MO604DIFFERENCES IN THE EXTRACELLULAR BODY WATER/TOTAL BODY WATER (EBW/TBW) IN HEMODIALYSIS AND CHRONIC KIDNEY DISEASE PATIENTS. RELATIONSHIP WITH NUTRITIONAL PARAMETERS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Guillermina Barril ◽  
Ángel Nogueira ◽  
Graciela Alvarez ◽  
David Sapiencia ◽  
Natalia Andres ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Body Water ◽  
Cutoff Point ◽  
Hydration Status ◽  
Healthy Population ◽  
Nutritional Parameters ◽  
Multifrequency Bioimpedance ◽  
Total Body ◽  
Inflammation Parameters ◽  
Inflammation Score

Abstract Background and Aims Knowing the hydration status of CKD patients is one of the basic objectives in CKD patients considering the Ratio of EBW(TBW) as indicator of them. Aim Determine the cut-off point of the EBW/TBW ratio using Bioimpedance in patients with global CKD and divided into advanced CKD and hemodialysis (HD) as a hydration marker in relation to MIS scale (malnutrition inflammation score), cut-off point 5. Method We value 199 CKD patients by setting the EBW/TBW cut-off points using Inbody S10 multifrequency bioimpedance with global ROC curve and for advanced CKD (ACKD) and HD analyzing differences according to age ranges (<65,65,1-75 and >75 years) and differences in nutritional parameters (visceral proteins, MIS scale and body composition). Results We have evaluated 199 patients with ACKD, 143 male and 56 female, 74 in CKD xage72.27 ?11.98years and 125 in HD, xage 70.76 ?12.73 years. Overall EBW / TBW ratio: AUC 0.657, p0.006, cut-off point 0.3965 60% sensitivity, 64% specificity. Advanced CKD: AUC 0.648, p0.071, cutoff point 0.397, 64% sensitivity, 61% specificity. HD: AUC 0.706, p0.012, cutoff point 0.391, 71% sensitivity, 63% specificity. The results in relation to age strata and MIS with 5 as the cut-off point in the table. No greater hydration in men than in women overall. The nutrition-inflammation parameters according to the cut-off point are different: Advanced CKD: age 0.001, albumin 0.024, prealbumin 0.013, trasferrin 0.078, CRP 0.432. HD: albumin 0.014, prealbumin 0.001, transferrin 0.939, lymphocytes 0.030, CRP 0.342, age 0.000. Conclusion 1. We have found slightly higher cut-off points between ACKD and hemodialysis in the assessed sample. 2. The EBW / TBW ratio appears higher in patients > 65 years in both ACKD and HD, in contrast to what is observed in the healthy population. 3. A greater malnutrition appairs in a greater hyperhydration in HD and ACKD.

scholarly journals Adaptation and Validation of the Hydration Status Questionnaire in a Spanish Adolescent-Young Population: A Cross Sectional Study

Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 565 ◽  
Author(s):  
Ana Isabel Laja García ◽  
Maria de Lourdes Samaniego-Vaesken ◽  
Teresa Partearroyo ◽  
Gregorio Varela-Moreiras
Keyword(s):  
Specific Gravity ◽  
Water Intake ◽  
Total Body Water ◽  
Body Water ◽  
Urine Specific Gravity ◽  
Hydration Status ◽  
Young Population ◽  
Dietary Record ◽  
Adequate Hydration ◽  
Total Body

The achievement of adequate hydration status is essential for mental and physical performance and for health in general, especially in children and adolescents. Nevertheless, little is known about hydration status of this population, mainly due to the limited availability of research tools; thus, the objective of the current study was to adapt and validate our hydration status questionnaire in a Spanish adolescent-young population. The questionnaire was validated against important hydration markers: urine colour, urine specific gravity, haemoglobin, haematocrit and total body water and involved 128 subjects aged between 12–17 years. Water intake was also estimated through a three-day dietary record and physical activity was assessed through accelerometers. Participants completed the questionnaire twice. Water balance and water intake were correlated with urine specific gravity and with total body water content. Water intake obtained by the questionnaire was correlated with results from the three-day dietary record. The intraclass correlation coefficient indicated moderate concordance between both recordings and the Cronbach’s alpha revealed high consistency. The Bland and Altman method indicated that the limits of agreement were acceptable to reveal the reliability of the estimated measures. In conclusion, this is the first time that a questionnaire is valid and reliable to estimate hydration status of adolescent-young populations.

