Anemia and Deficiencies of Folate and Vitamin B-6 Are Common and Vary with Season in Chinese Women of Childbearing Age

Abstract The purpose of this study is to construct boundary representation (BREP) phantom for Chinese women of childbearing age, to estimate the external radiation dose and to analyze radiation protection scheme. The BREP phantom for Chinese women of childbearing age was constructed by image segmentation, 3D reconstruction, non-uniform rational B-spline surface construction and voxelization. The photon-irradiated organ absorbed dose-conversion coefficients (DCCK) of the three female specific organs and the photon effective dose-conversion coefficient (ECCK) were calculated by Monte-Carlo method. The results showed that age, body fat-tissue thickness, direction and area of irradiation, organ location and volume all affected the dose of women specific organs when receiving medical exposure. In the case of ensuring the quality of the diagnosis, radiation protection for female specific organs can be achieved by organ dose modulation techniques and reducing exposure area or volume.

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Serum Folate Shows an Inverse Association with Blood Pressure in a Cohort of Chinese Women of Childbearing Age: A Cross-Sectional Study

PLoS ONE ◽

10.1371/journal.pone.0155801 ◽

2016 ◽

Vol 11 (5) ◽

pp. e0155801 ◽

Cited By ~ 2

Author(s):

Minxue Shen ◽

Hongzhuan Tan ◽

Shujin Zhou ◽

Ravi Retnakaran ◽

Graeme N. Smith ◽

...

Keyword(s):

Blood Pressure ◽

Chinese Women ◽

Cross Sectional Study ◽

Serum Folate ◽

Inverse Association ◽

Women Of Childbearing Age ◽

Sectional Study ◽

Childbearing Age ◽

Cross Sectional

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Trends of central obesity and associations with nutrients intake and daily behaviors among women of childbearing age in China

BMC Women s Health ◽

10.1186/s12905-022-01600-9 ◽

2022 ◽

Vol 22 (1) ◽

Author(s):

Zichong Long ◽

Lili Huang ◽

Jiajun Lyu ◽

Yuanqing Xia ◽

Yiting Chen ◽

...

Keyword(s):

Protein Intake ◽

Central Obesity ◽

Linear Mixed Model ◽

Leisure Time Physical Activity ◽

Chinese Women ◽

Health Concern ◽

Age Group ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Nutrients Intake

Abstract Background Obesity among women of childbearing age has becoming an important public health concern. We aimed to describe the trends of central obesity among Chinese women of childbearing age from 2004 to 2011 and to examine its associations with nutrients intake and daily behaviors. Methods Longitudinal data were derived from the China Health and Nutrition Survey. Participants consisted of 2481 women aged 15–44 years old. WC (Waist circumference) and WHtR (Waist to height ratio) were adopted as indicators of central obesity. Generalized linear mixed model was performed to analyze the associations of nutrients intake and daily behaviors with central obesity. Results From 2004 to 2011, the prevalence of central obesity among Chinese women of childbearing age increased from 21.6 to 30.7% (WC as indice) or from 22.8 to 32.6% (WHtR as indice) (both p < 0.001). Protein intake above the AMDR (Acceptable macronutrient distribution range) (OR = 1.21, 95% CI 1.05–1.39, p < 0.01) and non-participation in LTPA (Leisure time physical activity) (OR = 1.45, 95% CI 1.17–1.80, p < 0.001) were risk factors for high WC, and the latter was also associated with high WHtR (OR = 1.36, 95% CI 1.10–1.67, p < 0.01). For those women who had high WC & high WHtR, the impacts of protein intake and LTPA became stronger, especial LTPA (OR = 1.53, 95% CI 1.21–1.94, p < 0.001). Age-stratified analyses found that non-participation in LTPA was key factor for central obesity in 15–34 age group, while protein intake above the AMDR was pronounced in the 35–44 age group. Conclusions Non-participation in LTPA and protein intake above the AMDR were significant contributors of central obesity, which could be intervention targets to deal with the growing trend of central obesity among women of childbearing age.

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Emerging And Legacy PFAS And Cytokine Homeostasis In Women of Childbearing Age

10.21203/rs.3.rs-1217618/v1 ◽

2022 ◽

Author(s):

Min Nian ◽

Wei Zhou ◽

Yan Feng ◽

Yan Wang ◽

Qian Chen ◽

...

Keyword(s):

Chinese Women ◽

Positive Association ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Meso Scale Discovery ◽

Kernel Machine ◽

Cytokine Levels ◽

Unit Increase ◽

Th17 Cytokines ◽

Polyfluoroalkyl Substances

Abstract The effect of legacy and emerging per- and polyfluoroalkyl substances (PFAS) on cytokine homeostasis in human remains poorly understood. This study aimed to evaluate the associations between legacy and emerging PFAS and cytokine profiles, and identify the main contributors to the disturbance of cytokine homeostasis. We quantified 21 PFAS in 198 Chinese women of childbearing age from 2015 to 2016. 13 cytokines were measured using the Meso Scale Discovery U-PLEX and V-PLEX platforms. The associations between PFAS exposure and cytokine levels were assessed using multiple linear regression (single-exposure), and Bayesian kernel machine regression (BKMR) models (PFAS mixture exposure). In single PFAS models, legacy and alternative PFAS were positively associated with Th1 and Treg cytokines, and negatively associated with Th2 and Th17 cytokines. For instance, each ln-unit increase in 6:2 chlorinated perfluoroalkyl ether sulfonic acid (6:2 Cl-PFESA), perfluorooctanoic acid (PFOA), and perfluorooctane sulfonate (PFOS) was associated with a decrease in IL-10 by -0.228 (95% CI: -0.336, -0.120), -0.153 (95% CI: -0.277, -0.030), and -0.174 (95% CI: -0.339, -0.010), respectively. The BKMR model showed a significantly positive association of PFAS mixture with TGF-β and a negative association with IL-10. Overall, these results indicate that both legacy and emerging PFAS may affect the homeostasis of cytokines.

