Diseases of the autonomic nervous system

2020 ◽  
pp. 6150-6165
Author(s):  
Christopher J. Mathias ◽  
David A. Low
Keyword(s):  
Diabetes Mellitus ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Whole Body ◽  
Hydroxylase Deficiency ◽  
Autonomic Nervous ◽  
System P ◽  
Cord Injury ◽  
Autonomic Disorders ◽  
Efferent Pathways

The autonomic nervous system innervates all organs, producing predominantly involuntary and automatic actions that are mediated by two principal efferent pathways, the sympathetic and parasympathetic, which are neurochemically and anatomically distinct. Numerous synaptic relays and neurotransmitters allow the autonomic control of organ function at local and central levels to be integrated with the requirements of the whole body. The peripheral and central components of the autonomic nervous system are frequently affected by diseases, conditions, or toxins. Autonomic disorders are described as (1) primary—without defined cause, including multiple system atrophy and acute/subacute dysautonomias; or (2) secondary—with specific defects or as a consequence of other conditions, including diabetes mellitus, Riley–Day syndrome, amyloid neuropathy, dopamine β‎-hydroxylase deficiency, spinal cord injury, and many drugs.

Diseases of the autonomic nervous system

2010 ◽  
pp. 5055-5068
Author(s):  
Christopher J. Mathias ◽  
David A. Low
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Autonomic Control ◽  
Whole Body ◽  
Organ Function ◽  
Autonomic Nervous ◽  
System P ◽  
Efferent Pathways

The autonomic nervous system innervates all organs, producing predominantly involuntary and automatic actions that are mediated by two principal efferent pathways, the sympathetic and parasympathetic, which are neurochemically and anatomically distinct. Numerous synaptic relays and neurotransmitters allow the autonomic control of organ function at local and central levels to be integrated with the requirements of the whole body....

Autonomic Nervous System

2017 ◽  
pp. 311-348
Author(s):  
Eduardo E. Benarroch ◽  
Jeremy K. Cutsforth-Gregory ◽  
Kelly D. Flemming
Keyword(s):  
Nervous System ◽  
Smooth Muscle ◽  
Autonomic Nervous System ◽  
Regulation System ◽  
Exocrine Glands ◽  
Neurologic Diseases ◽  
Autonomic Nervous ◽  
Visceral Organs ◽  
System P ◽  
Autonomic Disorders

The autonomic nervous system is a critical effector of an internal regulation system that controls functions necessary for survival. Autonomic outputs regulate the activity of the heart; the smooth muscle of the blood vessels, pupil, and visceral organs; and the exocrine glands. The autonomic nervous system includes 3 subdivisions: the sympathetic, parasympathetic, and enteric nervous systems. Autonomic disorders may be prominent manifestations of several neurologic diseases and, in some cases, may be valuable in localizing lesions in the nervous system.

scholarly journals The Effect of Osteopathic Correction to the Vegetative Status in Patients with Diabetes Mellitus of 2nd Type

2015 ◽  
pp. 21-28 ◽  
Author(s):  
A. Fudashkin ◽  
B. Usupbekova
Keyword(s):  
Diabetes Mellitus ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Autonomic Nervous ◽  
Efficiency Assessment ◽  
Functional Efficiency ◽  
Autonomic Disorders ◽  
Autonomic Dysfunctions ◽  
Patients With Diabetes ◽  
Vegetative Status

The results of instrumental and functional efficiency assessment of osteopathic correction for diabetes mellitus of 2nd type autonomic dysfunctions are presented in this article. Osteopathic examination data are provided and common somatic dysfunctions are identified. Osteopathic correction of the autonomic disorders is associated with the balancing process for both sympathetic and parasympathetic divisions of autonomic nervous system.

