scholarly journals Effects of a novel dietary supplement on physical and mental function in middle‐aged adults: a double‐blind, randomized, placebo‐controlled trial

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Steven M Wood ◽  
Steve Poole ◽  
Mark Bartlett ◽  
Angela Mastaloudis ◽  
Doug Burke
Keyword(s):  
Dietary Supplement ◽  
Controlled Trial ◽  
Mental Function ◽  
Middle Aged ◽  
Double Blind ◽  
Middle Aged Adults

scholarly journals The Influence of Tart Cherry (Prunus cerasus, cv Montmorency) Concentrate Supplementation for 3 Months on Cardiometabolic Risk Factors in Middle-Aged Adults: A Randomised, Placebo-Controlled Trial

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1417
Author(s):  
Rachel Kimble ◽  
Karen M. Keane ◽  
John K. Lodge ◽  
Glyn Howatson
Keyword(s):  
Vascular Function ◽  
Controlled Trial ◽  
High Sensitivity ◽  
Metabolic Health ◽  
Cardiometabolic Health ◽  
Middle Aged ◽  
Concentrate Supplementation ◽  
Health Indices ◽  
Before And After ◽  
Middle Aged Adults

Background: Tart Montmorency cherries (MC) have been shown to be rich in anthocyanins and other phytochemicals known to have anti-inflammatory properties and influence pathways that might improve cardiometabolic health. However, there is limited evidence for the longer-term use of tart cherries on these indices. The aim of the current study was to investigate the influence of MC concentrate on cardiometabolic health indices following a 3-month supplementation period. Methods: Fifty middle-aged adults (34 males and 16 females; mean ± SD age: 48 ± 6 years and BMI: 27.6 ± 3.7 kg/m2) completed a randomised, placebo-controlled parallel study in which they either received MC or an isocaloric placebo. Participants drank 30 mL of their allocated treatment twice per day for 3 months. Vascular function (blood pressure [BP], heart rate [HR], pulse wave velocity and analysis [PWV/A], and flow mediated dilation [FMD]) as well as indices of metabolic health (insulin, glucose, lipid profiles, and high sensitivity C reactive protein) were measured following an overnight fast before and after the 3 months. Results: No effect of the intervention between the groups was observed for vascular function or metabolic health variables following the intervention (p > 0.05). However, MC concentrate was shown to be safe and well-tolerated and, importantly, did not have any deleterious effects on these outcomes. In conclusion, MC has no influence on cardiometabolic indices in middle-aged adults.

scholarly journals Treatment of climacteric symptoms with an ammonium succinate-based dietary supplement: a randomized, double-blind, placebo-controlled trial

2016 ◽  
Vol 32 (sup2) ◽  
pp. 64-68 ◽  
Author(s):  
V. E. Radzinskii ◽  
I. V. Kuznetsova ◽  
Y. B. Uspenskaya ◽  
N. B. Repina ◽  
Y. K. Gusak ◽  
...  
Keyword(s):  
Dietary Supplement ◽  
Controlled Trial ◽  
Climacteric Symptoms ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Ammonium Succinate

scholarly journals Improved balance in middle-aged adults after 8 weeks of a modified version of Otago Exercise Program: A randomized controlled trial

PLoS ONE ◽  
2020 ◽  
Vol 15 (7) ◽  
pp. e0235734
Author(s):  
Rana Almarzouki ◽  
Gurinder Bains ◽  
Everett Lohman ◽  
Bruce Bradley ◽  
Todd Nelson ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Exercise Program ◽  
Middle Aged ◽  
Randomized Controlled ◽  
Middle Aged Adults

scholarly journals Leucine-Enriched Protein Supplementation Increases Lean Body Mass in Healthy Korean Adults Aged 50 Years and Older: A Randomized, Double-Blind, Placebo-Controlled Trial

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1816
Author(s):  
Yeji Kang ◽  
Namhee Kim ◽  
Yong Jun Choi ◽  
Yunhwan Lee ◽  
Jihye Yun ◽  
...  
Keyword(s):  
Lean Body Mass ◽  
Body Mass ◽  
Controlled Trial ◽  
Intervention Group ◽  
Dropout Rate ◽  
Protein Supplementation ◽  
Community Dwelling ◽  
Control Group ◽  
Middle Aged ◽  
Middle Aged Adults

Early prevention of sarcopenia could be an important strategy for muscle retention, but most studies have focused on subjects aged 65 or older. Therefore, in this study we investigated the effects of leucine-enriched protein supplementation on muscle condition in a sample including late middle-aged adults. A 12-week intervention was performed for 120 healthy community-dwelling adults by providing either leucine-enriched protein supplement [protein 20g(casein 50%+ whey 40%+ soy 10%, total leucine 3000 mg), vitamin D 800IU(20 ug), calcium 300 mg, fat 1.1 g, carbohydrate 2.5 g] or isocaloric carbohydrate supplement twice per day. Appendicular skeletal muscle mass (ASM) and lean body mass (LBM) were measured by dual-energy X-ray absorptiometry. A total of 111 participants completed the study, with a dropout rate of 9.2%. LBM normalized by body weight (LBM/Wt) was significantly increased (p < 0.001) in the intervention group (0 wk: 63.38 ± 0.85 vs. 12 wk 63.68 ± 0.83 in the intervention group; 0 wk: 63.85 ± 0.82 vs. 12 wk: 63.29 ± 0.81 in the control group). In subgroup analyses, significant differences remained only in subjects between 50 and 64 years of age. We concluded that leucine-enriched protein supplementation can have beneficial effects by preventing muscle loss, mainly for late middle-aged adults.

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