Urothelial carcinomas of the upper urinary tract

2017 ◽  
Author(s):  
Tarek P. Ghoneim ◽  
Pierre Colin ◽  
Morgan Rouprêt
Keyword(s):  
Urinary Tract ◽  
Basic Research ◽  
Upper Urinary Tract ◽  
Evidence Based ◽  
Urothelial Carcinomas ◽  
New Concepts ◽  
Tumour Location ◽  
History Of ◽  
Based Medicine ◽  
Lower Urinary

Upper urinary tract urothelial carcinomas (UTUCs) are scarce and account for only 5-10% of urothelial carcinomas. The estimated annual incidence in western countries is approximately two new cases per 100,000 inhabitants. The natural history of UTUCs differs from that of bladder cancer; 60% of UTUCs are invasive at diagnosis compared to only 15% of bladder tumours. Apart from these epidemiological considerations, one could consider urothelial carcinomas as a whole and underline that the distinction between tumours of the upper and of the lower urinary tracts should be anatomically based (i.e. upper urinary tract vs. lower urinary tract). It is now obvious that strong differences exist regarding tumour location and behaviour between the upper and lower urinary tracts. The field of evidence-based medicine has grown largely in recent years for UTUCs, demonstrating that new insights, new concepts, new clinical and basic research, and new therapeutic findings are becoming readily available.

scholarly journals CHARACTERISTIC OF PEDIATRIC UROLITHIASIS PATIENTS IN ZAINOEL ABIDIN HOSPITAL

2018 ◽  
Vol 25 (1) ◽  
Author(s):  
Simon Natanel Yohanes ◽  
Dahril Dahril
Keyword(s):  
Urinary Tract ◽  
Family History ◽  
Lower Urinary Tract ◽  
Pediatric Patients ◽  
Upper Urinary Tract ◽  
Stone Disease ◽  
Age Group ◽  
Pediatric Urolithiasis ◽  
History Of ◽  
Lower Urinary

Objective: We conducted a study to describe the characteristics of pediatric urolithiasis patients in Zainoel Abidin Hospital, Aceh-Indonesia. Material & Methods: Between January 2013 and March 2016, we retrospectively reviewed the medical records of 16 pediatric patients with urolithiasis in Zainoel Abidin Hospital, Aceh-Indonesia. The patients were come from whole Aceh region and the variables are sex, age, family history of stone disease, and stone location. The data were described in graphics and tables. Results: From 16 pediatric urolithiasis patients, 9 patients (56.3%) were males and 7 patients (43.7%) were females. In 2013 there were 4 pediatric urolithiasis patients (1.2%), in 2014 there were 5 (1.6%), and in 2015 there were 3 (2.3%). From January – March 2016 there were 4 pediatric urolithiasis patients (4.5% of all urolithiasis patients). The mean age of all pediatric patients were 7.7 ± 5.5 years (1-17 years). The incidence of urolithiasis for group < 5 years of age were 6 patients (37.5%) with mean age of 2 ± 1.14 years (1-4 years), in 5–10 years age group, there were 4 patients (25.0%) with mean age 7 ± 2.16 years (5-10 years), and 11–18 years age group, there were 6 patients (37.5%) with mean age 13.8 ± 2.16 years (12-16 years). Stones were located in the upper urinary tract in 9 cases (56.3%), lower urinary tract in 6 cases (37.5%), and combine stone located in upper and lower urinary tract in 1 case (6.2%). There were 5 patients (31.3%) with family history of stone disease. Conclusion: Pediatric urolithiasis case in Aceh Province is slightly predominant in male children, with mean age of 7.7 ± 5.5 years (1-16 years). The most common age group is evenly distribute between <5 years old and 11-18 years old. The most common stone location is in the upper urinary tract.

Primary diffuse large B cell lymphoma (DLBCL) of the prostate presenting with lower urinary tract symptoms (LUTS)

2020 ◽  
Vol 13 (12) ◽  
pp. e236280
Author(s):  
Ayesha Nusrat ◽  
Syed Muhammad Nazim
Keyword(s):  
Urinary Tract ◽  
B Cell ◽  
Lower Urinary Tract ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Urinary Tract Symptoms ◽  
History Of ◽  
Large B Cell ◽  
Lower Urinary

Malignant lymphomas of the prostate are very rare tumours and are generally not considered in the clinical or pathological diagnosis of prostatic enlargement. We report a case of a 56-year-old man who presented with long-standing history of low back pain and a 2-month history of voiding lower urinary tract symptoms. He denied any history of urinary retention, trauma, catheterisation or any constitutional symptoms. Examination revealed no lymphadenopathy and hepatosplenomegaly. Digital rectal examination showed an irregular, moderately enlarged nodular prostate. His prostate-specific antigen was 1.54 ng/mL. MRI of the pelvis did not show any focal lesion apart from abnormal signal intensity in the central zone. Bone scan was negative. Transrectal ultrasound-guided prostate biopsy revealed diffuse large B cell lymphoma. Bone marrow biopsy and whole body positron emission tomography/CT were unremarkable. The patient achieved complete remission after receiving six cycles of R-CHOP chemotherapy.

