Computer Assisted Collimation Gamma Camera: A New Approach to Imaging Contaminated Tissues

2000 ◽  
Vol 89 (3) ◽  
pp. 343-348
Author(s):  
M. Quartuccio ◽  
D. Franck ◽  
P. Pihet ◽  
S. Begot ◽  
C. Jeanguillaume
Keyword(s):  
Gamma Camera ◽  
Computer Assisted ◽  
New Approach

Computer-Based Thermodynamics

2002 ◽  
Vol 30 (4) ◽  
pp. 427-436
Author(s):  
Kenneth L. Tuttle ◽  
Chih Wu
Keyword(s):  
Parametric Analysis ◽  
Thermodynamic Cycle ◽  
Computer Assisted ◽  
Traditional Theory ◽  
Naval Academy ◽  
New Approach ◽  
Thermodynamic Cycles ◽  
Computer Based ◽  
Approach To Teaching ◽  
Assisted Instruction

A new computer-based approach to teaching thermodynamics is being developed and tried by two mechanical engineering professors at the U.S. Naval Academy. The course uses sophisticated software, in this case CyclePad, to work all of the homework problems. A new text, written with traditional theory but computer-based problems, accommodates the new approach. The new course is scheduled for Fall Term 2001 at the Naval Academy. Computer-based thermodynamics courses teach the same theory as traditional thermodynamics courses as well as the same types of problems. However, traditional thermodynamic cycle hand calculations are replaced by cycle calculations using CyclePad. This new example of Intelligent Computer-Assisted Instruction, ICAI, switches emphasis from learning cycle calculations to learning cause and effect through parametric analysis. Parametric analysis is made feasible through experimentation using computer models. For this, CyclePad has artificial intelligence, sensitivity analysis and graphical presentation capabilities. Traditionally, thermodynamics culminates in analysis of the thermodynamic cycles. In this course, students will progress well beyond traditional thermodynamics courses by emphasizing cycle analysis.

scholarly journals Optimisation of aquifer parameters: a case study from Bheri Terai area, mid western Nepal

1998 ◽  
Vol 18 ◽  
Author(s):  
Moti Bahadur Kunwor
Keyword(s):  
Groundwater Potential ◽  
Computer Assisted ◽  
Confined Aquifer ◽  
Numerical Techniques ◽  
Deep Aquifer ◽  
Piezometric Head ◽  
New Approach ◽  
Aquifer Parameters ◽  
Aquifer Characteristics

For the study of groundwater potential in any area, it is necessary to determine aquifer parameters as correctly as possible. The most effectively and popularly used tools in the field by groundwater geologists and engineers till today is old conventional curve techniques. A new approach is given to refine the aquifer characteristics by computer-assisted numerical techniques. The computer-assisted techniques were used in the Bheri Terai area (Banke/Bardiya), mid western Nepal with an objective of studying the aquifer parameters more accurately with reference to the prevailing hydrogeological condition. Keeping in view of the nature and types of aquifer, an optimisation based model developed by Jageshwar (1985) has been adopted for estimation of aquifer parameters. The aquifer parameters in the study area have been evaluated by using both curve procedure and computer assisted numerical techniques. Parameters are optimised by minimisation of sum of the square of residues between computed and observed drawdown. The starting values of parameter for optimisation were generally assigned as per the available graphical procedures. The applicability of the model to the field data has been demonstrated by using the existing test pumping data of Bheri Terai area (GWRDB, 1979). The purposed model for the analysis of test pumping data yields significantly better reproduction of time drawdowns. The results of analysis of test pumping data indicate confined and leaky confined nature of deep aquifer. Majority of leaky aquifers show a declining nature of piezometric head in the overlying aquifer while, some of the confined aquifer shows finite nature in areal extent due to the presence of barrier boundary (most probably impervious clay?).

scholarly journals A New Approach to the Evaluation of Peripheral Vascular Disease Using the Gamma Camera

Radiology ◽  
1974 ◽  
Vol 112 (1) ◽  
pp. 115-122 ◽  
Author(s):  
Henri A. Gerritsen ◽  
Ismail Kazem ◽  
Arie Hasman ◽  
Peter J. Kuypers
Keyword(s):  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Gamma Camera ◽  
Peripheral Vascular ◽  
New Approach

New approach for in vivo detection of insulitis in type I diabetes: activated lymphocyte targeting with 123I-labelled interleukin 2

1994 ◽  
Vol 131 (4) ◽  
pp. 431-437 ◽  
Author(s):  
Alberto Signore ◽  
Marco Chianelli ◽  
Elisabetta Ferretti ◽  
Anna Toscano ◽  
Keith E Britton ◽  
...  
Keyword(s):  
Gamma Camera ◽  
Type I Diabetes ◽  
Interleukin 2 ◽  
Nod Mice ◽  
Insulin Dependent Diabetes ◽  
Type I ◽  
New Approach ◽  
In Vivo Detection ◽  
Insulin Dependent