Effect of skin temperature on multifrequency bioelectrical impedance analysis

1996 ◽  
Vol 81 (2) ◽  
pp. 838-845 ◽  
Author(s):  
R. Gudivaka ◽  
D. Schoeller ◽  
R. F. Kushner
Keyword(s):  
Skin Temperature ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Skin Surface ◽  
Body Water ◽  
Heating And Cooling ◽  
Water Compartments ◽  
Multifrequency Bioimpedance ◽  
Measured Impedance ◽  
Total Body

This study assessed the effects of changes in skin temperature on multifrequency bioimpedance analysis (MF-BIA) and on the prediction of body water compartments. Skin temperature (baseline 29.3 +/- 2.1 degrees C) of six healthy adults was raised over 50 min to 35.8 +/- 0.6 degrees C, followed by cooling for 20 min to 26.9 +/- 1.3 degrees C, by using an external heating and cooling blanket. MF-BIA was measured at both distal (conventional) and proximal electrode placements. Both distal and proximal impedance varied inversely with a change in skin temperature across all frequencies (5–500 kHz). The change in proximal impedance per degree centigrade change in skin surface temperature was approximately 60% of distal impedance. The change in measured impedance at 50 kHz erroneously increased predicted total body water (TBW) by 2.6 +/- 0.9 liters (P < 0.001) and underpredicted fat mass by 3.3 +/- 1.3 kg (P < 0.0001). Computer modeling of the MF-BIA data indicated changes in predicted water compartments with temperature modifications; however, the ratio of extracellular water (ECW) to TBW did not significantly change (P < 0.4). This change in impedance was not due to a change in the movement of water of the ECW compartment and thus probably represents a change in cutaneous impedance of the skin. Controlled ambient and skin temperatures should be included in the standardization of BIA measurements. The error in predicted TBW is < 1% within an ambient temperature range of 22.3 to 27.7 degrees C (72.1–81.9 degrees F).

scholarly journals Skeletal Muscle Mass and Extracellular Water/Total Body Water Independently Predict Phase Angle Percentile in Young Men

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1169-1169
Author(s):  
Jacob Gray ◽  
Tay Kennedy
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Phase Angle ◽  
Total Body Water ◽  
Skeletal Muscle Mass ◽  
Body Water ◽  
Hydration Status ◽  
State University ◽  
Extracellular Water ◽  
Total Body

Abstract Objectives Phase angle, derived from bioelectrical impedance analysis (BIA), is used to describe both cellular and overall health. Many of the variables measured using BIA vary based on the hydration status of the individual. The ratio between extracellular water/total body water is commonly measured in BIA, and can be used as a measure of individual hydration. This pilot study explores the relationship between individual hydration status and phase angle and other BIA measurements. Methods Male college students (n = 57) from Oklahoma State University-Stillwater were recruited through an email messaging campaign. The participants answered an online Qualtrics demographic survey; height (±0.1 cm), blood pressure, and weight were taken. The Seca Medical Body Composition Analyzer mBCA 514 was used to conduct the BIA. Variable mean, standard deviations, and frequencies were calculated using SPSS version 25. Pearson correlation analysis and regression analysis were conducted. Significance was set at &lt;.05. Results Participants characteristics included: age (m = 21.7 ± 1.3 years), 54% BMI &lt;25, 39% blood pressure &lt;120/80, and 63% white/7% Native American. Mean % body fat was 20.28 ± 8.76, and skeletal muscle was 32.223 kg ± 4.432 and visceral fat was 2.01 liters ± 2.11.Phase angle percentile ranged from 1% to 99% (m = 62.0% ± 31.4) and extracellular water/total body water ratio (ECW/TBW) ranged from 35.7 to 41.6 (m = 39.32 ± 1.35). Phase angle percentile was positively correlated with skeletal muscle mass (r = 0.503, P = 0.000) and negatively correlated with ECW/TBW (r = −0.659, P = 0.000), but not with other BIA variables. These two variables significantly predicted phase angle percentile (r2 = 0.817, P = 0.000). The standardized β was −0.762 (P = 0.000) for ECW/TBW and 0.627 (P = 0.000) for skeletal muscle mass. Conclusions The association of ECW/TBW on phase angle percentile suggest further investigation of the impact of water on this indicator of health is warranted. An investigation with a method of modulating ECW/TBW would be a logical next step in understanding this relationship. Funding Sources Funding was provided by the Lew Wentz Foundation, and the Nutritional Sciences Department at Oklahoma State University.

