scholarly journals 2524. Prevalence and Associated Factors of Seroprotection Against Japanese Encephalitis Virus Among HIV-Infected Thai Adolescents Stable on Combination Antiretroviral Treatment

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S877-S878
Author(s):  
Tavitiya Sudjaritruk ◽  
Suparat Kanjanavanit ◽  
Chanidapa Prasarakee ◽  
Saowalak Sarachai ◽  
Wanvisa Taweehorm ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Japanese Encephalitis ◽  
Logistic Regression Analysis ◽  
Neutralizing Antibodies ◽  
Associated Factors ◽  
Antiretroviral Treatment ◽  
Geometric Mean ◽  
Immunosuppressive Agents ◽  
Multivariable Logistic Regression Analysis

Abstract Background To determine the prevalence and associated factors of seroprotection against Japanese encephalitis (JE) virus among HIV-infected adolescents stable on combination antiretroviral treatment (cART). Methods A multicenter seroprevalence study was conducted in Thailand. Perinatally HIV-infected adolescents who aged 11–25 years, had previous evidence of severely immune suppression (CD4 < 15% or < 200 cells/mm3), were currently stable on cART (CD4 > 350 cells/mm3 for > 6 months or CD4 > 200 cells/mm3 with viral suppression [VS; plasma HIV RNA < 50 copies/mL] for > 12 months), and had completed a 3- or 4-dose series of mouse brain-derived inactivated JE vaccine (MBDV) during childhood were enrolled. Adolescents who had clinically or serologically confirmed recent JE virus infections, or received immunosuppressive agents or blood components within 6 months were excluded. Plaque reduction neutralization (PRNT50) assay was conducted to assess neutralizing antibodies to JE virus, and titers of ≥ 10 were considered seroprotective. Logistic regression analysis was performed to identify associated factors of JE seroprotection. Results Of 98 eligible adolescents, 54% were female, a median age was 19 years, and 11% were overweight. Ninety-five percent and 5% of adolescents received 3 and 4 doses of MBDV during childhood, respectively. A median duration since the last dose of MBDV was 16 years. At enrollment, 71% were on NNRTI-based cART regimens, a median cART duration was 13 years. A median current CD4 was 29%, and 89% had VS. Seroprotection against JE virus was identified in 28 (29%) adolescents; of whom, the geometric mean titer (GMT) of neutralizing antibody was 64 (95% CI: 39–106). Proportion of adolescents with JE seroprotection and GMT of neutralizing antibodies to JE virus slightly decreased over time after the last immunization (Figure 1). In a multivariable logistic regression analysis, seroprotection against JE virus was associated with younger age and greater current CD4 count (Table 1). Conclusion The majority of our perinatally HIV-infected adolescents did not maintain seroprotection against JE virus although having completed a series of MBDV during childhood. JE revaccination is an important tool for disease prevention in these adolescents who live in JE endemic areas. Disclosures All authors: No reported disclosures.

scholarly journals Facemask wearing to prevent COVID-19 transmission and associated factors among taxi drivers in Dessie City and Kombolcha Town, Ethiopia

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247954
Author(s):  
Tarikuwa Natnael ◽  
Yeshiwork Alemnew ◽  
Gete Berihun ◽  
Masresha Abebe ◽  
Atsedemariam Andualem ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Odds Ratio ◽  
Associated Factors ◽  
Multivariable Analysis ◽  
World Health ◽  
Multivariable Logistic Regression Analysis ◽  
Taxi Drivers ◽  
Targeted Interventions

