scholarly journals Successful surgical treatment of a 1160 g neonate with cardiac teratoma and severe foetal hydrops: a case report

2021 ◽  
Author(s):  
Matthias Beichl ◽  
Margarita Thanhaeuser ◽  
Barbara Ulm ◽  
Daniel Zimpfer
Keyword(s):  
Case Report ◽  
Treatment Options ◽  
Histopathological Analysis ◽  
Case Summary ◽  
Staged Approach ◽  
Promising Treatment ◽  
Unfavourable Prognosis ◽  
One Year ◽  
Pericardial Mass ◽  
Clinical Worsening

Abstract Background Prenatally diagnosed pericardial teratoma present a rare finding with an unfavourable prognosis due to frequently associated Foetal hydrops and limited treatment options. We report a successful surgical resection of a prenatally diagnosed cardiac teratoma in a 1160 g neonate with severe Foetal hydrops and cardiac deterioration. Case summary The patient was transferred in utero to our institution due to prior diagnosed pericardial mass and severe foetal hydrops, which necessitated caesarean section one day after arrival at a gestational age of 28 + 0 weeks. After intubation, the patient was stabilized by surgical drainage of 60 mL of pericardial effusion. Further clinical worsening of the patient on the day of life 12 demanded urgent intervention, so that in toto resection of the tumour was performed at a bodyweight of 1160 g. Histopathological analysis revealed a teratoma and the patient is in excellent clinical condition one year after surgery. Discussion This case report demonstrates that an interdisciplinary, two-staged approach can be a feasible and promising treatment option in patients with prenatally diagnosed teratoma and severe Foetal hydrops in a critical circulatory state. Furthermore, it illustrated that resection of pericardial masses can be successfully performed at a bodyweight as low as 1160 g.

scholarly journals Histiocytosis x: Recurrent isolated mandibular lesion (case report)

2003 ◽  
Vol 50 (4) ◽  
pp. 202-204
Author(s):  
Gordana Basta-Jovanovic ◽  
Predrag Stefanovic ◽  
Milena Jovanovic ◽  
Marko Arizanovic
Keyword(s):  
Case Report ◽  
Cystic Lesion ◽  
Iliac Crest ◽  
Histiocytosis X ◽  
Histopathological Analysis ◽  
Laboratory Findings ◽  
Cystic Formation ◽  
Mandibular Body ◽  
Mandibular Defect ◽  
One Year

Histiocytosis X usually affects children and adolescents. In our case, a 54-year-old woman was admitted to hospital for evaluating and treatment of an isolated, painless swelling of the left side of the mandible. Orthopanthomogram showed a cystic formation located on the left side of the mandibular body. Radiographs of the scull and body showed no pathologic changes. Laboratory findings did not reveal any abnormality. Surgical enucleation of the mandibular cystic lesion was performed and histopathological analysis confirmed the presence of histiocytosis X. One year after the first operation a relapse formation was found and surgically removed. Resection of the left side of the mandibular body was performed immediately followed by reconstruction of the mandibular defect with free osseos graft taken from the iliac crest. All follow-ups in the period of three years after the second operation showed no sign of relapse.

scholarly journals Mode of death in Shapiro syndrome: a case report

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Natalia Joanna Braams ◽  
Matthijs L Hendriks ◽  
Vokko P van Halm
Keyword(s):  
Case Report ◽  
Dual Chamber ◽  
Icd Implantation ◽  
Current Case ◽  
Icd Therapy ◽  
Case Summary ◽  
One Year ◽  
Hospital Cardiac Arrest ◽  
Chamber Implantable ◽  
Dual Chamber Implantable

