scholarly journals Trends of central obesity and associations with nutrients intake and daily behaviors among women of childbearing age in China

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Zichong Long ◽  
Lili Huang ◽  
Jiajun Lyu ◽  
Yuanqing Xia ◽  
Yiting Chen ◽  
...  

Abstract Background Obesity among women of childbearing age has becoming an important public health concern. We aimed to describe the trends of central obesity among Chinese women of childbearing age from 2004 to 2011 and to examine its associations with nutrients intake and daily behaviors. Methods Longitudinal data were derived from the China Health and Nutrition Survey. Participants consisted of 2481 women aged 15–44 years old. WC (Waist circumference) and WHtR (Waist to height ratio) were adopted as indicators of central obesity. Generalized linear mixed model was performed to analyze the associations of nutrients intake and daily behaviors with central obesity. Results From 2004 to 2011, the prevalence of central obesity among Chinese women of childbearing age increased from 21.6 to 30.7% (WC as indice) or from 22.8 to 32.6% (WHtR as indice) (both p < 0.001). Protein intake above the AMDR (Acceptable macronutrient distribution range) (OR = 1.21, 95% CI 1.05–1.39, p < 0.01) and non-participation in LTPA (Leisure time physical activity) (OR = 1.45, 95% CI 1.17–1.80, p < 0.001) were risk factors for high WC, and the latter was also associated with high WHtR (OR = 1.36, 95% CI 1.10–1.67, p < 0.01). For those women who had high WC & high WHtR, the impacts of protein intake and LTPA became stronger, especial LTPA (OR = 1.53, 95% CI 1.21–1.94, p < 0.001). Age-stratified analyses found that non-participation in LTPA was key factor for central obesity in 15–34 age group, while protein intake above the AMDR was pronounced in the 35–44 age group. Conclusions Non-participation in LTPA and protein intake above the AMDR were significant contributors of central obesity, which could be intervention targets to deal with the growing trend of central obesity among women of childbearing age.

2013 ◽  
Vol 22 (4) ◽  
pp. 355-361 ◽  
Author(s):  
C. Barbui ◽  
V. Conti ◽  
M. Purgato ◽  
A. Cipriani ◽  
I. Fortino ◽  
...  

Aims.To determine the prevalence of women of childbearing age with schizophrenia and bipolar disorder exposed to antipsychotic (AP) drugs and mood stabilizers (MS) in Lombardy, a European region of 10 million inhabitants and 1 752 285 women of childbearing age.Methods.The data concerning psychiatric care, drug treatments and pregnancy outcomes were retrieved from local administrative databases during a 12-month census period.Results.During a 12-month census period, 2893 women of childbearing age with schizophrenia (74.8% of all women of childbearing age with schizophrenia) and 918 with bipolar disorder (80.1% of all women of childbearing age with bipolar disorder) were exposed to AP drugs or MS, yielding a prevalence of exposure for women with schizophrenia of 1.65 (95% confidence interval (CI) 1.59–1.71) per 1000 female inhabitants, and for women with bipolar disorder of 0.52 (95% CI 0.49–0.55) per 1000 female inhabitants. Persistent exposure to potentially teratogenic medications accounted for one in every 1000 women of childbearing age. Of the 57 pregnancies in women with schizophrenia, normal delivery was recorded in 23 (40%) cases; of the 26 pregnancies in women with bipolar disorder, normal delivery was recorded in 10 (38%) cases.Conclusions.In women of childbearing age with severe mental disorders, exposure to psychotropic drugs is substantial, which suggests that the issue of reproductive health is epidemiologically relevant and a major public health concern.


