scholarly journals MO038EFFECTIVENESS OF CORTICOSTEROID THERAPY FOR PATIENTS WITH CKD G3-4 IGA NEPHROPATHY: A MULTICENTER, LARGE SCALE, LONG-TERM OBSERVATION COHORT STUDY

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii58-iii59
Author(s):  
Ryouya Tsunoda ◽  
Joichi Usui ◽  
Junichi Hoshino ◽  
Takayuki Fujii ◽  
Satoshi Suzuki ◽  
...  
Keyword(s):  
Cohort Study ◽  
Iga Nephropathy ◽  
Corticosteroid Therapy ◽  
Large Scale ◽  
Long Term Observation

scholarly journals Posterior Uveal Effusion after Cataract Surgery

2021 ◽  
pp. 62-67
Author(s):  
Annegret Abaza ◽  
Özlem Dikmetas ◽  
Irmingard Neuhann ◽  
Faik Gelisken
Keyword(s):  
Cataract Surgery ◽  
Corticosteroid Therapy ◽  
Anterior Segment ◽  
Subretinal Fluid ◽  
Posterior Pole ◽  
Functional Improvement ◽  
Long Term Observation ◽  
The Right ◽  
Uveal Effusion

We report a case of posterior uveal effusion (UE) with a long-term follow-up that has occurred following cataract surgery. A 64-year-old woman presented with diminished vision of the right eye (RE) 3 weeks after an uneventful phacoemulsification and intraocular lens implantation. Complete ophthalmic examination including fluorescein angiography (FA), indocyanine green angiography (ICGA), echography and optical coherence tomography (OCT) were performed. Best corrected visual acuity (BCVA) of the RE was 20/50. Anterior segment and intraocular pressure were unremarkable. OCT revealed prominent folds of the choroid and retina, subretinal fluid and darkening of the choroid with reduced visibility of the choroidal vessels and the scleral border. The left eye (LE) was unremarkable. BCVA of the LE was: 20/20. After topical anti-inflammatory and systemic corticosteroid therapy for 5 months, no morphological change of the macula was seen. The patient was observed without any treatment. Forty-three months after the cataract surgery and 38 months after cessation of the corticosteroid therapy, OCT revealed a normal macular morphology and the BCVA improved to 20/25. Even though rare, UE at the posterior pole may occur after modern cataract surgery. OCT examination is a reliable tool in monitoring the macular morphology. Since morphological and functional improvement can be seen in long-term, observation may be considered for some cases of posterior UE with resistance to the therapy.

Clinicopathological features and the prognosis of IgA nephropathy in Japanese children on long-term observation

2005 ◽  
Vol 64 (09) ◽  
pp. 171-179 ◽  
Author(s):  
R. Nozawa ◽  
J. Suzuki ◽  
A. Takahashi ◽  
M. Isome ◽  
Y. Kawasaki ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Clinicopathological Features ◽  
Japanese Children ◽  
Long Term Observation

scholarly journals The long-term outcomes in adolescent and young adult patients with colorectal cancer -A multicenter large-scale cohort study

2020 ◽  
Vol 11 (11) ◽  
pp. 3180-3185
Author(s):  
Yujiro Nakayama ◽  
Hiroshi Kobayashi ◽  
Hidetaka Kawamura ◽  
Rie Matsunaga ◽  
Yukitoshi Todate ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cohort Study ◽  
Young Adult ◽  
Large Scale ◽  
Adult Patients ◽  
Adolescent And Young Adult ◽  
Long Term Outcomes

scholarly journals Association Between Hormone Replacement Therapy and Development of Endometrial Cancer: Results From a Prospective US Cohort Study

2022 ◽  
Vol 8 ◽  
Author(s):  
Ying Liang ◽  
Haoyan Jiao ◽  
Lingbo Qu ◽  
Hao Liu
Keyword(s):  
Endometrial Cancer ◽  
Cohort Study ◽  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Large Scale ◽  
Proportional Hazards ◽  
Hormone Replacement ◽  
Cox Proportional Hazards

Although hormone replacement therapy (HRT) use is associated with elevated endometrial cancer(EC) risk, little evidence assesses potential effect-modifiers on HRT-related EC in a long-term follow-up. In this large-scale longitudinal cohort study, we tried to evaluate the association between different HRT types/methods use and risk of EC, and reveal this risk within different body mass index (BMI) groups. In whole cohort, 677 EC occurred during mean 11.6 years follow-up. Cox proportional hazards regression was used to estimate multivariable-adjusted hazards ratios (HRs) and 95% confidence intervals (CIs) with HRT status (never, former, or current) for risk of EC incidence. Current HRT use was not significantly associated with EC risk (HR for current vs. never HRT use: 1.13; 95% CI: 0.92, 1.38) in the whole cohort, but presented a dose-response effect on increased EC risk (HR for >10-year use vs. never HRT use: 1.73; 95% CI: 1.35, 2.21). Moreover, EC risk differed in distinct regimens or subsets (all Pinteraction < 0.05). Estrogen-only use was associated with elevated EC risk (HR for current vs. never HRT use: 1.51; 95% CI: 1.12, 2.04), but women with high BMI (> 30 kg/m2) who currently use estrogen-only harbored decreased EC risk (HR: 0.56; 95% CI: 0.38, 0.82) compared to counterparts without HRT use. Estrogen-only use is associated with increased EC risk, and precise monitoring of EC development for postmenopausal women with long-term HRT use are urgently needed. BMI could serve as an important surrogate to assess this risk.

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