Delirium

2020 ◽  
pp. 425-436
Author(s):  
David Meagher ◽  
Cara Daly ◽  
Dimitrios Adamis
Keyword(s):  
Antipsychotic Agents ◽  
Careful Consideration ◽  
Cognitive Testing ◽  
Everyday Practice ◽  
Pharmacological Intervention ◽  
Careful Attention ◽  
Healthcare Outcomes ◽  
Underlying Causes ◽  
The Relationship

Delirium is a common, complex neuropsychiatric syndrome that occurs in approximately one in five hospitalized patients. It is associated with a range of adverse healthcare outcomes that are independently predicted by the severity and duration of delirium. Typically 50% or more of cases of delirium are missed, misdiagnosed, or diagnosed late in everyday practice. However, routine systematic cognitive testing aligned to formal screening for delirium in high-risk cases can improve detection in everyday practice. The relationship between delirium and dementia is complex; dementia is a potent risk factor for delirium and 50% of delirium occurs in the context of a pre-existing dementia, but evidence also indicates that the occurrence of delirium can accelerate the course of dementia and that many cases of delirium are followed by long-term cognitive impairment. Delirium is highly preventable, with a third of cases avoidable by addressing a variety of patient, illness, and treatment factors. Treatment of incident delirium requires careful consideration of underlying causes, aggravating environmental factors, and prudent use of pharmacological strategies, with antipsychotic agents the preferred pharmacological intervention. Careful attention to post-delirium care can minimize functional loss, address any psychological sequelae, and reduce the risk of further episodes.

Novel Pharmacotherapeutics for Stress-Related Disorders

2019 ◽  
pp. 642-672
Author(s):  
Jamie E. Mondello ◽  
Jenny E. Pak ◽  
Dennis F. Lovelock ◽  
Terrence Deak
Keyword(s):  
Mental Health Problems ◽  
Drug Efficacy ◽  
Careful Consideration ◽  
Pharmacological Intervention ◽  
Pharmacological Interventions ◽  
Diverse Range ◽  
Disease States ◽  
Efficacy Trials ◽  
Participant Selection ◽  
The Relationship

Most mental health problems associated with psychological distress originate with activation of centrally regulated stress pathways, yet a diverse range of central nervous system and somatic disease states can be influenced by exposure to severe or unrelenting stress. The goal of this chapter is to provide a conceptual framework to guide the development of pharmacological intervention strategies. We propose that careful consideration of the relationship between the timing of stressful life experiences, pharmacological intervention, and the ultimate expression of disease symptomatology is critical for the development of pharmacological interventions to treat stress-related disorders. We review a range of physiological systems that are known to be activated by stress, offering potentially new targets for drug development efforts, and argue that participant selection is a key predictor of drug efficacy trials. In doing so, we point toward inflammatory signaling pathways as a potential final common mediator of multiple stress-related disease states.

Reconsidering the Effects of Marital Disruption

1994 ◽  
Vol 15 (2) ◽  
pp. 173-190 ◽  
Author(s):  
FRANK F. FURSTENBERG ◽  
JULIEN O. TEITLER
Keyword(s):  
Longitudinal Data ◽  
Family Conflict ◽  
Family Formation ◽  
Well Being ◽  
Marital Disruption ◽  
Careful Consideration ◽  
Family Characteristics ◽  
Economic Attainment ◽  
The Relationship

This article identifies predivorce individual and family characteristics that explain a portion of the effect of parental separation on the long-term well-being of children. Using longitudinal data from the National Survey of Children (NSC), the authors discuss how much of the relationship between a separation and measures of adult well-being (including educational and economic attainment, patterns of family formation, delinquency, and psychological well-being) is due to selectivity of parents into more fragile marriages and to family conflict that often precedes the physical departure of a parent from the household. The results of the study indicate that divorce is associated with some outcomes, although much of its putative effect diminishes when predivorce factors are accounted for. The authors suggest that researchers give more careful consideration to the processes leading up to a separation as part of the divorce experience of children.

scholarly journals FAKTOR – FAKTOR YANG MEMENGARUHI HARGA SAHAM PERUSAHAAN PERKEBUNAN DI BURSA EFEK INDONESIA TAHUN 2008-2016

2018 ◽  
Vol 8 (2) ◽  
pp. 199-211
Author(s):  
Ifan Rizky Kurniyanto ◽  
Bayu Krisnamurthi
Keyword(s):  
Stock Prices ◽  
Stock Price ◽  
Careful Consideration ◽  
Accurate Information ◽  
Plantation Company ◽  
Stock Market Investors ◽  
The Right ◽  
Relationship Of ◽  
The Relationship