2000 ◽  
Vol 130 (11) ◽  
pp. 2703-2710 ◽  
Author(s):  
Alayne G. Ronnenberg ◽  
Marlene B. Goldman ◽  
Iain W. Aitken ◽  
Xiping Xu

2020 ◽  
Vol 189 (4) ◽  
pp. 407-419
Author(s):  
Haowei Zhang ◽  
Si Sun ◽  
Heqing Lu ◽  
Ying Liu

Abstract The purpose of this study is to construct boundary representation (BREP) phantom for Chinese women of childbearing age, to estimate the external radiation dose and to analyze radiation protection scheme. The BREP phantom for Chinese women of childbearing age was constructed by image segmentation, 3D reconstruction, non-uniform rational B-spline surface construction and voxelization. The photon-irradiated organ absorbed dose-conversion coefficients (DCCK) of the three female specific organs and the photon effective dose-conversion coefficient (ECCK) were calculated by Monte-Carlo method. The results showed that age, body fat-tissue thickness, direction and area of irradiation, organ location and volume all affected the dose of women specific organs when receiving medical exposure. In the case of ensuring the quality of the diagnosis, radiation protection for female specific organs can be achieved by organ dose modulation techniques and reducing exposure area or volume.


PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0155801 ◽  
Author(s):  
Minxue Shen ◽  
Hongzhuan Tan ◽  
Shujin Zhou ◽  
Ravi Retnakaran ◽  
Graeme N. Smith ◽  
...  

2019 ◽  
Author(s):  
Mazyanga Lucy Mazaba ◽  
Seter Siziya ◽  
Mwaka Monze ◽  
Daniel Cohen

Abstract Background: Rubella is highly under reported in Zambia as in most sub-Saharan countries despite being a disease of major public health concern especially among women of childbearing age. In September 2016, Zambia introduced a combined measles-rubella vaccine in children 0-14 years. In this study, we estimated the proportion positive for acute rubella among suspected but negative measles cases between 2005 and 2016 and determined its correlates for monitoring rubella epidemiology post-rubella vaccine introduction. Methods: In a retrospective study, 4497 measles IgM negative serum samples from 5686 clinically suspected measles cases were examined for rubella IgM antibodies using the Siemens, Enzygnost® ELISA kit at the national measles laboratory. Data on demographics, year and month of onset were extracted from the surveillance data. Multivariate logistic regression analysis using backward variable selection was conducted to determine independent predictors for acute rubella. The magnitude of association was estimated using adjusted odds ratio with a 95% confidence interval. Results: Overall, a proportion of 29.2% (1313/4497) affecting mostly those between 5 and 24 years was determined. Only age, province, month and year were independently associated with acute rubella. The regional proportions varied from 21.8 – 37.3% peaking in the month of October. Persons in the age group 10-14 years (Adjusted Odds Ratio [AOR]=2.43; 95% CI [2.01 - 2.95]) were more likely while those aged <1 year less likely (AOR=0.31; 95% CI [021 - 0.48]) to have acute rubella compared to those aged 25 years or older. Persons in 2010 were less likely (AOR=0.12; CI [0.05, 0.28]) to have acute rubella compared to those in 2016. While acute rubella was more likely to occur between July and November compared to December, it was less likely to occur between February and May. Conclusions: Rubella virus was circulating in Zambia between 2005 and 2016 affecting mostly persons in the age group 5-24 years peaking in the hot dry season month of October. Although vaccination against rubella has been launched, these baseline data are important to provide a reference point when determining the impact of the vaccination program implemented. Keywords: Rubella, Acute, Proportion, Correlates, Zambia, Pre vaccination era, Immunisation


2022 ◽  
Author(s):  
Min Nian ◽  
Wei Zhou ◽  
Yan Feng ◽  
Yan Wang ◽  
Qian Chen ◽  
...  

Abstract The effect of legacy and emerging per- and polyfluoroalkyl substances (PFAS) on cytokine homeostasis in human remains poorly understood. This study aimed to evaluate the associations between legacy and emerging PFAS and cytokine profiles, and identify the main contributors to the disturbance of cytokine homeostasis. We quantified 21 PFAS in 198 Chinese women of childbearing age from 2015 to 2016. 13 cytokines were measured using the Meso Scale Discovery U-PLEX and V-PLEX platforms. The associations between PFAS exposure and cytokine levels were assessed using multiple linear regression (single-exposure), and Bayesian kernel machine regression (BKMR) models (PFAS mixture exposure). In single PFAS models, legacy and alternative PFAS were positively associated with Th1 and Treg cytokines, and negatively associated with Th2 and Th17 cytokines. For instance, each ln-unit increase in 6:2 chlorinated perfluoroalkyl ether sulfonic acid (6:2 Cl-PFESA), perfluorooctanoic acid (PFOA), and perfluorooctane sulfonate (PFOS) was associated with a decrease in IL-10 by -0.228 (95% CI: -0.336, -0.120), -0.153 (95% CI: -0.277, -0.030), and -0.174 (95% CI: -0.339, -0.010), respectively. The BKMR model showed a significantly positive association of PFAS mixture with TGF-β and a negative association with IL-10. Overall, these results indicate that both legacy and emerging PFAS may affect the homeostasis of cytokines.