Signore A, Chianelli M, Ferretti E, Toscano A, Britton KE, Andreani D, Gale EAM, Pozzilli P. New approach for in vivo detection of insulitis in type I diabetes: activated lymphocyte targeting with 123I-labelled interleukin 2. Eur J Endocrinol 1994;131:431–7. ISSN 0804–4643 Insulitis is considered the histopathological hallmark of type I (insulin-dependent) diabetes. In the nonobese diabetic (NOD) mouse, diabetes has never been observed in the absence of insulitis. The in vivo detection of insulitis could be of relevance for early prediction of diabetes. As approximately 15% of islet-infiltrating lymphocytes express interleukin 2 receptors, we have labelled recombinant interleukin 2 with 123I and used this radiopharmaceutical to detect insulitis by gamma camera imaging. We studied 71 prediabetic NOD and 27 normal Balb/c mice. Labelled α-lactalbumin was used as the control protein. In the first set of experiments we studied the tissue distribution of radiolabelled interleukin 2 in isolated organs from animals sacrificed at different time points. Higher radioactivity was detected in the pancreas of NOD mice injected with labelled interleukin 2, as compared to NOD mice receiving labelled α-lactalbumin (p < 0.003 at 20 min; p< 0.001 at 40 min; p< 0.0001 at 60 min) or Balb/c mice injected with labelled interleukin 2 (p< 0.05 at 40 min; p< 0.001 at 60 min). In another set of experiments, gamma camera images have been acquired after injection of 123I-labelled interleukin 2. Radioactivity in the pancreatic region of prediabetic NOD and Balb/c mice showed similar kinetics to those observed by single organ counting, with higher accumulation in the pancreatic region of NOD mice (p < 0.04 after 22–45 min in NOD mice vs Balb/c mice). Finally, a positive correlation was found between the radioactivity in the pancreas and the extent of lymphocytic infiltration (p < 0.01 for pancreas radioactivity counted in vitro and p< 0.004 for pancreas radioactivity counted in vivo by gamma camera). This study demonstrates that 123I-labelled interleukin 2 administered iv accumulates specifically in the inflamed pancreas of diabetes-prone NOD mice, suggesting its potential application in human insulin-dependent diabetes mellitus. A Signore, Servizio Speciale di Medicina Nucleare, II Clinica Medica, Policlinico Umberto I, 00161 Roma, Italy

Plastination: A New Approach to Morphological Research and Instruction with Excised Larynges

1993 ◽  
Vol 102 (9) ◽  
pp. 660-665 ◽  
Author(s):  
Hans Edmund Eckel ◽  
Christian Sittel ◽  
Martin Walger ◽  
Georg Sprinzl ◽  
Jürgen Koebke
Keyword(s):  
Tumor Invasion ◽  
Gross Anatomy ◽  
Computer Assisted ◽  
New Approach ◽  
Different Types ◽  
Clear Identification ◽  
Band Saw ◽  
First Time ◽  
Morphological Research ◽  
Complete Process

Impregnation of biologic materials with curable polymer (plastination) allows wider use of human tissue for both basic and clinical research and instruction. The aim of this study was to determine for the first time the potential of this method in the field of laryngology. A feasibility study on 54 pig larynges established a detailed methodology for larynx plastination and determined the extent of shrinkage by using computer-assisted morphometry. The process involves dehydration, saturation with an appropriate intermediate solvent, and infiltration with cured polymer in vacuo. In the main study 20 fresh, intact human larynges and 12 laryngectomy specimens were submitted to plastination. The resulting resin blocks were cut with a diamond band saw into 0.8-mm sections in the transaxial plane. The resulting specimens are dry, odorless, and durable, and do not deteriorate with time. The subtle features of soft tissue pathology are well preserved. Shrinkage of plastinated larynges is less than 10%. The complete process is accomplished within 5 weeks. Staining of sections with toluidine blue provides an enhanced contrast between different types of tissue, allowing a clear identification of tumor invasion. Plastination is considerably faster than celloidin embedding and causes minor anatomic changes. It provides durable specimens of high quality for teaching purposes. In research, it allows the investigation of all tissue components in their undisturbed context in the borderline area between gross anatomy and histology.

Computer-Assisted Assembly Language Programming Laboratory

2007 ◽  
Vol 44 (3) ◽  
pp. 216-229 ◽  
Author(s):  
Santiago Rodríguez ◽  
José L. Pedraza ◽  
Antonio García ◽  
Francisco Rosales ◽  
Rafael Méndez
Keyword(s):  
Computer Architecture ◽  
Assembly Language ◽  
Laboratory Work ◽  
Computer Assisted ◽  
Plagiarism Detection ◽  
Tool Chain ◽  
New Approach ◽  
A Chain ◽  
Assembly Language Programming ◽  
Work Management

This paper presents a new approach for managing laboratory work mini-projects that is used in the Computer Architecture Department of the Technical University of Madrid (UPM). The approach is based on a chain of tools (a Delivery Agent; an Automatic Project Evaluator; and a Plagiarism Detection Assistant) that a small number of teachers can use to efficiently manage a course with a large number of students (400 each year). Students use this tool chain to complete the Assembly Language Programming laboratory assignments using an MC88110 simulator built in our department. Jointly, these tools have demonstrated over the last decade what important benefits can be gained from the exploitation of a global laboratory work management system. Some of the benefits may have a continuation in an area of growing importance that we have not yet explored, such as distance learning environments for technical subjects.

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