Capital markets allows the plantation companies to obtain long-term sources of funding for business expansion. To Invest in the stock market investors require careful consideration of accurate information to determine the relationship of variables that cause the fluctuation of the company's stock price to be purchased. Knowing the influence of these variables, investors can choose a strategy to determine the right company as a place to invest. The purpose of this study is to analyze technically and fundamentally shares of plantation companies that have been listed on the BEI in period of 2008-2016. Research method using panel data and Ipot Ultima. The results of this study showed that through fundamental analysis it is known that ROA, Inflation, Exchange Rate, and BI Rate and AR1 have a significant influence (Pvalue <0.05) on stock prices while CR, DER, TOTA, PER, NPM have no significant effect on stock price plantation. Through technical analysis it is known that the movement of plantation company in MA 3025 is sideway.

Models of Private Practice

2017 ◽  
pp. 15-21
Author(s):  
Jeffrey Zimmerman
Keyword(s):  
Private Practice ◽  
Careful Consideration ◽  
Group Practice ◽  
Practice Model ◽  
Solo Practice ◽  
Equity Ownership ◽  
Practice Culture ◽  
Relationship Of ◽  
The Relationship

There are many choices when embarking in private practice, and they deserve careful consideration because they are both fundamental and complex. This chapter describes models of solo practice and group practice. Autonomy, decision making and governance, the practice culture, and the relationship of the clinician to the practice are examined and discussed; they vary depending on the practice model. Different approaches to establishing compensation, benefits, incentives, and equity ownership are described. The chapter highlights the importance of considering the long-term aspects of a practice environment that is aligned with one’s professional development and personal needs so as to create a sense of “fit.”

scholarly journals An Assessment of Local People’s Support to Private Wildlife Conservation: A Case of Save Valley Conservancy and Fringe Communities, Zimbabwe

Scientifica ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-11
Author(s):  
Given Matseketsa ◽  
Billy B. Mukamuri ◽  
Never Muboko ◽  
Edson Gandiwa
Keyword(s):  
Wildlife Conservation ◽  
Local People ◽  
Systematic Sampling ◽  
Term Survival ◽  
The People ◽  
Fringe Communities ◽  
Underlying Causes ◽  
Multistage Sampling ◽  
The Relationship

The long-term survival of a protected area (PA) may depend to a greater extent on the goodwill and support of the people residing around it. This study assessed local people’s support for private sector driven wildlife conservation in Zimbabwe, using the Save Valley Conservancy (SVC) as a case. Specifically, the objectives of the assessment were threefold: (i) to establish perceptions on the current nature of the relationship between SVC and people living on its edge, (ii) to ascertain the proximate and underlying causes of local resistance to SVC, and (iii) to identify strategies local people employ to resist SVC conservation efforts. Data were collected through a household questionnaire survey during the month of April, 2018. In addition, photographs showing the nature of vandalism and sabotage imposed on the SVC ecosystem by fringe communities were also collected, as part of evidential data. A multistage sampling method was adopted, and this combined purposive sampling to select study wards: random sampling to select villages and systematic sampling to select households (n=71). Our results show that local people rate the current relationship between them and SVC owners as bad, i.e., undesirable interaction. The nature of this perceived bad relationship is attributed to a host of factors, key among them being, lack of wildlife-related benefits and escalation of wildlife-induced costs, which are crucial in determining local community’s support for conservation. We conclude that the studied local community’s support for private nature conservation is marginal; hence, there is a need for increased efforts by SVC owners to devise realistic incentives including an active engagement of local communities so that they cooperate with conservation efforts.

Practical High Resolution Microscopy

1968 ◽  
Vol 26 ◽  
pp. 302-303
Author(s):  
P. A. Marsh ◽  
T. Mullens ◽  
D. Price
Keyword(s):  
High Resolution ◽  
Magnetic Fields ◽  
Low Frequency ◽  
Resolving Power ◽  
Careful Attention ◽  
Electron Microscopes ◽  
The Relationship ◽  
High Resolution Microscopy ◽  
New Facilities

It is possible to exceed the guaranteed resolution on most electron microscopes by careful attention to microscope parameters essential for high resolution work. While our experience is related to a Philips EM-200, we hope that some of these comments will apply to all electron microscopes.The first considerations are vibration and magnetic fields. These are usually measured at the pre-installation survey and must be within specifications. It has been our experience, however, that these factors can be greatly influenced by the new facilities and therefore must be rechecked after the installation is completed. The relationship between the resolving power of an EM-200 and the maximum tolerable low frequency interference fields in milli-Oerstedt is 10 Å - 1.9, 8 Å - 1.4, 6 Å - 0.8.

