scholarly journals Usefulness of quality indicators for antibiotic use: case study for the Netherlands

2016 ◽  
Author(s):  
Alike W. van der Velden ◽  
Monique Roukens ◽  
Ewoudt van de Garde ◽  
Marco Lourens ◽  
Stephanie Natsch
Keyword(s):  
The Netherlands ◽  
Quality Indicators ◽  
Antibiotic Use ◽  
Use Case

scholarly journals A case study on Staphylococcus aureus bacteraemia: available treatment options, antibiotic R&D and responsible antibiotic-use strategies

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Annelie A Monnier ◽  
Evelina Tacconelli ◽  
Christine Årdal ◽  
Marco Cavaleri ◽  
Inge C Gyssens
Keyword(s):  
Staphylococcus Aureus ◽  
Quality Indicators ◽  
Antibiotic Treatment ◽  
Treatment Guidelines ◽  
Treatment Options ◽  
Antibiotic Use ◽  
Current Status ◽  
Clinical Value ◽  
New Antibiotics

Abstract Objectives This case study addresses: (i) antibiotic treatment options for Staphylococcus aureus bacteraemia (SAB), for both empirical and targeted therapy; (ii) the current status of and priorities for the antibiotic pipeline to ensure access of effective antibiotics for SAB; and (iii) strategies for responsible antibiotic use relevant to the clinical management of SAB. Methods Evidence to address the aims was extracted from the following information sources: (i) EUCAST and CLSI recommendations, summaries of product characteristics (SPCs), antibiotic treatment guidelines and the textbook Kucers’ The Use of Antibiotics; (ii) the www.clinicaltrial.gov database; and (iii) quality indicators for responsible antibiotic use. Results Current monotherapy treatment options for SAB include only three drug classes (β-lactams, glycopeptides and lipopeptides), of which two also cover MRSA bacteraemia (glycopeptides and lipopeptides). The analysis of the antibiotic pipeline and ongoing clinical trials revealed that several new antibiotics with S. aureus (including MRSA) coverage were developed in the past decade (2009–19). However, none belonged to a new antibiotic class or had superior effectiveness and their added clinical value for SAB remains to be proven. Responsible antibiotic use for the treatment of SAB was illustrated using 11 quality indicators. Conclusions Awareness of the problem of a limited antibiotic arsenal, together with incentives (e.g. push incentives), is needed to steer the R&D landscape towards the development of novel and effective antibiotics for treating SAB. In the meantime, responsible antibiotic use guided by quality indicators should preserve the effectiveness of currently available antibiotics for treating SAB.

Spectrum Sensing Architecture and Use Case Study: Distributed Sensing over Rayleigh Fading Channels

2009 ◽  
Vol E92-B (12) ◽  
pp. 3606-3615 ◽  
Author(s):  
Chen SUN ◽  
Yohannes D. ALEMSEGED ◽  
Ha Nguyen TRAN ◽  
Hiroshi HARADA
Keyword(s):  
Fading Channels ◽  
Spectrum Sensing ◽  
Rayleigh Fading ◽  
Distributed Sensing ◽  
Rayleigh Fading Channels ◽  
Use Case

scholarly journals Development of key quality indicators for appropriate antibiotic use in the Republic of Korea: results of a modified Delphi survey

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Bongyoung Kim ◽  
◽  
Myung Jin Lee ◽  
Se Yoon Park ◽  
Song Mi Moon ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Quality Indicators ◽  
Antibiotic Stewardship ◽  
Antibiotic Use ◽  
Republic Of Korea ◽  
Cochrane Library ◽  
Surgical Prophylaxis ◽  
Modified Delphi ◽  
Stewardship Program ◽  
The Republic

Abstract Background An effective antibiotic stewardship program relies on the measurement of appropriate antibiotic use, on which there is a lack of consensus. We aimed to develop a set of key quality indicators (QIs) for nationwide point surveillance in the Republic of Korea. Methods A systematic literature search of PubMed, EMBASE, and Cochrane Library (publications until 20th November 2019) was conducted. Potential key QIs were retrieved from the search and then evaluated by a multidisciplinary expert panel using a RAND-modified Delphi procedure comprising two online surveys and a face-to-face meeting. Results The 23 potential key QIs identified from 21 studies were submitted to 25 multidisciplinary expert panels, and 17 key QIs were retained, with a high level of agreement (13 QIs for inpatients, 7 for outpatients, and 3 for surgical prophylaxis). After adding up the importance score and applicability, six key QIs [6 QIs (Q 1–6) for inpatients and 3 (Q 1, 2, and 5) for outpatients] were selected. (1) Prescribe empirical antibiotic therapy according to guideline, (2) change empirical antibiotics to pathogen-directed therapy, (3) obtain culture samples from suspected infection sites, (4) obtain two blood cultures, (5) adapt antibiotic dosage to renal function, and (6) document antibiotic plan. In surgical prophylaxis, the QIs to prescribe antibiotics according to the guideline and initiate antibiotic therapy 1 h before incision were selected. Conclusions We identified key QIs to measure the appropriateness of antibiotic therapy to identify targets for improvement and to evaluate the effects of antibiotic stewardship intervention.

scholarly journals Social Media in and Around a Temporary Large-Scale Refugee Shelter in the Netherlands

2021 ◽  
Vol 7 (2) ◽  
pp. 205630512110249
Author(s):  
Peer Smets ◽  
Younes Younes ◽  
Marinka Dohmen ◽  
Kees Boersma ◽  
Lenie Brouwer
Keyword(s):  
Social Media ◽  
The Netherlands ◽  
Crisis Communication ◽  
Asylum Seekers ◽  
Large Scale ◽  
State Policies ◽  
Refugee Crisis ◽  
Top Down ◽  
And Migration

During the 2015 refugee crisis in Europe, temporary refugee shelters arose in the Netherlands to shelter the large influx of asylum seekers. The largest shelter was located in the eastern part of the country. This shelter, where tents housed nearly 3,000 asylum seekers, was managed with a firm top-down approach. However, many residents of the shelter—mainly Syrians and Eritreans—developed horizontal relations with the local receiving society, using social media to establish contact and exchange services and goods. This case study shows how various types of crisis communication played a role and how the different worlds came together. Connectivity is discussed in relation to inclusion, based on resilient (non-)humanitarian approaches that link society with social media. Moreover, we argue that the refugee crisis can be better understood by looking through the lens of connectivity, practices, and migration infrastructure instead of focusing only on state policies.

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