scholarly journals 1035 Sleep Duration and Metabolic Syndrome: An Updated Systematic Review and Meta-Analysis

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A393-A393
Author(s):  
Y Li ◽  
J Xie ◽  
B Chen ◽  
M Basta ◽  
A Vgontzas
Keyword(s):  
Metabolic Syndrome ◽  
Longitudinal Studies ◽  
Sleep Duration ◽  
Medical Science ◽  
Development Program ◽  
Short Sleep Duration ◽  
Cross Sectional ◽  
Short Sleep ◽  
Long Sleep ◽  
Cross Sectional Studies

Abstract Introduction To systematically examine the association between sleep duration and metabolic syndrome (Mets) risk in cross-sectional and prospective cohort studies. Methods Data were collected from 36 cross-sectional and 9 longitudinal studies with a total of 164799 MetS subjects and 430895 controls. Odds ratios (ORs) for MetS in cross-sectional studies and risk ratios (RRs) for incident MetS were calculated through meta-analyses of adjusted data from individual studies. Subgroup analyses were performed to investigate the association between MetS and the duration of short-and-long sleep. Results Short sleep duration was significantly associated with increased prevalent MetS (OR= 1.11, 95% CI =1.05-1.18) and incident MetS (RR= 1.28, 95% CI =1.07-1.53,) in cross-sectional and longitudinal studies, respectively. Furthermore, long sleep duration was significantly associated with increased prevalent MetS in cross-sectional studies (OR= 1.14, 95% CI =1.05-1.23), rather than incident MetS (RR= 1.16, 95% CI =0.95-1.41) in longitudinal studies. Interestingly, the association between long sleep and prevalent MetS was found in sleep duration defined by 24-hour sleep (including naps) rather than nighttime sleep. In cross-sectional studies, pooled odds for MetS were 1.36 (95% CI=1.04-1.78, I2=83.3%) in ≤ 5 hours, 1.09 (95% CI=1.02-1.16, I2=67.8%) in ≤6 hours, 1.01 (95% CI=0.93-1.10, I2=24.9%) in <7 hours, 1.11 (95% CI=1.02-1.21, I2=67.0%) in ≥9 hours and 1.31 (95% CI=1.22-1.40, I2=0%) in ≥10 hours, respectively. The association of short sleep and MetS was stronger in young and middle age adults, but lost in adults age >60 years. Conclusion Our findings suggest 1) a “U-shape” relationship between sleep duration and MetS in cross-sectional studies and 2) association between short sleep duration, but not long sleep duration with incident MetS. Future studies should shed light on the underlying mechanisms related to the association between sleep duration and MetS and examine if normalizing sleep duration reduces MetS risk in the general population. Support This study was supported by National Natural Science Foundation of China (No. 81600068 & 81970087), the Young Elite Scientists Sponsorship Program by CAST (No. YESS20160072), Medical Science Foundation of Guangdong Provence (A2018296) and Grant for Key Disciplinary Project of Clinical Medicine under the Guangdong High-level University Development Program.

scholarly journals Sleep Duration and the Risk of Metabolic Syndrome in Adults: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Jianian Hua ◽  
Hezi Jiang ◽  
Hui Wang ◽  
Qi Fang
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Studies ◽  
Sleep Duration ◽  
Meta Analysis ◽  
Short Sleep Duration ◽  
Cross Sectional ◽  
Short Sleep ◽  
Increased Risk ◽  
Long Sleep ◽  
Cross Sectional Studies

Objective: Epidemiological studies have reported inconsistent findings for the association between sleep duration and metabolic syndrome. We aimed to clarify the effects of short and long sleep durations on metabolic syndrome in adults by performing a meta-analysis.Methods: Adopting random-effects models, this study analyzed the effects of short and long sleep durations based on data from prospective cohort studies and cross-sectional studies retrieved from four electronic databases from inception to May 2020.Results: We collected data from 235,895 participants included in nine prospective cohort studies and 340,492 participants included in 27 cross-sectional studies. In cohort studies, short sleep duration was associated with an increased risk of metabolic syndrome (RR, 1.15; 95% CI, 1.05–1.25, I2 = 63.1%, P < 0.001) compared with normal sleep duration. While long sleep duration was not associated with new-onset metabolic syndrome (RR, 1.02, 0.85–1.18, I2 = 38.0%, P = 0.491). In cross-sectional studies, both short (OR, 1.06, 95% CI, 1.01–1.11, I2 = 66.5%, P < 0.001) and long (OR, 1.11, 95% CI, 1.04–1.17, I2 = 73.8%, P < 0.001) sleep durations were associated with a high prevalence of metabolic syndrome.Conclusions: Only a short sleep duration was associated with an increased risk of metabolic syndrome. Future studies should address whether the association is casual and modifiable.

