scholarly journals 0325 Better Aerobic Fitness is Associated with Distinct Sleep Characteristics in Children and Adolescents - A Pilot Study

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A123-A124
Author(s):  
A B Neikrug ◽  
S Radom-Aizik ◽  
I Y Chen ◽  
A Stehli ◽  
K K Lui ◽  
...  
Keyword(s):  
Pilot Study ◽  
Sleep Quality ◽  
Children And Adolescents ◽  
Aerobic Fitness ◽  
Time Consistency ◽  
Sleep Time ◽  
Brain Maturation ◽  
Circadian Activity ◽  
Sleep Patterns ◽  
Local Sleep

Abstract Introduction Aerobic fitness facilitates brain synaptic plasticity, which influences global and local sleep expression. While it is known that sleep patterns/behavior and non-rapid eye movement (NREM) sleep slow wave activity (SWA) tracks brain maturation, little is known about how aerobic fitness and sleep interact during growth and development in children and adolescents. The aim of this pilot study was to characterize relationships among aerobic fitness, measures of global/local sleep expression, and habitual sleep patterns in children and adolescents. We hypothesized that greater aerobic fitness would be associated with better sleep quality, indicated by increased SWA. Methods Twenty healthy youth (11-17 years-old, 11 female) were evaluated during summer vacation (no school schedule constraints). Aerobic fitness (VO2peak) was measured using ramp-type progressive cycle ergometry, habitual sleep (i.e., sleep-time consistency and circadian activity patterns) was assessed with 7-day actigraphy, and ad lib sleep was evaluated during overnight polysomnography (PSG) with high-density electroencephalography (hdEEG; 128 channels). Spectral analysis was implemented to quantify SWA (0.5-4.5Hz). Data were analyzed using linear regression analyses and exploratory independent samples t-tests. Results Negative correlations were observed between VO2peak and sleep measures including sleep-time consistency (partial r=-0.53, p=0.045) and timing/acrophase of the circadian activity rhythm (partial r=-0.64, p=0.01) while controlling for sex and age. Additionally, after accounting for Tanner stage and sex, data demonstrated significant effects in SWA at frontal derivations (p=0.024) between low and high fitness levels at topographically specific and meaningful EEG derivations, e.g. over frontal cortex. Conclusion These results suggest that children and adolescents with greater fitness have less variability in sleep-times (improved sleep consistency), tend to have a more advanced circadian activity phase (i.e., go to sleep earlier), and express greater frontal SWA, supporting the hypothesis that fitness is associated with improved local and global sleep quality. Future research with larger samples is necessary to further evaluate these relationships, and to determine if interventions that improve fitness also improve sleep and related brain plasticity. Support NCATS grant #UL1TR001414 & PERC Systems Biology Fund

146 Better Aerobic Fitness Is Associated with Distinct Sleep Characteristics in Adolescents

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A60-A60
Author(s):  
Ariel Neikrug ◽  
Shlomit Radom-Aizik ◽  
Ivy Chen ◽  
Annamarie Stehli ◽  
Kitty Lui ◽  
...  
Keyword(s):  
Eye Movement ◽  
Slow Wave ◽  
Aerobic Fitness ◽  
Nrem Sleep ◽  
Brain Maturation ◽  
Rapid Eye Movement ◽  
Sleep Spindle ◽  
Sleep Patterns ◽  
Peak Vo2 ◽  
Local Sleep