Background The World Health Organization (WHO) has pointed out that urban taxi drivers and their passengers are at higher risk of transmitting coronavirus disease 19 (COVID-19) due to frequent contact among many people. Facemask wearing is one of the preventive measures recommended to control the transmission of the virus. A lack of evidence of the proportion of facemask wearing among taxi drivers and associated factors in Ethiopia, including Dessie City and Kombolcha Town, hinders the design of targeted interventions to advocate for facemask use. This study was designed to address this gap. Methods A cross-sectional study was conducted among 417 taxi drivers in Dessie City and Kombolcha Town from July to August, 2020. The study participants were selected using a simple random sampling technique after proportionally allocating the sample size from the total number of taxi drivers working in Dessie City and Kombolcha Town. The data were collected by trained data collectors using a structured questionnaire and an on-the-spot observational checklist. The collected data were checked, coded and entered to EpiData version 4.6 and exported to Statistical Package for Social Sciences (SPSS) version 25.0 for data cleaning and analysis. Bivariate (Crude Odds Ratio [COR]) and multivariable (Adjusted Odds Ratio [AOR]) logistic regression analyses were employed using 95% CI (confidence interval). From bivariate logistic regression analysis, variables with p-value < 0.250 were retained into multivariable logistic regression analysis. Then, from the multivariable analysis, variables with p-value < 0.050 were declared as factors significantly associated with facemask wearing among taxi drivers in Dessie City and Kombolcha Town. Main findings The proportion of taxi drivers who wore a facemask was 54.68% [95%CI: 50.10–59.7%]. The majority (58.3%) of drivers were using cloth facemasks, followed by N95 facemasks (24.5%) and surgical facemasks (17.3%). Out of the total 417 taxi drivers, more than two-thirds (69.8%) of them had a good knowledge about COVID-19 and 67.6% of taxi drivers had a positive attitude towards taking precautions against transmission of COVID-19. Three-fourths (74.1%) of the taxi drivers believed that wearing a facemask could prevent COVID-19. More than half (52.5%) felt discomfort when wearing a facemask. Almost three-fourths (72.2%) of taxi drivers felt that the presence of local government pressure helped them to wear a facemask. We found that marital status [AOR = 3.14, 95%CI: 1.97–5.01], fear of the disease [AOR = 2.1, 95%CI: 1.28–3.47], belief in the effectiveness of a facemask [AOR = 5.6, 95%CI: 3.1–10.16] and feeling government pressure [AOR = 3.6, 95%CI: 2.16–6.13] were factors significantly associated with wearing a facemask. Conclusion We found that the proportion of facemask wearers among taxi drivers was relatively low in Dessie City and Kombolcha Town. In order to increase that number, government bodies should work aggressively to encourage more taxi drivers to wear a facemask. We also recommend that government and non-government organizations work very closely together to implement strategies that promote facemask use, including increasing the availability of inexpensive facemasks, and monitoring and controlling facemask use.

scholarly journals Associated Factors of Plasmodium Knowlesi Malaria among Registered Malaria Cases in Terengganu, Malaysia 2011- September 2019 via Vekpro Online Database

2021 ◽  
Vol 6 (2) ◽  
pp. 23-35
Author(s):  
Faizul Haris Hatta ◽  
Zaliha Ismail ◽  
Zahir Izuan Azhar ◽  
Nurhuda Ismail ◽  
Norafidah Abdul Rashid ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Mixed Infection ◽  
Associated Factors ◽  
Plasmodium Knowlesi ◽  
Multiple Logistic Regression Analysis ◽  
Weather Data ◽  
Multivariable Logistic Regression Analysis ◽  
Online Database

Introduction: Plasmodium knowlesi (P. knowlesi), zoonotic malaria cases had been increasing in trend in Terengganu, Malaysia. This study aimed to determine the associated factors of P. knowlesi malaria among registered malaria cases in Terengganu from 2011 to September 2019 via the Vekpro Online Database. Methods: A cross-sectional study was conducted using registered malaria cases in Terengganu from 2011 to September 2019 extracted from the Vekpro Online database and secondary weather data from the Malaysian Meteorological Department. A total sample of 247 malaria cases [(P. knowlesi (n=187), P. falciparum (n=23), P. vivax (n=37), P. malariae (n=4), mixed infection (n=3)] were analysed. The cases were grouped into P. knowlesi group (P. knowlesi, P. malariae, mixed infection) and non-P. knowlesi group (P. falciparum, P. vivax) for comparison of their risk factors. Multiple Logistic Regression analysis was used to identify the associated factors. Results: Plasmodium knowlesi group contributed to 187 out of 247 (75.7%) of all malaria cases. Four factors were found to be significantly associated with P. knowlesi group in the final multivariable logistic regression analysis. Age [AOR=1.04 (95% CI: 1.01,1.08)], Malay race [AOR=39.43 (95% CI: 13.99,111.18)], agriculture and forestry worker [AOR=14.95 (95% CI: 4.10,54.51)] and Passive Case Detection [AOR=11.70 (95% CI: 2.60,52.63)] were the significant associated factors. Conclusion: Identified significant associated factors and characteristics of the high-risk group for P. knowlesi infection can help medical and health front liners in Terengganu in early diagnosis and prompt treatment of the cases. The factors also will help in the planning and development of health interventions in targeting P. knowlesi infection.