scholarly journals Sleep Duration and the Risk of Metabolic Syndrome: a Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Jianian Hua ◽  
Hezi Jiang ◽  
Qi Fang
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Studies ◽  
Sleep Duration ◽  
Meta Analysis ◽  
Epidemiologic Studies ◽  
Short Sleep Duration ◽  
Cross Sectional ◽  
Short Sleep ◽  
Increased Risk ◽  
Cross Sectional Studies

Objective: Epidemiologic studies have reported inconsistent findings about the association between sleep duration and metabolic syndrome. We aimed to clarify this association by method of meta-analysis. Methods: Medline, Embase, CINAHL and PsycINFO databases were searched from inception to May 2020. We collected data from 235,895 participants from 9 prospective cohort studies, and 340,492 participants from 26 cross-sectional studies. Risk ratios (RR) or odds ratios (OR) were calculated separately for cohort studies and cross-sectional studies, through meta-analysis of adjusted data from individual studies. Results: For cohort studies, short sleep duration was associated with an increased risk of metabolic syndrome (RR, 1.15; 95% CI, 1.05-1.25). Long sleep duration was not associated with new onset metabolic syndrome (RR, 1.02, 0.85-1.18). For cross-sectional studies, both short (OR, 1.12, 95% CI, 1.08-1.18) and long (OR, 1.06, 1.01-1.11) sleep duration was associated with high prevalence of metabolic syndrome. Conclusions: Only short sleep duration was associated with an increased risk of metabolic syndrome. Future studies should address whether the association is casual and modifiable.

scholarly journals Sleep Duration and Sleep Quality Are Associated with Physical Activity in Elderly People Living in Nursing Homes

2018 ◽  
Vol 15 (11) ◽  
pp. 2512 ◽  
Author(s):  
Lovro Štefan ◽  
Goran Vrgoč ◽  
Tomislav Rupčić ◽  
Goran Sporiš ◽  
Damir Sekulić
Keyword(s):  
Physical Activity ◽  
Nursing Homes ◽  
Sleep Quality ◽  
Sleep Duration ◽  
Short Sleep Duration ◽  
Cross Sectional ◽  
Elderly Individuals ◽  
Short Sleep ◽  
Long Sleep ◽  
Good Sleep

The main purpose of the study was to explore the associations of sleep duration and sleep quality with physical activity (PA). In this cross-sectional study, participants were 894 elderly individuals (mean age 80 ± 3 years; 56.0% women) living in nursing homes. PA, sleep duration, and sleep quality (based on the Pittsburgh Sleep Quality Index (PSQI)) were self-reported. The associations of sleep duration and sleep quality with PA at the nursing home level were analyzed using generalized estimating equations with clustering. Participants reporting short sleep duration (<6 h; OR = 0.45; 95% CI 0.25–0.80) were less likely to report sufficient PA, yet those reporting long sleep duration (>9 h; OR = 2.61; 95% CI 1.35–5.02) and good sleep quality (<5 points; OR = 1.59; 95% CI 1.19–2.12) were more likely to report sufficient PA. When sleep duration and sleep quality were entered into the same model, the same associations remained. This study shows that elderly individuals who report short sleep duration are less likely to meet PA guidelines, while those who report long sleep duration and good sleep quality are more likely to meet PA guidelines. Strategies aiming to improve sleep duration and sleep quality are warranted.

scholarly journals Association between Sleep Duration and Measurable Cardiometabolic Risk Factors in Healthy Korean Women: The Fourth and Fifth Korean National Health and Nutrition Examination Surveys (KNHANES IV and V)

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Hyeyeon Min ◽  
Yoo Jin Um ◽  
Bum Sup Jang ◽  
Doosup Shin ◽  
EunJoo Choi ◽  
...  
Keyword(s):  
Sleep Duration ◽  
Abdominal Obesity ◽  
National Health ◽  
Multivariate Logistic Regression Analysis ◽  
Korean Women ◽  
Short Sleep Duration ◽  
Cross Sectional ◽  
Short Sleep ◽  
Health And Nutrition ◽  
Long Sleep

Study Objectives.To examine the association between sleep duration and prevalence of metabolic syndrome (MetS) and its components in healthy Korean women.Design.Cross-sectional study, using the Fourth and Fifth Korean National Health and Nutrition Examination Surveys.Methods.Among 8505 women (25–70 years) from KNHANES IV and V, participants were classified into five sleep groups based on self-reported sleep duration. MetS and its components were defined using the criteria set forth in National Cholesterol Education Program-Adult Treatment Panel III. We used multivariate logistic regression analysis.Results.After adjusting for various confounders, shorter sleep duration (≤6 h) was found to have an association with low risk of reduced high-density lipoprotein cholesterol and increased triglycerides, whereas very long sleep duration was found to have high risk of increased triglycerides. However, abdominal obesity showed an opposite trend: short sleep duration was associated with higher risk of abdominal obesity than long sleep duration. Fasting glucose levels increased as sleep duration increased, but without significance. Moreover, blood pressure was not significantly associated with sleep duration. Consequently, MetS was less prevalent in those with short sleep duration.Conclusions.Sleep duration was positively associated with MetS, especially dyslipidemia and fasting hyperglycemia, but inversely associated with abdominal obesity.