Distribution of the preferred clothing pressure over the whole body

2018 ◽  
Vol 89 (11) ◽  
pp. 2187-2198 ◽  
Author(s):  
Tamaki Mitsuno ◽  
Ayaka Kai
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Hydrostatic Pressure ◽  
Body Part ◽  
Whole Body ◽  
Elastic Band ◽  
Autonomic Nervous ◽  
Pressure Load ◽  
Calibration Methods ◽  
Clothing Pressure

A system for measuring clothing pressure employing a renewed hydrostatic pressure-balancing method was examined using three calibration methods. All methods revealed an almost perfectly linear Y = X relation for the pressure load (X) and the reading of the system (Y). In the application, the distributions of elastic band pressure were examined on 21 planes from head to foot. The preferred elastic band pressures of the leg and arm were significantly higher than those of the neck and abdomen. These results are due to the large presence of the autonomic nervous system at the surfaces of the neck and abdomen. In the area of the abdomen, the preferred elastic band pressure was higher from the mammilla to the shoulder than for the anteroposterior midlines. The development of compression ware must consider appropriate tightening for each body part.

scholarly journals Brain permeable AMPK activator R481 raises glycemia by autonomic nervous system activation and amplifies the counterregulatory response to hypoglycemia in rats

2019 ◽  
Author(s):  
Ana M. Cruz ◽  
Yasaman Malekizadeh ◽  
Julia M. Vlachaki Walker ◽  
Paul G. Weightman Potter ◽  
Katherine Pye ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Hepatic Glucose Production ◽  
Glucose Production ◽  
Ventromedial Hypothalamus ◽  
Whole Body ◽  
Ampk Activation ◽  
Autonomic Nervous ◽  
Glucose Levels

ABSTRACTAMP-activated protein kinase (AMPK) is a critical cellular and whole body energy sensor activated by energy stress, including hypoglycemia, which is frequently experienced by people with diabetes. Previous studies using direct delivery of an AMPK activator to the ventromedial hypothalamus (VMH) in rodents increased hepatic glucose production. Moreover, recurrent glucoprivation in the hypothalamus leads to blunted AMPK activation and defective hormonal responses to subsequent hypoglycemia. These data suggest that amplifying AMPK activation may prevent or reduce frequency hypoglycemia in diabetes. We used a novel brain-permeable AMPK activator, R481, which potently increased AMPK phosphorylation in vitro. R481 significantly increased peak glucose levels during glucose tolerance tests in rats, which were attenuated by treatment with AMPK inhibitor SBI-0206965 and completely abolished by blockade of the autonomic nervous system. This occurred without altering insulin sensitivity measured by hyperinsulinemic-euglycemic clamps. Endogenous insulin secretion was not altered by R481 treatment. During hyperinsulinemic-hypoglycemic clamp studies, R481 treatment reduced exogenous glucose requirements and amplified peak glucagon levels during hypoglycemia. These data demonstrate that peripheral administration of the brain permeable AMPK activator R481 amplifies the counterregulatory response to hypoglycemia in rats, which could have clinical relevance for prevention of hypoglycemia.

Abstract P129: Role of the Autonomic Nervous System in Remote Postconditioning in Humans

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Rupert P Williams ◽  
Michael I Okorie ◽  
Harminder Gill ◽  
John E Deanfield ◽  
Raymond J MacAllister ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Whole Body ◽  
Limb Ischaemia ◽  
Protective Effects ◽  
Blood Pressure Cuff ◽  
Autonomic Nervous ◽  
Pressure Cuff ◽  
Remote Postconditioning