Abstract Introduction Aerobic fitness facilitates brain synaptic plasticity, which influences global and local sleep expression. While it is known that sleep patterns/behavior and non-rapid eye movement (NREM) sleep slow wave activity (SWA) tracks brain maturation, little is known about how aerobic fitness and sleep interact during development in youth. The aim of this pilot was to characterize relationships among aerobic fitness, measures of global/local sleep expression, and habitual sleep patterns in children and adolescents. We hypothesized that greater aerobic fitness would be associated with better sleep quality, indicated by increased SWA. Methods 20 adolescents (mean age=14.6±2.3 years old, range 11-17, 11 females) were evaluated for AF (peak VO2 assessed by ramp-type progressive cycle ergometry in the laboratory), habitual sleep duration and efficiency (continuous 7-14 day actigraphy with sleep diary), and topographic patterns of spectral power in slow wave, theta, and sleep spindle frequency ranges in non-rapid eye movement (NREM) sleep using overnight polysomnography with high-density electroencephalography (hdEEG, 128 channels). Results Significant relationships were observed between peak VO2 and habitual bedtime (r=-0.604, p=0.013) and wake-up time (r=-0.644, p=0.007), with greater fitness associated with an earlier sleep schedule (going to bed and waking up earlier). Peak VO2 was a significant predictor of slow oscillations (0.5-1Hz, p=0.018) and theta activity (4.5-7.5Hz, p=0.002) over anterior frontal and central derivations (p<0.001 and p=0.001, respectively) after adjusting for sex and pubertal development stage. Similar associations were detected for fast sleep spindle activity (13-16Hz, p=0.006), which was greater over temporo-parietal derivations. Conclusion Greater AF was associated with earlier habitual sleep times and with enhanced expression of developmentally-relevant sleep oscillations during NREM sleep. These data suggest that AF may 1) minimize the behavioral sleep delay commonly seen during adolescence, and 2) impact topographically-specific features of sleep physiology known to mechanistically support neuroplasticity and cognitive processes which are dependent on prefrontal cortex and hippocampal function in adolescents and adults. Support (if any) NCATS grant #UL1TR001414 & PERC Systems Biology Fund

145 Aerobic Fitness Is Associated with Advanced Circadian Rhythms in Adolescents

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A59-A60
Author(s):  
Ariel Neikrug ◽  
Shlomit Radom-Aizik ◽  
Ivy Chen ◽  
Annamarie Stehli ◽  
Kitty Lui ◽  
...  
Keyword(s):  
Eye Movement ◽  
Slow Wave ◽  
Aerobic Fitness ◽  
Nrem Sleep ◽  
Brain Maturation ◽  
Rapid Eye Movement ◽  
Sleep Spindle ◽  
Sleep Patterns ◽  
Peak Vo2 ◽  
Local Sleep

Abstract Introduction Aerobic fitness facilitates brain synaptic plasticity, which influences global and local sleep expression. While it is known that sleep patterns/behavior and non-rapid eye movement (NREM) sleep slow wave activity (SWA) tracks brain maturation, little is known about how aerobic fitness and sleep interact during development in youth. The aim of this pilot was to characterize relationships among aerobic fitness, measures of global/local sleep expression, and habitual sleep patterns in children and adolescents. We hypothesized that greater aerobic fitness would be associated with better sleep quality, indicated by increased SWA. Methods 20 adolescents (mean age=14.6±2.3 years old, range 11-17, 11 females) were evaluated for AF (peak VO2 assessed by ramp-type progressive cycle ergometry in the laboratory), habitual sleep duration and efficiency (continuous 7-14 day actigraphy with sleep diary), and topographic patterns of spectral power in slow wave, theta, and sleep spindle frequency ranges in non-rapid eye movement (NREM) sleep using overnight polysomnography with high-density electroencephalography (hdEEG, 128 channels). Results Significant relationships were observed between peak VO2 and habitual bedtime (r=-0.604, p=0.013) and wake-up time (r=-0.644, p=0.007), with greater fitness associated with an earlier sleep schedule (going to bed and waking up earlier). Peak VO2 was a significant predictor of slow oscillations (0.5-1Hz, p=0.018) and theta activity (4.5-7.5Hz, p=0.002) over anterior frontal and central derivations (p<0.001 and p=0.001, respectively) after adjusting for sex and pubertal development stage. Similar associations were detected for fast sleep spindle activity (13-16Hz, p=0.006), which was greater over temporo-parietal derivations. Conclusion Greater AF was associated with earlier habitual sleep times and with enhanced expression of developmentally-relevant sleep oscillations during NREM sleep. These data suggest that AF may 1) minimize the behavioral sleep delay commonly seen during adolescence, and 2) impact topographically-specific features of sleep physiology known to mechanistically support neuroplasticity and cognitive processes which are dependent on prefrontal cortex and hippocampal function in adolescents and adults. Support (if any) NCATS grant #UL1TR001414 & PERC Systems Biology Fund

scholarly journals Gender differences in BaYaka forager sleep-wake patterns in forest and village contexts