scholarly journals Cross-Sectional Associations of Physical Fitness Performance Level and Sleep Duration among Older Adults: Results from the National Physical Fitness Survey in Taiwan

2020 ◽  
Vol 17 (2) ◽  
pp. 388 ◽  
Author(s):  
Lee ◽  
Ho ◽  
Yeh ◽  
Hung ◽  
Chang ◽  
...  
Keyword(s):  
Older Adults ◽  
Physical Fitness ◽  
Sleep Duration ◽  
Step Test ◽  
Short Sleep Duration ◽  
Cross Sectional ◽  
Chair Stand ◽  
Short Sleep ◽  
The Third ◽  
Long Sleep

Research on relationships between physical fitness and sleep duration among older adults is scarce, especially in Taiwanese representative samples of elderly people who undergo physical fitness measurements. This study aimed to determine the associations between physical fitness and short and long sleep durations among older adults in Taiwan. We conducted a cross-sectional study and reviewed data derived from the National Physical Fitness Survey in Taiwan. A total of 24,125 Taiwanese adults aged 65 years and older participated in this study between October 2014 and March 2015. Each individual’s sleep duration was recorded with a standard questionnaire method. Sleep duration data were stratified into short (≤5 h), normal (6–7 h), and long (≥8 h) sleep duration groups. Physical fitness was assessed by five components: aerobic endurance (2 min step test), muscle strength and endurance (30 s arm curl and 30 s chair stand tests), flexibility (back scratch and chair sit-and-reach tests), body composition (body mass index (BMI) and waist-to-hip ratio (WHR)), and balance (one-leg stance with eye open and 8-foot up-and-go tests). To understand whether a dose–response relationship exists between physical fitness and short or long sleep duration, we analyzed four levels of performance on the basis of quartiles of physical fitness measurements by using logistic regression. The first quartile of physical fitness performance was the baseline level. The odds ratio (OR) for short sleep duration for the third quartile of BMI was 0.8031 times (95% CI, 0.7119–0.9061) lower than the baseline. For the fourth quartile of BMI, the OR was 0.8660 times (95% CI, 0.7653–0.9800) lower than the baseline. The adjusted OR for long sleep duration significantly decreased in the second, third, and fourth quartiles of the 30 s chair stand, back scratch, chair sit-and-reach test, one-leg stance with one eye open, and BMI. The adjusted OR was increased in the third and fourth quartiles of the 8-foot up-and-go and WHR. The results of the current study suggest that physical fitness performance may influence sleep duration as an associated factor, and the relationship is much stronger for long sleep duration than for short sleep duration.

Causal associations of short and long sleep durations with 12 cardiovascular diseases: linear and nonlinear Mendelian randomization analyses in UK Biobank

2021 ◽  
Author(s):  
Sizhi Ai ◽  
Jihui Zhang ◽  
Guoan Zhao ◽  
Ningjian Wang ◽  
Guohua Li ◽  
...  
Keyword(s):  
Heart Disease ◽  
Arterial Hypertension ◽  
Ischaemic Heart Disease ◽  
Sleep Duration ◽  
Mendelian Randomization ◽  
Short Sleep Duration ◽  
Short Sleep ◽  
Causal Risk Factor ◽  
Long Sleep ◽  
Artery Disease

Abstract Aims Observational studies have suggested strong associations between sleep duration and many cardiovascular diseases (CVDs), but causal inferences have not been confirmed. We aimed to determine the causal associations between genetically predicted sleep duration and 12 CVDs using both linear and nonlinear Mendelian randomization (MR) designs. Methods and results Genetic variants associated with continuous, short (≤6 h) and long (≥9 h) sleep durations were used to examine the causal associations with 12 CVDs among 404 044 UK Biobank participants of White British ancestry. Linear MR analyses showed that genetically predicted sleep duration was negatively associated with arterial hypertension, atrial fibrillation, pulmonary embolism, and chronic ischaemic heart disease after correcting for multiple tests (P &lt; 0.001). Nonlinear MR analyses demonstrated nonlinearity (L-shaped associations) between genetically predicted sleep duration and four CVDs, including arterial hypertension, chronic ischaemic heart disease, coronary artery disease, and myocardial infarction. Complementary analyses provided confirmative evidence of the adverse effects of genetically predicted short sleep duration on the risks of 5 out of the 12 CVDs, including arterial hypertension, pulmonary embolism, coronary artery disease, myocardial infarction, and chronic ischaemic heart disease (P &lt; 0.001), and suggestive evidence for atrial fibrillation (P &lt; 0.05). However, genetically predicted long sleep duration was not associated with any CVD. Conclusion This study suggests that genetically predicted short sleep duration is a potential causal risk factor of several CVDs, while genetically predicted long sleep duration is unlikely to be a causal risk factor for most CVDs.