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Prevalence of Metabolic Syndrome and Overweight/Obesity among Chinese Women of Childbearing Age: A Cross-Sectional Epidemic Study

Journal of Anesthesia & Clinical Research ◽

10.4172/2155-6148.1000444 ◽

2014 ◽

Vol 05 (09) ◽

Author(s):

Xiaomiao Zhao

Keyword(s):

Metabolic Syndrome ◽

Chinese Women ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Cross Sectional

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Plasma folate deficiency increases the risk for abnormal blood pressure in Chinese women of childbearing age

Nutrition Research ◽

10.1016/j.nutres.2021.12.003 ◽

2021 ◽

Author(s):

Yushan Du ◽

Shuangbo Xia ◽

Jinjuan Zhang ◽

Le Zhang ◽

Jufen Liu

Keyword(s):

Blood Pressure ◽

Chinese Women ◽

Folate Deficiency ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Plasma Folate

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Intent to have a second child among Chinese women of childbearing age following China’s new universal two-child policy: a cross-sectional study

BMJ Sexual & Reproductive Health ◽

10.1136/bmjsrh-2018-200197 ◽

2019 ◽

Vol 46 (1) ◽

pp. 59-66

Author(s):

Jue Liu ◽

Min Liu ◽

Shikun Zhang ◽

Qiuyue Ma ◽

Qiaomei Wang

Keyword(s):

Chinese Women ◽

Cross Sectional Study ◽

Central China ◽

Women Of Childbearing Age ◽

Sectional Study ◽

Childbearing Age ◽

Related Factors ◽

Cross Sectional ◽

Second Child ◽

Child Policy

IntroductionChina’s one-child policy was replaced by a new universal two-child policy in 2015; however, few studies have addressed the intent to have a second child and resulting related issues.MethodsWe performed a cross-sectional study on 11 991 Chinese women, 18–49 years of age, from 11 provinces in 2016–2017, in order to assess the intent for a second child among Chinese women of childbearing age and other related factors after the introduction of China’s new universal two-child policy.ResultsWe found that the overall prevalence of the intent to have a second child was 39.4% and that economic, childrearing, and health barriers affected fertility intent. Multivariate logistic regression models showed that the age range of 25–39 years (aOR 1.28–1.30), living in Eastern (aOR 1.28, 95% CI 1.10 to 1.50) or Central China (aOR 1.52, 95% CI 1.27 to 1.78), living in a rural area (aOR 1.62, 95% CI 1.47 to 1.78), being a farmer (aOR 1.43, 95% CI 1.09 to 1.88), having a higher household income (aOR 1.13, 95% CI 1.00 to 1.28), having a history of abortion (aOR 1.18, 95% CI 1.05 to 1.31), and already having one child (aOR 3.65 for girls, aOR 2.70 for boys) were associated with a greater intent to have a second child (all p<0.05). Conversely, economic, health, childrearing, and educational barriers were associated with a lower intent to have a second child (aOR 0.65–0.75).ConclusionFour in ten women of childbearing age demonstrated an intent for a second child. We maintain that fertility-related factors be given full consideration when promoting the two-child policy.

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Folate deficiency is associated with nutritional anaemia in Lebanese women of childbearing age

Public Health Nutrition ◽

10.1017/phn2005921 ◽

2006 ◽

Vol 9 (7) ◽

pp. 921-927 ◽

Cited By ~ 23

Author(s):

Lynn Al Khatib ◽

Omar Obeid ◽

Abla-Mehio Sibai ◽

Malek Batal ◽

Nada Adra ◽

...

Keyword(s):

Iron Deficiency ◽

Folate Deficiency ◽

Folate Intake ◽

Vitamin B ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Cross Sectional ◽

Plasma Folate ◽

Iron Deficient ◽

Health Centres

AbstractObjectiveThe objective of this study was to identify the determinants of anaemia in Lebanese women of childbearing age attending health centres in Lebanon.DesignCross-sectional study carried out between May and December 2003. Anthropometric measurements as well as sociodemographic, health and dietary intake data were collected using a questionnaire. Haemoglobin (Hb), plasma ferritin, plasma folate and vitamin B12were assessed using standard laboratory methods.SettingGovernmental health centres in Lebanon.SubjectsFour hundred and seventy non-pregnant Lebanese women aged 15–45 years.ResultsAnaemia (Hb <12 g dl−1) and iron deficiency (ferritin <15 μg l−1) were prevalent in 16.0 and 27.2% of the study sample, respectively. Of the total sample, 7.7% had iron-deficiency anaemia. The percentage of women with either Hb or ferritin deficiency or both was 35.6%. Plasma folate and vitamin B12deficiency was reported in 25.1 and 39.4%, respectively, and 12.6% of the women had both folate and vitamin B12deficiencies. Of the anaemic group, 48.0% of the women had iron deficiency. The intake of iron was lower in iron-deficient than in non-deficient women and a positive relationship was shown between folate intake and its corresponding serum levels. Regression analysis showed that ferritin, plasma folate and family history of anaemia were significant determinants of the anaemia in the sample of women.ConclusionsAnaemia not related to iron deficiency was partly explained by plasma folate deficiency. Measures to control folate and iron deficiency should be considered.

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