scholarly journals Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a newly emerged pathogen: an overview

2020 ◽  
Vol 78 (6) ◽  
Author(s):  
Jitendra Singh Rathore ◽  
Chaitali Ghosh

ABSTRACT Coronavirus disease 2019 (COVID-19) is a viral pneumonia, responsible for the recent pandemic, and originated from Wuhan, China, in December 2019. The causative agent of the outbreak was identified as coronavirus and designated as severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). Few years back, the severe acute respiratory syndrome coronavirus (SARS- CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) were reported to be highly pathogenic and caused severe infections in humans. In the current situation SARS-CoV-2 has become the third highly pathogenic coronavirus that is responsible for the present outbreak in human population. At the time of this review, there were more than 14 007 791 confirmed COVID-19 patients which associated with over 597 105 deaths in more then 216 countries across the globe (as reported by World Health Organization). In this review we have discussed about SARS-CoV, MERS-CoV and SARC-CoV-2, their reservoirs, role of spike proteins and immunogenicity. We have also covered the diagnosis, therapeutics and vaccine status of SARS-CoV-2.

2020 ◽  
Vol 3 (2) ◽  
pp. 139
Author(s):  
Pina Sodano Omizzolo

In mid-December 2019, several atypical cases of pneumonia were detected in hospitals in Wuhan City – Hubei Province – in Inner China. It turns out that the first patients had already fallen ill in early December or even mid-November. However, only on the last day of the year 2019, Chinese doctors were able to officially identify a new virus in a 41-year-old patient admitted 5 days earlier. The virus belongs to the class of “coronavirus”, the same to which the SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) viruses belong. It is initially baptized 2019-nCov, or “new 2019 coronavirus”. In February, the official name assigned to the virus is Sars-COV-2 and the associated disease is named COVID-19. The outbreak took on considerable proportions in China and then spread to the rest of the world, leading the World Health Organization to declare the infection a “pandemic” on 11 March 2020. The containment strategies applied in the most affected countries have proved to be very different in effectiveness, to the point that the lethality of the virus appears very different from country to country. This difference in impact has led to different legal, economic and social consequences.


2020 ◽  
Vol 66 (7) ◽  
pp. 894-897
Author(s):  
Werther Brunow de Carvalho ◽  
Maria Augusta Bento Cicaroni Gibelli ◽  
Vera Lucia Jornada Krebs ◽  
Carla Regina Tragante ◽  
Maria Beatriz Moliterno Perondi

SUMMARY On 11th March 2020, the World Health Organization (WHO) declared the COVID-19 a pandemic. The Obstetrics and Neonatology disciplines needed to be revised to suit the institutional need to expand intensive care beds to care for confirmed or suspected patients with COVID-19 in the state of São Paulo, following the recommendations of the Institutional Crisis Committee. Three different actions were needed: the structuring of teams and advanced medical post to attend COVID-19-free patients and those with suspect or confirmed COVID-19; elaborating the protocols from the delivery room throughout hospitalization. Some special considerations about breastfeeding and rooming-in were needed. The third action was the drafting of a protocol to admit infants from other hospitals with confirmed COVID-19 as the unit never admitted outpatients before.


Author(s):  
Lara Bittmann

On December 31, 2019, WHO was informed of cases of pneumonia of unknown cause in Wuhan City, China. A novel coronavirus was identified as the cause by Chinese authorities on January 7, 2020 and was provisionally named "2019-nCoV". This new Coronavirus causes a clinical picture which has received now the name COVID-19. The virus has spread subsequently worldwide and was explained on the 11th of March, 2020 by the World Health Organization to the pandemic.


Pathogens ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 32
Author(s):  
Giovanni Di Guardo

With over 80 million cases, and 1,800,000 deaths reported at the end of 2020 by the World Health Organization, the “CoronaVirus Disease-2019” (CoViD-19) pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), should be viewed as a global catastrophe [...]


2021 ◽  
Vol 8 (2) ◽  
pp. 01-03
Author(s):  
Ashish Gujrathi

Coronavirus (COVID-19) was recognized in late December in Hubei province of Wuhan city in China. This highly contagious disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is transmitted from humans to humans. After the first case in Wuhan, the disease rapidly spread to other parts of the globe. On March 11, 2020, the World Health Organization (WHO) made an assessment that COVID-19 can be characterized as a pandemic. Thus, social-distancing became an important measure to stop the spread of this disease. Various countries across the world adopted nationwide lockdowns. This led to a completely new scenario for the world, where every business in each industry faced new challenges and witnessed new opportunities. Similarly, the medical personal protective industry, a vital part of the healthcare sector, also witnessed new growth opportunities.


2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Salman Tahir Shafi

In January 2020, the pathogen was identified and named by the World Health Organization as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2). The consequent SARS-CoV-2-related disease was defined as coronavirus disease 2019 (COVID-19). As data emerged about characteristics of the disease, it was found to be associated with increased risk of acute kidney injury (AKI). We explore the recent literature and reports emerging from the epicenters of the pandemic to help our viewers understand the nature of AKI among these patients. 


1970 ◽  
pp. 14-17
Author(s):  
Randa Abul-Husn

The first case of AIDS was reported in Lebanon in 1988. As of July 1994, 2,402 cases of AIDS, 398 ARC (AIDS Related Complex), and 8,423 HN positive cases were reported in the region of the Middle East. The disease is heavily underreported and under-estimated, according to the National AIDS Control Programme in Lebanon. The NACP was established in 1989 by the World Health Organization and the Lebanese Ministry of Health.


2021 ◽  
Vol 10 (1) ◽  
pp. 36-41
Author(s):  
Seyed Hesamaddin Banihashemi ◽  
Ahmadreza Karimi ◽  
Hasti Nikourazm ◽  
Behnaz Bahmanyar ◽  
Dariush Hooshyar

The severe acute respiratory syndrome coronavirus 2 virus and its associated disease, called coronavirus disease 2019 (COVID-19), first appeared in Wuhan, China in December 2019 and quickly spread around the world. Coronavirus was officially named COVID-19 by the World Health Organization and was recognized as a pandemic due to its rapid spread worldwide. Based on the published data, it is hoped to provide a source for later studies and to help prevent and control the contagious COVID-19 and its characteristics, and considerations that surgeons and medical staff must observe during the epidemic.


2020 ◽  
Vol 25 (32) ◽  
Author(s):  
Erik Alm ◽  
Eeva K Broberg ◽  
Thomas Connor ◽  
Emma B Hodcroft ◽  
Andrey B Komissarov ◽  
...  

We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all sequence data from the World Health Organization European Region available until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation, compare the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2.


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