Plasma folate deficiency increases the risk for abnormal blood pressure in Chinese women of childbearing age

AbstractObjectiveThe objective of this study was to identify the determinants of anaemia in Lebanese women of childbearing age attending health centres in Lebanon.DesignCross-sectional study carried out between May and December 2003. Anthropometric measurements as well as sociodemographic, health and dietary intake data were collected using a questionnaire. Haemoglobin (Hb), plasma ferritin, plasma folate and vitamin B12were assessed using standard laboratory methods.SettingGovernmental health centres in Lebanon.SubjectsFour hundred and seventy non-pregnant Lebanese women aged 15–45 years.ResultsAnaemia (Hb <12 g dl−1) and iron deficiency (ferritin <15 μg l−1) were prevalent in 16.0 and 27.2% of the study sample, respectively. Of the total sample, 7.7% had iron-deficiency anaemia. The percentage of women with either Hb or ferritin deficiency or both was 35.6%. Plasma folate and vitamin B12deficiency was reported in 25.1 and 39.4%, respectively, and 12.6% of the women had both folate and vitamin B12deficiencies. Of the anaemic group, 48.0% of the women had iron deficiency. The intake of iron was lower in iron-deficient than in non-deficient women and a positive relationship was shown between folate intake and its corresponding serum levels. Regression analysis showed that ferritin, plasma folate and family history of anaemia were significant determinants of the anaemia in the sample of women.ConclusionsAnaemia not related to iron deficiency was partly explained by plasma folate deficiency. Measures to control folate and iron deficiency should be considered.

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Plasma folate status and dietary folate intake among Chinese women of childbearing age

Maternal and Child Nutrition ◽

10.1111/j.1740-8709.2008.00172.x ◽

2009 ◽

Vol 5 (2) ◽

pp. 104-116 ◽

Cited By ~ 16

Author(s):

Yaling Zhao ◽

Ling Hao ◽

Le Zhang ◽

Yihua Tian ◽

Yiwu Cao ◽

...

Keyword(s):

Chinese Women ◽

Folate Intake ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Dietary Folate ◽

Folate Status ◽

Plasma Folate ◽

Dietary Folate Intake

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Arterial Blood Pressure in Sudanese Women of Childbearing Age

International Journal of Gynecology & Obstetrics ◽

10.1002/j.1879-3479.1980.tb00284.x ◽

1980 ◽

Vol 18 (3) ◽

pp. 212-213

Author(s):

Abdel Salam Gerais ◽

Suad Hassabu

Keyword(s):

Blood Pressure ◽

Arterial Blood Pressure ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Arterial Blood

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Anemia and Deficiencies of Folate and Vitamin B-6 Are Common and Vary with Season in Chinese Women of Childbearing Age

Journal of Nutrition ◽

10.1093/jn/130.11.2703 ◽

2000 ◽

Vol 130 (11) ◽

pp. 2703-2710 ◽

Cited By ~ 60

Author(s):

Alayne G. Ronnenberg ◽

Marlene B. Goldman ◽

Iain W. Aitken ◽

Xiping Xu

Keyword(s):

Chinese Women ◽

Vitamin B ◽

Women Of Childbearing Age ◽

Childbearing Age

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CONSTRUCTION AND APPLICATION OF BREP PHANTOM FOR CHINESE WOMEN OF CHILDBEARING AGE IN RADIATION PROTECTION

Radiation Protection Dosimetry ◽

10.1093/rpd/ncaa056 ◽

2020 ◽

Vol 189 (4) ◽

pp. 407-419

Author(s):

Haowei Zhang ◽

Si Sun ◽

Heqing Lu ◽

Ying Liu

Keyword(s):

Radiation Protection ◽

Chinese Women ◽

Absorbed Dose ◽

Organ Dose ◽

Boundary Representation ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Protection Scheme ◽

Dose Modulation ◽

Female Specific

Abstract The purpose of this study is to construct boundary representation (BREP) phantom for Chinese women of childbearing age, to estimate the external radiation dose and to analyze radiation protection scheme. The BREP phantom for Chinese women of childbearing age was constructed by image segmentation, 3D reconstruction, non-uniform rational B-spline surface construction and voxelization. The photon-irradiated organ absorbed dose-conversion coefficients (DCCK) of the three female specific organs and the photon effective dose-conversion coefficient (ECCK) were calculated by Monte-Carlo method. The results showed that age, body fat-tissue thickness, direction and area of irradiation, organ location and volume all affected the dose of women specific organs when receiving medical exposure. In the case of ensuring the quality of the diagnosis, radiation protection for female specific organs can be achieved by organ dose modulation techniques and reducing exposure area or volume.