Fear, history, stigma, and bias in the COVID-19 pandemic

2020 ◽  
Vol 18 (7) ◽  
pp. 177-182
Author(s):  
Kevin Kupietz, PhD ◽  
Lesley Gray, MPH
Keyword(s):  
Emergency Management ◽  
Disease Outbreaks ◽  
Social Effects ◽  
Evidence Based ◽  
Stigma And Discrimination ◽  
Emergency Managers ◽  
Global Pandemic ◽  
New Concepts ◽  
History Of ◽  
The Relationship

Introduction: The greatest enemy of a global pandemic is not the virus itself, but the fear, rumor, and stigma that envelopes people. This article explores the context and history of fear and stigma relating to pandemic, summarizing key actions to mitigate the harms during an active pandemic.Method: Our article draws from accounts in literature and journalist accounts documenting the relationship between infectious diseases and major disease outbreaks that have garnered fear and stigmatization. Results: Fear, stigma, and discrimination are not new concepts for pandemics. These social effects run the risk of diverting attention from the presenting disease and government responses. Reactions to fear, stigma, and discrimination risk sabotaging effective efforts to contain, manage, and eradicate the disease.Conclusion: Emergency managers have an important role in dispelling myths, disseminating appropriate and evidence-based information without exacerbating fears. Knowledge about the roots of fear and bias along with a good understanding of historical plagues and pandemics is vital to ensure those in the field of emergency management can effectively manage irrational fears.

scholarly journals Immune expression of E-cadherin and α, β and γ-Catenin adhesion molecules and prognosis for upper urinary tract urothelial carcinomas

2012 ◽  
Vol 38 (4) ◽  
pp. 466-473 ◽  
Author(s):  
Sabrina Thalita dos Reis ◽  
Katia Ramos Moreira Leite ◽  
Alcides Mosconi Neto ◽  
José Pontes Júnior ◽  
Nayara Izabel Viana ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Adhesion Molecules ◽  
Upper Urinary Tract ◽  
Urothelial Carcinomas ◽  
E Cadherin

A review of the contemporary management of upper urinary tract urothelial carcinoma

2017 ◽  
Vol 11 (1) ◽  
pp. 51-57
Author(s):  
Abhishek Reekhaye ◽  
Seshadri Sriprasad ◽  
Sanjeev Madaan
Keyword(s):  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Treatment Options ◽  
Treatment Strategies ◽  
Upper Urinary Tract ◽  
Rare Tumour ◽  
Endoscopic Techniques ◽  
Upper Tract ◽  
Urothelial Carcinomas ◽  
Urinary Tract Urothelial Carcinoma

Upper tract urothelial carcinoma (UTUC) is relatively rare and accounts for approximately 5% of all urothelial carcinomas. The estimated annual incidence of UTUC in Western countries is about two new cases per 100,000 inhabitants. The management of patients with upper tract urothelial carcinomas has changed significantly over the last decade with improved diagnostic techniques and treatment options. The gold-standard treatment used to be open radical nephroureterectomy with removal of the ipsilateral bladder cuff. The use of minimally invasive techniques for the diagnosis and management of upper urinary tract urothelial carcinoma is however expanding and has led to a paradigm shift in treatment strategies of upper tract urothelial carcinomas. In this article, we review the current diagnostic modalities and various endoscopic techniques being currently used in the management of this relatively rare tumour.

scholarly journals Upper urinary tract draining in acute gestational pyelonephritis: What for? When? For how long?

2019 ◽  
Vol 7 (3) ◽  
pp. 35-40 ◽  
Author(s):  
K. L. Lokshin
Keyword(s):  
Urinary Tract ◽  
Upper Urinary Tract ◽  
Scientific Data ◽  
Optimal Treatment ◽  
Evidence Based

Diagnosis and optimal treatment of urological conditions in pregnant have lots of controversy due to a lack of objective and evidence-based data. This is equally true in for acute gestational pyelonephritis patients, particularly in the context of indications for upper urinary tract ‘de-obstruction’/ draining, and catheter stay in situ time. This review is a compilation of current scientific data concerning upper urinary tract draining in patients with acute gestational pyelonephritis, as well analysis of our own data and results.

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