scholarly journals Disease burden in the Nordic region. Results from the Global Burden of Disease Study 2017 (GBD 2017)

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
A Knudsen ◽  
Keyword(s):  
Risk Factors ◽  
Alcohol Use ◽  
Life Expectancy ◽  
Disease Burden ◽  
Nordic Countries ◽  
Global Burden ◽  
Nordic Region ◽  
Health Differences ◽  
Life Years ◽  
Males And Females

Abstract Background The Nordic countries - Norway, Sweden, Finland, Iceland, Denmark - combine liberal and open-market economies with public welfare and universal health services. As separate countries with differences in culture and lifestyle, important health differences may exist between them. The aim of this study was to compare life expectancy and disease burden by causes and risk factors in the Nordic countries, including Greenland as constituent country under Denmark. Methods Age-standardised overall, cause-, and risk factor-specific estimates of disability-adjusted life-years (DALYs), along with life expectancy, were analysed in the Global Burden of Diseases, Injuries and Risk Factors Study 2017 (GBD 2017). Sex and country specific estimates were compared with Nordic regional estimates. Results Males and females in Denmark (males: 78.8 years, 95% uncertainty interval 78.1-79.5; females: 82.7 years, 81.9-83.4), and males in Finland (78.6 years, 77.8-79.2) had lower life expectancy than the other countries. The lowest life expectancy and highest DALY rates were found among males and females in Greenland. Variation in DALY rates between the countries was primarily due to differences in mortality-related causes, including ischaemic heart disease, chronic obstructive pulmonary disease, lung cancer, alcohol use disorder, and self-harm. These causes dominated male DALYs. There was little country-wise variation in DALYs due to non-fatal diseases, which were dominant causes among females. Smoking and metabolic risk factors were important risk factors across countries, but contributed most to DALYs among males and females in Denmark, and males in Finland (alcohol use only). Conclusions The GBD framework facilitates within-region comparisons for benchmarking exercises and can guide policy development. The comparison of disease burden in the Nordic countries illustrates how differences in risk factors may drive life expectancy and disease burden differences in high-income settings. Key messages Diseases and injuries associated with mortality are important causes of disease burden among males, while non-fatal diseases dominates disease burden among females in the Nordic region. Risk factors differences may drive disease burden differences between the Nordic countries.

scholarly journals Life expectancy and disease burden in the Nordic countries: results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017

2019 ◽  
Vol 4 (12) ◽  
pp. e658-e669 ◽  
Author(s):  
Ann Kristin Knudsen ◽  
Peter Allebeck ◽  
Mette C Tollånes ◽  
Jens Christoffer Skogen ◽  
Kim Moesgaard Iburg ◽  
...  
Keyword(s):  
Risk Factors ◽  
Life Expectancy ◽  
Disease Burden ◽  
Nordic Countries ◽  
Global Burden ◽  
Global Burden Of Diseases ◽  
Burden Of Diseases

scholarly journals Alcohol‐attributed disease burden in four Nordic countries: a comparison using the Global Burden of Disease, Injuries and Risk Factors 2013 study

Addiction ◽  
2016 ◽  
Vol 111 (10) ◽  
pp. 1806-1813 ◽  
Author(s):  
Emilie E. Agardh ◽  
Anna‐Karin Danielsson ◽  
Mats Ramstedt ◽  
Astrid Ledgaard Holm ◽  
Finn Diderichsen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Burden Of Disease ◽  
Disease Burden ◽  
Nordic Countries ◽  
Global Burden Of Disease ◽  
Global Burden

scholarly journals The burden of tuberculosis and attributable risk factors in Brazil, 1990–2017: results from the Global Burden of Disease Study 2017

2020 ◽  
Vol 18 (S1) ◽  
Author(s):  
Francisco Rogerlândio Martins-Melo ◽  
Juliana Maria Trindade Bezerra ◽  
David Soeiro Barbosa ◽  
Mariângela Carneiro ◽  
Kleydson Bonfim Andrade ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alcohol Use ◽  
National Level ◽  
Age Groups ◽  
Absolute Number ◽  
Hiv Positive ◽  
Global Burden ◽  
Years Of Life Lost ◽  
Life Years ◽  
Hiv Negative

