Effect of Soy Protein Supplementation on Serum Lipoproteins, Blood Pressure, and Menopausal Symptoms in Perimenopausal Women

Author(s):  
Scott Washburn ◽  
Gregory L. Burke ◽  
Timothy Morgan ◽  
Mary Anthony
2021 ◽  
pp. 1-27
Author(s):  
Masoome Piri Damaghi ◽  
Atieh Mirzababaei ◽  
Sajjad Moradi ◽  
Elnaz Daneshzad ◽  
Atefeh Tavakoli ◽  
...  

Abstract Background: Essential amino acids (EAAs) promote the process of regulating muscle synthesis. Thus, whey protein that contains higher amounts of EAA can have a considerable effect on modifying muscle synthesis. However, there is insufficient evidence regarding the effect of soy and whey protein supplementation on body composition. Thus, we sought to perform a meta-analysis of published Randomized Clinical Trials that examined the effect of whey protein supplementation and soy protein supplementation on body composition (lean body mass, fat mass, body mass and body fat percentage) in adults. Methods: We searched PubMed, Scopus, and Google Scholar, up to August 2020, for all relevant published articles assessing soy protein supplementation and whey protein supplementation on body composition parameters. We included all Randomized Clinical Trials that investigated the effect of whey protein supplementation and soy protein supplementation on body composition in adults. Pooled means and standard deviations (SD) were calculated using random-effects models. Subgroup analysis was applied to discern possible sources of heterogeneity. Results: After excluding non-relevant articles, 10 studies, with 596 participants, remained in this study. We found a significant increase in lean body mass after whey protein supplementation weighted mean difference (WMD: 0.91; 95% CI: 0.15, 1.67. P= 0.019). Subgroup analysis, for whey protein, indicated that there was a significant increase in lean body mass in individuals concomitant to exercise (WMD: 1.24; 95% CI: 0.47, 2.00; P= 0.001). There was a significant increase in lean body mass in individuals who received 12 or less weeks of whey protein (WMD: 1.91; 95% CI: 1.18, 2.63; P<0.0001). We observed no significant change between whey protein supplementation and body mass, fat mass, and body fat percentage. We found no significant change between soy protein supplementation and lean body mass, body mass, fat mass, and body fat percentage. Subgroup analysis for soy protein indicated there was a significant increase in lean body mass in individuals who supplemented for 12 or less weeks with soy protein (WMD: 1.48; 95% CI: 1.07, 1.89; P< 0.0001). Conclusion: Whey protein supplementation significantly improved body composition via increases in lean body mass, without influencing fat mass, body mass, and body fat percentage.


2004 ◽  
Vol 32 (05) ◽  
pp. 755-770 ◽  
Author(s):  
Takahisa Ushiroyama ◽  
Satoshi Yoshida ◽  
Keiichi Tadaki ◽  
Atsushi Ikeda ◽  
Minoru Ueki

To investigate the clinical effects of EH0202, a Japanese herbal supplement, on the menopausal symptoms and physical status of peri- and post-menopausal women. Thirty-two post-menopausal women (53.0±5.1 years) presented with menopausal complaints were enrolled in the clinical study. Patients were administered an herbal supplement, EH0202 (6 g/day for 6 months), and were assessed for improvement of their overall symptoms using the Greene Climacteric Scale and the Visual Analog Scale (VAS). Blood pressure, skin surface blood flow and plasma lipid profiles were measured before and 1, 3 and 6 months after EH0202 administration. There was a significant decrease in the climacteric scale score (P<0.001) and VAS (P<0.0001) after 6 months of EH0202 treatment. There was a significant decrease in systolic (P<0.001) and diastolic (P<0.05) blood pressure, and a significant decrease in facial skin surface blood flow (P<0.05) after 3 months of EH0202 administration. We observed a significant decrease in plasma TG and LDL-cholesterol concentrations after 3 months of EH0202 administration (P<0.05). EH0202 (MACH) reduced blood pressure, excess facial skin blood flow (flushing) and abnormal lipid levels, as well as clinically improved menopausal symptoms in post-menopausal women. In post-menopausal women, this product appears to help maintain normal biological function and improves quality of life.


