Do General Dimensions of Quality of Life Add Clinical Value to Symptom Data?

Background Fatigue and pain are prevalent symptoms of multiple sclerosis (MS) and frequent complaint in MS patients, which reduce their quality of life. This study aimed to assess the effect of massage therapy on pain and fatigue in MS Patients. Method The original and Persian databases were searched included PubMed, web of science, embase, ovid, scopus, and the Cochrane Library, SID, and Iranedex from inception to November 2020. Studies that reported the effect of massage on fatigue and pain were included. Two investigators extracted all relevant data, independently. For deriving analysis, mean difference (MD) and standardized mean difference (SMD) were used. Result Ten studies were eligible acoording criteria. The effect of massage on fatigue showed significant improvement (−1.62; 95% CL −2.40, −0.83; p < .00001), also results of the systematic review showed a significant reduction in pain severity. Conclusion Massage as a complementary and non-pharmacological therapy might have been associated with alleviating fatigue and pain in M.S. patients. Based on the current study, massage intervention for MS patients could have possible clinical value for palliating pain and fatigue and improving quality of life; however, this matter needs further and more significant trial studies.

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AB0698 REAL CLINICAL PRACTICE IN THE CONTROL OF REPORTED OUTCOMES BY THE PATIENT (PROS) DIAGNOSED WITH PSORIATIC ARTHRITIS AND/OR ANKYLOSING SPONDYLITIS WHO BEGIN TREATMENT WITH SECUKINUMAB. A PROSPECTIVE MULTICENTRIC STUDY.

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.2795 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 1645.1-1645

Author(s):

J. J. Lerma ◽

A. Gracia ◽

A. Perez ◽

A. Rueda ◽

C. Molina ◽

...

Keyword(s):

Quality Of Life ◽

Psoriatic Arthritis ◽

Statistical Significance ◽

Value Added ◽

Severity Index ◽

Paired Data ◽

Clinical Value ◽

Multicentric Study ◽

Sleeping Problems

Background:Objectives:Analyse the effect of secukinumab in terms of the patient´s own variables, specifically: fatigue, sleep, pain and quality of life in patients with psoriatic arthritis or spondyloarthritis.Methods:A multicentric longtitudinal observational prospective study was carried out at 6 months in patients who begin treatment with secukinumab. At the start and after 6 months the following data was collected on the outcome: pain through an visual analogue scale (VAS), fatigue using the FACIT-fatigue scale, sleeping problems using the insomnia severity index (ISI) and quality of life with the EuroQol-3L-5D and the PsAQoL.The sample can be described in terms of the distribution of the variables through measures of central tendency.It was analysed if the change after 6 months was statistically relevant using Student´s t-test for paired data in the case of FACIT, VAS, PsAQoL and ISI and chi-squared for the dimensions of the EQ-5D. The size of the effect of each of the measurements taken was calculated using Cohen’s D. the results are given grouped by disease and globally. The analysis was carried out using Stata v12 (College Station Tx, USA)Results:In table 1, the changes in the scales of normal distribution can be seen. Apart from general VAS, all the scales experience significant relevant changes. The PROs preferred by the patient with the best therapeutic response is the quality of sleep. The adjustment of the regression models does not produce changes in the results, apart from small adjustments to the condidence intervals (final column table 1). The subdomain in which the most significant change in the EQ-5D is produced is in that of pain and discomfort.Conclusion:After 6 months patients who begin treatment with secukinumab, present with improvements in all sizes of the effects of the treatment in the various studied scales. The improvement achieves global and generalised statistical significance after 6 months of study. The greatest effect is on sleep, quality of life and fatigue.The measurements of the outcomes reported by the patients are a clinical value added to our objective evaluations of the health and activity of the disease, and allow us, in a more integrated and comprehensive manner, to undertake a more exact and close evaluation of their state of health and wellbeing.Disclosure of Interests:JUAN JOSE LERMA: None declared, Antonio Gracia: None declared, Antonio Perez: None declared, Amalia Rueda: None declared, Clara Molina: None declared, M. Dolores Pastor: None declared, Isabel Balaguer Trull: None declared, Inmaculada Valiente: None declared, Cristina Campos Fernández: None declared, Javier Calvo: None declared, Loreto Carmona Grant/research support from: Novartis Farmaceutica, SA, Pfizer, S.L.U., Merck Sharp & Dohme España, S.A., Roche Farma, S.A, Sanofi Aventis, AbbVie Spain, S.L.U., and Laboratorios Gebro Pharma, SA (All trhough institution)

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Study on the Effect of Pain Nursing Intervention in ENT Wards

Journal of Clinical and Nursing Research ◽

10.26689/jcnr.v5i1.1781 ◽

2021 ◽

Vol 5 (1) ◽

Author(s):

