P14.22 Quality indicators in neuro-oncology: modified Delphi process for the development of a quality indicator set for assessment of glioma care

2021 ◽  
Vol 23 (Supplement_2) ◽  
pp. ii42-ii42
Author(s):  
D J Vanhauwaert ◽  
H Pinson ◽  
H De Schutter ◽  
E Van Eycken ◽  
S De Vleeschouwer ◽  
...  

Abstract BACKGROUND Quality Indicators (QIs) are important tools to assess the quality and variability of oncological care. However, their application in neuro-oncology is limited. The objective of this study was to develop a set of QIs for glioma, covering process and outcome indicators. METHODS First a systematic literature search was performed in peer-reviewed papers and grey literature to identify existing QIs in neuro-oncology and guidelines or recommendations that could be translated into new QIs. The PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) checklist and flow diagram were taken into account. The search strategy focused on diagnostics, treatment, follow-up and survival. For each (set of similar) recommendation(s) a QI was created that could easily be translated into a measurable proportion. Concordant QIs were rationalized to further reduce redundancy. Secondly a two round Delphi survey was organized amongst a multidisciplinary expert panel that was asked to score relevance for all proposed QIs. The panel consisted of neurosurgeons(4), radiation(3) and medical(3) oncologists, pathologists(3), radiologists(2), neurologists(1), nuclear medicine physicians(2) from university and non-university centers, and representatives of the Belgian Cancer Registry. RESULTS The conducted literature search in PubMed and Embase yielded 2392 abstracts. After screening and duplicate removal, 221 full text articles were assessed of which 79 were retained. In addition 28 references from the Grey literature were added. In total 240 recommendations and 30 QIs could be identified in this way. After translation of these recommendations into a measurable proportion, merging with the QIs found as such in the literature and rationalization, 148 QIs were presented to the expert panel. In the Delphi survey 15 of the 19 (79%) invited experts responded and eventually consensus was reached on 46 QIs that were considered relevant for the assessment of 6 different domains of neuro-oncological care: diagnosis and imaging (10), surgery (4), pathology (6), radio/chemotherapy (14), recurrence (5) and supportive treatment (7). CONCLUSION A set of 46 QIs grouped in 6 categories to assess the quality of care of glioma patients was developed. These QI’s are readily applicable dependent on the availability of population-based health care data

2021 ◽  
Author(s):  
Paul Flynn ◽  
Sara Gartland ◽  
Joe Cullen ◽  
Maria Ana Carneiro ◽  
Jose de Sousa Fialho ◽  
...  

Abstract BackgroundThere is a clear and pressing need to understand the barriers to technology user experience, particularly in relation to people with cognitive disabilities. The COVID-19 pandemic and subsequent expansion of digital technologies associated with education, wellness and employment only makes the need to understand how people with cognitive disabilities interact with such technologies, within the naturalistic context of their lifeworld, increasingly urgent. Therefore a necessary first step is to develop a baseline understanding of the current state of web accessibility for people with cognitive disabilities. Thus, the purpose of this review is to conduct baseline research to understand the factors and processes that inhibit access to online content and services for people with cognitive impairments.MethodsThis systematic, rapid evidence assessment, review will employ a search strategy using defined terms within agreed search strings in the following databases: Web of Science, SCOPUS, EBSCOhost, ERIC and ProQuest. Internet searching through Google Scholar will be carried out as well as forward and backward tracking of citations from studies that are included in the review. All results, screening process results will be documented in tabular form and communicated in a PRISMA flow diagram. In addition, the research team consider it necessary to carry out a grey literature search due to the nature of the work being investigated. The expertise within the research team indicated that many programmes that support people with cognitive impairments do not formally report their work through academic dissemination pathways. Consequently it is intended that a grey literature search will be carried out to supplement that findings of study. In contrast to the focus on studies published in English for peer review returns, the grey literature search will actively seek out returns across all languages of the European Union.DiscussionThis rapid review protocol will focus on citizens ages 9 and up who live with cognitive impairment and establish a baseline for best practice in supporting web accessibility for people with cognitive impairments. It will achieve this by providing a time limited state-of-the-art evidence report, specific to the challenges people with cognitive impairment, that will help those involved in policy development, policy response initiatives and localised activity. It is intended that, depending on the outcome of the review process, additional opportunities for innovation and/or research may be communicated to relevant stakeholders and policy makers.Systematic Review RegistrationThis protocol has been submitted to the International Prospective Register for Systematic Reviews - PROSPERO, and is currently under review. Reference No. 269245.


2019 ◽  
Vol 70 (6) ◽  
pp. 1075-1082 ◽  
Author(s):  
Marvin A H Berrevoets ◽  
Jaap ten Oever ◽  
Anke J M Oerlemans ◽  
Bart Jan Kullberg ◽  
Marlies E Hulscher ◽  
...  