2019 ◽  
Vol 21 (4) ◽  
pp. 397
Author(s):  
Suelen Maiara Medeiros da Silva ◽  
Bárbara Cristovão Carminati ◽  
Valfredo De Almeida Santos Junior ◽  
Pablo Christiano Barboza Lollo

AbstractThe interest of the supplementation market for the soy protein consumption  to optimize physical and metabolic performance after exercise is increasing. However, evidence suggests that the  soy protein ingestion has lower anabolic properties when compared with whey protein. The purpose of this systematic review was to compare the effects of whey protein and soy protein supplementation on the  muscle functions maintenance after exercise. This review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Articles were searched for in the Pubmed database and included studies comparing the effects of soy protein and whey protein consumption on protein synthesis, lean mass gain and oxidative stress reduction in response to endurance or resistance training. Thirteen trials were included in this review. The results showed that the whey protein consumption is superior to that of soy protein with respect to protein synthesis and lean mass gain, but soy protein showed superior results in reducing oxidative stress. Future research comparing both soy and whey protein are needed to define protein source to be used in nutritional interventions to protein synthesis, lean mass gain and oxidative stress in different populations. Keywords: Soybean Proteins. Milk Proteins. Protein Biosynthesis. Hypertrophy. ResumoO interesse do mercado de suplementação pelo consumo de proteína de soja para otimizar o desempenho físico e metabólico após o exercício está aumentando. No entanto, evidências sugerem que a ingestão da proteína de soja tem propriedades anabólicas mais baixas quando comparada à proteína do soro do leite. O objetivo desta revisão sistemática foi comparar os efeitos da suplementação com whey protein e proteína de soja na manutenção das funções musculares após o exercício. Esta revisão foi realizada usando os Itens de Relatório Preferidos para Revisões Sistemáticas e Meta-Análises (PRISMA). Os artigos foram pesquisados na base de dados Pubmed e incluíram estudos comparando os efeitos da proteína de soja e do consumo de proteínas do soro na síntese protéica, ganho de massa magra e redução do estresse oxidativo em resposta ao treinamento de resistência ou resistência. Treze ensaios foram incluídos nesta revisão. Os resultados mostraram que o consumo de proteína de soro é superior ao da proteína de soja em relação à síntese protéica e ao ganho de massa magra, mas a proteína de soja apresentou resultados superiores na redução do estresse oxidativo. Pesquisas futuras comparando a soja e a proteína do soro do leite são necessárias para definir a fonte protéica a ser usada em intervenções nutricionais para a síntese protéica, ganho de massa magra e estresse oxidativo em diferentes populações. Palavras-chave: Proteínas de Soja. Proteínas do Leite. Biossíntese de Proteínas. Hipertrofia.


2021 ◽  
Author(s):  
Tomoharu Taga ◽  
Kayoko Ito ◽  
Kiyoshi Takamatsu ◽  
Mariko Ogawa ◽  
Saori Funayama ◽  
...  

Abstract Background: Perimenopausal women experience a wide variety of systemic symptoms: hot flashes, sweating, psychiatric symptoms and various oral sensory complaints (OSC). OSC in perimenopausal women include xerostomia, taste disturbance and burning mouth. However, the factors associated with these OSC have not been identified. The purpose of this investigation was to elucidate the factors associated with OSC in perimenopausal women.Methods: The study cohort comprised 43 perimenopausal women aged 45–55 years. Data on medical history, medications, menstrual status, menopausal symptoms, xerostomia, taste disturbance and burning mouth were collected. Volumes of unstimulated and stimulated saliva were measured. Tongue coating was evaluated according to a tongue coating index. Univariate analysis was performed to identify factors significantly associated with having xerostomia, taste disturbance, burning mouth and more than two OSC (2OSC). Next, the factors strongly associated with these symptoms were examined by logistic regression analysis.Results: The number of menopausal symptoms was significantly higher, and volume of unstimulated saliva significantly lower in participants with xerostomia, taste disturbance, burning mouth or 2OSC than in those without these characteristics. Agents targeting the central nervous system were more frequently taken by participants with burning mouth and 2OSC than by those without these characteristics. According to logistic regression analysis, the number of menopausal symptoms was an explanatory variable for xerostomia, taste disturbance, burning mouth and 2OSC. Conclusions: Our findings suggested that OSC associated with the number of menopausal symptoms. Management of menopausal symptoms may decrease OSC, leading to improved quality of life of perimenopausal women.


