Rhythm (Exercises 41–60)

2021 ◽  
pp. 43-60
Author(s):  
Jorge Variego

Rhythm in this chapter is conceived as the pace at which music unfolds in time. Note values, rests, and other sources of rhythmic notation are a way to control the temporal evolution of a new composition. Exercise 41 proposes a series of simple mathematical transformations to given rhythmic structures; 42 and 43 use segments of equal and unequal length. Numbers 44 and 45 incorporate the concept of non-retrogradable rhythmic structures, the goal of 46 is to extract the rhythm of a given text using its syllables and accents, 47 uses groupings to generate meter, and 48 uses a Morse code translator to extract the durations from a given text. Exercise 49 brings back the concept of rhythmic ostinato; 50 and 51 employ hemiolas. Number 52 is based on the use of several time signatures simultaneously (polymeter), 53 incorporates metric modulations, and 54 uses rhythmic motifs as building blocks. Number 55 continues with the use of motifs, shifting them in time. The concepts of talea and color from isorhythmic motets are included in exercise 56. Looping and composing using repeat signs are included in number 57; 58 is about indeterminate pauses and fermatas. Rhythmic transformations using eliminations are at the core of 59; exercise 60 proposes an experimentation with the perception of pulse.

2019 ◽  
Vol 16 (12) ◽  
pp. 1348-1353
Author(s):  
Huanhuan Qu ◽  
Baixue Li ◽  
Jingyi Yang ◽  
Huaiwen Liang ◽  
Meixia Li ◽  
...  

Background: Disaccharide core 1 (Galβ1-3GalNAc) is a common O-glycan structure in nature. Biochemical studies have confirmed that the formation of the core 1 structure is an important initial step in O-glycan biosynthesis and it is of great importance for human body. Objective: Our study will provide meaningful and useful sights for O-glycan synthesis and their bioassay. And all the synthetic glycosides would be used as intermediate building blocks in the scheme developed for oligosaccharide construction. Methods: In this article, we firstly used chemical procedures to prepare core 1 and its derivative, and a novel disaccharide was efficiently synthesized. The structures of the synthesized compounds were elucidated and confirmed by 1H NMR, 13C NMR and MS. Then we employed three human gut symbionts belonging to Bacteroidetes, a predominantphyla in the distal gut, as models to study the bioactivity of core 1 and its derivative on human gut microbiota. Results: According to our results, both core 1 and derivative could support the growth of B. fragilis, especially the core 1 derivative, while failed to support the growth of B. thetaiotaomicron and B. ovatus. Conclusion: This suggested that the B. fragilis might have the specificity glycohydrolase to cut the glycosidic bond for acquiring monosaccharide.


Author(s):  
Hazel Gray

This chapter sets out the analytical framework of political settlements and elaborates the framework to account for the socialist experiences of Tanzania and Vietnam in the 1960s and 1970s. A political settlement, as defined by Mushtaq Khan, is a combination of power and institutions that is mutually compatible and also sustainable in terms of economic and political viability. The chapter clarifies the core building blocks of the approach and sets out the main differences between political settlements and new institutional economics. The chapter then defines a socialist political settlement where productive rights are formally held by the collective and formal institutions protect common and collectively owned assets. The attempts to construct a socialist political settlement left important institutional, political, and economic legacies. These shaped incentives and constraints which influenced a number of critical processes at the heart of economic development—related to technological learning, accumulation for investment, and political stabilization.


Author(s):  
Gary W. Morrow

We have already seen that some of the basic building blocks used in the biosynthesis of natural products are amino acids such as phenylalanine, tyrosine, and others. These and other crucial construction materials such as the acyl group in acetyl-CoA are all ultimately derived from carbohydrates. In this chapter, we will present an abbreviated overview of the components of carbohydrate structure and metabolism sufficient for our purposes going forward, with a schematic flowchart showing how carbohydrates and amino acids are modified, combined, and branched off in various ways to yield the distinct set of biosynthetic pathways that will form the core of the remainder of the text. We will finish the chapter with a brief, general review of amino acid nomenclature and structure with emphasis on the key amino acids that will be used throughout the remainder of the text. We know that plants make glucose (C6H12O6) by photosynthesis using light, water (H2O), and carbon dioxide (CO2). Another way of looking at the formula for glucose is C6(H2O)6, that is, six carbon atoms and six water molecules. Thus, glucose was originally referred to as a hydrated form of carbon—a carbohydrate. But this is a very general term since there are many different types of carbohydrate compounds. One way to broadly classify carbohydrates is to identify them as either mono- (one), di- (two), oligo- (a few) or poly- (many) saccharides. For example, glucose (C6H12O6) cannot be broken down into simpler carbohydrates by simple hydrolysis, so it is classified as a monosaccharide, that is, a single, discrete carbohydrate compound. On the other hand, the carbohydrate sucrose (C12H22O11) is classified as a disaccharide since when it is subjected to aqueous hydrolysis, it yields two different monosaccharide carbohydrates, namely glucose (C6H12O6) and fructose (C6H12O6). Noting that glucose and fructose are different compounds but with the same molecular formula, they must be related to one another either as stereoisomers or as constitutional isomers, so further refinement of classification is needed. Structurally speaking, most monosaccharide carbohydrates are simply polyhydroxyaldehydes (aldoses) or polyhydroxyketones (ketoses) which can be further classified using a combination of aldo- or keto- prefixes along with suffixes such as triose, tetrose, pentose, or hexose to designate the number of carbon atoms.