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Erica Kilius ◽  
David R. Samson ◽  
Sheina Lew-Levy ◽  
Mallika S. Sarma ◽  
Ujas A. Patel ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Total Sleep Time ◽  
Sleep Time ◽  
Small Scale ◽  
Cultural Variation ◽  
Sleep Patterns ◽  
Economic Activities ◽  
Mixed Effect ◽  
Wake Patterns ◽  
The Republic

AbstractSleep studies in small-scale subsistence societies have broadened our understanding of cross-cultural sleep patterns, revealing the flexibility of human sleep. We examined sleep biology among BaYaka foragers from the Republic of Congo who move between environmentally similar but socio-ecologically distinct locations to access seasonal resources. We analyzed the sleep–wake patterns of 51 individuals as they resided in a village location (n = 39) and a forest camp (n = 23) (362 nights total). Overall, BaYaka exhibited high sleep fragmentation (50.5) and short total sleep time (5.94 h), suggestive of segmented sleep patterns. Sleep duration did not differ between locations, although poorer sleep quality was exhibited in the village. Linear mixed effect models demonstrated that women’s sleep differed significantly from men’s in the forest, with longer total sleep time (β ± SE =  − 0.22 ± 0.09, confidence interval (CI) = [− 0.4, − 0.03]), and higher sleep quality (efficiency; β ± SE =  − 0.24 ± 0.09, CI = [− 0.42, − 0.05]). These findings may be due to gender-specific social and economic activities. Circadian rhythms were consistent between locations, with women exhibiting stronger circadian stability. We highlight the importance of considering intra-cultural variation in sleep–wake patterns when taking sleep research into the field.

scholarly journals The Travel Demands of an Elite Rugby Sevens Team: Effects on Objective and Subjective Sleep Parameters

2021 ◽  
Vol 16 (5) ◽  
pp. 688-694
Author(s):  
Cédric Leduc ◽  
Julien Robineau ◽  
Jason C. Tee ◽  
Jeremy Cheradame ◽  
Ben Jones ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Mixed Models ◽  
Total Sleep Time ◽  
Sleep Time ◽  
Jet Lag ◽  
Sleep Patterns ◽  
Subjective Sleep ◽  
World Series ◽  
Sleep Parameters ◽  
The Difference

Purpose: To explore the effects of travel related to international rugby sevens competition on sleep patterns. Methods: A total of 17 international male rugby sevens players participated in this study. Actigraphic and subjective sleep assessments were performed daily during 2 separate Sevens World Series competition legs (Oceania and America). The duration of each competition leg was subdivided into key periods (pretour, precompetition, tournament 1, relocation, tournament 2, and posttour) lasting 2 to 7 nights. Linear mixed models in combination with magnitude-based decisions were used to assess (1) the difference between preseason and key periods and (2) the effect of travel direction (eastward or westward). Results: Shorter total sleep time (hours:minutes) was observed during tournament 2 (mean [SD], 06:16 [01:08]), relocation (06:09 [01:09]), and the pretour week (06:34 [01:24]) compared with the preseason (06:52 [01:00]). Worse sleep quality (arbitrary units) was observed during tournament 1 (6.1 [2.0]) and 2 (5.7 [1.2]), as well as during the relocation week (6.3 [1.5]) than during the preseason (6.5 [1.8]). When traveling eastward compared with westward, earlier fall-asleep time was observed during tournament 1 (ES − 0.57; 90% CI, −1.12 to −0.01), the relocation week (−0.70 [−1.11 to −0.28]), and the posttour (−0.57 [−0.95 to −0.18]). However, possibly trivial and unclear differences were observed during the precompetition week (0.15 [−0.15 to 0.45]) and tournament 2 (0.81 [−0.29 to 1.91]). Conclusion: The sleep patterns of elite rugby sevens players are robust to the effects of long-haul travel and jet lag. However, the staff should consider promoting sleep during the tournament and relocation week.