Baoyi Huang ◽

Fengmei Xu ◽

Hongmei Kuang

Keyword(s):

Quality Of Life ◽

Severe Pain ◽

Nursing Intervention ◽

Control Group ◽

Nursing Interventions ◽

Observation Group ◽

Clinical Value ◽

Clinical Nursing ◽

And Control

Objective: To explore the effectiveness of pain nursing interventions for patients in ENT. Methods: The 200 ENT patients admitted from March 2018 to March 2020 were divided into observation group (n=100) and control group (n=100). The control group was used conventional clinical nursing methods, and the observation group received pain nursing intervention as a comparison with the control group. Results: The observation group had 83 cases, 14 cases and 3 cases of mild, moderate and severe pain, respectively, while the control group are of 43 cases, 43cases and 14 cases. Nursing intervention can significantly reduce the pain of patients after otolaryngology surgery, improve the quality of life of patients, and has high clinical value for application.

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A Randomised Controlled Trial of the Effect of Esmarch Tourniquet Use on Blood Loss, Bruising and Quality of Life in Elective Varicose Vein Surgery

Phlebology The Journal of Venous Disease ◽

10.1177/026835550201700104 ◽

2002 ◽

Vol 17 (1) ◽

pp. 10-12

Author(s):

A. Fowler ◽

M. Stechman ◽

D. Mitchell

Keyword(s):

Quality Of Life ◽

Blood Loss ◽

Varicose Vein ◽

Controlled Trial ◽

Randomised Trial ◽

Varicose Vein Surgery ◽

Clinical Value ◽

Prospective Randomised Trial ◽

Randomised Controlled

Objective: To assess the effect of tourniquet use on bleeding, bruising and quality of life in varicose vein surgery. Method: A prospective randomised trial of 49 patients undergoing varicose vein surgery was carried out. All patients were having single leg surgery as a day case. Blood loss was assessed by weighing swabs. Bruising was measured at 10 days, and quality of life assessed with SF36 questionaires. Synthesis: In the tourniquet group blood loss was significantly reduced but not the area of bruising. The SF36 scores showed deterioration in the non-tourniquet group at 10 days but this was not present at 6 weeks. We saw no complications of tourniquet use but the study was limited by disappointing recruitment reducing the power. Conclusion: Tourniquet use may be of clinical value. A larger study is required to assess the significance.

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Analysis of the Effect of Advanced Nursing on the Quality of Life and the Prevention of Complications in Patients with Breast Cancer Undergoing PICC Chemotherapy

Tobacco Regulatory Science ◽

10.18001/trs.7.5.77 ◽

2021 ◽

Vol 7 (5) ◽

pp. 1558-1563

Author(s):

Xiuzhen Hu ◽

Qun Yang ◽

Zhengyun Wang ◽

Xuyun Hu

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Negative Emotion ◽

Nursing Intervention ◽

Psychological Status ◽

Control Group ◽

Study Group ◽

Clinical Value ◽

Significant Difference

Objective: To investigate the effect of advanced nursing on the quality of life and the prevention of complications in patients with breast cancer undergoing PICC (Peripherally Inserted Central Catheter) chemotherapy. Methods: From January 2017 to January 2020, 98 patients with breast cancer undergoing PICC chemotherapy in our hospital were divided into control group and study group by random sampling. The patients were given routine nursing and advanced nursing intervention on the basis of routine nursing. The psychological status, complications and quality of life of the patients were compared. Results: There was no significant difference in HAMA, HAMD score and QLQ-30 score before nursing (P > 0.05). The scores of HAMA and HAMD in the study group after nursing were lower than those in the control group (P < 0.05), the scores of QLQ-30 were higher than those in the control group (P < 0.05), and the complication rate was lower than that in the control group (P < 0.05). Conclusion: The intervention of advanced nursing mode in patients with breast cancer treated with PICC chemotherapy can effectively alleviate the influence of negative emotion on chemotherapy, reduce the occurrence of complications and improve the quality of life. This mode has high clinical value.

