scholarly journals Dexamethasone negative side effects on insulin signaling is prevented by Exercise Training: role of IRS‐1 and p‐AKT

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Thiago José Dionísio ◽  
Juliana Cavalcante Andrade Louzada ◽  
Bruno Alvares Viscelli ◽  
Evandro José Dionísio ◽  
Aline Mio Martuscelli ◽  
...  
2021 ◽  
Vol 10 (7) ◽  
pp. 1388
Author(s):  
Marta Malesza ◽  
Erich Wittmann

The main aim of this study was to investigate the various factors influencing COVID-19 vaccination acceptance and actual intake among older Germans aged over 75 years old (n = 1037). We found that the intention to get vaccinated or intake of the COVID-19 vaccine were positively related to the perceptions of becoming infected, perceptions of the severity of the potential long-term effects, the vaccine’s efficacy, and the benefits of vaccination. Meanwhile, the intention to get the vaccine or vaccine intake were decreased by perceptions of the negative side-effects and the general impediments to vaccination.


2022 ◽  
Author(s):  
health not provided

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2021 ◽  
Author(s):  
hengstla not provided

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Author(s):  
Sandhya Saisubramanian ◽  
Ece Kamar ◽  
Shlomo Zilberstein

Agents operating in unstructured environments often create negative side effects (NSE) that may not be easy to identify at design time. We examine how various forms of human feedback or autonomous exploration can be used to learn a penalty function associated with NSE during system deployment. We formulate the problem of mitigating the impact of NSE as a multi-objective Markov decision process with lexicographic reward preferences and slack. The slack denotes the maximum deviation from an optimal policy with respect to the agent's primary objective allowed in order to mitigate NSE as a secondary objective. Empirical evaluation of our approach shows that the proposed framework can successfully mitigate NSE and that different feedback mechanisms introduce different biases, which influence the identification of NSE.


Author(s):  
Jeanne Gaakeer

In chapter 7 the importance of insight into how metaphor works in law (“seeing resemblance” according to Ricoeur) is elaborated upon in relation to the legal professional’s development of practical wisdom. The chapter discusses how metaphoric insight is both cognitive and perceptual. It argues that the professional needs to develop his or her legal imagination to be able to perceive similarity in what is initially thought of as dissimilarity to bridge the gap between the generality of the legal rule and the particularity of the individual situation in the case at hand. The chapter also connects the topic of metaphor to an understanding the psychological phenomenon of cognitive dissonance and its negative side-effects such as the confirmation bias and belief perseverance as the obverse phenomena of what Coleridge called poetic faith, i.e. the ability to comprehend contraries and to deal with uncertainties before jumping to conclusions.


Author(s):  
Filipe Teles ◽  
Pekka Kettunen

It is a common phenomenon that municipalities cooperate with each other. Cooperation eventually brings about the gains of efficiency or makes it possible to deliver services. We can however assume that cooperation may also fail, cause unwarranted negative side-effects and diminish the democratic capacity of the participating municipalities. The aim of this paper is to present the literature and available scholarship on the topic, and discuss the research agenda on inter-municipal cooperation, especially through the analysis of its scope, motivations, and perceived costs and benefits. The approach to the problem will be based in multidisciplinary contributions of existing research, which involves theoretical arguments related to the advantages of cooperation, the impact on democracy and accountability, as well as the discussion of public vs private provision of services. The conclusions should enable a serious reflection about Inter-Municipal Cooperation state of the art.


2019 ◽  
pp. 993-1040
Author(s):  
David Semple ◽  
Roger Smyth

This chapter covers therapeutic issues in psychiatry, from medication adherence, off-label prescribing and associated legal considerations, negative side effects such as weight gain and sexual dysfunction in different forms of psychiatric medicines, potential interactions or contraindications for prescribing, and specific side effects. Special prescribing cases, such as psychiatric medicine in pregnancy and breastfeeding patients or those with heart, liver, or kidney disease, are explained.


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