2019 ◽  
Vol 46 (1) ◽  
pp. 59-66
Author(s):  
Jue Liu ◽  
Min Liu ◽  
Shikun Zhang ◽  
Qiuyue Ma ◽  
Qiaomei Wang

IntroductionChina’s one-child policy was replaced by a new universal two-child policy in 2015; however, few studies have addressed the intent to have a second child and resulting related issues.MethodsWe performed a cross-sectional study on 11 991 Chinese women, 18–49 years of age, from 11 provinces in 2016–2017, in order to assess the intent for a second child among Chinese women of childbearing age and other related factors after the introduction of China’s new universal two-child policy.ResultsWe found that the overall prevalence of the intent to have a second child was 39.4% and that economic, childrearing, and health barriers affected fertility intent. Multivariate logistic regression models showed that the age range of 25–39 years (aOR 1.28–1.30), living in Eastern (aOR 1.28, 95% CI 1.10 to 1.50) or Central China (aOR 1.52, 95% CI 1.27 to 1.78), living in a rural area (aOR 1.62, 95% CI 1.47 to 1.78), being a farmer (aOR 1.43, 95% CI 1.09 to 1.88), having a higher household income (aOR 1.13, 95% CI 1.00 to 1.28), having a history of abortion (aOR 1.18, 95% CI 1.05 to 1.31), and already having one child (aOR 3.65 for girls, aOR 2.70 for boys) were associated with a greater intent to have a second child (all p<0.05). Conversely, economic, health, childrearing, and educational barriers were associated with a lower intent to have a second child (aOR 0.65–0.75).ConclusionFour in ten women of childbearing age demonstrated an intent for a second child. We maintain that fertility-related factors be given full consideration when promoting the two-child policy.


2011 ◽  
Vol 22 (2) ◽  
pp. 109-122 ◽  
Author(s):  
MUCHABAYIWA F GIDIRI ◽  
IAN A GREER

Obesity is a growing problem in obstetric practice. A recent study from Glasgow (UK) showed that 50% of women of childbearing age are either overweight (Body Mass Index [BMI] = 24.9–29.9kg/m2) or obese with 18% starting pregnancy as obese. Obesity prevalence has doubled over a decade from the early 1990’s. In the US it is estimated that 30% of reproductive-age women have a BMI greater than 30 kg/m while 7% have a BMI > 40 kg/m2. A recent report from the UK found that 5% of women had a BMI >35 kg/m2, 2% > 40 kg/m2 and 0.2% >50 kg/m2 with an association not only with social deprivation, but also with a higher prevalence of pre-existing medical disorders such as diabetes and hypertension and medical complications of pregnancy such as preeclampsia. Obesity was also associated with increased rates of macrosomia, operative delivery and postpartum haemorrhage. These data highlight the fact that obesity is an increasing health concern particularly in young women of childbearing age. Obesity will expose them to significant pregnancy complications ranging from miscarriage and fetal abnormality through to operative delivery and thromboembolism. There are also challenges for the delivery of maternity care to meet the needs of these women. As obesity is associated with significant pregnancy complications it is important that women enter pregnancy with an optimum body weight. Many complications, such as fetal abnormality occur in the first trimester and so pre-pregnancy weight reduction is preferred. Further, there is insufficient evidence to recommend specific dietary and/or physical activity interventions to reduce weight or moderate weight gain during pregnancy.


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