Abstract Background Shapiro syndrome is extremely rare and is characterized by the triad of spontaneous periodic hypothermia, hyperhidrosis and agenesis of the corpus callosum, resulting in neurological and psychological disorders. The exact mechanism of this syndrome is unknown and treatment consists of controlling the periodic attacks. This case report describes a case of Shapiro syndrome presenting with ventricular fibrillation (VF) who was treated with dual chamber implantable cardioverter defibrillator (ICD) therapy. Case summary A 45-year-old man, suffering from Shapiro syndrome with frequent hypothermic attacks, was admitted to the emergency department with an out of hospital cardiac arrest caused by VF due to hypothermia. To prevent cardiac death during future hypothermic attacks with VF, the patient was treated with a dual chamber ICD. Within 1 month after ICD implantation the patient had two events of ventricular tachycardia/VF during hypothermia, which were both successfully terminated by an ICD shock. One year after ICD implantation the patient suffered from an uncontrolled urinary tract infection and the patient passed away. Post-mortem interrogation of the ICD did not reveal further episodes of VF and showed a higher supraventricular heartrate in the last days before his death, probably due to a sinus tachycardia driven by the infection. It was concluded that the most likely cause of death was an uncontrolled sepsis. Discussion The current case showed that ICD therapy can be successful in treating VF episodes in patients with unexpected periods of hypothermia.

scholarly journals Indeterminate Cell Histiocytosis – Case Report and Review of Literature

2018 ◽  
Vol 10 (1) ◽  
pp. 18-24
Author(s):  
Aleksandra R. Vojvodić ◽  
Željko Mijušković ◽  
Lidija Kandolf Sekulović
Keyword(s):  
Dendritic Cells ◽  
Case Report ◽  
Case Reports ◽  
Treatment Options ◽  
Disease Recurrence ◽  
Braf V600e ◽  
Histopathological Analysis ◽  
Entire Body ◽  
S 100 ◽  
Standardized Treatment

Abstract Introduction. Indeterminate cell histiocytosis is a rare proliferative disorder of indeterminate dendritic cells, reported in only 50 case reports so far. It is clinically presented as yellow, red or brown papules and nodules that appear in otherwise healthy adult individuals. Indeterminate cells are distinct dendritic cells of the skin that have ultrastructural similarities to the epidermal Langerhans cells but do not contain the characteristic Birbeck’s granules and they are also langerin-negative, unlike LCH. Indeterminate cell histiocytosis is an exceptional entity with variable clinical, histopathologic or immunohistochemical findings, sharing morphologic and immunophenotypic features with both Langerhans- and non-Langerhans cell histiocytoses. Case Report. We present a case of indeterminate histiocytosis in a 77-year-old man with 3-year history of asymptomatic, multiple reddish and brown papules and nodules over the entire body, including the oral mucosa. Skin biopsy was done, and histopathological analysis with immunohistochemistry was performed. The positive ICH staining of cells for CD68, CD1a, and S-100 enabled us to diagnose ICH in our patient. Also, BRAF V600E mutation was detected in tumor tissue. The treatment was started with methotrexate that was effective for 6 months, but due to the disease recurrence, further therapy with thalidomide was advised, without effect. Conclusion. Indeterminate histiocytosis is a rare disease, therefore no standardized treatment has been established and the treatment options are limited.

Recurrent Cholestasis Due to Ampicillin

2003 ◽  
Vol 37 (3) ◽  
pp. 395-397 ◽  
Author(s):  
Seyfettin Köklü ◽  
Osman Yüksel ◽  
Levent Filik ◽  
Oğuz Üsküdar ◽  
Kadri Altundağ ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Case Report ◽  
Liver Injury ◽  
Literature Review ◽  
Causality Assessment ◽  
Single Case ◽  
Case Summary ◽  
One Year

OBJECTIVE: To present a single case of ampicillin-induced recurrent cholestasis and a literature review. CASE SUMMARY: A 23-year-old man was hospitalized due to recurrent and self-limited cholestatic symptoms. He had used ampicillin before each cholestatic attack. He became well clinically and biochemically each time after cessation of the drug. One year after his recovery and discontinuance of ampicillin, the patient has had no recurrence of cholestasis. An objective causality assessment revealed that the adverse drug reaction was probable. DISCUSSION: Ampicillin-related hepatotoxicity is very rare, with injury being mainly hepatocellular. To our knowledge, there is only 1 case report in the literature referring to chronic cholestatic-type hepatotoxicity related to ampicillin. CONCLUSIONS: Ampicillin, which is one of the most widely used antibiotics, may cause recurrent cholestatic hepatitis. Clinicians should be aware of this adverse effect, and it should be kept in mind during diagnostic workup of liver injury.

scholarly journals Keratoacanthoma associated to cutaneous horn manifestation: case report and difficulty of diagnosis

