EFFECT OF MODERATE INTENSITY ENDURANCE TRAINING ON RAT HEART METABOLISM

1998 ◽  
Vol 30 (Supplement) ◽  
pp. 16
Author(s):  
M. L. Zonderland ◽  
P. R. B??r ◽  
J. C. Reijneveld ◽  
B. M. Spruijt ◽  
H. A. Keizer ◽  
...  
Biomolecules ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 498
Author(s):  
Mojdeh Khajehlandi ◽  
Lotfali Bolboli ◽  
Marefat Siahkuhian ◽  
Mohammad Rami ◽  
Mohammadreza Tabandeh ◽  
...  

Exercise can ameliorate cardiovascular dysfunctions in the diabetes condition, but its precise molecular mechanisms have not been entirely understood. The aim of the present study was to determine the impact of endurance training on expression of angiogenesis-related genes in cardiac tissue of diabetic rats. Thirty adults male Wistar rats were randomly divided into three groups (N = 10) including diabetic training (DT), sedentary diabetes (SD), and sedentary healthy (SH), in which diabetes was induced by a single dose of streptozotocin (50 mg/kg). Endurance training (ET) with moderate-intensity was performed on a motorized treadmill for six weeks. Training duration and treadmill speed were increased during five weeks, but they were kept constant at the final week, and slope was zero at all stages. Real-time polymerase chain reaction (RT-PCR) analysis was used to measure the expression of myocyte enhancer factor-2C (MEF2C), histone deacetylase-4 (HDAC4) and Calmodulin-dependent protein kinase II (CaMKII) in cardiac tissues of the rats. Our results demonstrated that six weeks of ET increased gene expression of MEF2C significantly (p < 0.05), and caused a significant reduction in HDAC4 and CaMKII gene expression in the DT rats compared to the SD rats (p < 0.05). We concluded that moderate-intensity ET could play a critical role in ameliorating cardiovascular dysfunction in a diabetes condition by regulating the expression of some angiogenesis-related genes in cardiac tissues.


Author(s):  
Mustafa Gul ◽  
Berna Demircan ◽  
Seyithan Taysi ◽  
Nuray Oztasan ◽  
Kenan Gumustekin ◽  
...  

2002 ◽  
Vol 17 (1) ◽  
pp. 33-41 ◽  
Author(s):  
Bronwen Ackermann ◽  
Roger Adams ◽  
Elfreda Marshall

The purposes of this study were to evaluate the effect of an exercise regimen for undergraduate music majors at a university, and to determine whether a short-term, moderate-intensity program designed to assist in their preparation for the athletic task of playing an instrument for many hours a day could be incorporated into their timetables and show strength gains. In this study, 18 volunteer university undergraduate music majors were randomly allocated into either six weeks of strength training or six weeks of endurance training of proximal upper-limb and trunk muscles. All subjects were measured over a six-week control period prior to the exercise period. Tests using both physical and self-report data were repeated on three separate occasions to determine whether training produced any effects over this period, and which form of training was the more effective. Physical testing data were collected by an independent tester who was blinded to the study condition. These data included Cybex dynamometer testing in two planes of shoulder motion, field measurements, and timing an isometric 90-degree forward flexion arm hold. Questionnaires were used to gather data on the frequency and severity of performance-related musculoskeletal disorders and on the perceived exertion of playing. Results indicated that the program produced significant strength gains in both field measurements and dynamometer testing in both exercise groups. While all field measurements of the actual exercises performed increased significantly over the exercise period, the dynamometer results showed a significant effect of the exercise program on the horizontal plane only, suggesting this group of musicians took a task-specific view of the exercises and focused more on their application of horizontal exercises, seeing the relevance in relation to playing an instrument. Vertical isokinetic measurements remained unchanged. Perceived exertion of playing was significantly reduced, with endurance training significantly better than strength training for achieving this result.