scholarly journals Trajectories of Nutritional Parameters Before and After Prescribed Oral Nutritional Supplements: A Longitudinal Cohort Study of Patients With Chronic Kidney Disease Not Requiring Dialysis

2022 ◽  
Vol 9 ◽  
pp. 205435812110690
Author(s):  
Michelle M. Y. Wong ◽  
Yuyan Zheng ◽  
Dani Renouf ◽  
Zainab Sheriff ◽  
Adeera Levin
Keyword(s):  
Chronic Kidney Disease ◽  
Cluster Analysis ◽  
Cohort Study ◽  
Nutritional Supplements ◽  
Nutritional Supplement ◽  
Nutritional Parameters ◽  
Oral Nutritional Supplement ◽  
Oral Nutritional Supplements ◽  
Before And After ◽  
Inflammation Parameters

Background: The association between oral nutritional supplement use and nutritional parameters among patients with nondialysis chronic kidney disease (CKD-ND) with or at high risk of undernutrition/protein-energy wasting has not been previously studied. The definition of patient subgroups most likely to benefit from oral nutritional supplementation (ONS) is also an area where more research is needed. Objective: To assess nutritional parameter trajectories among patients with CKD-ND prescribed oral nutritional supplements in British Columbia, and to compare trajectories by nutritional phenotype. Design: Longitudinal cohort study, pre-post design. Setting: Multidisciplinary CKD clinics across British Columbia. Patients: A total of 3957 adult patients with CKD-ND, who entered multidisciplinary CKD clinics during 2010 to 2019, met criteria for oral nutritional supplement prescription based on dietitian assessment, and received ≥1 oral nutritional supplement prescription. Measurements: Longitudinal nutritional parameters, including body mass index (BMI), serum albumin, serum bicarbonate, serum phosphate, and neutrophil-to-lymphocyte ratio (NLR). Methods: Using linear mixed models, slopes for nutritional and inflammation parameters were assessed in the 2-year periods before and after the first oral nutritional supplement prescription. Hierarchical cluster analysis was applied to identify nutritional phenotypes using baseline data, and slope analysis was repeated by cluster. Results: In the pre-oral-nutritional-supplement period, declines in BMI (−0.87 kg/m2/year, 95% confidence interval [CI]: −0.99 to −0.75), albumin (−1.11 g/L/year, 95% CI: −1.27 to −0.95), and bicarbonate (−0.49 mmol/L/year; 95% CI: −0.59 to −0.39), and increases in NLR (+0.79/year; 95% CI: 0.60 to 0.98) and phosphate (+0.05 mmol/L/year; 95% CI: 0.04 to 0.06) were observed. Following oral nutritional supplement prescription, there were statistically significant increases in BMI slope (+0.91 kg/m2/year, P < .0001), albumin slope (+0.82 g/L/year, P < .0001), and phosphate slope (+0.02 mmol/L/year, P = .005), as well as a decline in NLR slope of −0.55/year ( P < .0001). There was no significant change in bicarbonate slope. Cluster analysis identified 5 distinct phenotypes. The cluster with the highest mean baseline NLR and lowest mean BMI demonstrated the greatest number of improvements in nutritional parameter slopes in the post-oral-nutritional-supplement period. Limitations: Possibility of residual confounding. Data on dietary intake, muscle mass, and nutritional scoring systems were not available in the registry. Conclusions: Among patients with CKD-ND prescribed oral nutritional supplements, there were improvements in nutrition/inflammation parameters over time following the first ONS prescription. The heterogeneity in response to ONS by cluster subgroup suggests an individualized approach to nutritional management may be beneficial.

scholarly journals Correlation Between Predialysis Systolic Blood Pressure and Predialysis Hydration Status in Hemodialysis Patients