Abstract Background Our aim in this study was to develop quality indicators (QIs) for outpatient parenteral antimicrobial therapy (OPAT) care that can be used as metrics for quality assessment and improvement. Methods A RAND-modified Delphi procedure was used to develop a set of QIs. Recommendations on appropriate OPAT care in adults were retrieved from the literature using a systematic review and translated into potential QIs. These QIs were appraised and prioritized by a multidisciplinary panel of international OPAT experts in 2 questionnaire rounds combined with a meeting between rounds. Results The procedure resulted in 33 OPAT-specific recommendations. The following QIs that describe recommended OPAT care were prioritized by the expert panel: the presence of a structured OPAT program, a formal OPAT care team, a policy on patient selection criteria, and a treatment and monitoring plan; assessment for OPAT should be performed by the OPAT team; patients and family should be informed about OPAT; there should be a mechanism in place for urgent discussion and review of emergent clinical problems, and a system in place for rapid communication; laboratory results should be delivered to physicians within 24 hours; and the OPAT team should document clinical response to antimicrobial management, document adverse events, and monitor QIs for OPAT care and make these data available. Conclusions We systematically developed a set of 33 QIs for optimal OPAT care, of which 12 were prioritized by the expert panel. These QIs can be used to assess and improve the quality of care provided by OPAT teams.


Author(s):  
Ashley M. Williams ◽  
Jamaal Young

The purpose of this systematic review was to characterize the implementation of reliability generalization meta-analytic (RGM) practices within mathematics education-related empirical research. RGM studies are used to investigate and generalize the reliability of a measure across various studies. An exhaustive literature search was conducted to locate studies related to mathematics education, including RGM studies of psychological tests. The literature search included articles as well as grey literature (e.g., conference proceedings, dissertations, theses). Of the 27 RGM studies examined, five were on scales that related to mathematics education research, five were on scales related to motivation and/or learning, four related to self-esteem, self-concept, and/or self-efficacy, six related to perceptions, well-being, and/or anxiety, and seven related to personality or behavior. Of the mathematics education-related RGM studies, 85.5% (N=9,184) of the articles examined across studies had no mention of reliability or fell into the convention of citing previously reported reliabilities. Increasing awareness of RGM studies could lead to an increase in RGM studies conducted on mathematics education research scales, leading to increased understanding of mathematics education scales. This paper contributes to the literature on the practical and empirical importance of RGM for mathematics and STEM education praxis. 


2014 ◽  
Vol 24 (3) ◽  
pp. 355-368 ◽  
Author(s):  
Rosa E. Raudales ◽  
Tracy A. Irani ◽  
Charles R. Hall ◽  
Paul R. Fisher

A wide range of water-treatment technologies is used to control waterborne microbial problems in greenhouse and nursery irrigation. An online modified Delphi survey was carried out to identify the perceived key attributes that growers should consider when selecting among water-treatment technologies and to characterize a list of 14 technologies based on those same attributes. The expert panel consisted of ornamental plant growers (n = 43), water-treatment industry suppliers (n = 28), and research and extension faculty (n = 34). The survey was delivered to the expert panel in two rounds. Response rate was 59% and 60% for the first and second rounds, respectively. Growers identified control of plant disease, algae, and biofilm as primary reasons for adopting technologies, whereas mandatory regulation was not a major reason for adoption. All 23 attributes (related to cost, system size, control of microorganisms, chemistry, ease of use, and regulation) were perceived to be important when selecting between water-treatment technologies. Injectable sanitizing chemicals such as chlorination were considered to have low capital cost, unlike technologies that required installation of more complex equipment, such as heat treatment, hydrogen peroxide, ozone, reverse osmosis, or ultraviolet radiation. Filtration (excluding membrane filtration) was the only technology not perceived to be effective to control microorganisms. Filtration and copper were not considered effective to control human food-safety pathogens. Ozone was rated the highest as a technology that removes or oxidizes agrochemicals. Chemical water treatments, as opposed to physical water treatments, were perceived to be sensitive to water quality parameters and to have residual effect through the irrigation. Chlorine gas was perceived to be the only technology for which regulatory permission would be an obstacle. All technologies were perceived to be effective in water with low electrical conductivity (EC) or in solutions containing water-soluble fertilizers. This survey documents perceived attributes of water-treatment technologies, which are most useful where experimental data are not yet available. Research and outreach needs were highlighted by cases where perceived attributes differed from available experimental data or where there was a lack of consensus between experts.


BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e028699
Author(s):  
Birgitta Ljungbeck ◽  
Katarina Sjogren Forss ◽  
Hafrún Finnbogadóttir ◽  
Elisabeth Carlson

IntroductionGlobally, nurse practitioner (NP) has become an important nursing role in the pursuit of a more efficient healthcare, possessing the necessary expert skills to work as autonomous practitioners. Nevertheless, there are barriers in the implementation of this role. One barrier concerns the different levels of education required for NPs. Previous studies demonstrate the importance of acting for a uniform international education. The aim of the scoping review was to compile research about education to become an NP, focusing on the content of curricula and learning objectives.Methods and analysisThe six-stage methodological framework by Arksey and O’Malley will guide the scoping review through the following stages: identifying the research questions; identifying relevant studies; study selection; charting the data; collating, summarising and reporting the results; and consultation. The research questions are as follows: What is the content of curricula in NP programmes? What are the learning objectives in NP programmes? The literature searches will be conducted between March and June 2019 in the following databases: PubMed, CINAHL and ERIC, followed by hand searching reference lists of key studies. Grey literature will be searched in Google Scholar, Libsearch, existing networks and relevant organisations. Two researchers will screen titles and abstracts. Included full-text articles will be screened by three researchers and assessed for their methodological quality by the use of the Critical Appraisal Skills Programme. The PreferredReporting Items for Systematic Reviews and Meta-Analyses flow diagram will be used to demonstrate included and excluded articles. The findings will be presented through a numerical summary of the included articles, followed by a thematic analysis.Ethics and disseminationResearch ethics approval is not required for a scoping review. The scoping review will be submitted to a peer-reviewed journal. Additionally, the findings will be disseminated to stakeholders representing political, educational, professional and union organisations through a Delphi study as part of the consultation stage of the Arksey and O’Malleys framework.


Author(s):  
Lorraine C. Toews

Objective: Complete, accurate reporting of systematic reviews facilitates assessment of how well reviews have been conducted. The primary objective of this study was to examine compliance of systematic reviews in veterinary journals with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines for literature search reporting and to examine the completeness, bias, and reproducibility of the searches in these reviews from what was reported. The second objective was to examine reporting of the credentials and contributions of those involved in the search process.Methods: A sample of systematic reviews or meta-analyses published in veterinary journals between 2011 and 2015 was obtained by searching PubMed. Reporting in the full text of each review was checked against certain PRISMA checklist items.Results: Over one-third of reviews (37%) did not search the CAB Abstracts database, and 9% of reviews searched only 1 database. Over two-thirds of reviews (65%) did not report any search for grey literature or stated they excluded grey literature. The majority of reviews (95%) did not report a reproducible search strategy.Conclusions: Most reviews had significant deficiencies in reporting the search process that raise questions about how these searches were conducted and ultimately cast serious doubts on the validity and reliability of reviews based on a potentially biased and incomplete body of literature. These deficiencies also highlight the need for veterinary journal editors and publishers to be more rigorous in requiring adherence to PRISMA guidelines and to encourage veterinary researchers to include librarians or information specialists on systematic review teams to improve the quality and reporting of searches.


2019 ◽  
Vol 37 (14) ◽  
pp. 1228-1263 ◽  
Author(s):  
Joseph Mikhael ◽  
Nofisat Ismaila ◽  
Matthew C. Cheung ◽  
Caitlin Costello ◽  
Madhav V. Dhodapkar ◽  
...  

PURPOSE To provide evidence-based recommendations on the treatment of multiple myeloma to practicing physicians and others. METHODS ASCO and Cancer Care Ontario convened an Expert Panel of medical oncology, surgery, radiation oncology, and advocacy experts to conduct a literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and some phase II studies published from 2005 through 2018. Outcomes of interest included survival, progression-free survival, response rate, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. RESULTS The literature search identified 124 relevant studies to inform the evidence base for this guideline. RECOMMENDATIONS Evidence-based recommendations were developed for patients with multiple myeloma who are transplantation eligible and those who are ineligible and for patients with relapsed or refractory disease.


2018 ◽  
Vol 36 (13) ◽  
pp. 1343-1373 ◽  
Author(s):  
Hedy L. Kindler ◽  
Nofisat Ismaila ◽  
Samuel G. Armato ◽  
Raphael Bueno ◽  
Mary Hesdorffer ◽  
...  

Purpose To provide evidence-based recommendations to practicing physicians and others on the management of malignant pleural mesothelioma. Methods ASCO convened an Expert Panel of medical oncology, thoracic surgery, radiation oncology, pulmonary, pathology, imaging, and advocacy experts to conduct a literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and prospective and retrospective comparative observational studies published from 1990 through 2017. Outcomes of interest included survival, disease-free or recurrence-free survival, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. Results The literature search identified 222 relevant studies to inform the evidence base for this guideline. Recommendations Evidence-based recommendations were developed for diagnosis, staging, chemotherapy, surgical cytoreduction, radiation therapy, and multimodality therapy in patients with malignant pleural mesothelioma. Additional information is available at www.asco.org/thoracic-cancer-guidelines and www.asco.org/guidelineswiki .


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