scholarly journals 851Reducing Bio-burden and Healthcare Associated Infection Risk Among Hospitalized Patients: Adoptability of Chlorhexidine Gluconate Bathing Among Non-ICU Patients

2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S244-S244
Author(s):  
Shruti K. Gohil ◽  
Brian Murray ◽  
Edward Kim ◽  
Justin Chang ◽  
Susan S. Huang
Author(s):  
Aaron C Miller ◽  
Daniel K Sewell ◽  
Alberto M Segre ◽  
Sriram V Pemmaraju ◽  
Philip M Polgreen ◽  
...  

Abstract Purpose Clostridioides difficile infections (CDIs) are a common healthcare-associated infection and often used as indicators of hospital safety or quality. However, healthcare exposures occurring prior to hospitalization may increase risk for CDI. We conduct a case-control study comparing hospitalized patients with and without CDI to determine if healthcare exposures prior to hospitalization (i.e., clinic visits, antibiotics, family members with CDI) were associated with increased risk for hospital onset CDI, and how risk varied with time between exposure and hospitalization. Methods Records were collected from a large insurance-claims database from 2001-2017 for hospitalized adult patients. Prior healthcare exposures were identified using inpatient, outpatient, emergency department, and prescription drug claims; results were compared between various CDI case definitions. Results Hospitalized patients with CDI had significantly more frequent healthcare exposures prior to admission. Healthcare visits, antibiotics and family exposures were associated with greater likelihood of CDI during hospitalization. The degree of association diminished with time between exposure and hospitalization. Results were consistent across CDI case definitions. Conclusions Many different prior healthcare exposures appear to increase risk for CDI presenting during hospitalization. Moreover, patients with CDI typically have multiple exposures prior to admission, confounding the ability to attribute cases to a particular stay.


2019 ◽  
Vol 2 (1) ◽  
pp. 8-12
Author(s):  
Maham Zahid ◽  
Aysha Siddiqa ◽  
Rehna Javaid ◽  
Hafsa Khalil ◽  
Farrah Pervaiz

Objective: Hospitalized patients can pick infections from healthcare facilities which may lead to extended hospital stay, increased morbidity and mortality of hospitalized patients and economic burden on health care. Active surveillance of HAIs that is continuous and prospective in nature has been accepted as a gold standard approach in preventing and controlling healthcare associated infections. To estimate the prevalence HAIs and their types in a tertiary care cardiac center and to identify associated risk factors. Methodology: Nine prospective point prevalence surveys were conducted on three separate days in three consecutive weeks for three months. A data collectors team comprising of two research officers and an infection control nurse, visited the enrolled patients and patient’s history, demographics, physical examination, laboratory findings and other details were reviewed from patient files and recorded on study questionnaire. Results: A total of 559 patients were enrolled in the study. The prevalence of HAIs was 6.4%, which means 36 HAIs were identified in 559 patients. Univariate analysis showed a significant association between HAI and being in ICU/CCU ward (OR 3.4, 95% CI 1.5-7.4) longer duration of hospital stay (OR 3.0, 95% CI 1.5-6.0, P=0.001), exposure to urinary catheter, use of antimicrobials (OR 2.8, 95% CI 1.3-6.1, P=0.006), and diabetes (OR 2.5, 95% CI 1.2-5.2, P=0.008). Conclusion: Healthcare associated infection is a major public health problem and rate of HAIs in the selected centers was found to be 6.4%. Present survey provided baseline evidence for further surveillance and multifaceted infection.


2016 ◽  
Vol 37 (10) ◽  
pp. 1234-1242 ◽  
Author(s):  
Daniel A. Caroff ◽  
Paul M. Szumita ◽  
Michael Klompas

BACKGROUNDHealthcare-associated infections (HAIs) cause significant morbidity in critically ill patients. An underappreciated but potentially modifiable risk factor for infection is sedation strategy. Recent trials suggest that choice of sedative agent, depth of sedation, and sedative management can influence HAI risk in mechanically ventilated patients.OBJECTIVETo better characterize the relationships between sedation strategies and infection.METHODSSystematic literature review.RESULTSWe found 500 articles and accepted 70 for review. The 3 most common sedatives for mechanically ventilated patients (benzodiazepines, propofol, and dexmedetomidine) have different pharmacologic and immunomodulatory effects that may impact infection risk. Clinical data are limited but retrospective observational series have found associations between sedative use and pneumonia whereas prospective studies of sedative interruptions have reported possible decreases in bloodstream infections, pneumonia, and ventilator-associated events.CONCLUSIONInfection rates appear to be highest with benzodiazepines, intermediate with propofol, and lowest with dexmedetomidine. More data are needed but studies thus far suggest that a better understanding of sedation practices and infection risk may help hospital epidemiologists and critical care practitioners find new ways to mitigate infection risk in critically ill patients.Infect Control Hosp Epidemiol 2016;1–9


Author(s):  
Alba Luz Rodríguez‐Acelas ◽  
Miriam Abreu Almeida ◽  
Manoela Schmarczek Figueiredo ◽  
Vanessa Monteiro Mantovani ◽  
Rita Mattiello ◽  
...  

Author(s):  
Gene H Burke ◽  
Jacqueline P Butler

The aim of this study was to evaluate the impact of copper-impregnated composite hard surfaces, bed linens and patient gowns on healthcare-associated infections (HAIs). We took in account potentially confounding factors of new construction and Det Norse Veritas Managing Infection Risk (DNV MIR) certification to mitigate risk of HAIs, multi drug resistant organisms (MDRO) and Clostridium difficile HAIs. The study was conducted in the acute care units from three hospitals within a regional healthcare system and these were assessed retrospectively. Facility 1 and Facility 2 shared the circumstance of new construction. Facility 1 and Facility 3 shared the processes of DNV-MIR. Only Facility 1 undertook the intervention of copper-impregnated hard surfaces, bed linens and patient gowns. We compared infection rates (IR) following their normalization per 10,000 patient hospitalization days before and after complete implementation of copper-impregnated composite hard surfaces, bed linens and patient gowns. Facility 1 had a 28% reduction in total C. difficile and MDRO IR, while Facilities 2 and 3 had 103% and 48% increases in total IR respectively. Although the rate changes per facility were not statistically significantly changed from baseline (p>0.05), there was consistent divergence between the IR at the copper enabled facility and the others. As this divergence occurred when other pertinent factors were constant between them, including new construction and new processes for mitigation of infection risks, these outcomes support the contention that copper-impregnated linens and composite hard surfaces were shown to reduce HAI rates.


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