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Peranan Ultraviolet B Sinar Matahari terhadap Status Vitamin D dan Tekanan Darah pada Wanita Usia Subur

Kesmas National Public Health Journal ◽

10.21109/kesmas.v0i0.377 ◽

2014 ◽

pp. 256 ◽

Cited By ~ 1

Author(s):

Betty Yosephin ◽

Ali Khomsan ◽

Dodik Briawan ◽

Rimbawan Rimbawan

Keyword(s):

Blood Pressure ◽

Vitamin D ◽

Serum Vitamin ◽

Sun Exposure ◽

Ultraviolet B ◽

P Value ◽

Vitamin D Status ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Anthropometric Parameter

Sinar ultraviolet B adalah sumber utama vitamin D, tetapi wanita usia subur yang bekerja di dalam ruangan mempunyai vitamin D yang rendah meskipun Indonesia negara tropis. Tujuan penelitian ini untuk mengevaluasi peranan paparan sinar matahari pada wanita usia subur terhadap status vitamin D dan tekanan darah. Desain penelitian yang digunakan adalah eksperimen tanpa kelompok kontrol pada 21 wanita sehat. Penelitian ini membandingkan status vitamin D dan tekanan darah sebelum dan setelah mendapat paparan sinar matahari pada wajah dan lengan tiga kali seminggu selama 12 minggu. Analisis data menggunakan uji t-berpasangan. Paparan sinar matahari dapat meningkatkan vitamin D. Serum 25(OH)D meningkat 15,9% dari 15.7 ng/dL menjadi 18,2 ng/dL. Paparan sinar matahari menurunkan tekanan darah sistolik (nilai p = 0,004) dan diastolik (nilai p = 0,011). Ultraviolet B dari sinar matahari 30 menit tiga kali seminggu selama 12 minggu dapat memperbaiki status vitamin D dan tekanan darah.Ultraviolet B sunlight exposure is a primary source of vitamin D, but women of childbearing age who worked in room every day had low serum vitamin D despite Indonesia is a tropical country. The objective of this study was to evaluate the role of sun exposure in women of childbearing age on vitamin D status, and blood pressure. An intervention before-after study without group control was conducted on 21 healthy women. This study compared vitamin D status, and blood pressure before and after receiving ultraviolet B (UVB) from sun exposure on the face and both arms three times a week for 12 weeks. Anthropometric parameter and blood pressure were measured, were determined at baseline and after 12 weeks of sun exposure. The effect of sun exposure can improve vitamin D. Serum 25 (OH)D increase 15.9% from 15.7 ng/dL to 18.2 ng/dL. Sun exposure significantly reduced systolic blood pressure (p value = 0.004), and diastolic blood pressure (p value = 0.011). Ultraviolet B from sun exposure for 30 minutes, 3 times a week for 12 weeks improves the vitamin D status, and blood pressure.

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Trends of central obesity and associations with nutrients intake and daily behaviors among women of childbearing age in China

BMC Women s Health ◽

10.1186/s12905-022-01600-9 ◽

2022 ◽

Vol 22 (1) ◽

Author(s):

Zichong Long ◽

Lili Huang ◽

Jiajun Lyu ◽

Yuanqing Xia ◽

Yiting Chen ◽

...

Keyword(s):

Protein Intake ◽

Central Obesity ◽

Linear Mixed Model ◽

Leisure Time Physical Activity ◽

Chinese Women ◽

Health Concern ◽

Age Group ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Nutrients Intake

Abstract Background Obesity among women of childbearing age has becoming an important public health concern. We aimed to describe the trends of central obesity among Chinese women of childbearing age from 2004 to 2011 and to examine its associations with nutrients intake and daily behaviors. Methods Longitudinal data were derived from the China Health and Nutrition Survey. Participants consisted of 2481 women aged 15–44 years old. WC (Waist circumference) and WHtR (Waist to height ratio) were adopted as indicators of central obesity. Generalized linear mixed model was performed to analyze the associations of nutrients intake and daily behaviors with central obesity. Results From 2004 to 2011, the prevalence of central obesity among Chinese women of childbearing age increased from 21.6 to 30.7% (WC as indice) or from 22.8 to 32.6% (WHtR as indice) (both p < 0.001). Protein intake above the AMDR (Acceptable macronutrient distribution range) (OR = 1.21, 95% CI 1.05–1.39, p < 0.01) and non-participation in LTPA (Leisure time physical activity) (OR = 1.45, 95% CI 1.17–1.80, p < 0.001) were risk factors for high WC, and the latter was also associated with high WHtR (OR = 1.36, 95% CI 1.10–1.67, p < 0.01). For those women who had high WC & high WHtR, the impacts of protein intake and LTPA became stronger, especial LTPA (OR = 1.53, 95% CI 1.21–1.94, p < 0.001). Age-stratified analyses found that non-participation in LTPA was key factor for central obesity in 15–34 age group, while protein intake above the AMDR was pronounced in the 35–44 age group. Conclusions Non-participation in LTPA and protein intake above the AMDR were significant contributors of central obesity, which could be intervention targets to deal with the growing trend of central obesity among women of childbearing age.