Abstract Background Tuberculosis (TB) continues to be an important cause of fatal and non-fatal burden in Brazil. In this study, we present estimates for TB burden in Brazil from 1990 to 2017 using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017). Methods This descriptive study used GBD 2017 findings to report years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs) of TB in Brazil by sex, age group, HIV status, and Brazilian states, from 1990 to 2017. We also present the TB burden attributable to independent risk factors such as smoking, alcohol use, and diabetes. Results are reported in absolute number and age-standardized rates (per 100,000 inhabitants) with 95% uncertainty intervals (UIs). Results In 2017, the number of DALYs due to TB (HIV-negative and HIV-positive combined) in Brazil was 284,323 (95% UI: 240,269–349,265). Among HIV-negative individuals, the number of DALYs was 196,366 (95% UI: 189,645–202,394), while 87,957 DALYs (95% UI: 50,624–146,870) were estimated among HIV-positive individuals. Between 1990 and 2017, the absolute number and age-standardized rates of DALYs due to TB at the national level decreased by 47.0% and 68.5%, respectively. In 2017, the sex–age-specific TB burden was highest among males and in children under-1 year and the age groups 45–59 years. The Brazilian states with the highest age-standardized DALY rates in 2017 were Rio de Janeiro, Pernambuco, and Amazonas. Age-standardized DALY rates decreased for all 27 Brazilian states between 1990 and 2017. Alcohol use accounted for 47.5% of national DALYs due to TB among HIV-negative individuals in 2017, smoking for 17.9%, and diabetes for 7.7%. Conclusions GBD 2017 results show that, despite the remarkable progress in reducing the DALY rates during the period, TB remains as an important and preventable cause of health lost to due premature death and disability in Brazil. The findings reinforce the importance of strengthening TB control strategies in Brazil through integrated and multisectoral actions that enable the access to prevention, early diagnosis, and timely treatment, with emphasis on high-risk groups and populations most vulnerable to the disease in the country.

scholarly journals Cardiovascular diseases burden in Italy, 1990–2017: the Global Burden of Disease Study

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
C Fornari ◽  
P A Cortesi ◽  
F Madotto ◽  
S Conti ◽  
G Crotti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
National Health ◽  
Population Aging ◽  
National Health System ◽  
Total Mortality ◽  
Premature Death ◽  
Global Burden ◽  
High Systolic Blood Pressure ◽  
Life Years

Abstract Background Cardiovascular diseases (CVDs) are still the leading cause of mortality, morbidity and disability in Europe. Consequently, an exhaustive estimation of CVDs burden and cardiovascular risk factors impact is crucial for healthcare planning and resource allocation. In Italy, data on CVDs burden are sparse. This study aims to assess the global Italian CVDs burden and to analyze time changes from 1990 to 2017 within the country and in comparison to other European states. Methods We used data from the 2017 Global Burden of Diseases (GBD) study to estimate CVDs prevalence, mortality and disability-adjusted life-years (DALYs) in Italy from 1990 to 2017. We also analyzed burden attributable to CVDs-related risk factors. Finally, Italian estimations were compared to those of the other 28 European Union countries. Results CVDs were still the first cause of death (34.8% of total mortality) in Italy in 2017. A significant decrease in CVDs burden was observed since 1990: age-standardized prevalence (-12.7%), mortality rate (-53.75%), and DALYs rate (-55.54%) all decreased. Similar patterns were observed also in the majority of European countries. Despite these trends, all-ages CVDs prevalent cases increased from 5.75 million to 7.49 million. More than 80% of CVDs burden could be attributed to known modifiable risk factors such as high systolic blood pressure, dietary risks, high LDL cholesterol, and impaired kidney function. Conclusions Data showed a decline in cardiovascular mortality and DALYs, which reflects the success in terms of reducing disability, premature death and early incidence of CVDs. However, the burden of CVDs is still high, as population aging and the increased prevalent cases require more access to care and generate more years lived with disability, which in turn leads to higher costs for the National Health Service and society. More efficient prevention strategies at community and individual level are needed. Key messages Despite decreasing trends in CVDs mortality and DALYs, the burden of CVDs is still high in Italy. A joined approach of the National Health System stakeholders is needed to keep reducing the CVDs burden.

Examination of incidence, mortality and disability-adjusted life years and risk factors of breast cancer in 49 Asian countries, 1990–2019: estimates from Global Burden of Disease Study 2019

2021 ◽  
Author(s):  
Rajesh Sharma
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Mortality Rate ◽  
Burden Of Disease ◽  
Global Burden ◽  
Disability Adjusted Life Years ◽  
Asian Countries ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Standardized Mortality Rate

Abstract Background This study presents an up-to-date, comprehensive and comparative examination of breast cancer’s temporal patterns in females in Asia in last three decades. Methods The estimates of incidence, mortality, disability-adjusted-life-years and risk factors of breast cancer in females in 49 Asian countries were retrieved from Global Burden of Disease 2019 study. Results In Asia, female breast cancer incidence grew from 245 045[226 259–265 260] in 1990 to 914 878[815 789–1025 502] in 2019 with age-standardized incidence rate rising from 21.2/100 000[19.6–22.9] to 35.9/100 000[32.0–40.2] between 1990 and 2019. The death counts more than doubled from 136 665[126 094–148 380] to 337 822[301 454–375 251]. The age-standardized mortality rate rose marginally between 1990 and 2019 (1990: 12.1[11.0–13.1]; 2019: 13.4[12.0–14.9]). In 2019, age-standardized incidence rate varied from 17.2/100 000[13.95–21.4] in Mongolia to 122.5[92.1–160.7] in Lebanon and the age-standardized mortality rate varied 4-fold from 8.0/100 000 [7.2–8.8] in South Korea to 51.9[39.0–69.8] in Pakistan. High body mass index (5.6%), high fasting plasma glucose (5.6%) and secondhand smoke (3.5%) were the main contributory risk factors to all-age disability-adjusted-life-years due to breast cancer in Asia. Conclusion With growing incidence, escalating dietary and behavioural risk factors and lower survival rates due to late-disease presentation in low- and medium-income countries of Asia, breast cancer has become a significant public health threat. Its rising burden calls for increasing breast cancer awareness, preventive measures, early-stage detection and cost-effective therapeutics in Asia.