2009 ◽  
Vol 8 (7) ◽  
pp. 1009-1017 ◽  
Author(s):  
Gita Radhakrish ◽  
Rashmi . ◽  
Neera Agarwal ◽  
Neelam B. Vaid

2013 ◽  
Vol 7 (1) ◽  
pp. 11-14 ◽  
Author(s):  
TS Bag ◽  
Amit Kyal ◽  
DP Saha ◽  
R Dutta ◽  
S Mondal

A prospective case control study was conducted at Medical College, Kolkata with the aim of evaluating the role of isoflavone( a class of phytoestrogen –plant compounds having the beneficial effects of estrogen but lesser risks and side effects) in postmenopausal women. 100 postmenopausal women (those who underwent total abdominal hysterectomy and bilateral salpingooopherectomy for different benign indications, aged between 40-50 years and who were menstruating before operation) were alternately distributed into two groups-Group A (n=50, received 60mg of isoflavone and 500mg of calcium per day for 6 months) and Group B (n=50, received 500mg of calcium per day only for 6 months). To evaluate the menopausal symptoms, the menopausal Kupperman index questionnaire was applied. Other outcomes measured were body mass index, blood pressure and lipid profile. Menopausal symptoms in Group A(those using isoflavones) were lower compared to Group B. The present study showed that Kupperman index decreased significantly in Group A (from 28.48 ± 2.03 to 16.32 ± 1.06 i.e. 45% decline) compared to Group B (from 24.56 ± 1.52 to 18.44 ± 1.11 i.e. 25% decline). No differences in blood pressure or body mass index were found during treatment between the two groups. . In our study total cholesterol, triglycerides and low-density lipoproteins (LDL) decreased significantly in Group A compared to Group B. Therefore our clinical study indicates that isoflavone can be an invaluable resource for postmenopausal women for combating menopausal symptoms. Nepal Journal of Obstetrics and Gynaecology / Vol 7 / No. 1 / Issue 13 / Jan- June, 2012 / 11-14 DOI: http://dx.doi.org/10.3126/njog.v7i1.8826


2002 ◽  
Vol 76 (1) ◽  
pp. 165-171 ◽  
Author(s):  
James H Swain ◽  
D Lee Alekel ◽  
Sarah B Dent ◽  
Charles T Peterson ◽  
Manju B Reddy

2006 ◽  
Vol 16 (3) ◽  
pp. 233-244 ◽  
Author(s):  
Darren G. Candow ◽  
Natalie C. Burke ◽  
T. Smith-Palmer ◽  
Darren G. Burke

The purpose was to compare changes in lean tissue mass, strength, and myof-brillar protein catabolism resulting from combining whey protein or soy protein with resistance training. Twenty-seven untrained healthy subjects (18 female, 9 male) age 18 to 35 y were randomly assigned (double blind) to supplement with whey protein (W; 1.2 g/kg body mass whey protein + 0.3 g/kg body mass sucrose power, N = 9: 6 female, 3 male), soy protein (S; 1.2 g/kg body mass soy protein + 0.3 g/kg body mass sucrose powder, N = 9: 6 female, 3 male) or placebo (P; 1.2 g/kg body mass maltodextrine + 0.3 g/kg body mass sucrose powder, N = 9: 6 female, 3 male) for 6 wk. Before and after training, measurements were taken for lean tissue mass (dual energy X-ray absorptiometry), strength (1-RM for bench press and hack squat), and an indicator of myofbrillar protein catabolism (urinary 3-methylhistidine). Results showed that protein supplementation during resistance training, independent of source, increased lean tissue mass and strength over isocaloric placebo and resistance training (P < 0.05). We conclude that young adults who supplement with protein during a structured resistance training program experience minimal beneficial effects in lean tissue mass and strength.


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