scholarly journals Minimum acceptable diet practice and its associated factors among children aged 6–23 months in rural communities of Goncha district, north West Ethiopia

BMC Nutrition ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Bamlaku Birie ◽  
Andargachew Kassa ◽  
Emnet Kebede ◽  
Bezabih Terefe
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Rural Communities ◽  
Rural Community ◽  
Logistic Regression Analysis ◽  
Associated Factors ◽  
Institutional Delivery ◽  
Multivariable Logistic Regression Analysis ◽  
Amhara Region ◽  
Multivariable Logistic Regression

Abstract Background After the first 6 months breast milk is no longer sufficient to meet the nutritional needs of the infant. Therefore, complementary foods should be added to the child’s diet. Feeding children with a diversified diet is practiced improperly in developing countries including Ethiopia particularly in the rural community of the Amhara region. However, limited information was documented on the rural communities and no data were available specifically in the study area to show the exact picture of child feeding practices. So, this study was planned to assess minimum acceptable diet practice and its associated factors among children aged 6–23 months in the rural community of Goncha district, Amhara region, Ethiopia. Methods Community-based cross-sectional study was employed to determine minimum acceptable diet practice and its associated factors among children aged 6–23 months at rural communities of Goncha district, East Gojjam zone, Amhara region, Ethiopia. A multi-stage sampling technique was used to select study subjects, and an interview administered structured questionnaire was used to collect the data. Data were entered by Epi Data version 4.0.2 and exported to SPSS 20 for analysis. Bivariate and multivariable logistic regression analysis was used to see the association. Then, P-value < 0.05 with 95% CI on multivariable logistic regression analysis were used to identify the predictor of the outcome variable. Results A total of 430 mothers who have children aged 6–23 months were included in the analysis with a 98% of response rate. About 12.6% of children aged 6–23 months received the recommended minimum acceptable diet. Children whose mothers who had formal education [AOR = 2.7, 95%CI (1.133, 6.231)], institutional delivery [AOR = 4.5, 95%CI (1.986, 10.362)], media exposure [AOR = 2.6, 95%CI (1.303, 5.291)] and higher household wealth index [AOR = 2.5, 95%CI (1.139, 5.90)] were significantly associated with minimum acceptable diet. Conclusion The practice of minimum acceptable diet in the study area was inadequate and very low according to the national recommendation. So, strengthening institutional delivery, improving the wealth of the community and exposure to media, and finally empowering women’s’ for education is recommended.

scholarly journals Minimum Acceptable Diet Practice and its Associated Factors among Children’s Aged 6–23 Months in Rural Communities of Goncha District, North West Ethiopia, 2020

2020 ◽  
Author(s):  
Birie ◽  
Kassa ◽  
Mrs Kebede
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Rural Communities ◽  
Logistic Regression Analysis ◽  
Associated Factors ◽  
Institutional Delivery ◽  
Household Wealth ◽  
Outcome Variable ◽  
Multivariable Logistic Regression Analysis ◽  
Multivariable Logistic Regression