scholarly journals The Impact of RSV-Associated Respiratory Disease on Children in Asia

2018 ◽  
Vol 14 (03) ◽  
pp. 079-088
Author(s):  
Maduja Divarathne ◽  
Rukshan Ahamed ◽  
Faseeha Noordeen
Keyword(s):  
Risk Factors ◽  
Developing Countries ◽  
Disease Burden ◽  
Heart Diseases ◽  
Epidemiological Studies ◽  
Morbidity And Mortality ◽  
Life Years ◽  
Rsv Infection ◽  
Tract Infections ◽  
The Impact

AbstractAcute respiratory tract infections (ARTIs) are leading contributors to the global infectious disease burden, which is estimated to be 112,900,000 disability adjusted life years. Viruses contribute to the etiology of ARTIs in a big way compared with other microorganisms. Since the discovery of respiratory syncytial virus (RSV) 61 years ago, the virus has been recognized as a major cause of ARTI and hospitalization in children. The morbidity and mortality attributable to RSV infection appear to be higher in infants < 3 months and in those with known risk factors such as prematurity, chronic lung, and congenital heart diseases. Crowded living conditions, exposure to tobacco smoke, and industrial or other types of air pollution also increase the risk of RSV-associated ARTI. Many epidemiological studies have been conducted in developed countries to understand the seasonal patterns and risk factors associated with RSV infections. Dearth of information on RSV-associated morbidity and mortality in Asian and developing countries indicates the need for regional reviews to evaluate RSV-associated disease burden in these countries. Epidemiological studies including surveillance is the key to track the disease burden including risk factors, seasonality, morbidity, and mortality associated with RSV infection in these countries. These data will contribute to improve the clinical diagnosis and plan preventive strategies in resource-limited developing countries.

scholarly journals The Global, Regional, and National Burden and Trends of Breast Cancer From 1990 to 2019: Results From the Global Burden of Disease Study 2019

2021 ◽  
Vol 11 ◽  
Author(s):  
Shangbo Xu ◽  
Yiyuan Liu ◽  
Taofeng Zhang ◽  
Jiehua Zheng ◽  
Weixun Lin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Fasting Plasma ◽  
Life Years ◽  
High Fasting Plasma Glucose

BackgroundThe burden of breast cancer has been increasing globally. The epidemiology burden and trends need to be updated. This study aimed to update the burden and trends of breast cancer incidences, deaths, and disability-adjusted life-years (DALYs) from 1990 to 2019, using the Global Burden of Disease 2019 study.MethodsThe data of incidences, deaths, DALYs, and age-standardized rates were extracted. Estimated annual percentage changes were used to quantify the trends of age-standardized rates. Besides, the population attributable fractions of the risk factors of breast cancer were also estimated.ResultsGlobally, the incidences of breast cancer increased to 2,002,354 in 2019. High social-development index (SDI) quintiles had the highest incidence cases with a declining trend in age-standardized incidence rate. In 2019, the global deaths and DALYs of breast cancer increased to 700,660 and 20,625,313, respectively. From 1990 to 2019, the age-standardized mortality rates and age-standardized DALY rates declined globally, especially in high and high-middle SDI quintiles. Besides, the trends varied from different regions and countries. The proportion of the patients in the 70+ years age group increased globally. Deaths of breast cancer attributable to high fasting plasma glucose and high body mass index increased globally, and high fasting plasma glucose was the greatest contributor to the global breast cancer deaths.ConclusionThe burden of breast cancer in higher SDI quintiles had gone down while the burden was still on the rise in lower SDI quintiles. It is necessary to appeal to the public to decrease the exposure of the risk factors.

scholarly journals Addictive behaviors: where do we stand, and where are we going?

2017 ◽  
Vol 19 (3) ◽  
pp. 215-215 ◽  
Keyword(s):  
Risk Factors ◽  
Alcohol Use ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Addictive Behaviors ◽  
Brain Disorder ◽  
Treatment Approaches ◽  
Biomedical Treatment ◽  
The Way

Tobacco and alcohol use remain the most prevalent addictive behaviors reported and the leading risk factors for global burden of disease, injury, and death. Considering addiction as a chronically relapsing brain disorder has opened up the way for biomedical treatment approaches.

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