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Emerging And Legacy PFAS And Cytokine Homeostasis In Women of Childbearing Age

10.21203/rs.3.rs-1217618/v1 ◽

2022 ◽

Author(s):

Min Nian ◽

Wei Zhou ◽

Yan Feng ◽

Yan Wang ◽

Qian Chen ◽

...

Keyword(s):

Chinese Women ◽

Positive Association ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Meso Scale Discovery ◽

Kernel Machine ◽

Cytokine Levels ◽

Unit Increase ◽

Th17 Cytokines ◽

Polyfluoroalkyl Substances

Abstract The effect of legacy and emerging per- and polyfluoroalkyl substances (PFAS) on cytokine homeostasis in human remains poorly understood. This study aimed to evaluate the associations between legacy and emerging PFAS and cytokine profiles, and identify the main contributors to the disturbance of cytokine homeostasis. We quantified 21 PFAS in 198 Chinese women of childbearing age from 2015 to 2016. 13 cytokines were measured using the Meso Scale Discovery U-PLEX and V-PLEX platforms. The associations between PFAS exposure and cytokine levels were assessed using multiple linear regression (single-exposure), and Bayesian kernel machine regression (BKMR) models (PFAS mixture exposure). In single PFAS models, legacy and alternative PFAS were positively associated with Th1 and Treg cytokines, and negatively associated with Th2 and Th17 cytokines. For instance, each ln-unit increase in 6:2 chlorinated perfluoroalkyl ether sulfonic acid (6:2 Cl-PFESA), perfluorooctanoic acid (PFOA), and perfluorooctane sulfonate (PFOS) was associated with a decrease in IL-10 by -0.228 (95% CI: -0.336, -0.120), -0.153 (95% CI: -0.277, -0.030), and -0.174 (95% CI: -0.339, -0.010), respectively. The BKMR model showed a significantly positive association of PFAS mixture with TGF-β and a negative association with IL-10. Overall, these results indicate that both legacy and emerging PFAS may affect the homeostasis of cytokines.

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Mercury Exposure in Munduruku Indigenous Communities from Brazilian Amazon: Methodological Background and an Overview of the Principal Results

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18179222 ◽

2021 ◽

Vol 18 (17) ◽

pp. 9222

Author(s):

Paulo Cesar Basta ◽

Paulo Victor de Sousa Viana ◽

Ana Claudia Santiago de Vasconcellos ◽

André Reynaldo Santos Périssé ◽

Cristina Barroso Hofer ◽

...

Keyword(s):

Blood Pressure ◽

High Blood Pressure ◽

Indigenous Communities ◽

Brazilian Amazon ◽

Mercury Exposure ◽

Mercury Determination ◽

Women Of Childbearing Age ◽

Childbearing Age ◽

Hair Samples ◽

Exposure Levels

The Amazonian indigenous peoples depend on natural resources to live, but human activities’ growing impacts threaten their health and livelihoods. Our objectives were to present the principal results of an integrated and multidisciplinary analysis of the health parameters and assess the mercury (Hg) exposure levels in indigenous populations in the Brazilian Amazon. We carried out a cross-sectional study based on a census of three Munduruku indigenous villages (Sawré Muybu, Poxo Muybu, and Sawré Aboy), located in the Sawré Muybu Indigenous Land, between 29 October and 9 November 2019. The investigation included: (i) sociodemographic characterization of the participants; (ii) health assessment; (iii) genetic polymorphism analysis; (iv) hair mercury determination; and (v) fish mercury determination. We used the logistic regression model with conditional Prevalence Ratio (PR), with the respective 95% confidence intervals (CI95%) to explore factors associated with mercury exposure levels ≥6.0 µg/g. A total of 200 participants were interviewed. Mercury levels (197 hair samples) ranged from 1.4 to 23.9 μg/g, with significant differences between the villages (Kruskal–Wallis test: 19.9; p-value < 0.001). On average, the general prevalence of Hg exposure ≥ 6.0 µg/g was 57.9%. For participants ≥12 years old, the Hg exposure ≥6.0 µg/g showed associated with no regular income (PR: 1.3; CI95%: 1.0–1.8), high blood pressure (PR: 1.6; CI95%: 1.3–2.1) and was more prominent in Sawré Aboy village (PR: 1.8; CI95%: 1.3–2.3). For women of childbearing age, the Hg exposure ≥6.0 µg/g was associated with high blood pressure (PR: 1.9; CI95%: 1.2–2.3), with pregnancy (PR: 1.5; CI95%: 1.0–2.1) and was more prominent among residents in Poxo Muybu (PR: 1.9; CI95%: 1.0–3.4) and Sawré Aboy (PR: 2.5; CI95%: 1.4–4.4) villages. Our findings suggest that chronic mercury exposure causes harmful effects to the studied indigenous communities, especially considering vulnerable groups of the population, such as women of childbearing age. Lastly, we propose to stop the illegal mining in these areas and develop a risk management plan that aims to ensure the health, livelihoods, and human rights of the indigenous people from Amazon Basin.

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