2019 ◽  
Vol 33 (6) ◽  
pp. 1894-1952 ◽  
Author(s):  
Jadson Castro Gertrudes ◽  
Arthur Zimek ◽  
Jörg Sander ◽  
Ricardo J. G. B. Campello

Abstract Semi-supervised learning is drawing increasing attention in the era of big data, as the gap between the abundance of cheap, automatically collected unlabeled data and the scarcity of labeled data that are laborious and expensive to obtain is dramatically increasing. In this paper, we first introduce a unified view of density-based clustering algorithms. We then build upon this view and bridge the areas of semi-supervised clustering and classification under a common umbrella of density-based techniques. We show that there are close relations between density-based clustering algorithms and the graph-based approach for transductive classification. These relations are then used as a basis for a new framework for semi-supervised classification based on building-blocks from density-based clustering. This framework is not only efficient and effective, but it is also statistically sound. In addition, we generalize the core algorithm in our framework, HDBSCAN*, so that it can also perform semi-supervised clustering by directly taking advantage of any fraction of labeled data that may be available. Experimental results on a large collection of datasets show the advantages of the proposed approach both for semi-supervised classification as well as for semi-supervised clustering.


Symmetry ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1510
Author(s):  
Renato Dalpozzo ◽  
Raffaella Mancuso

Benzopyran and benzodihydropyran (chromane) nuclei are the core structure of many natural products, in particular flavonoids. Many compounds possessing this structure are nutraceuticals, pharmaceutical nutrients. Therefore, benzopyran and chromane scaffolds are important building blocks in organic synthesis and many efforts have been made to set up efficient methods for their synthesis. In particular, asymmetric methods are of great importance, being natural products, and generally chiral substances. This review aims to cover literature in the range 2017–first half of 2019.


Author(s):  
David J. Teece ◽  
Olga Petricevic

In this chapter we argue that traditional approaches to modeling the growth of the multinational enterprise (MNE) that focus on costs and efficiencies are too narrow to adequately and comprehensively address the foundations of MNE growth trajectories. Today’s global realities and the changing view of the MNE require a more focused and explicit capability-based perspective. In particular, we posit that contemporary theories of the MNE require frameworks and explanations that should simultaneously account for the uncertainties that firms face in their external environment and the complexities of often competing internal, organizational alternatives. To develop our reasoning in support of capability-based thinking, we discuss the changing nature on the international business (IB) landscape, the evolving views on the nature of the MNE, and present the core building blocks of capability-based thinking in managing MNE growth. We conclude the chapter by offering some thoughts on how capability-based thinking could be applied in future scholarly efforts.


Author(s):  
Sergio Scanu ◽  
Francesco Paladini de Mendoza ◽  
Daniele Piazzolla ◽  
Marco Marcelli

AbstractIn this study, sedimentological and geochronological data from sections of a core (GRT50) collected in the Northern Latium coastal area were compared to data on pluviometric (rainfall) trends, river flows and the temporal evolution of human interventions in the three most important hydrographic basins (Mignone, Marta and Fiora) of this coastal area. The statistical analysis of pluviometric trends identified variations due to a decreasing trend in the Fiora river basin, whereas in the two other locations the decrease was not so significant. Data from the sedimentological analysis of the core confirmed a progressive decrease in the sandy component, which declined from about 30% to the current level of 7% over the last 36 years. There was no significant variation in the sediment mass accumulation rates (MAR), which were characterized by an almost cyclic trend that was probably determined by the most intense floods in the study area. The results revealed that the variations caused by the fluvial processes have affected the water runoff of the Fiora River, and that the consequent decrease in the sand production has been responsible for the recession of beaches in the coastal area between Tarquinia and Montalto di Castro.


Nanoscale ◽  
2014 ◽  
Vol 6 (22) ◽  
pp. 13483-13486 ◽  
Author(s):  
D. Llamosa ◽  
M. Ruano ◽  
L. Martínez ◽  
A. Mayoral ◽  
E. Roman ◽  
...  