Abstract Introduction: After the first 6 months breast milk is no longer sufficient to meet the nutritional needs of the infant. Therefore, complementary foods should be added to the child’s diet. Feeding children’s with diversified diet is practiced improperly in developing countries including Ethiopia particularly in the rural community. Interventions are intended to undertake the nutrition problems in children in the country. However, the progress was not satisfactory, particularly; minimum acceptable diet has increased from 3% to 7% in a decade (2005-2016). Objective: To determine the proportion of minimum acceptable diet practice and its associated factors among children’s aged 6-23 months in rural communities of Goncha district, 2020Methodology: Community based cross-sectional study was employed at rural communities of Goncha district from June 15 to July 15 2020. Multi stage sampling technique was used to select study subjects, and interview administered structured questionnaire was used to collect the data. Data was entered by Epi Data version 4.0.2 and exported to SPSS 20 for analysis. Bivariate and multivariable logistic regression analysis was used to see the association between minimum acceptable diet and independent variable. Then, P-value <0.05 with 95% CI on multivariable logistic regression analysis were used to identify the independent predictor of outcome variable Result: A total of 430 mothers who have children aged 6-23 months were included in the analysis with 98% of response rate. About 12.6% of children’s aged 6-23 months received the recommended minimum acceptable diet. Children whose mothers who had formal education [AOR= 2.7, 95%CI (1.133, 6.231)], institutional delivery [AOR= 4.5, 95%CI (1.986, 10.362)], media exposure [AOR=2.6, 95%CI (1.303, 5.291)] and higher household wealth index [AOR= 2.5, 95%CI (1.139, 5.90)] were significantly associated with minimum acceptable diet.Conclusion: The practice of minimum acceptable diet in the study area was inadequate and very low according to notional and world health organization’s recommendation. So, strengthening institutional delivery, improving the wealth of the community and exposure to media, and finally empowering women’s for education are recommended.

scholarly journals Prediction of successful de-cannulation of tracheostomised patients in medical intensive care units

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Chul Park ◽  
Ryoung-Eun Ko ◽  
Jinhee Jung ◽  
Soo Jin Na ◽  
Kyeongman Jeon
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Goodness Of Fit ◽  
Characteristic Curve ◽  
Multivariable Logistic Regression Analysis ◽  
Limited Data ◽  
Underlying Malignancy ◽  
Medical Intensive Care ◽  
Good Calibration

Abstract Background Limited data are available on practical predictors of successful de-cannulation among the patients who undergo tracheostomies. We evaluated factors associated with failed de-cannulations to develop a prediction model that could be easily be used at the time of weaning from MV. Methods In a retrospective cohort of 346 tracheostomised patients managed by a standardized de-cannulation program, multivariable logistic regression analysis identified variables that were independently associated with failed de-cannulation. Based on the logistic regression analysis, the new predictive scoring system for successful de-cannulation, referred to as the DECAN score, was developed and then internally validated. Results The model included age > 67 years, body mass index < 22 kg/m2, underlying malignancy, non-respiratory causes of mechanical ventilation (MV), presence of neurologic disease, vasopressor requirement, and presence of post-tracheostomy pneumonia, presence of delirium. The DECAN score was associated with good calibration (goodness-of-fit, 0.6477) and discrimination outcomes (area under the receiver operating characteristic curve 0.890, 95% CI 0.853–0.921). The optimal cut-off point for the DECAN score for the prediction of the successful de-cannulation was ≤ 5 points, and was associated with the specificities of 84.6% (95% CI 77.7–90.0) and sensitivities of 80.2% (95% CI 73.9–85.5). Conclusions The DECAN score for tracheostomised patients who are successfully weaned from prolonged MV can be computed at the time of weaning to assess the probability of de-cannulation based on readily available variables.

scholarly journals Prevalence of postural deviations and associated factors in children and adolescents: a cross-sectional study

2016 ◽  
Vol 29 (4) ◽  
pp. 777-786 ◽  
Author(s):  
Mariana Vieira Batistão ◽  
Roberta de Fátima Carreira Moreira ◽  
Helenice Jane Cote Gil Coury ◽  
Luis Ernesto Bueno Salasar ◽  
Tatiana de Oliveira Sato
Keyword(s):  
Physical Activity ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Associated Factors ◽  
Multiple Logistic Regression Analysis ◽  
Extrinsic Factors ◽  
Cross Sectional ◽  
Postural Changes ◽  
Intrinsic And Extrinsic Factors