2015 ◽  
Vol 21 (4) ◽  
pp. 240
Author(s):  
Marina Curra ◽  
Marco Antonio Trevizani Martins ◽  
Laura Campos Hildebrand ◽  
Maria Cristina Munerato ◽  
Manoel Sant'Ana Filho ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Clinical Aspect ◽  
Histopathological Analysis ◽  
Lower Lip ◽  
Cutaneous Horn ◽  
Broad Variety ◽  
One Year ◽  
The One

Background: Cutaneous horn (CH) is a conical hyperkatotic projection of skin with keratotic material. A broad variety of lesions may be found with clinical aspect of cutaneous horn, including malignant tumors.  Case report: We report a case of patient with 77- year-old male, presenting an asymptomatic lesion with clinical aspect of CH in lower lip. The clinical diagnosis hypothesis was squamous cell carcinoma (SCC) and an incisional biopsy was performed. The histopathological analysis revealed a keratoacantoma (KA) and the lesion was completely removed. The one year follow-up revealed no recurrence. Discussion: CH rarely is accompanied by KA. However, KA shows a greater degree of nuclear atypia than SCC making the differentiation of two diseases very difficult. This case highligh the importance of histopathological examination to rule out malignancy.

scholarly journals Fibrous Hamartoma of Infancy in the Scrotum

2019 ◽  
Vol 07 (01) ◽  
pp. e100-e103
Author(s):  
Hrvoje Stepančec ◽  
Zoran Kokot ◽  
Draženko Keretić ◽  
Sandra Radiković ◽  
Donat Grgurović
Keyword(s):  
Case Report ◽  
Clinical Picture ◽  
Benign Tumor ◽  
Male Infant ◽  
Histopathological Analysis ◽  
Rare Tumor ◽  
Diagnostic Challenge ◽  
Fibrous Hamartoma Of Infancy ◽  
One Year

AbstractFibrous hamartoma of infancy is a solid benign tumor of the subcutis, which usually occurs within the first 2 years of life. It predominantly occurs in males, and is clinically presented as a solid, painless, well-limited subcutaneous formation, tending to grow, and in most cases without any symptoms. It occurs in various locations. The aim of this case report was to present a case of a rare tumor of infancy in the scrotal region, in an 8-month-old male infant, with a nonspecific clinical picture, suggestive of a malignant formation, thus presenting a diagnostic challenge for a doctor. The tumor was completely removed. The diagnosis was confirmed by histopathological analysis. One year after the surgical procedure, a follow-up ultrasonography examination showed no relapse.

scholarly journals Sclerotherapy for Oral Pyogenic Granuloma – A case report

2017 ◽  
Vol 13 (2) ◽  
pp. 290-292 ◽  
Author(s):  
Pragya Regmee ◽  
Jyotsna Rimal ◽  
Iccha Kumar Maharjan ◽  
Sushma Pandey ◽  
Deepa Niroula ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Resection ◽  
Treatment Options ◽  
Pyogenic Granuloma ◽  
Vascular Tumor ◽  
Intralesional Injection ◽  
Sodium Tetradecyl Sulfate ◽  
Inflammatory Mass ◽  
Complete Surgical Resection ◽  
One Year

First described by Hullihen in 1844, Pyogenic granuloma (PG) is a benign, exophytic vascular tumor. It is not infective, purulent or granulomatous but a reactive inflammatory mass of blood vessels with few fibroblasts within the mucosa or skin. Without any general agreement, there exist a variety of treatment options (complete surgical resection, cryosurgery, curettage, lasers etc). However, recurrence has been frequently reported.  Sclerotherapy in PG (a vascular tumor) is not as commonly reported as in cases of hemangioma.Herein, we present a case of twenty-eight years old female with a clinical diagnosis of PG, treated with intralesional sodium tetradecyl sulfate (STS). Intralesional injection of 0.2 ml of undiluted STS was given for three visits between 10th of January and 21st of February 2016. The lesion healed completely at the patient’s fourth visit and recurrence was not reported till the patient was followed up for one year, i.e February 2017. 

scholarly journals Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Georgios Koukourakis ◽  
Evagelos Filopoulos ◽  
Kasiani Kapatou ◽  
Georgios Zacharias
Keyword(s):  
Case Report ◽  
Frozen Section ◽  
Treatment Options ◽  
Vascular Tumor ◽  
Needle Aspiration ◽  
Biological Behavior ◽  
Excision Biopsy ◽  
Her Family ◽  
Long Term Follow Up ◽  
One Year