Brief periods of ischaemia activate systemic mechanisms that induce whole-body tolerance to subsequent prolonged and injurious ischaemia. This phenomenon, remote ischaemic preconditioning (RIPC), is sufficiently acute to reduce ischaemia-reperfusion (IR) injury even when applied simultaneously with injurious ischaemia. This aspect of RIPC is termed remote postconditioning (RPostC). We have previously demonstrated a role for the autonomic nervous system in RIPC. Using an in vivo model of endothelial IR injury, we determined if RPostC is dependent on adrenergic autonomic mechanisms. Vascular ultrasound was used to assess endothelial function in healthy volunteers by measuring dilatation of the brachial artery in response to increased blood flow during reactive hyperaemia (flow-mediated dilatation; FMD). Endothelial IR injury was induced by 20 min of upper limb ischaemia (inflation of a blood pressure cuff to 200 mm Hg) followed by reperfusion. RPostC was induced by applying 2 cycles of 5 minutes ischaemia and 5 minutes reperfusion on the leg during arm ischaemia (via a second blood pressure cuff). In order to determine the dependence of RPostC on autonomic activation, we administered the alpha adrenoceptor blocker phentolamine (0.2– 0.7mg/min, intravenously) during the application of the RPostC stimulus. FMD was determined before ischaemia and at 20 minutes of reperfusion. FMD (percentage change from baseline diameter) was compared statistically by ANOVA. IR alone caused a significant reduction in FMD (5.9±0.7% pre- versus 2.2±0.4% post-IR, n=9, P<0.001). This reduction was prevented by RPostC (5.8±0.4% pre- versus 5.4±0.3% post-IR, n=8, P>0.05). Systemic phentolamine blocked the protective effects of RPostC (FMD 6.1±0.5% pre- versus 2.0±0.3% post-IR, n=7, P<0.001). These data indicate, for the first time in humans, that protection from RPostC depends on preservation of adrenergic signalling. Alpha blockade neutralises one of the endogenous mechanisms of ischemic protection in humans; the clinical consequences of this remain to be determined.

Autonomic Nervous System

2021 ◽  
pp. 158-168
Author(s):  
Jeremy K. Cutsforth-Gregory
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Insular Cortex ◽  
Anterior Cingulate ◽  
Nucleus Ambiguus ◽  
Ventrolateral Medulla ◽  
Autonomic Nervous ◽  
Parasympathetic Nerves ◽  
System P ◽  
Functional Components

The autonomic nervous system is involved in many important unconscious body functions. It is critical for maintaining the internal environment in response to changes in the external environment. The autonomic nervous system consists of peripheral components (sympathetic and parasympathetic nerves and ganglia) and central components (ventrolateral medulla, nucleus ambiguus, nucleus of the solitary tract, periaqueductal gray, anterior cingulate gyrus, insular cortex, amygdala, and hypothalamus). This chapter briefly reviews the anatomy and functional components of the autonomic nervous system and several anatomical clinical correlations.

The Autonomic Nervous System

Neuroanatomy ◽  
2017 ◽  
pp. 117-138
Author(s):  
Adam J Fisch
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Cardiac Rhythm ◽  
Parasympathetic Nervous System ◽  
Baroreceptor Reflex ◽  
Urinary System ◽  
Autonomic Nervous ◽  
System P ◽  
Hair Fiber ◽  
Sympathetic Nervous

This chapter provides an overview of the autonomic nervous system and respective instructions for drawing its various components. These include the, parasympathetic nervous system, sympathetic nervous system, lower urinary system, baroreceptor reflex, respiration, and digestive tract. The chapter discusses the various functions of elements of these systems, and it presents conditions and illnesses specifically related to disorders in elements of the autonomic nervous system, such as cardiac rhythm abnormalities (arrhythmias), respiratory failure, gut dysmotility, bladder dysmotility, and skin manifestations, such as hair fiber loss and sweating.

Gravity

How to Land ◽  
2018 ◽  
pp. 107-138
Author(s):  
Ann Cooper Albright
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Physical Function ◽  
Two Dimensional ◽  
Daily Lives ◽  
Autonomic Nervous ◽  
System P ◽  
The World ◽  
Ubiquitous Presence

This chapter weaves an in-depth discussion of the physical function of releasing our bodies into the support of gravity with an analysis of how that experience can serve as an important stability in our daily lives. It begins by reviewing the crucial distinction between collapsing and yielding in order to demonstrate how the same force that draws us to the ground can also sponsor our action in the world, helping us find a sense of resistance and agency. In addition, gravity can provide a useful counterbalance to the ubiquitous presence of two-dimensional screens in our lives. By allowing us to experience weight, gravity is key to our sense of grounding, linking inhalation with exhalation, sky to earth, as well as the sympathetic and parasympathetic aspects of our autonomic nervous system.

Sign in / Sign up

Export Citation Format

Share Document