Abstract Introduction: Postural deviations are frequent in childhood and may cause pain and functional impairment. Previously, only a few studies have examined the association between body posture and intrinsic and extrinsic factors. Objective: To assess the prevalence of postural changes in school children, and to determine, using multiple logistic regression analysis, whether factors such as age, gender, BMI, handedness and physical activity might explain these deviations. Methods: The posture of 288 students was assessed by observation. Subjects were aged between 6 and 15 years, 59.4% (n = 171) of which were female. The mean age was 10.6 (± 2.4) years. Mean body weight was 38.6 (± 12.7) kg and mean height was 1.5 (± 0.1) m. A digital scale, a tapeline, a plumb line and standardized forms were used to collect data. The data were analyzed descriptively using the chi-square test and logistic regression analysis (significance level of 5%). Results: We found the following deviations to be prevalent among schoolchildren: forward head posture, 53.5%, shoulder elevation, 74.3%, asymmetry of the iliac crests, 51.7%, valgus knees, 43.1%, thoracic hyperkyphosis, 30.2%, lumbar hyperlordosis, 37.2% and winged shoulder blades, 66.3%. The associated factors were age, gender, BMI and physical activity. Discussion: There was a high prevalence of postural deviations and the intrinsic and extrinsic factors partially explain the postural deviations. Conclusion: These findings contribute to the understanding of how and why these deviations develop, and to the implementation of preventive and rehabilitation programs, given that some of the associated factors are modifiable.

scholarly journals Impact of histologic chorioamnionitis on pulmonary hypertension and respiratory outcomes in preterm infants

2018 ◽  
Vol 8 (2) ◽  
pp. 204589401876016 ◽  
Author(s):  
Sook Kyung Yum ◽  
Min-Sung Kim ◽  
Yoojin Kwun ◽  
Cheong-Jun Moon ◽  
Young-Ah Youn ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Preterm Infants ◽  
Logistic Regression Analysis ◽  
Multivariable Logistic Regression Analysis ◽  
Multivariable Logistic Regression ◽  
Histologic Chorioamnionitis ◽  
Respiratory Outcomes ◽  
Lower Birthweight

We aimed to evaluate the association between the presence of histologic chorioamnionitis (HC) and development of pulmonary hypertension (PH) during neonatal intensive care unit (NICU) stay. Data of preterm infants born at 32 weeks of gestation or less were reviewed. The development of PH and other respiratory outcomes were compared according to the presence of HC. Potential risk factors associated with the development of PH during NICU stay were used for multivariable logistic regression analysis. A total of 188 infants were enrolled: 72 in the HC group and 116 in the no HC group. The HC group infants were born at a significantly shorter gestational age and lower birthweight, with a greater proportion presenting preterm premature rupture of membrane (pPROM) > 18 h before delivery. More infants in the HC group developed pneumothorax ( P = 0.008), and moderate and severe bronchopulmonary dysplasia (BPD; P = 0.001 and P = 0.006, respectively). PH in the HC group was significantly more frequent compared to the no HC group (25.0% versus 8.6%, P = 0.002). Based on a multivariable logistic regression analysis, birthweight ( P = 0.009, odds ratio [OR] = 0.997, 95% confidence interval [CI] = 0.995–0.999), the presence of HC ( P = 0.047, OR = 2.799, 95% CI = 1.014–7.731), and duration of invasive mechanical ventilation (MV) > 14 days ( P = 0.015, OR = 8.036, 95% CI = 1.051–43.030) were significant factors. The presence of HC and prolonged invasive MV in infants with lower birthweight possibly synergistically act against preterm pulmonary outcomes and leads to the development of PH. Verification of this result and further investigation to establish effective strategies to prevent or ameliorate these adverse outcomes are needed.

Abstract 1847: Prognostic Impact Of Previous Percutaneous Coronary Interventions On Coronary Artery Bypass Graft Surgery: A Multicentric Analysis FromThe German Federal State North-Rhine-Westphalia

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Parwis Massoudy ◽  
Matthias Thielmann ◽  
Nils Lehmann ◽  
Anja Marr ◽  
Georg Kleikamp ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Coronary Artery ◽  
Hospital Mortality ◽  
Logistic Regression Analysis ◽  
Artery Bypass ◽  
Federal State ◽  
Multivariable Logistic Regression Analysis ◽  
Percutaneous Coronary ◽  
German Federal State

