scholarly journals β-Amyloid Burden Predicts Lower Extremity Performance Decline in Cognitively Unimpaired Older Adults

2016 ◽  
pp. glw183 ◽  
Author(s):  
Qu Tian ◽  
Susan M. Resnick ◽  
Murat Bilgel ◽  
Dean F. Wong ◽  
Luigi Ferrucci ◽  
...  
2020 ◽  
Author(s):  
Ming-Chun Hsueh ◽  
Chien-Yu Lin ◽  
Ting-Fu Lai ◽  
Yi Chien Yu ◽  
Shao-Hsi Chang ◽  
...  

Abstract Background: Evidence regarding the association between daily steps recommendation and older adults’ lower limb strength is lacking; thus, this study investigated whether taking at least 7,000 steps/day is cross-sectionally and prospectively related to lower-extremity performance in older Taiwanese adults. Methods: There were 89 community-dwelling adults aged over 60 years (mean age: 69.5 years) attending both baseline and follow-up surveys. This study used adjusted logistic regression analysis to explore cross-sectional and prospective relationships between their accelerometer-assessed daily steps and lower-extremity performance (five-times-sit-to-stand test). Results: This study found the older adults who took 7,000 steps/day were more likely to have better lower-extremity performance cross-sectionally (odds ratio [OR] = 3.82; 95% confidence interval [CI]: 1.04, 13.95; p = 0.04), as well as to maintain or increase their lower-extremity performance prospectively (OR=3.53; 95% CI: 1.05, 11.84; p = 0.04). Conclusions: Our findings support a minimum recommended level of step-based physical activity for older adults, namely, 7,000 steps/day, as beneficial for maintaining or increasing older adults’ lower-extremity performance.


Nutrients ◽  
2015 ◽  
Vol 7 (9) ◽  
pp. 7126-7142 ◽  
Author(s):  
Karen Charlton ◽  
Marijka Batterham ◽  
Kelly Langford ◽  
Jenna Lateo ◽  
Erin Brock ◽  
...  

2015 ◽  
Vol 95 (12) ◽  
pp. 1628-1637 ◽  
Author(s):  
Anabela G. Silva ◽  
Alexandra Queirós ◽  
Pedro Sa-Couto ◽  
Nelson P. Rocha

Background Measurement of function usually involves the use of both performance-based and self-report instruments. However, the relationship between both types of measures is not yet completely understood, in particular for older adults attending primary care. Objective The main objective of the study was to investigate the association between the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) and the Short Physical Performance Battery (SPPB) for older adults at primary care. A secondary objective was to determine the influence of sociodemographic and health-related variables on this relationship. Design This was a cross-sectional study. Methods A total of 504 participants aged 60 years and older from 18 different primary care centers underwent a one-session assessment including: sociodemographic variables, comorbidities, performance, self-reported disability, pain, depressive symptoms, and physical activity. Performance was assessed using the SPPB, and self-reported disability was assessed using the WHODAS 2.0. Results The correlation between WHODAS 2.0 and SPPB scores was strong (r=.65). Regression analysis showed that the SPPB total score explained 41.7% of the variance in WHODAS 2.0 scores (adjusted R2=41.6%). A second model including the SPPB subtests (balance, gait, and sit-to-stand), depressive symptoms, number of pain sites, pain intensity, and level of physical activity explained 61.7% of the variance in WHODAS 2.0 scores (adjusted R2=60.4%). No model improvement was found when considering the 6 WHODAS 2.0 individual domains. Limitations The cross-sectional nature of the study does not allow inferences on causal relationships. Conclusions This study's findings confirm that self-report and performance-based measures relate to different aspects of functioning. Further study is needed to determine if primary care interventions targeting lower extremity performance and depressive symptoms improve self-reported disability.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ming-Chun Hsueh ◽  
Chien-Yu Lin ◽  
Ting-Fu Lai ◽  
Yi-Chien Yu ◽  
Shao-Hsi Chang ◽  
...  

Abstract Background Evidence regarding the association between daily steps recommendation and older adults’ lower limb strength is lacking; thus, this study investigated whether taking at least 7,000 steps/day is cross-sectionally and prospectively related to lower-extremity performance in older Taiwanese adults. Methods There were 89 community-dwelling adults aged over 60 years (mean age: 69.5 years) attending both baseline and follow-up surveys. This study used adjusted logistic regression analysis to explore cross-sectional and prospective relationships between their accelerometer-assessed daily steps and lower-extremity performance (five-times-sit-to-stand test). Results This study found the older adults who took 7,000 steps/day were more likely to have better lower-extremity performance cross-sectionally (odds ratio [OR] = 3.82; 95 % confidence interval [CI]: 1.04, 13.95; p = 0.04), as well as to maintain or increase their lower-extremity performance prospectively (OR = 3.53; 95 % CI: 1.05, 11.84; p = 0.04). Conclusions Our findings support a minimum recommended level of step-based physical activity for older adults, namely, 7,000 steps/day, as beneficial for maintaining or increasing older adults’ lower-extremity performance.


2020 ◽  
Author(s):  
Ming-Chun Hsueh ◽  
Chien-Yu Lin ◽  
Ting-Fu Lai ◽  
Yi Chien Yu ◽  
Shao-Hsi Chang ◽  
...  

Abstract Background: Evidence regarding the association between daily steps recommendation and older adults’ lower limb strength is lacking; thus, this study investigated whether taking at least 7,000 steps/day is cross-sectionally and prospectively related to lower-extremity performance in older Taiwanese adults. 89 community-dwelling adults aged over 60 years (mean age: 69.5 years) who attended both baseline and follow-up surveys. Methods: This study used adjusted logistic regression analysis to explore cross-sectional and prospective relationships between their accelerometer-assessed daily steps and lower-extremity performance (five-times-sit-to-stand test). Results: This study found the older adults who took 7,000 steps/day were more likely to have better lower-extremity performance cross-sectionally (odds ratio [OR] = 3.82; 95% confidence interval [CI]: 1.04, 13.95; p = 0.04), as well as to maintain or increase their lower-extremity performance prospectively (OR=3.53; 95% CI: 1.05, 11.84; p = 0.04). Conclusions: Our findings support a minimum recommended level of step-based physical activity for older adults, namely, 7,000 steps/day, as beneficial for maintaining or increasing older adults’ lower-extremity performance.


2014 ◽  
Vol 2 ◽  
pp. 205031211454652 ◽  
Author(s):  
Adam P Spira ◽  
Christopher Yager ◽  
Jason Brandt ◽  
Gwenn S Smith ◽  
Yun Zhou ◽  
...  

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