2018 ◽  
Vol 3 (4) ◽  
pp. 1025-1030
Author(s):  
Magdalena Castro ◽  
Rodrigo Orozco ◽  
Pedro Figueroa ◽  
Cristina Hertz ◽  
Victoria Aspillaga
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Systolic Blood Pressure ◽  
Total Body Water ◽  
Pearson Correlation ◽  
Body Water ◽  
Hydration Status ◽  
Dialysis Session ◽  
Ultrafiltration Rate ◽  
Total Body

One of the goals of hemodialysis is to maintain normal hydration status in ESRD patients. Pre hemodialysis systolic blood pressure is usually used as a clinical parameter of hydration status and to set ultrafiltration rate before Hd. It is unclear how much pre-Hd SBP correlated with hydration status. The aim was to determine correlation between pre-Hd SBP and hydration status before Hd. An observational correlation study was performed in two dialysis centers in Santiago, Chile, from January-June, 2011. Adult patients in Hd for at least three months, who gave their informed consent were included. Patients with pacemaker, amputee, hospitalized and metallic prostheses were excluded. Total-body water and overhydrated were assessed with bioimpedance spectroscopy before the first and third dialysis session of the week. Pre-Hd SBP, pre-Hd body weight, pre-Hd TBW and pre-Hd OH, were analyzed using Pearson correlation and linear regression model. 96 measurements were assessed, 52 % were male with median age 59.5 years. The correlation between pre-Hd SBP and pre-Hd overhydration was r=0.33, and total body water r=0.15, with a predicted value, R2=0.10 and R2 =0.14 respectively. Pre-Hd SBP had low correlation with pre-Hd hydration status and by itself, is not a reliable parameter to set ultrafiltration rate before Hd. Nevertheless Pre-Hd body weight predicted in 70 % the pre-Hd TBW.

scholarly journals Effect of a single dose of mannitol on hydration status and electrolyte concentrations in patients with tick-borne encephalitis

2018 ◽  
Vol 46 (12) ◽  
pp. 5083-5089 ◽  
Author(s):  
Piotr Czupryna ◽  
Anna Moniuszko-Malinowska ◽  
Sambor Grygorczuk ◽  
Sławomir Pancewicz ◽  
Justyna Dunaj ◽  
...  
Keyword(s):  
Single Dose ◽  
Body Water ◽  
Water Volume ◽  
Hydration Status ◽  
Electrolyte Balance ◽  
Creatinine Concentration ◽  
Tick Borne Encephalitis ◽  
Before And After ◽  
Fluid Supplementation ◽  
Total Body

Objective This study was performed to assess the effect of a single dose of 15% mannitol on the hydration status and electrolyte balance in patients with tick-borne encephalitis (TBE). Methods Forty-one patients with TBE were treated with 0.25 g/kg of 15% mannitol. The electrolyte concentrations (Na, K, and Cl), creatinine concentration, and hydration status were measured before and after mannitol infusion. Results After mannitol administration, 7 patients had hyponatremia, 3 had hypokalemia, 1 had hyperkalemia, and 17 had hypochloremia. The total body water volume (TBW) changed by 0.44% ± 0.55%, the external body water volume (EBW) changed by 0.12% ± 0.15%, and the internal body water volume (IBW) changed by 0.19% ± 0.40%. The mean ECW/ICW ratio was 0.7694 ± 0.07 before treatment and 0.7699 ± 0.07 after treatment. Age was correlated with the TBW change in men (R = 0.42, p < 0.05) and with the potassium change in women (R = 0.66, p < 0.05). Conclusions Patients with TBE should receive mannitol two to four times daily depending on the clinical manifestation. Administration of a single dose of mannitol (0.25 g/kg) requires at least 300 mL of fluid supplementation. Bioimpedance might be useful for individual evaluation of dehydration. Additionally, patients require monitoring for potential hyponatremia. Older men may be more prone to dehydration after receiving mannitol.