Comparison of Continuous versus Intermittent Administration of Zolpidem in Chronic Insomniacs: A Double-Blind, Randomized Pilot Study

1998 ◽  
Vol 26 (1) ◽  
pp. 13-24 ◽  
Author(s):  
R Cluydts ◽  
K Peeters ◽  
I de Bouyalsky ◽  
J Lavoisy
Keyword(s):  
Pilot Study ◽  
Adverse Events ◽  
Sleep Quality ◽  
Total Sleep Time ◽  
Sleep Time ◽  
Chronic Insomnia ◽  
Global Evaluation ◽  
Efficacy And Safety ◽  
Double Blind ◽  
Intermittent Administration

The subjective efficacy and safety of intermittent administration of a hypnotic for insomnia was assessed, since such a regime may provide a potential means of reducing the risk of habituation and dependence. A total of 160 adult patients (mean 45 years) with chronic insomnia were treated for 2 weeks with zolpidem, 10 mg, either continuously or intermittently (five nights zolpidem, two consecutive nights placebo per week) in this multicentre, out-patient, pilot study. At the end of the 2-week treatment, patients subjectively estimated their nightly total sleep time as 6.96 ± 1.19 h (from 6.07 ± 1.25 h at baseline) and 6.94 ± 1.30 h (from 5.72 ± 1.46 h) after the continuous and intermittent treatments, respectively. Patients' reports did not indicate any differences between the two groups in global evaluation of impairment, sleep quality, or the incidence of adverse events. These results suggest that the efficacy and safety of zolpidem, 10 mg, are comparable whether the drug is administered every night or intermittently. Further studies with a broader well-defined patient base, are needed to confirm these data.

scholarly journals Introducing Sleep Hygiene to the Church of Sidang Jemaat Allah Bethlehem Congregation, Bogor, West Java

2021 ◽  
Vol 5 (1) ◽  
pp. 61-70
Author(s):  
Alya Dwiana ◽  
Triyana Sari ◽  
David Limanan
Keyword(s):  
Sleep Quality ◽  
Cognitive Abilities ◽  
Healthy Lifestyle ◽  
Sleep Hygiene ◽  
Sleep Time ◽  
The Body ◽  
Poor Sleep ◽  
Sleep Patterns ◽  
Lack Of Sleep ◽  
The Individual

Insomnia is one of the most common health problems. Approximately one-third of adults show symptoms related to insomnia. Around 9%-15% of people have sleeping disorders dan suffer the consequences of it in the daytime, and roughly 6% suffer from diagnosed insomnia. Although the prevalence and significant effects of insomnia have been known, sleep disorders are still rarely diagnosed and receive proper treatments. Lack of sleep will create sleep debt that the body will have to compensate for by adding more sleep time in the next day. Should this compensation fail to be fulfilled, the individual will suffer from excessive sleepiness, memory problems, difficulty concentrating, and disturbances in performing daily activities. Chronic lack of sleep can also decrease memory and cognitive abilities, trigger mood disorders and even cause hallucination. The Sidang Jemaat Allah Bethlehem church (GSJA) is one of the biggest churches in Bogor. The people of GSJA’s knowledge of healthy sleep patterns and their sleep quality was unknown. Therefore, it was necessary to provide sleep health education to raise the awareness of the importance of healthy sleep patterns, both the quantity and the quality, in practicing a healthy lifestyle. We also assessed their sleep quality using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. The data show that out of 41 participants, 30 of them (73.11%) have poor sleep quality (score ≥ 5) and most of them were in the 71-80-year-old age group. The participants' level of understanding about sleep hygiene has increased after the event.