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Diagnostic capabilities of the WHOQOL-100 Questionnaire in Life’s Quality assessment for patients with coronary heart disease and atrial fibrillation

Progress in Health Sciences ◽

10.5604/01.3001.0014.1911 ◽

2020 ◽

Vol 10 (1) ◽

pp. 13-18

Author(s):

V. A. Snezhitskiy ◽

M.Yu Surmach ◽

S.L Boyko

Keyword(s):

Quality Of Life ◽

Medical Journal ◽

Cardiovascular Diseases ◽

Social Relations ◽

Practical Importance ◽

Circulatory System ◽

Social Significance ◽

Clinical Value ◽

Circulatory System Diseases

Introduction: Circulatory system diseases have high medical and social significance, therefore, the study of the quality of life associated with health for cardiological patients is of great practical importance. A large number of methods for assessing the quality of life are known, but not all methods have a methodological justification in cardiology and practical approbation. The aim of the work was to assess the clinical value of the WHOQOL-100 questionnaire for a group of patients with cardiovascular diseases. Materials and methods: The work methodology is presented by the analysis of RISC, Springer Link, Oxford University Press, New England Medical Journal, British Medical Journal, Elsevier SCOPUS database, EBSCO platform, as a result, the WHOQOL100 method was justified for use. Results: It has been established that the psychological field (the ratio of positive and negative emotions) and the sphere of social relations with an emphasis on practical social support are components of the quality of life, which can be considered as key vectors of social rehabilitation and criteria for the social effectiveness of treating patients with cardiovascular diseases. Conclusion: The international questionnaire WHOQOL-100 is recommended for use for cardiological patients with the subsequent analysis of the whole profile of quality of life.

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The Potential Clinical Value of Quality-of-Life Information

Medical Care ◽

10.1097/00005650-200206001-00009 ◽

2002 ◽

Vol 40 (Supplement) ◽

pp. III-56-III-62 ◽

Cited By ~ 7

Author(s):

Colleen A. McHorney

Keyword(s):

Quality Of Life ◽

Clinical Value

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The Home-Based Sleep Laboratory

Journal of Parkinson s Disease ◽

10.3233/jpd-202412 ◽

2021 ◽

pp. 1-6

Author(s):

Yael Hanein ◽

Anat Mirelman

Keyword(s):

Quality Of Life ◽

Sleep Quality ◽

Sleep Disturbances ◽

State Of The Art ◽

Sleep Laboratory ◽

Clinical Value ◽

Home Based ◽

Precise Mapping ◽

Clinical Adoption

Sleep disturbances are prevalent in neurodegenerative diseases in general, and in Parkinson’s disease (PD) in particular. Recent evidence points to the clinical value of sleep in disease progression and improving quality of life. Therefore, monitoring sleep quality in an ongoing manner at the convenience of one’s home has the potential to improve clinical research and to contribute to significantly better personalized treatment. Further, precise mapping of sleep patterns of each patient can contribute to a better understanding of the disease, its progression and the appropriate medical treatment. Here we review selective, state-of-the-art, home-based devices for assessing sleep and sleep related disorders. We highlight the large potential as well as the main challenges. In particular, we discuss medical validity, standardization and regulatory concerns that currently impede widespread clinical adoption of existing devices. Finally, we propose a roadmap with the technological and scientific steps that are required to impact PD research and treatment.

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Evaluation correlation between quality of life and global functioning in schizophrenic patients in mazandaran state

European Psychiatry ◽

10.1016/s0924-9338(11)73106-6 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 1401-1401

Author(s):

S.H. Hosseini ◽

M. KarkhanehYusefi

Keyword(s):

Quality Of Life ◽

Interpersonal Relationship ◽

Living Condition ◽

Clinical Value ◽

Global Functioning ◽

Quality Of Life Scale ◽

Life Scale ◽

Schizophrenic Patients ◽

Instrumental Role

BackgroundSchizophrenia is a disorder, which has the most regression in behavioural, occupational and psychiatry aspects, and it is also important for this patients. the main purpose of this study is to evaluate. The quality of life and global function of schizophrenia patients.Method100 schizophrenia patients (with DSM-IV-TR) who had a history of at least 10 years from the beginning of the disorder were collected. Demographic characteristics, type of schizophrenia, living condition and the quality of life scale (QLS) including interpersonal relationship instrumental role, intra psychic foundation and common objects and activities, were filled. Patients’ general functions were evaluated with GAF.ResultsIn this study 67% were men and 51% were women. They were residual (55%), Paranoid (11%)and undifferentiated (33%) schizophrenia. They lived in institute (67%) and with their families (28%). The significant association were found to be between married and singles patients in instrumental role (F, 2, 97), P > ./.5) but there weren’t found any association in other domains also the significant. Correlation were found between undifferentiated and paranoid patients in interpersonal relationship (F, 2, 97), P > ./.5).but there weren’t any correlation in intrapsychic foundation and common objects and activities domains. Also there were significant association in GAF (F, 3, 98), P > ./.5)between uneducated and educated participants. The Mean of five domains and genders didn’t have any association together.ConclusionSchizophrenia patients’ quality of life is low. which showed the value and reliability of Global Assessment Functioning that usually used for every psychiatrics’ patients for V axis clinical diagnosis and indicated the clinical value of this scale.

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