Total body water and its compartments are not affected by ingesting a moderate dose of caffeine in healthy young adult males

2013 ◽  
Vol 38 (6) ◽  
pp. 626-632 ◽  
Author(s):  
Analiza M. Silva ◽  
Pedro B. Júdice ◽  
Catarina N. Matias ◽  
Diana A. Santos ◽  
João P. Magalhães ◽  
...  
Keyword(s):  
Body Composition ◽  
Repeated Measures ◽  
Total Body Water ◽  
Deuterium Oxide ◽  
Body Water ◽  
Fluid Distribution ◽  
Hydration Status ◽  
Moderate Dose ◽  
Water Ingestion ◽  
Total Body

Acute and chronic caffeine intakes have no impact on hydration status (R.J. Maughan and J. Griffin, J. Hum. Nutr. Diet. 16(6): 411–420, 2003), although no research has been conducted to analyze the effects using dilution techniques on total-body water (TBW) and its compartments. Therefore, the aim of this study was to investigate the effects of a moderate dose of caffeine on TBW, extracellular water (ECW), and intracellular water (ICW) during a 4-day period in active males. Thirty men, nonsmokers and low caffeine users (<100 mg·day−1), aged 20–39 years, participated in this double-blind, randomized, crossover trial (ClinicalTrials.gov: No. NCT01477294). The study included 2 conditions (5 mg·kg−1·day−1 of caffeine and placebo (malt-dextrin)) of 4 days each, with a 3-day washout period. TBW and ECW were assessed by deuterium oxide and sodium bromide dilution, respectively, whereas ICW was calculated as TBW minus ECW. Body composition was assessed by dual-energy X-ray absorptiometry. Physical activity (PA) was assessed by accelerometry and water intake was assessed by dietary records. Repeated-measures analysis of variance (ANOVA) was used to test main effects. No changes in TBW, ECW, or ICW and no interaction between the randomly assigned order of treatment and time were observed (p > 0.05). TBW, ECW, and ICW were unrelated to fat-free mass, water ingestion, and PA (p > 0.05). These findings indicate that a moderate caffeine dose, equivalent to approximately 5 espresso cups of coffee or 7 servings of tea, does not alter TBW and fluid distribution in healthy men, regardless of body composition, PA, or daily water ingestion.

scholarly journals Validity of Bioimpedance Spectroscopy in the Assessment of Total Body Water and Body Composition in Wrestlers and Untrained Subjects

2020 ◽  
Vol 17 (24) ◽  
pp. 9433
Author(s):  
Keisuke Shiose ◽  
Emi Kondo ◽  
Rie Takae ◽  
Hiroyuki Sagayama ◽  
Keiko Motonaga ◽  
...  
Keyword(s):  
Body Composition ◽  
Total Body Water ◽  
Compartment Model ◽  
Body Water ◽  
Fat Free Mass ◽  
Hydration Status ◽  
Dilution Method ◽  
Bioimpedance Spectroscopy ◽  
Japanese Male ◽  
Total Body

Bioimpedance spectroscopy (BIS) is an easy tool to assess hydration status and body composition. However, its validity in athletes remains controversial. We investigated the validity of BIS on total body water (TBW) and body composition estimation in Japanese wrestlers and untrained subjects. TBW of 49 young Japanese male subjects (31 untrained, 18 wrestlers) were assessed using the deuterium dilution method (DDM) and BIS. De Lorenzo’s and Moissl’s equations were employed in BIS for TBW estimation. To evaluate body composition, Siri’s 3-compartment model and published TBW/fat-free mass (FFM) ratio were applied in DDM and BIS, respectively. In untrained subjects, DDM and BIS with de Lorenzo’s equation showed consistent TBW estimates, whereas BIS with Moissl’s equation overestimated TBW (p < 0.001 vs. DDM). DDM and BIS with de Lorenzo’s equation estimated FFM and percent of fat mass consistently, whereas BIS with Moissl’s equation over-estimated and under-estimated them (p < 0.001 vs. DDM). In wrestlers, BIS with de Lorenzo’s and Moissl’s equations assessed TBW similarly with DDM. However, the Bland–Altman analysis revealed a proportional bias for TBW in BIS with de Lorenzo’s equation (r = 0.735, p < 0.001). Body composition assessed with BIS using both equations and DDM were not different. In conclusion, BIS with de Lorenzo’s equation accurately estimates the TBW and body composition in untrained subjects, whereas BIS with Moissl’s equation is more valid in wrestlers. Our results demonstrated the usefulness of BIS for assessing TBW and body composition in Japanese male wrestlers.

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