Introduction. Sarcomas of the breast are rare and hemangiopericytoma (HPC) of the breast is even rarer.Case Report. We report a case of a 43-year-old woman who presented with a 4 cm mass in her right breast. Her family history was positive for breast cancer. A fine needle aspiration indicated a malignant vascular tumor. An excision biopsy and frozen section analysis confirmed the presence of an encapsulated mesenchymal tumor. Its morphology and immunohistochemical marker profile were characteristic for a malignant hemangiopericytoma. Thus, she underwent a tumor excision without an axilla sampling. Approximately one year after the surgery the patient is well without local recurrence or metastasis disease to be observed. We also reviewed the literature and discuss the treatment options, characteristics, and immunophenotype of HPC.Conclusions. The accurate diagnosis of HPC depends on the appropriate histological and immunohistochemical examination. Surgical resection is the treatment of choice and due to scarcity of cases and unpredictable biological behavior of these tumors long term follow-up may be warranted.

scholarly journals Efficacy of Lesion Specific Portals in Endoscopic Treatment of Calcaneal Bone Cyst: A Case Report and Literature Review

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 111
Author(s):  
Young Yi ◽  
Jeong Seok Lee ◽  
Jahyung Kim ◽  
So Young Jin ◽  
Sung Hun Won ◽  
...  
Keyword(s):  
Case Report ◽  
Treatment Options ◽  
Bone Cyst ◽  
Standard Technique ◽  
Bone Cysts ◽  
Posterior Aspect ◽  
Minimal Invasiveness ◽  
Main Complaint ◽  
One Year ◽  
Endoscopic Curettage

Background: Calcaneal bone cysts rarely occur and most of them are known to be benign. Among them, simple bone cysts (SBCs) third most commonly occur in the calcaneus and of the many surgical treatment options, endoscopic curettage is recently gaining popularity among surgeons due to its advantages of minimal invasiveness and optimal visualization. As for portal placement for endoscopy, two lateral portals are considered a standard technique, but no rationale has been established for SBCs with abnormal geometry. This case report suggests an SBC with secondary aneurysmal change located outside the Ward’s triangle, as well as an appropriate endoscopic approach. Case Presentation: An 18-year-old male high school student presented with a main complaint of pain at the hind foot level for the past one year, without significant improvement from conservative treatment. An endoscopic curettage through the lesion specific two posterior portals and bone graft using allogeneic cancellous bone were performed. SBC with a secondary aneurysmal bone cyst was diagnosed on pathology. At a one-year follow-up, the patient was painless and had returned to his regular activities. Physical and radiographic examinations revealed that the lesion was completely healed without any evidence of recurrence. Conclusion: For calcaneal bone cysts located at the posterior aspect of the calcaneus, eccentrically medial and abnormally long anterior-posteriorly, we suggest an endoscopic procedure using lesion specific portals such as two posterior portals.

Preventing Premature Weaning: Management Options for Common Lactation Conditions, Including OMT

2020 ◽  
pp. 20-25
Author(s):  
Denise Sackett ◽  
Tala Dajani ◽  
David Shoup ◽  
Uzoma Ikonne
Keyword(s):  
Postpartum Depression ◽  
Family Physician ◽  
Treatment Options ◽  
World Health ◽  
Management Options ◽  
Pharmacological Management ◽  
Control And Prevention ◽  
Lactational Mastitis ◽  
One Year ◽  
Health Organization

The benefits of breastfeeding are well established. The World Health Organization and the Centers for Disease Control and Prevention recommend that mothers breastfeed infants for at least one year, but most children are not breastfed that long because of many factors. Breastfeeding mothers face many challenges to continued breastfeeding, including medical conditions that arise during this period, such as postpartum depression and lactational mastitis. Because of a perceived lack of consistent guidance on medication safety, it can be difficult for the family physician to treat these conditions while encouraging mothers to continue breastfeeding. The purpose of the current review is to summarize and clarify treatment options for the osteopathic family physician treating lactating mothers. We specifically focus on the pharmacological management of contraception, postpartum depression, and lactational mastitis.

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