scholarly journals The Effects of Caffeine on Sleep Patterns Among Adolescents

2009 ◽  
Vol 5 ◽  
Author(s):  
Lauren E Margolis
Keyword(s):  
Sleep Quality ◽  
Total Sleep Time ◽  
Adult Population ◽  
Sleep Onset ◽  
Onset Time ◽  
Sleep Time ◽  
Caffeine Intake ◽  
Sleep Patterns ◽  
Sleep Habits ◽  
Caffeine Consumption

This review of literature examines whether there is a causal relationship between caffeine consumption and sleep patterns among adolescents. Literature suggests that there is a cause and effect relationship between caffeine intake and cognitive performance in adults. Researchers also found that among the adult population, consuming caffeine before sleep resulted in increased sleep onset time, reduced total sleep time, and poorer sleep quality. Specifically, adolescents ingest the majority of their total caffeine intake through caffeinated sodas. Studies have shown that adolescents consume more caffeine later in the week, which correlates with shorter total sleep time and decreased sleep quality. Thus, in review of the literature, it was determined that caffeine negatively affects sleep habits among adults, but further research should be conducted in order to conclude whether this relationship holds true among adolescents.

scholarly journals 0335 Frontal Expression of NREM Sleep Oscillations are Associated with Executive Function in Children and Adolescents

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A127-A127
Author(s):  
K K Lui ◽  
B A Mander ◽  
S Radom-Aizik ◽  
M G Chappel-Farley ◽  
A Dave ◽  
...  
Keyword(s):  
Executive Function ◽  
Brain Development ◽  
Children And Adolescents ◽  
Slow Wave ◽  
Tanner Stage ◽  
Nrem Sleep ◽  
Brain Regions ◽  
Brain Maturation ◽  
Healthy Children ◽  
Local Sleep

Abstract Introduction The prefrontal cortex, an area known for executive functioning (including inhibition and self-monitoring) develops during childhood and adolescents, with a pattern of posterior to anterior brain development. Slow-wave activity (SWA) in NREM sleep, tracks brain development with high SWA power migrating from occipital to frontal region as brain maturation occurs. This pilot study aimed to examine whether slow wave topography is correlated with executive function in youth. Methods Seventeen healthy children and adolescents (ages 11-17; 10 females) underwent overnight polysomnography (PSG) with high-density electroencephalography (hdEEG). Behavior Rating Inventory of Executive Function (BRIEF) was administered to assess executive function. SWA (SWA1: 0.5-1 Hz; SWA2: 1-4.5 Hz) and spindle (slow sigma: 11-13 Hz; fast sigma: 13-16 Hz) activity was analyzed with spectral analysis using Welch’s method. BRIEF subscales of inhibition and monitor were correlated with SWA and sigma power across all derivations, with Holm-Bonferroni correction (126 channels). Significant derivations were then controlled for sex and self-reported Tanner stage using multiple regression Results BRIEF-Inhibition scale (i.e., ability to repress impulsivity) and SWA1 in anterior frontal derivations were negatively correlated (R2=0.58, p=0.047 corrected). BRIEF-Monitor scale (i.e., self-perception of one’s own behavior and interpersonal awareness) was negatively correlated with fast sigma in anterior frontal derivations (R2=0.65, p=0.013 corrected). These associations were significant after controlling for sex and Tanner stage. Conclusion These results support the hypothesis that NREM sleep oscillations are associated with executive function and reflect changes in neuroplasticity related to “back-to-front” brain maturation. Future longitudinal studies should combine multi-modal neuroimaging of brain structure and local sleep with comprehensive assessments of executive function to evaluate the possible link between local sleep and development of higher-order cognition in frontal brain regions in youth. Support NCATS grant #UL1TR001414 & PERC Systems Biology Fund

Sign in / Sign up

Export Citation Format

Share Document