Effects of Branched-Chain α-Keto Acids on Plasma Amino Acid Concentrations in Carbon Tetrachloride-Intoxicated Rats

1984 ◽  
Vol 114 (7) ◽  
pp. 1235-1241 ◽  
Author(s):  
Misako Okita ◽  
Akiharu Watanabe ◽  
Nobuyuki Takei ◽  
Hideo Nagashima ◽  
Toshihiko Ubuka
Keyword(s):  
Amino Acid ◽  
Carbon Tetrachloride ◽  
Plasma Amino Acid ◽  
Keto Acids ◽  
Branched Chain ◽  
Amino Acid Concentrations

scholarly journals Comparison of the effects of a high- and normal-casein breakfast on satiety, ‘satiety’ hormones, plasma amino acids and subsequent energy intake

2008 ◽  
Vol 101 (2) ◽  
pp. 295-303 ◽  
Author(s):  
Margriet A. B. Veldhorst ◽  
Arie G. Nieuwenhuizen ◽  
Ananda Hochstenbach-Waelen ◽  
Klaas R. Westerterp ◽  
Marielle P. K. J. Engelen ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Energy Intake ◽  
Plasma Amino Acid ◽  
Plasma Amino Acids ◽  
Casein Protein ◽  
Ad Libitum ◽  
Glucagon Like Peptide 1 ◽  
Branched Chain ◽  
Amino Acid Concentrations

The present study compared the effects of a high- and normal-casein-protein breakfast on satiety, ‘satiety’ hormones, plasma amino acid responses and subsequent energy intake. Twenty-five healthy subjects (BMI 23·9 (sem 0·3) kg/m2; age 22 (sem 1) years) received a subject-specific standardised breakfast (20 % of daily energy requirements): a custard with casein as the single protein source with either 10, 55 and 35 (normal-casein breakfast) or 25, 55 and 20 (high-casein breakfast) % of energy (En%) from protein, carbohydrate and fat respectively in a randomised, single-blind design. Appetite profile (visual analogue scale; VAS), plasma glucose, insulin, glucagon-like peptide 1, ghrelin and amino acid concentrations were determined for 4 h; here the sensitive moment in time for lunch was determined. Subjects came for a second set of experiments and received the same custards for breakfast, and an ad libitum lunch was offered at 180 min after breakfast; energy intake was assessed. There were increased scores of fullness and satiety after the 25 En% casein-custard compared with the 10 En% casein-custard, particularly at 180 min (26 (sem 4) v. 11 (sem 5) mm VAS; P < 0·01) and 240 min (13 (sem 5) v. − 1 (sem 5) mm VAS; P < 0·01). This coincided with prolonged elevated plasma amino acid concentrations; total amino acids and branched-chain amino acids were higher after the 25 En% casein-custard compared with the 10 En% casein-custard at 180 and 240 min (P < 0·001). There was no difference in energy intake (3080 (sem 229) v. 3133 (sem 226) kJ for 25 En% and 10 En% respectively; NS) from the ad libitum lunch. In conclusion, a breakfast with 25 % of energy from casein is rated as being more satiating than a breakfast with 10 % of energy from casein at 3 and 4 h after breakfast, coinciding with prolonged elevated concentrations of plasma amino acids, but does not reduce subsequent energy intake.

Effects of Dietary Excesses of the Branched-Chain Amino Acids on Growth, Food Intake and Plasma Amino Acid Concentrations of Kittens

1988 ◽  
Vol 118 (3) ◽  
pp. 311-320 ◽  
Author(s):  
Diane M. Hargrove ◽  
Quinton R. Rogers ◽  
Christopher C. Calvert ◽  
James G. Morris
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Food Intake ◽  
Branched Chain Amino Acids ◽  
Plasma Amino Acid ◽  
Branched Chain ◽  
Amino Acid Concentrations

scholarly journals Effect of food form on postprandial plasma amino acid concentrations in older adults

2011 ◽  
Vol 106 (2) ◽  
pp. 203-207 ◽  
Author(s):  
Travis B. Conley ◽  
John W. Apolzan ◽  
Heather J. Leidy ◽  
Kathryn A. Greaves ◽  
Eunjung Lim ◽  
...  
Keyword(s):  
Older Adults ◽  
Amino Acid ◽  
Insulin Response ◽  
Area Under The Curve ◽  
Plasma Amino Acid ◽  
Time Interaction ◽  
Effect Of Food ◽  
Branched Chain ◽  
Solid Form ◽  
Amino Acid Concentrations