Abstract P108: Habitual Short Sleep Duration Associated with Self-Reported and Objectively-Determined Cardiovascular and Metabolic Disease Risk Factors: Data from NHANES

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Michael A Grandner ◽  
Subhajit Chakravorty ◽  
Michael Perlis ◽  
Linden Oliver ◽  
Indira Gurubhagavatula
Keyword(s):  
Food Security ◽  
Sleep Duration ◽  
Home Ownership ◽  
Elevated Risk ◽  
Outcome Variable ◽  
Cardiometabolic Health ◽  
Short Sleep Duration ◽  
Short Sleep ◽  
Long Sleep ◽  
Race Ethnicity

Background: Self-reported short and long sleep duration have been associated with adverse cardiometabolic health outcomes in laboratory and epidemiologic studies, but interpretation of such data has been limited by methodological issues. Methods: We analyzed adult 2007-2008 US National Health and Nutrition Examination Survey (NHANES) data (N=5,649). Average self-reported nightly sleep duration was reported and categorized as either very short (<5h), short (5-6h), normal (7-8h), or long (≥9h). Self-reported as well as objective evidence of obesity, diabetes, hypertension, and hyperlipidemia were recorded. Univariate comparisons were conducted across sleep duration categories for all variables. Binary logistic regression analyses were performed using cardiometabolic factor as the outcome variable, and sleep duration category as the predictor variable, before and after adjusting for age, sex, race/ethnicity, acculturation, education, access to insurance, food security, home ownership, smoking, and caffeine use. Results: See table. In adjusted analyses, very short sleep was associated with self-reported hypertension, self-reported hyperlipidemia, objective hyperlipidemia, self-reported diabetes, and objective obesity. Regarding short sleep (5-6hrs), in adjusted analyses, elevated risk was seen for self-reported hypertension self-reported obesity and objective obesity. Regarding long sleep (≥9hrs), no elevated risk was found for any outcomes. Conclusions: Very short and short sleep duration are associated with self-reported and objectively-determined adverse cardiometabolic outcomes, even after adjustment for covariates. Table 1. Unadjusted and Adjusted Odds Ratios (OR) and 95% Confidence Intervals (95%CI) of Associations between Sleep Duration and Cardiometabolic Disease Outcomes *Adjusted analyses include age, sex, race/ethnicity, acculturation, education, insurance, home ownership, food security, smoking, and caffeine

scholarly journals Is sleep duration associated with self-reported overall health, screen time, and nighttime texting among adolescents?

2019 ◽  
Vol 48 (3) ◽  
pp. 030006051989239
Author(s):  
Pernilla Garmy ◽  
Therese Idecrans ◽  
Malin Hertz ◽  
Ann-Christin Sollerhed ◽  
Peter Hagell
Keyword(s):  
Sleep Duration ◽  
Screen Time ◽  
School Health ◽  
Cross Sectional Survey ◽  
Short Sleep Duration ◽  
Cross Sectional ◽  
Short Sleep ◽  
School Day ◽  
Reported Health ◽  
Health Screen

Objectives We aimed to investigate whether sleep duration is associated with self-reported overall health, screen time, and nighttime texting among Swedish adolescents. Methods This was a cross-sectional survey of students (n = 1518) aged 13 to 15 years (50.7% girls) in southern Sweden. Results Fewer than 8 hours sleep duration before a school day was reported by 31% of students. The median time spent watching television and/or at the computer was 3 hours, and 43% of students reported texting at night one or more times per week. Sleeping fewer than 8 hours was significantly associated with poorer self-reported overall health, often being tired at school, increased screen time, and a habit of nighttime texting. Conclusions Short sleep duration (<8 hours) was associated with poor self-reported health, increased screen time, and nighttime texting among respondents. These results provide information for parents, educators, and school health professionals to encourage young people to adopt healthy screen habits and sleep hygiene.

Long and short sleep duration and psychotic symptoms in adolescents: Findings from a cross-sectional survey of 15 786 Japanese students

2020 ◽  
Vol 293 ◽  
pp. 113440
Author(s):  
Ryo Morishima ◽  
Syudo Yamasaki ◽  
Shuntaro Ando ◽  
Shinji Shimodera ◽  
Yasutaka Ojio ◽  
...  
Keyword(s):  
Sleep Duration ◽  
Psychotic Symptoms ◽  
Cross Sectional Survey ◽  
Short Sleep Duration ◽  
Cross Sectional ◽  
Japanese Students ◽  
Short Sleep
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