Background: We have previously shown that multiple prior percutaneous coronary intervention (PCI) procedures adversely affect outcome after subsequent coronary artery bypass grafting (CABG). We were now interested to investigate this effect on a multicentric basis. Methods: Eight cardiac surgical centers from the German Federal State of North-Rhine-Westphalia provided outcome data of 37140 consecutive patients having undergone isolated first-time CABG between 01/2000 and 12/2005. Twenty-two patient characteristics and outcome variables, which are part of a collection of data claimed by the national medical quality-control commission, were retrieved from the individual databases. Three groups of patients were analyzed for overall in-hospital mortality and major adverse cardiac events (MACE): Patients without a previous PCI procedure, patients with 1 previous PCI procedure and patients with ≥2 previous PCI procedures before surgery. Unadjusted univariable and risk-adjusted multivariable logistic regression analysis were applied. Computed propensity-score matching was performed based on 15 patient major risk factors to correct for and minimize selection bias. Results: A total of 10.3% of patients had 1 previous PCI procedure, and 3.7% of patients had ≥2 previous PCI procedures. Risk-adjusted multivariable logistic regression analysis of ≥2 previous PCI significantly correlated with in-hospital mortality (odds ratio [OR], 2.0; confidence interval [CI], 1.4–3.0; P <0.0005) and MACE (OR, 1.5; CI, 1.2–1.9; P <0.0013). After propensity score matching, conditional logistic regression analysis confirmed the results of adjusted analysis. A history of ≥2 previous PCI procedures was significantly associated with in-hospital mortality (OR, 1.9; CI, 1.3–2.7; P =0.0016) and MACE (OR, 1.5; CI, 1.2–1.9; P =0.0019). Conclusions: This large multicentric trial supports earlier results of our single-center analysis, multiple previous PCI procedures significantly increased the event of in-hospital mortality and MACE after subsequent CABG.

Abstract TP3: Early Reocclusion After Mechanical Thrombectomy for Acute Stroke Due to Intracranial Atherosclerotic Stenosis-Related Occlusions

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Masatomo Miura ◽  
Yoichiro Nagao ◽  
Makoto Nakajima ◽  
Seigo Shindo ◽  
Kuniyasu Wada ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Balloon Angioplasty ◽  
Mechanical Thrombectomy ◽  
Rescue Therapy ◽  
Multivariable Logistic Regression Analysis ◽  
Intracranial Stenting ◽  
Atherosclerotic Stenosis

Background: In acute ischemic stroke (AIS) patients due to intracranial atherosclerosis-related occlusions (ICAS-O), despite successful reperfusion with mechanical thrombectomy (MT), unexpected early reocclusion sometimes occurs and worsens clinical outcome. We investigated prevalence, outcomes, and predictors of early reocclusion within 48 hours of MT in AIS due to ICAS-O. Methods: In 557 consecutive AIS patients who underwent MT from January, 2016 to March, 2019 in two stroke centers, 71 patients due to ICAS-O were retrospectively evaluated. We divided them into two groups: patients with early reocclusion and those without. Clinical and angiographical findings and outcomes were compared between the 2 groups. Multivariable logistic regression analysis was used to investigate predictors of early reocclusion after MT. Results: Of 71 patients (aged 72 ± 10 years; 23 women; median NIHSS score, 15), early reocclusion was observed in 11 (15%). The first procedure for recanalization was stent retriever in 25 patients (35%), Penumbra system in 25 patients (35%), and balloon angioplasty in 21 patients (30%). Of these, 63 patients (88%) received rescue therapy (balloon angioplasty, 50; intracranial stenting, 13). In the early reocclusion group, more number of intraprocedural reocclusion (median [IQR], 3 [2-3] vs. 1 [0-1], p < 0.001), a higher rate of remaining stenosis on the final angiography (67.6 ± 5.9% vs 57.3 ± 15.9%, p = 0.044), and a higher rate of procedure-related adverse events (27% vs 5%, p = 0.043) were observed compared to the other group. On logistic regression analysis, a total number of intraprocedural reocclusion was independently associated with early reocclusion (odds ratio, 31.4; 95% confidence interval, 2.6-375.2). Early reocclusion was related to a low rate of favorable outcome at 90 days (modified Rankin Scale ≤ 2, 9% vs 54%, p = 0.007). Conclusions: In AIS patients due to ICAS-O, early reocclusion within 48 hours was not rare and associated with unfavorable outcome. Patients with repeated intraprocedural reocclusion are at high risk for early reocclusion; they might need follow-up angiographical assessment and intensive antithrombotic treatment.

Sign in / Sign up

Export Citation Format

Share Document