To assess the effect of food form (FF) on postprandial (PP) plasma amino acid (AA) concentrations, ten older adults (five men and five women, age 72 (sem 2) years, BMI 26·0 (sem 0·9) kg/m2) consumed, on separate days, energy and macronutrient-matched test meal replacement products (MRP) (approximately 25 % of the subject's daily energy need; approximately 54 % carbohydrate, 21 % protein, 25 % fat) in beverage and solid form. Blood samples were taken during fasting and throughout the 4 h PP period; plasma AA concentrations were assessed using HPLC. Consumption of each MRP led to an increase in total AA, branched-chain AA (BCAA), essential AA (EAA), non-essential AA (NEAA) and leucine concentrations (4 h area under the curve, AUC) (time effect; P < 0·05). The beverage MRP resulted in a greater initial (i.e. 30 min) and sustained (4 h AUC) increase in total AA, BCAA, EAA, NEAA and leucine concentrations compared with the solid MRP (each effect of FF; P < 0·05). Although there was no effect of FF on PP insulin response, glucose concentration was greater 1 and 2 h after the solid MRP was consumed (FF × time interaction; P < 0·05). For all PP time points combined, total AA concentration was positively associated with plasma insulin (r 0·25) and glucose (r 0·24) concentrations for the solid MRP but not for the beverage MRP. In conclusion, older adults can achieve higher plasma AA concentrations when a protein-containing MRP is ingested in beverage form. The implications of the higher AA availability on anabolic processes warrant investigation.

Plasma Amino Acid Concentrations during Branched-chain Amino Acid Infusions In Stressed Patients

1982 ◽  
Vol 22 (9) ◽  
pp. 747-752 ◽  
Author(s):  
SUKUMAR P. DESAI ◽  
BRUCE R. BISTRIAN ◽  
LYLE L. MOLDAWER ◽  
MARIJEAN M. MILLER ◽  
GEORGE L. BLACKBURN
Keyword(s):  
Amino Acid ◽  
Plasma Amino Acid ◽  
Branched Chain Amino Acid ◽  
Branched Chain ◽  
Amino Acid Concentrations

scholarly journals Correlation of Plasma Amino Acid and Anthropometric Profiles with Brown Adipose Tissue Density in Humans

2021 ◽  
Vol 10 (11) ◽  
pp. 2339
Author(s):  
Miyuki Kuroiwa ◽  
Sayuri Hamaoka-Fuse ◽  
Masahiro Sugimoto ◽  
Yuko Kurosawa ◽  
Yasuko Aita ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Amino Acid ◽  
Brown Adipose Tissue ◽  
Near Infrared ◽  
Winter Season ◽  
Plasma Amino Acid ◽  
Anthropometric Parameters ◽  
Tissue Density ◽  
Brown Adipose ◽  
Branched Chain

This study examined the relationship between plasma amino acid (AA) concentrations, including branched-chain AAs, and brown adipose tissue density (BAT-d). One hundred and seventy-three subjects (69 men, 104 women) aged 22–68 years were recruited during the winter season. AAs were comprehensively quantified using liquid chromatography-time-of-flight-mass spectrometry. The total hemoglobin concentration in the supraclavicular region ([total-Hb]sup), an indicator of BAT-d, was assessed using near-infrared time-resolved spectroscopy. Anthropometric parameters, including age, percentage of body fat, and visceral fat, were evaluated. Factors associated with higher (≥74 µM) or lower (<74 µM) [total-Hb]sup were investigated by multiple logistic regression models that included AA concentrations alone (model 1) or AA concentrations and anthropometric parameters (model 2) as independent variables. When adjusted for the false discovery rate, [total-Hb]sup was positively correlated with glycine and asparagine levels in men and with the serine level in both men and women and was negatively correlated with the branched-chain AA concentration in men. Models 1 and 2 correlated with higher or lower BAT-d for men (r = 0.73, p = 0.015) and women (r = 0.58, p = 0.079) and for men (r = 0.82, p = 0.0070) and women (r = 0.70, p = 0.020), respectively. A combination of anthropometric parameters and plasma AA concentrations could be a reliable biomarker for higher and lower BAT-d.

Sign in / Sign up

Export Citation Format

Share Document