Core@shell and core@shell@shell nanoparticles are building blocks for more sophisticated systems and a plethora of applications. The one-step generation of such complex nanoparticles is reported where the atoms of the core and shell can be easily inverted, avoiding intrinsic constraints of chemical methods.


2021 ◽  
Author(s):  
◽  
Jessie Williams

<p>This thesis focuses critically on contemporary theory and practice of peace-building where there has been conflict. The commonality of the resumption of violence after peace processes in many recent examples, suggests that both theory and practice have not worked as intended. The thesis explores insights that might improve the odds that governing institutions (or, more particularly, the people who work in them) can put aside violence. In the terms used in this thesis: how might Leviathan be pacified? Therefore, the thesis deals with basics evident in all recorded (and probably pre-historic) human experience. For the modern states of Western Europe and North America, pacifying Leviathan followed centuries of conflict (including two world wars), interspersed with governance reforms and constitutional adjustments. The process is ongoing, but by the middle of the 20th century “the liberal state” clearly emerged, with features that included constitutions, the rule of law, the protection of human rights and the market system. There appeared to be a widespread view after World War II that the liberal state apparatus’ essence could be written down in documents, transplanted into many different historical and cultural contexts and would work much as the model predicted i.e. was easily reproducible, perhaps infinitely, even in smaller and smaller versions. From 1945 to 2010, the numbers of states at the United Nations almost quadrupled (51 to 192). Member 193 (South Sudan) may emerge from decades of conflict in 2011. In all that state formation, the optimistic view was that the new documents and institutions would provide structures within which political and/or ethnic competitors/combatants would engage in non-violent political competition. In this thesis, “reverse-engineering” is the term given to this notion. Such optimism was severely dented by the experiences of many newly-independent states in the mid-late 20th century. As violence escalated in new and existing states all over the world after the Cold War ended (taken, for convenience, as 1990), reverse-engineering remained at the core of the formula for peace-building after conflict. As with the post-colonial period, liberal peace-building since 1990 have also been repeated failures to work as intended, including the resumption of conflict. The most fragile states have posed the hardest problems, not only for the suffering citizens but for the international community seeking how best to help.  With this in mind, and accepting that each state and society is unique, this thesis sets out building blocks for alternative approaches. It does not suggest there are simple answers in pacifying Leviathan, either generally or in relation to any particular example. If it is indeed possible in any place (e.g. Haiti) to reduce ongoing conflict, the argument is that these blocks should be amongst the foundations of theory to inform practice.  The core thesis is thus that the chances of pacifying Leviathan might be significantly improved if domestic and international actors: • Adopt a conflict transformation approach to guide theory and practice; • Come to terms with groupism – how/why humans bond into groups and the potential this poses for violence and peace; • Understand the importance of receptivity - the notion that critical masses of key actors should squarely face (often when they have become exhausted by) the consequences of violent competitiveness and seek alternatives; • Translate receptivity into learned constitutionalism – learning to govern by rules amongst sufficient actors; and • Develop international assistance guided by the above perspectives, and which, with the consent of the peoples concerned, find ways to stay appropriately engaged for the time needed to strengthen the factors that should pacify Leviathan.  The thesis does not focus on future strategies of conflict-reduction – such as economic development to give people stakes in the society, along with disarmament of combatants. Many other studies explore these. Here, the exploration is of the nature of human society, informed by history, examples, case studies and a sweep of cross-disciplinary analysis. Understanding why pacifying Leviathan is so hard is the basic first step, which forms the bulk of this thesis. Putting such understanding into practice involves many further steps. Important as these might be for current and future policy and practice in peace-building, their full development is beyond the scope of this thesis. Some suggestions are made, especially in the conclusion, but elaboration will have to await further work.</p>


eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Jennifer J Banerjee ◽  
Birgit L Aerne ◽  
Maxine V Holder ◽  
Simon Hauri ◽  
Matthias Gstaiger ◽  
...  

Polarity is a shared feature of most cells. In epithelia, apical-basal polarity often coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the epithelial plane. From a limited set of core building blocks (e.g. the Par complexes for apical-basal polarity and the Frizzled/Dishevelled complex for PCP), a diverse array of polarized cells and tissues are generated. This suggests the existence of little-studied tissue-specific factors that rewire the core polarity modules to the appropriate conformation. In Drosophila sensory organ precursors (SOPs), the core PCP components initiate the planar polarization of apical-basal determinants, ensuring asymmetric division into daughter cells of different fates. We show that Meru, a RASSF9/RASSF10 homologue, is expressed specifically in SOPs, recruited to the posterior cortex by Frizzled/Dishevelled, and in turn polarizes the apical-basal polarity factor Bazooka (Par3). Thus, Meru belongs to a class of proteins that act cell/tissue-specifically to remodel the core polarity machinery.


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