Author(s):  
Øyvind Sandbakk ◽  
Thomas Haugen ◽  
Gertjan Ettema

Purpose: To provide novel insight regarding the influence of exercise modality on training load management by (1) providing a theoretical framework for the impact of physiological and biomechanical mechanisms associated with different exercise modalities on training load management in endurance exercise and (2) comparing effort-matched low-intensity training sessions performed by top-level athletes in endurance sports with similar energy demands. Practical Applications and Conclusions: The ability to perform endurance training with manageable muscular loads and low injury risks in different exercise modalities is influenced both by mechanical factors and by muscular state and coordination, which interrelate in optimizing power production while reducing friction and/or drag. Consequently, the choice of exercise modality in endurance training influences effort beyond commonly used external and internal load measurements and should be considered alongside duration, frequency, and intensity when managing training load. By comparing effort-matched low- to moderate-intensity sessions performed by top-level athletes in endurance sports, this study exemplifies how endurance exercise with varying modalities leads to different tolerable volumes. For example, the weight-bearing exercise and high-impact forces in long-distance running put high loads on muscles and tendons, leading to relatively low training volume tolerance. In speed skating, the flexed knee and hip position required for effective speed skating leads to occlusion of thighs and low volume tolerance. In contrast, the non-weight-bearing, low-contraction exercises in cycling or swimming allow for large volumes in the specific exercise modalities. Overall, these differences have major implications on training load management in sports.


1994 ◽  
Vol 76 (6) ◽  
pp. 2253-2261 ◽  
Author(s):  
G. A. Brooks ◽  
J. Mercier

The “crossover” concept represents a theoretical means by which one can understand the effects of exercise intensity and prior endurance training on the balance of carbohydrate (CHO) and lipid metabolism during sustained exercise. According to the crossover concept, endurance training results in muscular biochemical adaptations that enhance lipid oxidation as well as decrease the sympathetic nervous system responses to given submaximal exercise stresses. These adaptations promote lipid oxidation during mild- to moderate-intensity exercise. In contrast, increases in exercise intensity are conceived to increase contraction-induced muscle glycogenolysis, alter the pattern of fiber type recruitment, and increase sympathetic nervous system activity. Therefore the pattern of substrate utilization in an individual at any point in time depends on the interaction between exercise intensity-induced responses (which increase CHO utilization) and endurance training-induced responses (which promote lipid oxidation). The crossover point is the power output at which energy from CHO-derived fuels predominates over energy from lipids, with further increases in power eliciting a relative increment in CHO utilization and a decrement in lipid oxidation. The contemporary literature contains data indicating that, after endurance training, exercise at low intensities (< or = 45% maximal O2 uptake) is accomplished with lipid as the main substrate. In contrast, the literature also contains reports that are interpreted to indicate that during hard-intensity exercise (approximately 75% maximal O2 uptake) CHO is the predominant substrate. Seen within the context of the crossover concept these apparently divergent results are, in fact, consistent.(ABSTRACT TRUNCATED AT 250 WORDS)


1973 ◽  
Vol 51 (3) ◽  
pp. 234-238 ◽  
Author(s):  
Naranjan S. Dhalla ◽  
John C. Yates ◽  
Israel Kleinberg

The intramuscular pH of the isolated perfused rat heart fluctuated between 7.11 and 7.14 during each contraction–relaxation cycle; the pH began to decline prior to the onset of cardiac contraction. The observed pH oscillations are independent of the mechanical activity and seem to reflect cyclic fluctuations in heart metabolism during the process of "excitation – metabolic stimulation" in the cardiac muscle.


2008 ◽  
Vol 14 (1) ◽  
pp. 35-53 ◽  
Author(s):  
U. Dalgas ◽  
E. Stenager ◽  
T. Ingemann-Hansen

This review summarizes the existing knowledge regarding the effects of physical exercise in patients suffering from multiple sclerosis (MS). Furthermore, recommendations are given regarding exercise prescription for MS patients and for future study directions. Previously, MS patients were advised not to participate in physical exercise. During recent years, it has been increasingly acknowledged that exercise benefits MS patients. The requirement for exercise in MS patients is emphasized by their physiological profile, which probably reflects both the effects of the disease per se and the reversible effects of an inactive lifestyle. To date the effects of exercise have only been studied in moderately impaired MS patients with an EDSS score of less than 7. Evidence exists for recommending participation in endurance training at low to moderate intensity, as the existing literature demonstrates that MS patients can both tolerate and benefit from this training modality. Also, resistance training of moderate intensity seems to be well tolerated and to have beneficial effects on MS patients, but the methodological quality of the existing evidence is in general low and the number of studies is limited. Only two studies have evaluated the effects of combined resistance- and endurance training, making solid conclusions regarding this training modality impossible. Multiple Sclerosis 2008; 14: 35—53. http://msj.sagepub.com


2007 ◽  
Vol 39 (Supplement) ◽  
pp. S84-S85
Author(s):  
Inga E. Schjerve ◽  
Gjertrud A. Tyldum ◽  
Arnt E. Tjonna ◽  
Tomas Stolen ◽  
Per M. Haram ◽  
...  

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