Multi-Center Calibration of the Second Reference Material for Thromboplastin, Rabbit, Plain, Coded CRM 149R

1991 ◽  
Vol 65 (03) ◽  
pp. 263-267 ◽  
Author(s):  
A M H P van den Besselaar ◽  
R M Bertina
Keyword(s):  
Reference Material ◽  
Standard Error ◽  
Standard Errors ◽  
Sensitivity Index ◽  
Long Term Stability ◽  
Significant Bias ◽  
The Mean ◽  
The Relationship ◽  
International Sensitivity Index

SummaryIn a collaborative trial of eleven laboratories which was performed mainly within the framework of the European Community Bureau of Reference (BCR), a second reference material for thromboplastin, rabbit, plain, was calibrated against its predecessor RBT/79. This second reference material (coded CRM 149R) has a mean International Sensitivity Index (ISI) of 1.343 with a standard error of the mean of 0.035. The standard error of the ISI was determined by combination of the standard errors of the ISI of RBT/79 and the slope of the calibration line in this trial.The BCR reference material for thromboplastin, human, plain (coded BCT/099) was also included in this trial for assessment of the long-term stability of the relationship with RBT/79. The results indicated that this relationship has not changed over a period of 8 years. The interlaboratory variation of the slope of the relationship between CRM 149R and RBT/79 was significantly lower than the variation of the slope of the relationship between BCT/099 and RBT/79. In addition to the manual technique, a semi-automatic coagulometer according to Schnitger & Gross was used to determine prothrombin times with CRM 149R. The mean ISI of CRM 149R was not affected by replacement of the manual technique by this particular coagulometer.Two lyophilized plasmas were included in this trial. The mean slope of relationship between RBT/79 and CRM 149R based on the two lyophilized plasmas was the same as the corresponding slope based on fresh plasmas. Tlowever, the mean slope of relationship between RBT/79 and BCT/099 based on the two lyophilized plasmas was 4.9% higher than the mean slope based on fresh plasmas. Thus, the use of these lyophilized plasmas induced a small but significant bias in the slope of relationship between these thromboplastins of different species.

Risk Attitude and Corporate Investment under Output Market Uncertainty: Evidence from The Mekong River Delta, Vietnam

2016 ◽  
pp. 59-70
Author(s):  
Ninh Le Khuong ◽  
Nghiem Le Tan ◽  
Tho Huynh Huu
Keyword(s):  
Negative Relationship ◽  
Risk Attitude ◽  
Business Strategies ◽  
Risk Averse ◽  
Market Uncertainty ◽  
Firm Investment ◽  
Output Market ◽  
The Impact ◽  
The Relationship

This paper aims to detect the impact of firm managers’ risk attitude on the relationship between the degree of output market uncertainty and firm investment. The findings show that there is a negative relationship between these two aspects for risk-averse managers while there is a positive relationship for risk-loving ones, since they have different utility functions. Based on the findings, this paper proposes recommendations for firm managers to take into account when making investment decisions and long-term business strategies as well.

Financial Folly and Spain’s Black Legend

2017 ◽  
Author(s):  
Mauricio Drelichman ◽  
Hans-Joachim Voth
Keyword(s):  
Seventeenth Century ◽  
Economic History ◽  
Military Power ◽  
Great Flexibility ◽  
Loan Contracts ◽  
Historical Tradition ◽  
Black Legend ◽  
Contractual Obligations ◽  
The Relationship

This epilogue argues that Castile was solvent throughout Philip II's reign. A complex web of contractual obligations designed to ensure repayment governed the relationship between the king and his bankers. The same contracts allowed great flexibility for both the Crown and bankers when liquidity was tight. The risk of potential defaults was not a surprise; their likelihood was priced into the loan contracts. As a consequence, virtually every banking family turned a profit over the long term, while the king benefited from their services to run the largest empire that had yet existed. The epilogue then looks at the economic history version of Spain's Black Legend. The economic history version of the Black Legend emerged from a combination of two narratives: a rich historical tradition analyzing the decline of Spain as an economic and military power from the seventeenth century onward, combined with new institutional analysis highlighting the unconstrained power of the monarch.

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