gallbladder(p<.05). But in case of group A, whereas male had higher mean value for length and weight and, female had higher mean value for breadth, thickness and volume though no values were significantly different. Conclusion: The higher mean values of different parameters of the gallbladder in elderly males and also from their female counterparts of the same age groups may be due to shorter size of the females. Again some parameters showed higher values in females (breadth, thickness and volume) which may indicate the predominance of cholelithiasis in females. Again most of the values in male and female of elderly were higher than the younger groups indicate the formation of gallstones in elderly. DOI: http://dx.doi.org/10.3329/bja.v11i2.20676 Bangladesh Journal of Anatomy, July 2013, Vol. 11 No. 2 pp 81-85

Comparative Study of effectiveness of mobilization with movement (MWM) and End range mobilization (ERM) techniques in frozen shoulder

2018 ◽  
Vol 4 (4) ◽  
pp. 519-522
Author(s):  
Jeyakumar S ◽  
Jagatheesan Alagesan ◽  
T.S. Muthukumar
Keyword(s):  
Range Of Motion ◽  
Frozen Shoulder ◽  
Type I ◽  
Mean Values ◽  
Functional Activities ◽  
Group A ◽  
The Mean ◽  
Group B

Background: Frozen shoulder is disorder of the connective tissue that limits the normal Range of motion of the shoulder in diabetes, frozen shoulder is thought to be caused by changes to the collagen in the shoulder joint as a result of long term Hypoglycemia. Mobilization is a therapeutic movement of the joint. The goal is to restore normal joint motion and rhythm. The use of mobilization with movement for peripheral joints was developed by mulligan. This technique combines a sustained application of manual technique “gliding” force to the joint with concurrent physiologic motion of joint, either actively or passively. This study aims to find out the effects of mobilization with movement and end range mobilization in frozen shoulder in Type I diabetics. Materials and Methods: 30 subjects both male and female, suffering with shoulder pain and clinically diagnosed with frozen shoulder was recruited for the study and divided into two groups with 15 patients each based on convenient sampling method. Group A patients received mobilization with movement and Group B patients received end range mobilization for three weeks. The outcome measurements were SPADI, Functional hand to back scale, abduction range of motion using goniometer and VAS. Results: The mean values of all parameters showed significant differences in group A as compared to group B in terms of decreased pain, increased abduction range and other outcome measures. Conclusion: Based on the results it has been concluded that treating the type 1 diabetic patient with frozen shoulder, mobilization with movement exercise shows better results than end range mobilization in reducing pain and increase functional activities and mobility in frozen shoulder.

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